Somnath Paul | Cancer Immunotherapy | Best Researcher Award

Dr. Somnath Paul | Cancer Immunotherapy | Best Researcher Award

Staff Scientist, Washington University United States

Somnath Paul, Ph.D., is a Staff Scientist in the Department of Pathology and Immunology at Washington University in St. Louis, MO. With a robust academic and research career, he specializes in molecular genetics, epigenetics, and immunology. Over the years, Dr. Paul has contributed significantly to cancer research, developing new strategies for tumor profiling and immunotherapy. He has worked at prestigious institutions like the University of Texas MD Anderson Cancer Center and CSIR-Indian Institute of Chemical Biology, publishing several key research articles.

Profile

Scopus

Scholar

🎓 Education

Dr. Paul earned his Ph.D. in Molecular and Human Genetics from Jadavpur University, India (2016), after completing a Master’s in Genetics at the University of Calcutta (2008). He began his academic journey with a Bachelor’s in Physiology from Presidency College, University of Calcutta (2006). His educational foundation laid the groundwork for his research focus on epigenetics, immunology, and cancer biology.

💼 Experience

Dr. Paul’s professional career spans prestigious institutions, including Washington University (2024–Present), University of Texas MD Anderson Cancer Center (2020–2024), and CSIR-Indian Institute of Chemical Biology (2009–2016). His work focuses on immunotherapy, monoclonal antibody production, and the genetic regulation of cancer. He has been a postdoctoral fellow, research scientist, and project assistant, contributing to several groundbreaking research projects in molecular biology, toxicology, and immunology.

🏆 Awards and Honors

Dr. Paul has received notable accolades, such as the prestigious NIH-funded research project on INO80 chromatin remodeling. He was also honored with research excellence awards, including one from GEU, DDN in 2015, and the Early Career Research Award from SERB (2017). Additionally, he received travel grants from DST (2012) and presented a best paper at TriboIndia-2023 Conference.

🔬 Research Focus

Dr. Paul’s research is primarily centered on understanding tumor progression through circulatory tumor cell profiling, tumor remission and relapse monitoring, and novel monoclonal antibody development for immunotherapy. His work includes studying the infection dynamics of herpes viruses, epigenetic mechanisms of cancer, and identifying biomarkers for early disease detection. He aims to enhance therapeutic strategies through innovative platforms and experimental models.

🏆 Conclusion

Dr. Somnath Paul is a strong contender for the Best Researcher Award due to his robust academic and research portfolio, innovative contributions, and extensive publication record. Addressing the identified areas for improvement could further bolster his candidacy for this and similar accolades in the future.

Publication

  1. Arsenic exposure through drinking water increases the risk of liver and cardiovascular diseases in the population of West Bengal, India
    Year: 2012
    Authors: N Das, S Paul, D Chatterjee, N Banerjee, NS Majumder, N Sarma, TJ Sau, …
    Citations: 150

 

  1. Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2
    Year: 2013
    Authors: P Bhattacharjee, S Paul, M Banerjee, D Patra, P Banerjee, N Ghoshal, …
    Citations: 104

 

  1. Loss of Snf5 Induces Formation of an Aberrant SWI/SNF Complex
    Year: 2017
    Authors: P Sen, J Luo, A Hada, SG Hailu, ML Dechassa, J Persinger, S Brahma, …
    Citations: 99

 

  1. The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
    Year: 2018
    Authors: S Brahma, M Ngubo, S Paul, M Udugama, B Bartholomew
    Citations: 81

 

  1. Arsenic-induced toxicity and carcinogenicity: a two-wave cross-sectional study in arsenicosis individuals in West Bengal, India
    Year: 2012
    Authors: S Paul, N Das, P Bhattacharjee, M Banerjee, JK Das, N Sarma, A Sarkar, …
    Citations: 78

 

  1. Arsenic-induced promoter hypomethylation and over-expression of ERCC2 reduces DNA repair capacity in humans by non-disjunction of the ERCC2/Cdk7 complex
    Year: 2014
    Authors: S Paul, N Banerjee, A Chatterjee, TJ Sau, JK Das, PK Mishra, …
    Citations: 65

 

  1. Recent advances in arsenic research: significance of differential susceptibility and sustainable strategies for mitigation
    Year: 2020
    Authors: T Sanyal, P Bhattacharjee, S Paul, P Bhattacherjee
    Citations: 62

 

  1. Epimutagenesis: A prospective mechanism to remediate arsenic-induced toxicity
    Year: 2015
    Authors: S Paul, AK Giri
    Citations: 52

 

  1. Risk of Occupational exposure to Asbestos, Silicon and Arsenic on Pulmonary Disorders: Understanding the Genetic-Epigenetic Interplay and Future Prospects.
    Year: 2016
    Authors: P Bhattacharjee, S Paul, P Bhattacharjee
    Citations: 47

 

  1. Epigenetic Modifications of DAPK and p16 Genes Contribute to Arsenic-Induced Skin Lesions and Non-Dermatological Health Effects
    Year: 2013
    Authors: N Banerjee, S Paul, TJ Sau, JK Das, A Bandyopadhyay, AK Giri
    Citations: 44

 

 

Di Zhu| Immuno-oncology| Best Researcher Award

Mr. Di Zhu| Immuno-oncology| Best Researcher Award

Professor at Fudan University,  China

Di Zhu is a Professor in the Department of Pharmacology at Fudan University, specializing in immuno-oncology and cancer research. Born on October 13, 1983, he holds a Ph.D. in Biochemistry and Molecular Biology. With over 8 years of academic experience, he has pioneered groundbreaking therapies targeting colorectal cancer. Recognized globally for his contributions to cancer immunotherapy, he combines innovative research with clinical applications to improve patient outcomes.

Profile

Scholar

Education 🎓

Ph.D. in Biochemistry & Molecular Biology (2005–2010), Shanghai Institute of Biochemistry and Cell Biology, CAS. Postdoctoral Fellow (2011–2015), Dana-Farber Cancer Institute, Harvard University. Undergraduate studies at Shandong University, earning accolades like the National Sci. & Tech. Challenge Cup (2004).

Experience 💼

Researcher: Fudan University, School of Basic Medical Sciences (2021–Present). Researcher: Minhang & Zhongshan Hospitals, Fudan University (2017–Present). Researcher: Fudan University, School of Pharmacy (2016–2021). Led 12 projects, supervised 16 research scholars, and organized 5 workshops globally.

Awards and Honors 🏅

Gold Medal: Global Life & Health Technology Concept Validation (2024). Excellence Award: Hai Ju Ying Cai Global Innovation (2024). Outstanding Young Scientist: Shanghai Society of Biotechnology (2022). 1000 Talent Young Award: CPC Central Committee (2016). Multiple national and international recognitions for cancer research.

Research Focus 🔬

Therapies: Pioneered BCL9/β-catenin inhibitors for colorectal cancer. Immunotherapy: Enhanced T-cell responses and reduced immune resistance. Innovative Molecules: Developed selective inhibitors for challenging pathways. Publications: Authored impactful research in top journals, advancing cancer treatment.

Conclusion

Dr. Di Zhu exemplifies the qualities of a world-class researcher. His groundbreaking contributions to cancer therapy, robust academic output, and numerous accolades strongly support his nomination for the Best Researcher Award, affirming his leadership and innovation in the field of pharmacology and immuno-oncology.

Publication

 

  • Clinical cancer immunotherapy: Current progress and prospects
    Authors: C Liu, M Yang, D Zhang, M Chen, D Zhu
    Journal: Frontiers in Immunology 13, 961805
    Citations: 140 (2022)

 

  • Wnt signaling pathway in cancer immunotherapy
    Authors: Y Zhou, J Xu, H Luo, X Meng, M Chen, D Zhu
    Journal: Cancer Letters 525, 84-96
    Citations: 125 (2022)

 

  • IFNα potentiates anti–PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
    Authors: B Hu et al., including D Zhu
    Journal: Cancer Discovery 12 (7), 1718-1741
    Citations: 123 (2022)

 

  • The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
    Authors: DI Zhu et al.
    Journal: Nature Medicine 21 (6), 572-580
    Citations: 116 (2015)

 

  • Pharmacological inhibition of β-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells
    Authors: M Feng et al., including D Zhu
    Journal: Science Advances 5 (5), eaau5240
    Citations: 100 (2019)

 

  • Cyclophilin A and CD147: Novel therapeutic targets for the treatment of COVID-19
    Authors: C Liu, A von Brunn, D Zhu
    Journal: Medicine in Drug Discovery 7, 100056
    Citations: 91 (2020)

 

  • T-cell-based immunotherapy in colorectal cancer
    Authors: M Feng, Z Zhao, M Yang, J Ji, D Zhu
    Journal: Cancer Letters 498, 201-209
    Citations: 67 (2021)

 

  • Targeting the tumor immune microenvironment for cancer therapy in human gastrointestinal malignancies
    Authors: Y Zhang et al., including D Zhu
    Journal: Cancer Letters 458, 123-135
    Citations: 55 (2019)

 

  • Targeting Cyclophilin A and CD147 to Inhibit Replication of SARS-CoV-2 and SARS-CoV-2-Induced Inflammation
    Authors: F Yang et al., including D Zhu
    Journal: Molecular Pharmacology
    Citations: 1 (2023)

 

  • New Approaches Targeting Immuno-oncology and Tumor Microenvironment
    Authors: D Zhu, F He
    Book Chapter: Cancer Treatment: An Interdisciplinary Approach, 63-90
    Citations: 1 (2022)