Kun Chang | Urological Oncology| Best Researcher Award

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 Dr. Kun Chang| Urological Oncology | Best Researcher Award

 

πŸ‘¨β€πŸ«Professional Summary πŸŒŸ

πŸŽ“ Ph.D. graduate in Urological Oncology with expertise in Ubiquitination and Tumorigenesis from Fudan University, Shanghai. πŸ₯ Currently, an Attending Urologist at Fudan University Shanghai Cancer Center, building on a comprehensive Residency experience from July 2018 to June 2021. 🌐 Actively engaged in groundbreaking research, exploring the mechanisms of SPOP-mediated non-degradable ubiquitination in prostate cancer. πŸ§ͺ Passionate about advancing understanding in the field and contributing to cutting-edge studies. πŸš€ Excited to leverage skills and knowledge for further advancements in urological oncology. #UrologyExpert #ResearchInnovator

🌐 Professional Profiles

πŸŽ“  Education & Training

Ph.D., Sep 2015 – Jun 2018 Research Interests: Urological oncology, Ubiquitination, Tumorigenesis Fudan University, Shanghai, China. State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P.R. China. M.D., Sep 2012 – Jun 2015 Research Interests: Urological oncology Fudan University, Shanghai, China

πŸ”¬  Researcher & Professional Experience

Residency at Fudan University Shanghai Cancer Center, July 2018-June 2021, Attending Urologist at Fudan University Shanghai Cancer Center, July 2021-

πŸ” Charge Topic Researcher

Study on the mechanism of SPOP-mediated non-degradable ubiquitination modification of ARHGAP29 in regulating the Hippo pathway in prostate cancer. Shanghai Sailing Program (Grant No. 19YF 1408600) Study on the mechanism of SPOP-mediated ZMYND8 non-degradable ubiquitin-modification in prostate cancer to regulate DNA damage response. Natural Science Foundation of China (Grant No. 81902614)

πŸ“šTop Noted Publication

 

  • Title: Unveiling the impact of tertiary lymphoid structures on immunotherapeutic responses of clear cell renal cell carcinoma
    • Authors: W. Xu, J. Lu, X. Tian, S. Ye, S. Wei, J. Wang, A. Anwaier, Y. Qu, W. Liu, K. Chang, H. Zhang, D. Ye
    • Journal: MedComm(2020), 5 (2024) e461
    • Co-correspondence, IF: 9.9

 

 

  • Title: Plasma proteomic profiling discovers molecular features associated with upper tract urothelial carcinoma
    • Authors: Y. Qu, Z. Yao, N. Xu, G. Shi, J. Su, S. Ye, K. Chang, K. Li, Y. Wang, S. Tan, X. Pei, Y. Chen, Z. Qin, J. Feng, J. Lv, J. Zhu, F. Ma, S. Tang, W. Xu, X. Tian, A. Anwaier, S. Tian, W. Xu, X. Wu, S. Zhu, Y. Zhu, D. Cao, M. Sun, H. Gan, J. Zhao, H. Zhang, D. Ye, C. Ding
    • Journal: Cell Rep Med, 4 (2023) 101166
    • Co-first, IF: 14.3

 

 

  • Title: The expression and prognostic value of transporter 1, ATP binding cassette subfamily B member in clear cell renal cell cancer with experimental validation
    • Authors: Z.D. Wang, X. Tian, Y. Wang, J.J. Wang, S.Q. Ye, Y.Q. Huang, Y.Y. Qu, K. Chang, G.H. Shi, D.W. Ye, C.Y. Gu
    • Journal: Front Oncol, 12 (2022) 1013790
    • Co-correspondence, IF: 5.738

 

  • Title: Construction of an Immune Escape-Related Signature in Clear Cell Renal Cell Carcinoma and Identification of the Relationship between IFNAR1 and Immune Infiltration by Multiple Immunohistochemistry
    • Authors: K. Chang, F. Xu, X. Zhang, B. Zeng, W. Zhang, G. Shi, D. Ye
    • Journal: Cancers (Basel), 15 (2022)
    • Co-first, IF: 6.575

 

 

  • Title: Development and validation of a mitochondrial metabolism-associated nomogram for prediction of prognosis in clear cell renal cell carcinoma
    • Authors: B. Zeng, Y. Huang, S. Jin, X. Zhang, H. Zhang, G. Shi, D. Cao, K. Chang, B. Dai, D. Ye
    • Journal: Clin Transl Med, 10 (2020) e120
    • Co-correspondence, IF: 7.919

 

Ramesh Pothuraju | Cancer Biology | Best Researcher Award

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Assist Prof Dr. Ramesh Pothuraju | Cancer Biology | Best Researcher Award

 

πŸ‘¨β€πŸ«Professional Profile 🌟

πŸ”¬ Accomplished Scientist with a strong research background, currently serving as Scientist C and Ramanujan Faculty Fellow at the prestigious Rajiv Gandhi Centre for Biotechnology in Kerala, India. Formerly, I held positions as an Instructor and Postdoctoral Fellow at the University of Nebraska Medical Center in the United States, showcasing my commitment to international research endeavors. My academic journey includes a Ph.D. from the National Dairy Research Institute in India, complemented by a wealth of teaching and research experience. Recognized with accolades such as the DST-Ramanujan re-entry fellowship and an Outstanding Poster Presentation Award, I am deeply passionate about Biochemistry, Molecular & Cell Biology, Immunology, and exploring diverse facets of health, including obesity and gastrointestinal health. πŸŒπŸ” #ScientificResearch #Biotechnology #Biochemistry #HealthScience

🌐 Professional Profiles

 

πŸ”¬ Research Experience

Scientist C Rajiv Gandhi Centre for Biotechnology, Kerala, India,(December 2023 – Present), Ramanujan Faculty Fellow Rajiv Gandhi Centre for Biotechnology, Kerala, India (July 2023 – December 2023) Instructor University of Nebraska Medical Center, Omaha, United States (February 2020 – April 2023 Postdoctoral Fellow University of Nebraska Medical Center, Omaha, United States (February 2016 – January 2020 Senior Research Fellow National Dairy Research Institute, Karnal, India (October 2015 – February 2016)

πŸŽ“ Education

Ph.D. (2015) National Dairy Research Institute, Karnal, India, M.S. (2009) National Dairy Research Institute, Karnal, India, B.S. (2004) Sri KrishnaDevaraya University, Anantapur, India

πŸ† Awards and Honors

2023 DST-Ramanujan Re-entry Fellowship (Awarded), 2022 Outstanding Poster Presentation Award at Biochemistry and Molecular Biology Symposium, University of Nebraska Medical Center, Omaha, USA, 2013 Qualified ICAR-ASRB, National Eligibility Test (NET), 2009 – 2013 Awarded Institutional Fellowship for doctoral studies at National Dairy Research Institute, India, 2006 – 2009 Awarded Institutional Fellowship for master studies at National Dairy Research Institute, India

πŸ“š Teaching and Research Interest

πŸ§ͺ Biochemistry, Molecular & Cell Biology, Immunology, Research techniques, Obesity, Functional foods, Prebiotics, Probiotics, Gut microbiota, Intestinal homeostasis, Mucin biology,  Irritable bowel diseases, Colorectal cancer, Transgenic mouse models for cancers

 

πŸ“šTop Noted Publication

Barkeer S*, Pothuraju R*, Malakar P, Pimental TC, Siddiqui JA. Nair SA.
Gum Acacia Dietary Fiber: Significance in Immunomodulation, Inflammatory Diseases and Cancer.
Phytotherapy Research, 2024, DOI: 10.1002/ptr.8125 (IF: 7.2).

 

Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Shanmugam M, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan J, Lorson CL, Watrelot AA, Foster JM, Mansel TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S.
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Int. J. Mol. Sci. 2024, 25(1), 539; doi.org/10.3390/ijms25010539 (IF: 5.6).

 

Sharma, T Sirpu Natesh N, Pothuraju R, Batra SK and Rachagani S.
Gut microbiota: a non-target victim of pesticide-induced toxicity.
Gut Microbes. 2023, 15(1):2187578. doi: 10.1080/19490976.2023.2187578 (IF: 12.2).

 

Sharma G, Sultana A, Abdullah KM, Pothuraju R, Nasser MW, Batra SK, Siddiqui JA.
Epigenetic regulation of bone remodeling and bone metastasis.
Semin Cell Dev Biol. 2022, S1084-9521(22)00294-4, doi: 10.1016/j.semcdb.2022.11.002 (IF: 7.3).

 

Pothuraju R, Pai P, Chaudhary S, Siddiqui JA, Cox JL, Kaur S, Rachagani S, Roy HK, Bouvet M and Batra SK.
Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer.
Aging. 2022, 14(5):2025-2046. doi: 10.18632/aging.203935 (IF: 5.2)
(Highlighted in front cover page).

 

Muniyan S, Pothuraju R, Seshacharyulu P and Batra SK.
Macrophage inhibitory cytokine-1 in cancer: Beyond the cellular phenotype.
Cancer Letters. 2022, doi.org/10/1016/j.canlet.2022.215664 (IF: 9.7).

 

Sharma G, Pothuraju R, Kanchan RK, Batra SK, Siddiqui JA.
Chemokines network in bone metastasis: Vital regulators of seeding and soiling.
Semin Cancer Biol. 2022, S1044-579X(22)00024-4, doi: 10.1016/j.semcancer.2022.02.003 (IF: 14.5).

 

Siddiqui JA, Seshacharyulu P, Muniyan S, Pothuraju R, Khan P, Vengoji, R, Chaudhary S, Maurya S, Lele S, Jain M, Datta K, Nasser MW, Batra SK.
GDF15 promotes prostate cancer bone metastasis and colonization through osteoblastic CCL2 and RANKL activation.
Bone Research, 2022. 10(1):6, doi.org/10.1038/s41413-021-00178-6 (IF: 12.7).

 

Siddiqui JA, Pothuraju R, Khan P, Sharma G, Muniyan S, Seshacharyulu P, Muniyan S, Jain M, Nasser MW, Batra SK.
Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia.
Cytokine & Growth Factor Reviews. 2021. 64:71-83, doi: 10.1016/j.cytogfr.2021.11.002 (IF: 13).

 

Athira S, Mann B, Sharma R, Pothuraju R, Bajaj RK.
Preparation and characterization of iron-chelating peptides from whey protein: An alternative approach for chemical iron fortification.
Food Research International, 2021, 141, 110133, doi.org/10.1016/j.foodres.2021.110133 (IF: 8.1)