Muthyam Sowjanya |Cancer | Women Researcher Award

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Dr. Muthyam Sowjanya | Cancer | Women Researcher Award

Dr at Vikrama simhapuri university,Ā  India

Sowjanya Muthyam, Ph.D., is a dedicated and highly skilled scientist with 8 years of expertise in immunology, inflammation, molecular biology, cell biology, and biochemistry. Having worked on diverse research projects, including promoting polythene degradation by Spingomonas bacteria and studying bioactive compound production from fungi, Dr. Muthyam seeks a Scientist position to advance industrial, clinical, and translational research.

Profile

Orcid

Education šŸŽ“

Dr. Muthyam holds a Ph.D. in Biotechnology from Andhra University (2014-2019), where her thesis focused on isolating, purifying, and characterizing novel anticancer compounds from Leucas indica flowers. She also completed her M.Sc. in Biotechnology from SRM University (2009-2011), where she studied shell loss in P. monodon and the antiglycation effects of spices. She holds a B.Sc. in Biotechnology, Chemistry, and Computer Applications from Sri Venkateswara University (2006-2009).

Research Experience šŸ’¼

Dr. Muthyam’s doctoral research involved isolating and characterizing bioactive compounds from Leucas indica, revealing an anticancer compound that inhibited cancer cell proliferation, particularly in MCF-7 and HeLa cell lines. Her work involved various techniques like column chromatography, UV, TLC, NMR, and apoptosis assays, contributing significantly to cancer treatment strategies. She also collaborated on projects related to bioremediation and bioactive compound production.

Awards šŸ†

Dr. Muthyam has received the UGC RGNF fellowship as a Junior Research Fellow (2014-2016) and a Senior Research Fellow (2016-2019). She has also mentored graduate and undergraduate students, supervised research projects, and served as a judge for research poster presentations. Her contributions to the field have earned recognition within the scientific community, particularly for her work on novel anticancer compounds.

Research Focus šŸ”

Dr. Muthyam’s primary research focuses on the isolation and characterization of bioactive compounds, with a strong emphasis on anticancer agents. Her work also explores bioremediation strategies, enzyme production, and the application of fungi in industrial processes. Dr. Muthyam is particularly interested in advancing molecular biology, immunology, and biochemistry to develop therapeutics for cancer treatment and environmental sustainability.

Teaching and Mentoring ExperiencešŸ§‘ā€šŸ«

Dr. Muthyam has a solid background in teaching and mentoring, having supervised over 40 graduate students and interns at Andhra University. She has also mentored numerous undergraduate students and evaluated their research poster presentations. Additionally, she is currently serving as a guest faculty member at Vikrama Simhapuri University, where she continues to guide students in research and development.

Conclusion šŸ“

Dr. Sowjanya Muthyam stands out as a promising researcher with a solid academic foundation, innovative research achievements, and a passion for mentoring the next generation of scientists. Her work, particularly in cancer treatment and bioactive compounds, holds immense potential for future clinical and industrial applications. By focusing on expanding her publication record, collaborations, and public engagement, she can significantly enhance her impact in the scientific community. Dr. Muthyam is a strong candidate for the Women Researcher Award, and her continued contributions will undoubtedly advance the fields of biotechnology and molecular medicine.

Publications šŸ“š

  1. Probiotics Contribution to the Development of Aquaculture: A Review
    • Journal: African Journal of Biological Sciences
    • Date: 2024-07-20
    • Contribution: Sowjanya Muthyam

 

  1. Immobilisation of Aspergillus flavus Strain S4 Spores for Optimal Production and Activity of L-Glutaminase
    • Journal: Chelonian Conservation and Biology
    • Date: 2023-11-11
    • Contribution: Sowjanya Muthyam

 

  1. Incidence of White Feces Syndrome (WFS) and Its Management with Herbal Supplements (Allium sativum and Curcuma longa) by Improving the Growth and Gut Health of Shrimp Litopenaeus vannamei (Boone-1931)
    • Journal: IJFANS International Journal of Food and Nutritional Sciences
    • Date: 2023-11-11
    • Contribution: Sowjanya Muthyam

 

  1. Industrial Applications of Alkaline Protease with Novel Properties from Bacillus cereus Strain S8
    • Date: 2023-11-07
    • Contribution: Sowjanya Muthyam

 

  1. Phytochemical Analysis and Antimicrobial Activity of Muntingia calabura
    • Journal: Journal of Chemical Health Risks
    • Date: 2023-11-07
    • Contribution: Sowjanya Muthyam

 

  1. Characterization of Alkaline Protease from Bacillus cereus Strain S8 by In Silico Approach
    • Journal: Chelonian Conservation and Biology
    • Date: 2023-11-02
    • Contribution: Sowjanya Muthyam

 

  1. In Vitro Antibacterial Activity of Flower Extract of Leucas indica
    • Journal: Journal of Advanced Zoology
    • Date: 2023-11-02
    • Contribution: Sowjanya Muthyam

 

  1. Antiglycation Effect of Chillies and Spices Used in Traditional Indian Cuisine
    • Journal: European Journal of Biomedical and Pharmaceutical Sciences
    • Date: 2023-10-22
    • Contribution: Sowjanya Muthyam

 

  1. Purification, Characterization Studies of L-Glutaminase from Aspergillus flavus Strain S4
    • Journal: Journal of Advanced Zoology
    • Date: 2023-10-01
    • Contribution: Sowjanya Muthyam

 

  1. Probiotics and Their Prolific Role in Shrimp Farming Practices
  • Date: 2022-12-26
  • Contribution: Sowjanya Muthyam

 

Angelika Długosz-Pokorska | cancer research | Women Researcher Award

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Ā Dr. Angelika Długosz-Pokorska | cancer research |Women Researcher Award

Ā Dr at Medical University of ÅĆ³dÅŗ,Ā  Poland

A dedicated researcher and project leader at the Medical University of Lodz, Poland, with expertise in pharmacological characterization and anticancer drug development. As Principal Investigator and Co-investigator, led projects funded by prestigious grants like OPUS and SONATA, focusing on opioid peptide analogs and alpha-methylidene-delta-lactones. Supervising international student exchanges and engaging in expert activities, workshops, and editorial work. Recognized with numerous awards for scientific excellence, including Rector’s Awards and IF=8.638 for publication series on opioid mimetics and glutathione peroxidase. Committed to advancing medical science through innovative research and academic leadership.

Profile

  1. Scopus

 

  1. Orcid

šŸ“œ Employment History:

Research Associate (2017-present) Medical University of Lodz, Poland; Faculty of Medicine. Co-investigator (2016-2021)
Project: Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple receptors
Grant: OPUS 9, project ID 2015/17/B/ST5/00153. Principal Investigator (2016-2021) Project: Analysis of the anticancer activity of new synthetic alpha-methylidene-delta-lactones in selected cell lines Grant: SONATA, project ID 2015/17/D/NZ3/02226. Supervisor, Project Manager, and Principal Investigator (2018-present) Project: Analysis of the anticancer activity and molecular mechanism of action of new hybrid molecules containing uracil skeleton with an exo-cyclic methylene group Grant: PRELUDIUM13, project ID UMO-2017/25/N/NZ3/01039

šŸ“š Short Research Training:

University of Rouen, France (2014) Laboratoire de Neuropsychopharmacologie ExpƩrimentale

šŸŒ Activities:

  • Expert Activity/Reviewer (2024)
    Platform: Qeios
  • International Student Exchanges and ERASMUS Supervision (2024)
    Engaging in initiatives and participating in European Union programs, overseeing ERASMUS students.
  • Participation in Scientific Workshops and Research Teams (2024)
    Engaging in workshops aimed at exchanging experiences, self-improvement, and organization.
  • Editorial Work (2023-present)
    Journal: Reviewer for Breast Cancer-Tokyo, ISSN 1340-6868, eISSN 1880-4233.

šŸ† Awards and Distinctions:

2022: First-level Special Award for Outstanding Didactic Work by Academic Teachers Medical University of Lodz.

2020: Team Distinction from the Faculty of Chemistry Nicolaus Copernicus University in Toruń Rector’s Award Medical University of Lodz Second-degree scientific award for a series of publications titled: ‘Investigation of the Anticancer Properties of Synthetic Analogues of Compounds Isolated from Plants’. (Impact Factor – 8.034). Polish Intelligent Development Award – Nomination.

2019: Investigation of Anticancer Activity of Synthetic Analogues of Methylenolactones”, IF=4.026PTBioch Bursary Scholarship 44th FEBS Congress “From Molecules to Living Systems”. Rector’s Award Medical University of Lodz Second Prize for Publication: ‘Synthetic Analogues of Coumarin as Novel Agents with Anticancer Activity’. (Impact Factor = 4.173). Rector’s Award Medical University of Lodz Team Second award for Publication Series:

2017: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Synthesis and Investigation of Biological Activity of Opioid Mimetics and Glutathione Peroxidase”. (IF=8.638). Rector’s Award Medical University of Lodz Team First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Dicoumarins”. (IF=6.221) “Investigation of Anticancer Activity of Sesquiterpene Lactones”. (IF=4.994)

2016: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Lactones in Combination with Known Anticancer Drugs”. (IF = 8.835)

Publications Top Notes šŸ“

  • Title: Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluation-Part I
    • Authors: Laskowska, A., Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., et al.
    • Journal: Materials
    • Year: 2024
    • Volume: 17
    • Pages: 1ā€“15
    • Summary: This study focuses on the synthesis of new chiral Ī²-carbonyl selenides and evaluates their antioxidant and anticancer activities, providing valuable insights into potential therapeutic agents.

 

  • Title: New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF7 Cancer Cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Biologics: Targets and Therapy
    • Year: 2023
    • Volume: 17
    • Pages: 69ā€“83
    • Summary: This article presents a novel uracil analog with potential to reverse resistance to Taxol in MCF7 cancer cells, indicating its promising role as an anticancer agent.

 

  • Title: New Uracil Analog- U-359 can Reverse Resistance to Taxol in MCF-7 cancer cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Acta Biochimica Polonica
    • Year: 2023
    • Volume: 70
    • Pages: 56
    • Summary: This study explores another uracil analog’s potential to reverse resistance to Taxol in MCF-7 cancer cells, indicating a promising avenue for further research.

 

  • Title: The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides
    • Authors: Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., Jastrzębska, A., et al.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Pages: 1ā€“11
    • Summary: This research investigates the impact of long carbon chains on the antioxidant and anticancer properties of N-substituted benzisoselenazolones and corresponding diselenides, providing valuable insights into structure-activity relationships.

 

  • Title: Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics
    • Authors: Laskowska, A., Pacuła-Miszewska, A., Długosz-Pokorska, A., et al.
    • Journal: Materials
    • Year: 2022
    • Volume: 16
    • Pages: 1ā€“14
    • Summary: This study explores the modification of GPx mimetics’ activity through the attachment of chiral functional groups, offering potential strategies for enhancing therapeutic effects.