Elshimaa Abdelhafez | Medicinal Chemistry | Best Researcher Award

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Dr. Elshimaa Abdelhafez | Medicinal Chemistry |Best Researcher Award

šŸ‘Øā€šŸ«Profile Summary

Elshimaa Abdelhafez is an accomplished academician with a strong background in Medicinal Chemistry. Holding a PhD from Minia University, Egypt, earned through the CHANNEL Program with Wake Forest University, USA, their research focuses on the synthesis, molecular modeling, and anticancer activity of organic compounds. With teaching experience since 2002, they have excelled as an Assistant Professor at Minia University, imparting knowledge in Medicinal and Organic Chemistry to undergraduate and postgraduate students. Their research experience spans mechanistic studies, chromatographic techniques, and computer-based drug design. Proficient in Arabic and English,Elshimaa Abdelhafez possesses excellent computer skills, making significant contributions to both academia and research.

šŸŒ Professional Profiles

Academic Qualifications šŸŽ“:

PhD Degree, Pharmaceutical Sciences (Medicinal Chemistry), December 2013, Minia University (Minia, Egypt) (Earned through CHANNEL Program between the School of Art and Science, Chemistry Dep., Wake Forest University, NC, USA, and Faculty of Pharmacy, El-Minia University) Thesis Advisor: Prof. Dr. Bruce King, Prof. of Chemistry, Wake Forest University, NC, USA Thesis entitled “Synthesis, Molecular Modeling and Anticancer Activity of New Reserpine Derivatives as Inducers of Mis-Match Repair Protein” Master Degree: in Pharmaceutical Sciences (Medicinal Chemistry), January 2008, Faculty of Pharmacy, Minia University (Minia, Egypt) Thesis Advisor: Prof. Dr. Hassan H. A, Farag, Prof. of Pharmaceutical Chemistry, former dean, Faculty of Pharmacy, Assiut University. Thesis entitled: “Synthesis and Investigation of Certain Derivatives Pyrazole-3-Carboxylic Acid as Novel Carriers for Nitric Oxide” B.Sc Degree: In Pharmaceutical Sciences, May 2002, Faculty of Pharmacy, El-Minia University Grade: Excellent with honor (88.23%)

Professional Positions šŸ‘©ā€šŸ«:

September 2002-December 2007: Teaching Assistant (demonstrator) at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. January 2008-May 2011: Assistant Lecturer at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. June 2011-June 2013: Research scholar at Prof. S. Bruce King Lab, Wake Forest University, Winston Salem, North Carolina, USA. June 2013-November 2013: Assistant Lecturer at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. December 2013-Current: Assistant Professor at Medicinal Chemistry department, Faculty of Pharmacy, Minia University.

Research Experiences šŸ§Ŗ:

Channel scholarship at Chemistry Department, Prof. Dr. Bruce King laboratory Wake Forest University, North Carolina, USA (June 2011-June 2013) Design and synthesis of organic compounds of potential biological activities Reaction mechanistic study Chromatographic techniques (Flash chromatography, Column Chromatography, and Preparative chromatography). Biological study of the synthesized compounds by the help of other institutions. Prodrug approaches as a tool for enhancing drug properties Structural elucidation of various groups of synthesized products using spectroscopic techniques including IR, NMR (ID and 2D), elemental analysis and MS (HRMS and ESI). Computer-based drug design including the pharmacophore and structure-based designs using MOE version 2014. Postgraduate research student (master and doctoral student), Faculty of Pharmacy, Minia University, Minia, Egypt (October 2002-May 2011) Synthesis of NO releasing compounds using different synthetic and separation technique for NO release measurement Some biological testing like anti-inflammatory and ulcerogenicity Principles of drug design software Good teaching experience for both organic and medicinal chemistry.

Teaching Experience šŸ“š:

Medicinal Chemistry Department, Faculty of Pharmacy, Minia University. Lecturer of Medicinal Chemistry (December 2013-current) Teaching theoretical Medicinal Chemistry courses for undergraduate pharmacy students (ANS, CNS, CVS, Drug Design, ā€¦.) Teaching theoretical Organic Chemistry courses for undergraduate pharmacy students (stereochemistry, spectroscopy, carboxylic acid & derivatives, heterocyclic chemistry, ..) Teaching Organic Spectroscopy for postgraduate pharmacy students (IR, NMR, Mass) Teaching Stereochemistry for clinical Pharmacy students. Teaching Advanced Medicinal Chemistry Course for postgraduate pharmacy students in Master degree of medicinal chemistry (special courses). Teaching Advanced Organic Chemistry Course for postgraduate pharmacy students in Master degree of medicinal chemistry(Special course). Organic Chemistry Department, Faculty of Pharmacy, Deraya University. Lecturer of Organic Chemistry (September 2015-Jan 2019) Teaching Organic Chemistry I & II courses for undergraduate pharmacy students (Introduction, stereochemistry, Heterocyclic Chemistry, Aromatic compounds, ā€¦.) Medicinal Chemistry Department, Faculty of Pharmacy, Minia University. Teaching Assistant. (September 2002-December 2013) Teaching practical Organic Chemistry courses. Teaching practical Medicinal Chemistry courses.

Skills šŸŒ:

  • Languages:
    • Arabic: mother tongue.
    • English: Excellent written and spoken)
  • Computer:
    • Excellent in windows, Word, PowerPoint, Internet, and Endnote
    • Very good in Excel and GraphPad Prism
    • (Passed ICDL exams ā€“ advanced ICTP, course exam)

 

šŸ“šTop Noted Publication

  1. M.G.A. Abd Elhalim, et al.
    • Title: Hemorrhoidectomy versus Hemorrhoidectomy with Internal Anal Sphincterotomy in Management of Hemorrhoids.

 

  1. S. Abdel Hafez, et al.
    • Title: The role of mast cells in accelerating our skin aging.

 

  1. E.-S.M. Abdel-Hafez, et al.
    • Title: Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide.

 

  1. A.M. Abdel-Hakem, E.-S.M. Abdelhafez, et al.
    • Title: Docking Studies Of Some E-2-Phenyl-4-(2-Phenylhydrazineylidene) Oxazol-5 (4H)-One Derivatives As A Potential Caspase-8 Inhibitor.

 

  1. E. Abdelhafez, et al.
    • Title: Comparing Open Preperitoneal Versus Laparoscopic Totally Extra Peritoneal Repair of Inguinal Hernia.

 

  1. E.-S.M.N. Abdelhafez, et al.
    • Title: Apoptotic inhibitors as therapeutic targets for cell survival.

 

  1. E.-S.M. AbdelHafez, et al.
    • Title: Synthesis, Molecular Modeling and Anticancer Activity of New Rescinnamine Derivatives as MMR-Inducers.

 

  1. E.M. AbdelHafez, et al.
    • Title: Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment.

 

  1. E.M. AbdelHafez, et al.
    • Title: Improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment.

 

  1. E.M.N. Abdelhafez, et al.
    • Title: Antimicrobial Activity of New Amide/thioamides Derivatives of Ciprofloxacin.

 

  1. E.S.M. AbdelHafez, et al.
    • Title: Lossen rearrangements under Heck reaction conditions.

 

  1. A.M. AbdelHakem, E.-S.M. Abdelhafez, et al.
    • Title: Current trends and future perspectives of antimutagenic agents.

 

  1. M. Abdullah, et al.
    • Title: Fluoroquinolones as urease inhibitors: anti-Proteus mirabilis activity and molecular docking studies.