Andres Felipe Yepes Perez| Medicinal Chemistry

👨‍🏫Assoc Prof Dr Andres Felipe Yepes Perez an Assoc Prof Dr at University of Antioquia University, Department of Medicinal Chemistry, stands as a distinguished Academician/Research Scholar in the domain of Chemistry. Holding a  PhD in Chemistry INDUSTRIAL UNIVERSITY OF SANTANDER, their professional journey exemplifies dedication and expertise. 📚

🌐 Professional Profiles:

• Scopus Profile
• Scholar Profile

🎓 Qualifications:

Dr. Alberto Fernando Yepes boasts an extensive academic background and a prominent career in Chemistry. His educational journey began at the Industrial University of Santander, where he earned his Bachelor’s degree in Chemistry in 1998. He further pursued a Master’s degree in Chemistry in 2005 and a Ph.D. in Chemistry in 2011, both from the same institution. Dr. Yepes continued to refine his expertise through a Postdoctoral position at the Federal University of Rio de Janeiro in 2015.

👨‍🏫 Positions Held in the Last 5 Years

🏫 Over the past five years, Dr. Yepes has held influential roles contributing significantly to academia and research. Starting in 2023, he serves as a Professor and Researcher at the Institute of Chemistry, University of Antioquia. Prior to this, he served as a Teacher and Researcher at Tecnológico de Antioquia, Department of Basic Sciences, from 2016 until the beginning of 2023. His earlier experiences include a Postdoctoral Degree at the Federal University of Rio de Janeiro from 2012 to 2015.

🔬 Skills & Expertise:

Dr. Yepes possesses a diverse skill set and current expertise spanning Organic Synthesis, Medicinal Chemistry, Spectroscopy, and various applications in Cancer, Neurodegenerative diseases, Parasitic diseases, Pharmacology, Chemistry of natural products, Biochemistry, Computational chemistry, Bio-informatics studies, SAR, QSAR, and Docking.

 

Top Noted Publications:

• “Hybrid Molecules: Promising Compounds for the Development of New Treatments Against Leishmaniasis and Chagas Disease“ (Cardona-G W, Yepes AF, Herrera-R A. Curr Med Chem, 2018) focused on developing novel compounds to combat these diseases.
• “Molecular Docking and In Silico Studies of Potential Inhibitors for the Phosphotransferase System of Streptococcus mutans“ (Yepes A.F; MC Martinez-Pabon; Wbeimar A RiveraPérez. Archives of Oral Biology) explored inhibitors’ physicochemical properties.
• “Synthesis, Anti-parasitic Activity, and QSAR Study of a New Library of Polysubstituted Tetrahydronaphtho[1,2-b]azepines“ (Yépes, A.F., Bahsas, A., Escobar, P.,Palma, A. Garro Martinez, J.C., Enriz, R. Medicinal Chemistry Research, 2018) contributed to assessing anti-parasitic effects.
• “Chalcone-Quinoline Conjugates as Potential T. cruzi Cruzipain Inhibitors“ (ChemistrySelect, 2020) delved into inhibitory studies against T. cruzi Cruzipain.
• “The Hydroalcoholic Extract of Uncaria tomentosa (Cat’s Claw) Inhibits SARS-CoV-2 In Vitro“ (Evidence-Based Complementary and Alternative Medicine, 2021) showcased the extract’s potential against SARS-CoV-2.
• “Novel Multipotent Amantadine−M30D Hybrids as Effective Anti-Alzheimer’s Agents“ (ACS Chemical Neuroscience, 2022) focused on neuroprotective compounds.
• “Uncaria tomentosa (Cat’s Claw): A Promising Herbal Medicine Against SARS-CoV-2“ (J Biomol Struct Dyn, 2022) emphasized its potential as a herbal remedy against SARS-CoV-2.

• “Discovery of novel neuroprotective cinnamoyl-M30D hybrids targeting Alzheimer’s disease“ (Medicinal Chemistry Research, 2022) presents new compounds with neuroprotective potential against Alzheimer’s disease.
• “Chemopreventive Effect on Human Colon Adenocarcinoma Cells of Styrylquinolines: Synthesis, Cytotoxicity, Proapoptotic Effect, and Molecular Docking Analysis“ (Molecules, 2022) investigates the potential chemopreventive effects of styrylquinolines on colon adenocarcinoma cells.
• “Proapoptotic Effect and Molecular Docking Analysis of Curcumin-Resveratrol Hybrids in Colorectal Cancer Chemoprevention“ (Molecules, 2022) explores the proapoptotic effects of curcumin-resveratrol hybrids in preventing colorectal cancer.
• “New Heterofused Thiazolo/Pyrazinedione Hybrids as Promising Building Blocks for Anticancer Drug Development: Synthesis, Biological, and Drug-Likeness Evaluation“ (ChemistrySelect, 2023) focuses on the synthesis and evaluation of heterofused compounds for potential anticancer drug development.
• “Synthesis and In Silico Drug-Likeness Modeling of 5-FU/ASA Hybrids“ (Molbank 2023) involves the synthesis and computational modeling of hybrids combining 5-fluorouracil (5-FU) and acetylsalicylic acid (ASA) for drug likeness evaluation.