Mr. Di Zhu| Immuno-oncology| Best Researcher Award

Professor at Fudan University,  China

Di Zhu is a Professor in the Department of Pharmacology at Fudan University, specializing in immuno-oncology and cancer research. Born on October 13, 1983, he holds a Ph.D. in Biochemistry and Molecular Biology. With over 8 years of academic experience, he has pioneered groundbreaking therapies targeting colorectal cancer. Recognized globally for his contributions to cancer immunotherapy, he combines innovative research with clinical applications to improve patient outcomes.

Profile

Scholar

Education 🎓

Ph.D. in Biochemistry & Molecular Biology (2005–2010), Shanghai Institute of Biochemistry and Cell Biology, CAS. Postdoctoral Fellow (2011–2015), Dana-Farber Cancer Institute, Harvard University. Undergraduate studies at Shandong University, earning accolades like the National Sci. & Tech. Challenge Cup (2004).

Experience 💼

Researcher: Fudan University, School of Basic Medical Sciences (2021–Present). Researcher: Minhang & Zhongshan Hospitals, Fudan University (2017–Present). Researcher: Fudan University, School of Pharmacy (2016–2021). Led 12 projects, supervised 16 research scholars, and organized 5 workshops globally.

Awards and Honors 🏅

Gold Medal: Global Life & Health Technology Concept Validation (2024). Excellence Award: Hai Ju Ying Cai Global Innovation (2024). Outstanding Young Scientist: Shanghai Society of Biotechnology (2022). 1000 Talent Young Award: CPC Central Committee (2016). Multiple national and international recognitions for cancer research.

Research Focus 🔬

Therapies: Pioneered BCL9/β-catenin inhibitors for colorectal cancer. Immunotherapy: Enhanced T-cell responses and reduced immune resistance. Innovative Molecules: Developed selective inhibitors for challenging pathways. Publications: Authored impactful research in top journals, advancing cancer treatment.

Conclusion

Dr. Di Zhu exemplifies the qualities of a world-class researcher. His groundbreaking contributions to cancer therapy, robust academic output, and numerous accolades strongly support his nomination for the Best Researcher Award, affirming his leadership and innovation in the field of pharmacology and immuno-oncology.

Publication

 

• Clinical cancer immunotherapy: Current progress and prospects
  Authors: C Liu, M Yang, D Zhang, M Chen, D Zhu
  Journal: Frontiers in Immunology 13, 961805
  Citations: 140 (2022)

 

• Wnt signaling pathway in cancer immunotherapy
  Authors: Y Zhou, J Xu, H Luo, X Meng, M Chen, D Zhu
  Journal: Cancer Letters 525, 84-96
  Citations: 125 (2022)

 

• IFNα potentiates anti–PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
  Authors: B Hu et al., including D Zhu
  Journal: Cancer Discovery 12 (7), 1718-1741
  Citations: 123 (2022)

 

• The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
  Authors: DI Zhu et al.
  Journal: Nature Medicine 21 (6), 572-580
  Citations: 116 (2015)

 

• Pharmacological inhibition of β-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells
  Authors: M Feng et al., including D Zhu
  Journal: Science Advances 5 (5), eaau5240
  Citations: 100 (2019)

 

• Cyclophilin A and CD147: Novel therapeutic targets for the treatment of COVID-19
  Authors: C Liu, A von Brunn, D Zhu
  Journal: Medicine in Drug Discovery 7, 100056
  Citations: 91 (2020)

 

• T-cell-based immunotherapy in colorectal cancer
  Authors: M Feng, Z Zhao, M Yang, J Ji, D Zhu
  Journal: Cancer Letters 498, 201-209
  Citations: 67 (2021)

 

• Targeting the tumor immune microenvironment for cancer therapy in human gastrointestinal malignancies
  Authors: Y Zhang et al., including D Zhu
  Journal: Cancer Letters 458, 123-135
  Citations: 55 (2019)

 

• Targeting Cyclophilin A and CD147 to Inhibit Replication of SARS-CoV-2 and SARS-CoV-2-Induced Inflammation
  Authors: F Yang et al., including D Zhu
  Journal: Molecular Pharmacology
  Citations: 1 (2023)

 

• New Approaches Targeting Immuno-oncology and Tumor Microenvironment
  Authors: D Zhu, F He
  Book Chapter: Cancer Treatment: An Interdisciplinary Approach, 63-90
  Citations: 1 (2022)