Research Interests 🧪
Our research focuses on probiotics, particularly lactic acid bacteria, that can produce bacteriocins, vitamins, and extracellular polysaccharides, among other substances, as well as their application in the food industry. We are aiming to understand the mechanism by which bacteriocins act against foodborne pathogens, the regulation of probiotic-derived metabolites (such as bacteriocins, folate, VB12, etc.) on the gastrointestinal (GI) microbiota, and the impact of functional lactic acid bacteria on immunity.
Education and Work Experiences 🎓🌐
Zhejiang Gongshang University, China (2023.01-Now), Zhejiang Gongshang University, China (2017.12-Now), Zhejiang Gongshang University, China (2015.03-2017.12), Florida State University, USA (2009.10-2014.10), Zhejiang University, China (2003.09-2009.03)
Grants (where I am/was the project leader in bold) 💰
[1] National Natural Science Foundation of China, Regulatory effect and molecular mechanism of a bacteriocin derived from lactic acid bacteria (Plantaricin JK) on the intestinal epithelial barrier (32272301)，2023.01-2026.12. Budget: RMB￥550,000. [2] National Natural Science Foundation of China，Lactic acid bacteria derived 5-methyltetrahydrofolate regulates the gut microflora and its molecular mechanism (31972974)，2020.01-2023.12. Budget: RMB￥580,000. [4] The Outstanding Young Scholars Program of Zhejiang Natural Science Foundation, Molecular mechanism of lactic acid bacteria-derived bacteriocins in regulating intestinal microbiota and inhibiting intestinal inflammation in IBD(LR22C200005)，2022.01-2024.12. Budget: RMB￥800,000. [5] Major Science and Technology Projects of Zhejiang Province, Screening of Bacteriocin-producing lactic acid bacteria and key technologies for industrialization, 2020.01-2022.12. Budget: RMB￥5000,000.
Awards 🏆
Second prize of National Science and Technology Progress Award, Functional lactic acid bacteria and the key technology of industrialization, 2019, 5/10. Second prize of Zhejiang Science and Technology Progress Award, Key technologies and industrialization of hierarchical intelligent manufacturing and steady-state application of active ingredients from Zhejiang specialty plants, 2023, 2/9. First prize of Zhejiang Science and Technology Progress Award, Application of functional Lactic acid bacteria (producing bacteriocin, B vitamins, etc.) in the dairy products, 2017, 3/12. Second prize of Science and technology innovation award of China Food Science and Technology Society, Characterization of extracellular vitamin B12 producing Lactobacillus plantarum strains and assessment of the probiotic potentials, 2017, 1/5.
Management, organization, memberships of committees 🤝
2023.09 Committee Member of the Academic Committee, Zhejiang Gongshang University 2023.05 Deputy Director of the Dairy Processing Committee, Zhejiang Dairy Industry Association 2022.08 Third Council Member of the Probiotics Branch, Chinese Society of Food Science and Technology 2023.09 Executive Vice President of the Green Valley Food and Health Industry Research Institute, Zhejiang Gongshang University 2022.05 Editorial Board Member of Advanced Gut & Microbiome Research 2022.01 Guest Associate Editor of the special issue of“Rising stars in Microbiome in Health and Disease: 2022”, Frontiers in Cellular and Infection Microbiology 2021.10 Guest Associate Editor of the special issue “Rising stars in Microbiome in Health and Disease: 2022” in Frontiers in Cellular and Infection Microbiology. 2021.12 Frontiers in Cellular and Infection Microbiology, Review Editor 2020.08 Committee Member of the Microbiology Professional Committee, Zhejiang Bioinformatics Society. 2019.02 Frontiers in Immunology, Review Editor
Patents 📜
A total of 11 granted invention patents have been achieved. (See the original content for detailed patent information) This content provides an overview of the researcher’s academic journey, research interests, grants, awards, and contributions to academic committees and editorial boards.