Elshimaa Abdelhafez | Medicinal Chemistry | Best Researcher Award

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Dr. Elshimaa Abdelhafez | Medicinal Chemistry |Best Researcher Award

šŸ‘Øā€šŸ«Profile Summary

Elshimaa Abdelhafez is an accomplished academician with a strong background in Medicinal Chemistry. Holding a PhD from Minia University, Egypt, earned through the CHANNEL Program with Wake Forest University, USA, their research focuses on the synthesis, molecular modeling, and anticancer activity of organic compounds. With teaching experience since 2002, they have excelled as an Assistant Professor at Minia University, imparting knowledge in Medicinal and Organic Chemistry to undergraduate and postgraduate students. Their research experience spans mechanistic studies, chromatographic techniques, and computer-based drug design. Proficient in Arabic and English,Elshimaa Abdelhafez possesses excellent computer skills, making significant contributions to both academia and research.

šŸŒ Professional Profiles

Academic Qualifications šŸŽ“:

PhD Degree, Pharmaceutical Sciences (Medicinal Chemistry), December 2013, Minia University (Minia, Egypt) (Earned through CHANNEL Program between the School of Art and Science, Chemistry Dep., Wake Forest University, NC, USA, and Faculty of Pharmacy, El-Minia University) Thesis Advisor: Prof. Dr. Bruce King, Prof. of Chemistry, Wake Forest University, NC, USA Thesis entitled “Synthesis, Molecular Modeling and Anticancer Activity of New Reserpine Derivatives as Inducers of Mis-Match Repair Protein” Master Degree: in Pharmaceutical Sciences (Medicinal Chemistry), January 2008, Faculty of Pharmacy, Minia University (Minia, Egypt) Thesis Advisor: Prof. Dr. Hassan H. A, Farag, Prof. of Pharmaceutical Chemistry, former dean, Faculty of Pharmacy, Assiut University. Thesis entitled: “Synthesis and Investigation of Certain Derivatives Pyrazole-3-Carboxylic Acid as Novel Carriers for Nitric Oxide” B.Sc Degree: In Pharmaceutical Sciences, May 2002, Faculty of Pharmacy, El-Minia University Grade: Excellent with honor (88.23%)

Professional Positions šŸ‘©ā€šŸ«:

September 2002-December 2007: Teaching Assistant (demonstrator) at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. January 2008-May 2011: Assistant Lecturer at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. June 2011-June 2013: Research scholar at Prof. S. Bruce King Lab, Wake Forest University, Winston Salem, North Carolina, USA. June 2013-November 2013: Assistant Lecturer at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. December 2013-Current: Assistant Professor at Medicinal Chemistry department, Faculty of Pharmacy, Minia University.

Research Experiences šŸ§Ŗ:

Channel scholarship at Chemistry Department, Prof. Dr. Bruce King laboratory Wake Forest University, North Carolina, USA (June 2011-June 2013) Design and synthesis of organic compounds of potential biological activities Reaction mechanistic study Chromatographic techniques (Flash chromatography, Column Chromatography, and Preparative chromatography). Biological study of the synthesized compounds by the help of other institutions. Prodrug approaches as a tool for enhancing drug properties Structural elucidation of various groups of synthesized products using spectroscopic techniques including IR, NMR (ID and 2D), elemental analysis and MS (HRMS and ESI). Computer-based drug design including the pharmacophore and structure-based designs using MOE version 2014. Postgraduate research student (master and doctoral student), Faculty of Pharmacy, Minia University, Minia, Egypt (October 2002-May 2011) Synthesis of NO releasing compounds using different synthetic and separation technique for NO release measurement Some biological testing like anti-inflammatory and ulcerogenicity Principles of drug design software Good teaching experience for both organic and medicinal chemistry.

Teaching Experience šŸ“š:

Medicinal Chemistry Department, Faculty of Pharmacy, Minia University. Lecturer of Medicinal Chemistry (December 2013-current) Teaching theoretical Medicinal Chemistry courses for undergraduate pharmacy students (ANS, CNS, CVS, Drug Design, ā€¦.) Teaching theoretical Organic Chemistry courses for undergraduate pharmacy students (stereochemistry, spectroscopy, carboxylic acid & derivatives, heterocyclic chemistry, ..) Teaching Organic Spectroscopy for postgraduate pharmacy students (IR, NMR, Mass) Teaching Stereochemistry for clinical Pharmacy students. Teaching Advanced Medicinal Chemistry Course for postgraduate pharmacy students in Master degree of medicinal chemistry (special courses). Teaching Advanced Organic Chemistry Course for postgraduate pharmacy students in Master degree of medicinal chemistry(Special course). Organic Chemistry Department, Faculty of Pharmacy, Deraya University. Lecturer of Organic Chemistry (September 2015-Jan 2019) Teaching Organic Chemistry I & II courses for undergraduate pharmacy students (Introduction, stereochemistry, Heterocyclic Chemistry, Aromatic compounds, ā€¦.) Medicinal Chemistry Department, Faculty of Pharmacy, Minia University. Teaching Assistant. (September 2002-December 2013) Teaching practical Organic Chemistry courses. Teaching practical Medicinal Chemistry courses.

Skills šŸŒ:

  • Languages:
    • Arabic: mother tongue.
    • English: Excellent written and spoken)
  • Computer:
    • Excellent in windows, Word, PowerPoint, Internet, and Endnote
    • Very good in Excel and GraphPad Prism
    • (Passed ICDL exams ā€“ advanced ICTP, course exam)

 

šŸ“šTop Noted Publication

  1. M.G.A. Abd Elhalim, et al.
    • Title: Hemorrhoidectomy versus Hemorrhoidectomy with Internal Anal Sphincterotomy in Management of Hemorrhoids.

 

  1. S. Abdel Hafez, et al.
    • Title: The role of mast cells in accelerating our skin aging.

 

  1. E.-S.M. Abdel-Hafez, et al.
    • Title: Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide.

 

  1. A.M. Abdel-Hakem, E.-S.M. Abdelhafez, et al.
    • Title: Docking Studies Of Some E-2-Phenyl-4-(2-Phenylhydrazineylidene) Oxazol-5 (4H)-One Derivatives As A Potential Caspase-8 Inhibitor.

 

  1. E. Abdelhafez, et al.
    • Title: Comparing Open Preperitoneal Versus Laparoscopic Totally Extra Peritoneal Repair of Inguinal Hernia.

 

  1. E.-S.M.N. Abdelhafez, et al.
    • Title: Apoptotic inhibitors as therapeutic targets for cell survival.

 

  1. E.-S.M. AbdelHafez, et al.
    • Title: Synthesis, Molecular Modeling and Anticancer Activity of New Rescinnamine Derivatives as MMR-Inducers.

 

  1. E.M. AbdelHafez, et al.
    • Title: Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment.

 

  1. E.M. AbdelHafez, et al.
    • Title: Improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment.

 

  1. E.M.N. Abdelhafez, et al.
    • Title: Antimicrobial Activity of New Amide/thioamides Derivatives of Ciprofloxacin.

 

  1. E.S.M. AbdelHafez, et al.
    • Title: Lossen rearrangements under Heck reaction conditions.

 

  1. A.M. AbdelHakem, E.-S.M. Abdelhafez, et al.
    • Title: Current trends and future perspectives of antimutagenic agents.

 

  1. M. Abdullah, et al.
    • Title: Fluoroquinolones as urease inhibitors: anti-Proteus mirabilis activity and molecular docking studies.

Ruben Costa | bio-optoelectronics | Best Researcher Award

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Ā Prof Dr. Ruben Costa | bio-optoelectronics | Best Researcher Award

 

šŸŒŸ Profile Summary

šŸŒ RubĆ©n D. Costa, born in Spain in 1983, is a distinguished Full Professor and Vice Dean at TUM, Germany. Renowned for his groundbreaking work in biogenic functional materials, he holds a German Habilitation in Physical Chemistry and a Spanish Habilitation as a University Professor. An influential figure in sustainable optoelectronics, he boasts a prolific publication record of over 150 papers. Recognized with 38 awards, including the RSC Dalton Division Horizon Prize and ERC Consolidator, Dr. Costa is a committed educator, mentor, and an elected member of the Global Young Academy, reflecting his dedication to scientific excellence and societal engagement. šŸ†šŸ”¬šŸŒ±

 

šŸŒ Professional Profiles

šŸŽ“ Education

2022: German Habilitation in Physical Chemistry (U. Erlangen-NĆ¼rnberg), 2015: Spanish Habilitation – University Professor in Natural Science (Spanish Government; ANECA), 2010: PhD in Chemistry (Summa cum Laude) – U. Valencia. Advisors: Prof. OrtĆ­ and Dr. Bolink, 2006: Bachelor/Master in Chemistry – U. Valencia, Spain. Best student record: 1st regional/3rd national

šŸ‘Øā€šŸ« Current Position & šŸŒ Previous Positions

2022-: Vice Dean of Research and Innovation, TUM Campus Straubing, 2020-: Full Professor (W3), Chair of Biogenic Functional Materials; Technical University of Munich, 2018-2020: Associate Professor – Department of Applied Chemistry and Physics, U. Waseda, Japan, 2017-2020: Program Leader/Senior PI – IMDEA Materials, Spain, 2014-2017: Liebig group leader – Department of Physical Chemistry I, U. Erlangen-NĆ¼rnberg, Germany, 2011-2014: Humboldt fellow (2011-2013)/Senior post-doc (2013-2014) – Department of Physical Chemistry I, U. Erlangen-NĆ¼rnberg, Germany, 2007-2010: PhD fellow (FPU) – IcMol, Spain (Prof. OrtĆ­; Dr. Bolink)

šŸ“ Brief Description

Prof. Costa earned his B.Sc/M.Sc in Chemistry from U. Valencia in 2006 and completed his PhD at the Institute for Molecular Science at U. Valencia in 2010. From 2011 to 2013, he was a Humboldt Postdoctoral Researcher at U. Erlangen-Nuremberg, working on nanocarbon-based solar cells. In 2014, he obtained the Liebig Scholarship, heading the hybrid optoelectronic materials and devices lab at FAU. In 2017, he moved part of his group to IMDEA Materials (Spain) and further expanded it to U. Waseda (Japan) as Associate Professor in 2018. Since 2020, he is the Head of the Chair of Biogenic Functional Materials (W3; Full Professor) at TUM.

šŸ”¬ Scientific Figures

Number of publications (accepted/submitted): >150 (>105 corresponding since 2014), Number of publications in refereed scientific journals: >125 (>90% in Q1), Number of publications in refereed proceedings: 6, Number of publications in refereed industrial journals: 6, Reviews and perspectives: 15, Number of book chapters: 7, Number of patents: 5 since 2015, Author/Editor of books: 1 (2018 as editor and author), h-index: 49 (Google); 45 (Scopus), Number of citations: >7600 (>4000 since 2018; Google); >6400(>3350 since 2018; Scopus), Number of awards, mentions, and personal scholarships: 38 (14 since 2018), Number of contributions in workshops, conferences, lectures: >90 (>55 since 2018)

šŸ† Fellowships, Awards, and Recognitions

2023: Elected member of the Global Young Academy. Serving for a five-year term. Recognized for scientific excellence and societal engagement. 2022: RSC Dalton Division Horizon Prize 2022. Impactful work on sustainable copper(I) complexes for lighting. 2021: RSC Materials Chemistry Division Horizon Prize: Stephanie L Kwolek Award 2021. Recognizing the impact of protein-based lighting. 2021: Scientific Award Ateneo 2021. Honoring the best Spanish young scientists (<35) for scientific/social impact. 2020: Numerary Member of the Academia Joven de EspaƱa. Recognizing the best Spanish young scientists (<35 years old) for scientific/social impact. 2020: FPdGi research award by the Spanish Royal Family. Recognized as the best worldwide Spanish young scientist (<35 years old) for scientific impact. 2020: Fellow of the Royal Society of Chemistry (FRSC). Acknowledged for high-level accomplishments in Chemical Science. 2019: 100 Spanish Economic Leaders for Tomorrow on the Choiseul Institute Ranking. Recognizing leadership and contributions valuable for society’s future. 2019: FEMS Materials Science & Technology Prize. Awarded by the Federation of European Materials Societies for significant contributions in Materials Science and Technology. 2019: Young Researcher ChemPubSoc Award. Recognizing excellence in scientific contributions reported in journals of the ChemPubSoc. 2019: ERC-Consolidator by the European Research Council (Success rate <12%). 2018: Young Scientists 2018 by the World Economic Forum (WEF). Honor provided to world-wide top researchers (<35), shaping the future. 2018: Leonardo Fellowship 2018 by the BBVA Foundation. One of the most prestigious awards for mid-career researchers in Europe. 2018: XIII Science-Technology award Ciutat d’AlgemesĆ­. Recognizing the relevance of the scientific career of Valencia junior groups leaders. 2018-2023: Ramon y Cajal fellow by the Spanish Government. Highest honor for young researchers in Spain, highlighting the relevance and originality of their research. 2017: Innovationspreis der BioRegionen 2017 by AK BioRegionen. Recognizing the relevance of the Bio-LED concept within the biology field in Germany. 2017: European Innovator (Pioneer) 2017 under 35 by the MIT Technology Review. Highlighting disruptive and innovative contributions in Europe. 2017: Spanish Top Talent 2017 under 35 by the MIT Technology Review. Recognizing disruptive and innovative contributions in Spain. 2017: ADUC-Jahrespreis 2017 by the GDCh. Highest honor for young chemist leaders in Germany. 2017-2019: Liebig Stipendium by the Fonds des Verbandes der Chemischen Industrie 2016: LpS Scientific Award 2016 for emerging lighting technologies. Granted in the 6th annual LED professional Symposium +Expo (LpS). 2016: Silver Medal European Young Chemist Award 2016 by the European Association for Chemical and Molecular Sciences (EuChemMS). 2016: Young Chemist Award 2016 by RSEQ. Recognizing excellence and quality of the prospect of Spanish

šŸ“š Scientific Publication Record

160 accepted/submitted contributions divided into patents, reviews, book chapters, industrial papers, proceedings, and scientific publications.

 

šŸ‘©ā€šŸ« Supervision

  • Supervisor of PhD/MSc students with several completed and ongoing projects.

šŸŽ“ Teaching Activities

  • Lecturer at TUM, U. Navarra, U. Waseda, and more.
  • Erasmus mentor for international agreements.

šŸ”¬ Technology Transfer to Industry and Patents

  • PI of projects with Repsol (2018-2020; 431 kā‚¬).
  • Main author of 5 patents.

šŸ¤ Commissions of Trust and Memberships

  • Elected Member of the Global Young Academy, Ambassador of the European Climate Pact, Vice Dean of Research and Innovation at TUM Campus Straubing, and more.

šŸŒ International Reputation

95 contributions to conferences/seminars/exhibitions. 38 awards/grants at every level of his career. Elected member of various scientific communities. This summary highlights Prof. Costa’s extensive academic and research achievements, recognition in the scientific community, and contributions to teaching and mentorship.

šŸ“šTop Noted Publication

 

Khaled El-Adl | Pharmaceutical Chemistry | Best Researcher Award

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Ā Prof Dr. Khaled El-Adl | Pharmaceutical Chemistry | Best Researcher Award

 

šŸŒŸ Profile Summary

šŸ‘Øā€šŸ«šŸ§Ŗ With an impressive academic journey, I am a seasoned Professor of Pharmaceutical Chemistry at Al-Azhar University, Cairo, Egypt, achieving excellence at every academic milestone. šŸŽ“ My educational background includes a Ph.D. in Pharmaceutical Chemistry, highlighting my dedication to advancing the field. šŸ’” Over the years, I have honed my expertise through specialized scientific courses in Organic Chemistry, Mathematics, Statistics, and more. šŸŒ Additionally, my proficiency extends to molecular modeling and computer-aided drug design.

šŸŒŸ Currently serving as a Professor and Head of Pharmaceutical Chemistry Department at Heliopolis University, I have also held leadership roles, such as Manager of the Pharmaceutical Analytical Unit at Al-Azhar University. šŸ’¼ My experiences extend to consultancy in the Quality Committee of Central Administration of Pharmacists Affairs and serving as an Assistant Professor and Head of Pharmaceutical Chemistry Department at Heliopolis University.

šŸŒ My journey includes international experiences, such as being a Lecturer and Head of Pharmaceutical Chemistry Department at Omer Al-Mokhtar University in Libya. šŸ¤ Throughout my career, I’ve balanced teaching roles with real-world applications, working as a practicing pharmacist in Cairo, Egypt.

 

šŸŒ Professional Profiles

šŸŽ“ Qualifications

Prof. of Pharmaceutical Chemistry, Al-Azhar University, Cairo, Egypt (2019) Ass. Prof. of Pharmaceutical Chemistry, Al-Azhar University, Cairo, Egypt (2014) Ph.D. Pharm. Sci. (Pharmaceutical Chemistry), Al-Azhar University, Cairo, Egypt (2009) M. Pharm. Sci. (Pharmaceutical Chemistry), Al-Azhar University, Cairo, Egypt (2004) B. Pharm. Sci., Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt (1998) – Excellent with the grade of honor High School Degree (1993)

šŸ“š Courses

Scientific Courses Obtained: Preparatory courses in Organic Chemistry, Mathematics, Statistics, Computer Science, English, Physical Chemistry, and Instrumental Analysis. Special courses in Pharmaceutical Chemistry, Organic Chemistry, Analytical Chemistry, Molecular Modeling, and Computer-Aided Drug Design. English Course: TOEFL Certificate Educational Development Courses: Various courses including self-organizational evaluation, learning outcomes, curriculum maps, research preparation, examinations systems, presentation skills, crisis management, and more. All taken at National Authority for Quality Assurance and Accreditation of Education (NQAE) and Al-Azhar Quality Assurance and Training Center (AQATC).

šŸ‘Øā€šŸ« Scientific Courses Lecturer

Drug Design and Discovery, Drug Design of Natural Products, Organic Chemistry (Aliphatic, Aromatic, and Spectroscopy) Medicinal Chemistry courses

šŸ‘Øā€šŸŽ“ Experience

Prof. & Head of Pharmaceutical Chemistry Department, Pharmaceutical Chemistry, Faculty of Pharmacy, Heliopolis University, Cairo, Egypt (Dec. 2019 – Present) Manager of Pharmaceutical Analytical Unit, Al-Azhar University, Faculty of Pharmacy, Boys Branch, Nasr City, Cairo, Egypt (Feb. 2017 – Dec. 2018) Consultant in the Quality Committee of Central Administration of Pharmacists Affairs for Licensing of Virus C and Cancer Medications (Oct. 2017 – Mar. 2019) Ass. Prof. & Head of Pharmaceutical Chemistry Department, Pharmaceutical Chemistry, Faculty of Pharmacy, Heliopolis University, Cairo, Egypt (Dec. 2018 – Dec. 2019) Ass. Prof. of Pharmaceutical Chemistry, Nahda University, Faculty of Pharmacy, Benisuef, Egypt (Feb. 2018 – Aug. 2018) Ass. Prof. of Pharmaceutical Chemistry and Drug Design, Al-Azhar University, Faculty of Pharmacy, Boys Branch, Nasr City, Cairo, Egypt (Oct. 2014 – Jan. 2018) Lecturer of Pharmaceutical Chemistry and Drug Design, Al-Azhar University, Faculty of Pharmacy, Boys Branch, Nasr City, Cairo, Egypt (Jun. 2014 – Sept. 2014) Lecturer & Head of Pharmaceutical Chemistry Department, Omer Al-Mokhtar University – Faculty of Pharmacy, Derna City, Libya (May. 2012 – Jun. 2014) Lecturer of Pharmaceutical Chemistry and Pharmaceutics (Part-Timer), Faculty of Medical Technology, Derna City, Libya (May. 2012 – Jun. 2014)

 

šŸ† Academic Honor

National Science Fund for Distinguished Young Scholars, 2022 Young Excellence Award of Shanghai Bioinformatics Society, 2021 First Prize of Wu Wenjun Artificial Intelligence Natural Science Award, 2020

šŸ§‘ā€šŸ”¬ Research Interests

  • Pharmaceutical Chemistry
  • Drug Design
  • Stereochemistry

 

šŸ“šTop Noted Publication

Design, synthesis, molecular docking, and anticancer activity of benzoxazole derivatives as VEGFRā€2 inhibitors

Benzoxazole/benzothiazoleā€derived VEGFRā€2 inhibitors: design, synthesis, molecular docking, and anticancer evaluations

Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents

Design, synthesis, and anti-proliferative evaluation of new quinazolin-4 (3H)-ones as potential VEGFR-2 inhibitors

Discovery of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation

Design, synthesis, molecular modeling and biological evaluation of novel 2, 3-dihydrophthalazine-1, 4-dione derivatives as potential anticonvulsant agents

Discovery of new quinoxaline-2 (1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation

design, synthesis, molecular docking, and anticancer activity of phthalazine derivatives as VEGFRā€2 inhibitors

New quinoxaline-2 (1 H)-ones as potential VEGFR-2 inhibitors: Design, synthesis, molecular docking, ADMET profile and anti-proliferative evaluations

Design, synthesis, molecular docking and anticonvulsant evaluation of novel 6-iodo-2-phenyl-3-substituted-quinazolin-4 (3H)-ones

The antimicrobial potential and pharmacokinetic profiles of novel quinoline-based scaffolds: synthesis and in silico mechanistic studies as dual DNA gyrase and DHFR inhibitors