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Jinhai Huang | Microbiology | Best Researcher Award

👨‍🏫jinhai Huang,  Prof Dr at University of Tianjin University China, stands as a distinguished Academician/Research Scholar in the domain of Veterinary Science and Veterinary Medicine. Holding a Ph.D., China Agriculture University , their professional journey exemplifies dedication and expertise. 📚

🌐 Professional Profiles:

Education Experience 📚

Visiting scholar at the University of Minnesota. 2001-2004: Ph.D. from China Agriculture University. 1994-1997: M.Sc. in the Department of Veterinary Medicine, Northwest Agricultural and Forestry University, China. 1989-1994: B.V.Sc. in the Department of Veterinary Medicine, Northwest Agricultural and Forestry University, China.


Professional Experience 👨‍🔬

06/2016 – Present: Professor at the School of Life Sciences, Tianjin University. 10/2004 – 06/2016: Associate Professor at the School of Chemical Engineering, Tianjin University. 07/1997 – 09/2002: Intern researcher (1997), Assistant Research Fellow (1988), Associate Research Fellow (2002) at the Tianjin Institute of Animal Science and Veterinary Medicine, Academy of Agricultural Sciences, Tianjin, China.


Research Area 🔬

Dr. Huang focuses on understanding the pathogenic and immunological mechanisms between microorganisms (viruses, bacteria, and their toxin products) and their hosts. His primary areas of interest include: Immunobiology: Identifying and understanding novel immune cells and their marker molecules, analyzing big omics data to discover new molecules’ roles in innate and adaptive immunity regulation, designing innate immune regulatory circuits, and remodeling cellular pathways. Microbial Synthetic Biology: Involves the design, construction, metabolic regulation, and health reshaping mechanisms of engineered probiotics, large-scale transformation and reconstruction technology of microbial genomes, research and development of oral mucosal vaccines, and constructing new vaccine design and manufacturing technologies. Pathogenic and Innate Immune Mechanisms: Understanding the pathogenic and innate immune mechanisms of microbial infections, focusing on immune escape from viral infections, rapid rescue of animal viruses, developing engineering vaccines, and constructing predictive vaccinology theory platforms for anti-infection immunity.Dr. Huang’s work aims to elucidate the mechanisms underlying pathogen-host interactions, improve vaccine development, and develop strategies for disease control to enhance human and animal health.


Top Noted Publications 📚:

H9N2 Avian Influenza Vaccine:  Recombinant hemagglutinin protein and DNA-RNA-combined nucleic acid vaccines harbored by yeast elicit protective immunity against H9N2 avian influenza infection. Published in Poultry Science, 2023.


Oral Immunization against Infectious Bursal Disease Virus:  Oral Immunization with Recombinant Saccharomyces cerevisiae Induces Specific Antibodies and Protective Immunity against Infectious Bursal Disease Virus. Published in Vaccines, 2023.


Inhibition of PRRS Virus Proliferation:  N-Acetyltransferase 9 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Proliferation by N-Terminal Acetylation of Structural Protein GP5. Published in Microbiology Spectrum, 2023.


PRRSV Mechanisms and Immunity:  PRRSV Non-Structural Proteins Promote PRRSV Proliferation via Ubiquitin Ligase RNF122. Published in Viruses, 2022.


Geese Astrovirus Genome Sequencing:  Complete Genome Sequence and Phylogenetic Analysis of a Goose Astrovirus Isolate in China. Published in Brazilian Journal of Microbiology, 2022.


Tat/pDNA-Ca2+ Nanoparticles in Ovarian Cancer Therapy:  Cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ Nanoparticles in Ovarian Cancer. Published in Journal of Nanobiotechnology, 2022.


Structure of Porcine Deltacoronavirus Protease:  Structure of the Porcine Deltacoronavirus Main Protease for Antiviral Design. Published in Viruses, 2022.


Adenovirus 4 Vaccine Development: Oral Immunization of Fiber-2 of Fowl Adenovirus Serotype 4 Provides Protective Immunity. Published in Veterinary Microbiology, 2022.


Oral SARS-CoV-2 Spike Protein Vaccine: Oral SARS-CoV-2 Spike Protein Recombinant Yeast Candidate Prompts Antibody and Gut Microbiota Changes in Mice. Published in Frontiers in Microbiology, 2022.


Additional PRRSV Research:  PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 for Proliferation. Published in Viruses, 2022.


jinhai Huang| Microbiology | Best Researcher Award

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