Angelika Długosz-Pokorska | cancer research | Women Researcher Award

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 Dr. Angelika Długosz-Pokorska | cancer research |Women Researcher Award

 Dr at Medical University of Łódź,  Poland

A dedicated researcher and project leader at the Medical University of Lodz, Poland, with expertise in pharmacological characterization and anticancer drug development. As Principal Investigator and Co-investigator, led projects funded by prestigious grants like OPUS and SONATA, focusing on opioid peptide analogs and alpha-methylidene-delta-lactones. Supervising international student exchanges and engaging in expert activities, workshops, and editorial work. Recognized with numerous awards for scientific excellence, including Rector’s Awards and IF=8.638 for publication series on opioid mimetics and glutathione peroxidase. Committed to advancing medical science through innovative research and academic leadership.

Profile

  1. Scopus

 

  1. Orcid

📜 Employment History:

Research Associate (2017-present) Medical University of Lodz, Poland; Faculty of Medicine. Co-investigator (2016-2021)
Project: Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple receptors
Grant: OPUS 9, project ID 2015/17/B/ST5/00153. Principal Investigator (2016-2021) Project: Analysis of the anticancer activity of new synthetic alpha-methylidene-delta-lactones in selected cell lines Grant: SONATA, project ID 2015/17/D/NZ3/02226. Supervisor, Project Manager, and Principal Investigator (2018-present) Project: Analysis of the anticancer activity and molecular mechanism of action of new hybrid molecules containing uracil skeleton with an exo-cyclic methylene group Grant: PRELUDIUM13, project ID UMO-2017/25/N/NZ3/01039

📚 Short Research Training:

University of Rouen, France (2014) Laboratoire de Neuropsychopharmacologie Expérimentale

🌍 Activities:

  • Expert Activity/Reviewer (2024)
    Platform: Qeios
  • International Student Exchanges and ERASMUS Supervision (2024)
    Engaging in initiatives and participating in European Union programs, overseeing ERASMUS students.
  • Participation in Scientific Workshops and Research Teams (2024)
    Engaging in workshops aimed at exchanging experiences, self-improvement, and organization.
  • Editorial Work (2023-present)
    Journal: Reviewer for Breast Cancer-Tokyo, ISSN 1340-6868, eISSN 1880-4233.

🏆 Awards and Distinctions:

2022: First-level Special Award for Outstanding Didactic Work by Academic Teachers Medical University of Lodz.

2020: Team Distinction from the Faculty of Chemistry Nicolaus Copernicus University in Toruń Rector’s Award Medical University of Lodz Second-degree scientific award for a series of publications titled: ‘Investigation of the Anticancer Properties of Synthetic Analogues of Compounds Isolated from Plants’. (Impact Factor – 8.034). Polish Intelligent Development Award – Nomination.

2019: Investigation of Anticancer Activity of Synthetic Analogues of Methylenolactones”, IF=4.026PTBioch Bursary Scholarship 44th FEBS Congress “From Molecules to Living Systems”. Rector’s Award Medical University of Lodz Second Prize for Publication: ‘Synthetic Analogues of Coumarin as Novel Agents with Anticancer Activity’. (Impact Factor = 4.173). Rector’s Award Medical University of Lodz Team Second award for Publication Series:

2017: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Synthesis and Investigation of Biological Activity of Opioid Mimetics and Glutathione Peroxidase”. (IF=8.638). Rector’s Award Medical University of Lodz Team First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Dicoumarins”. (IF=6.221) “Investigation of Anticancer Activity of Sesquiterpene Lactones”. (IF=4.994)

2016: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Lactones in Combination with Known Anticancer Drugs”. (IF = 8.835)

Publications Top Notes 📝

  • Title: Synthesis of New Chiral β-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluation-Part I
    • Authors: Laskowska, A., Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., et al.
    • Journal: Materials
    • Year: 2024
    • Volume: 17
    • Pages: 1–15
    • Summary: This study focuses on the synthesis of new chiral β-carbonyl selenides and evaluates their antioxidant and anticancer activities, providing valuable insights into potential therapeutic agents.

 

  • Title: New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF7 Cancer Cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Biologics: Targets and Therapy
    • Year: 2023
    • Volume: 17
    • Pages: 69–83
    • Summary: This article presents a novel uracil analog with potential to reverse resistance to Taxol in MCF7 cancer cells, indicating its promising role as an anticancer agent.

 

  • Title: New Uracil Analog- U-359 can Reverse Resistance to Taxol in MCF-7 cancer cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Acta Biochimica Polonica
    • Year: 2023
    • Volume: 70
    • Pages: 56
    • Summary: This study explores another uracil analog’s potential to reverse resistance to Taxol in MCF-7 cancer cells, indicating a promising avenue for further research.

 

  • Title: The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides
    • Authors: Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., Jastrzębska, A., et al.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Pages: 1–11
    • Summary: This research investigates the impact of long carbon chains on the antioxidant and anticancer properties of N-substituted benzisoselenazolones and corresponding diselenides, providing valuable insights into structure-activity relationships.

 

  • Title: Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics
    • Authors: Laskowska, A., Pacuła-Miszewska, A., Długosz-Pokorska, A., et al.
    • Journal: Materials
    • Year: 2022
    • Volume: 16
    • Pages: 1–14
    • Summary: This study explores the modification of GPx mimetics’ activity through the attachment of chiral functional groups, offering potential strategies for enhancing therapeutic effects.

 

Teng Zhang | Gynecologic Oncology | Young Scientist Award

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Ms. ‌Teng Zhang |Gynecologic Oncology |Young Scientist Award 

Ms at Qilu Hospital of Shandong University, China

Ms. Teng Zhang is an accomplished Attending Doctor in the Department of Obstetrics and Gynecology at Qilu Hospital of Shandong University. With a Ph.D. and Master’s degree from Cheeloo College of Medicine, Shandong University, and a Bachelor’s degree from Jining Medical College, Ms. Zhang has extensive experience in clinical practice and research. Notable achievements include publications on cervical cancer in high-impact journals and awards in English teaching competitions. Dr. Zhang’s research focuses on fertility-sparing treatments, m6A methylation, and immune cell variations in cervical cancer, underscoring a strong commitment to advancing women’s health.

Profile

 

🎓 Education Background

Sept. 2015 – Sep. 2018: Ph.D., Cheeloo College of Medicine, Shandong University. Sept. 2013 – Sep. 2015: Master, Cheeloo College of Medicine, Shandong University. Sept. 2008 – Jun. 2013: Bachelor of Medicine, Jining Medical College. Sept. 2005 – Jun. 2008: Qingdao No.2 Middle School

💼 Research/Work Experience

July 2022 – Present: Attending Doctor, Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University. Nov. 2018 – June 2021: Resident, Department of Gynecology and Obstetrics, Qilu Hospital of Shandong University. June 2016 – June 2017: Visiting Scholar, Griffith University, Australia

🏆 Scholarships and Awards

2023: Young Teachers English Teaching Competition, Second Prize, Cheeloo College of Medicine, Shandong University, 2021: The First “Guangzhi Cup” English Teaching Competition in Qilu Hospital of Shandong University, Third Prize, July 2013: Excellent Graduate of Shandong Province, Oct. 2009: National Scholarship

Publications Top Notes 📝

  • Xuji Jiang, Chuanli Feng, Wanying Sun, Teng Zhang*, Baoxia Cui. “The top 100 most cited articles on fertility-sparing treatments for cervical cancer: A bibliometric analysis.” Heliyon, 10(11), 2024.

 

  • Zhonghao Mao, Bingyu Wang, Teng Zhang, Baoxia Cui*. “The roles of m6A methylation in cervical cancer: functions, molecular mechanisms, and clinical applications.” Cell Death and Disease, 2023, 14(734).

 

  • Teng Zhang, Jun Jiao, Xinlin Jiao, Lu Zhao, Xinli Tian, Qing Zhang, Daoxin Ma, Baoxia Cui*. “Aberrant frequency of TNFR2+ Treg and related cytokines in patients with CIN and cervical cancer.” Oncotarget, 2017, 9(4).

 

  • Bingyu Wang, Zhonghao Mao, Jinwen Ye, Xinlin Jiao, Teng Zhang, Qi Wang, Sai Han, Youzhong Zhang, Chunling Wang, Taotao Dong, Baoxia Cui. “Glycolysis Induced by METTL14 Is Essential for Macrophage Phagocytosis and Phenotype in Cervical Cancer.” The Journal of Immunology, 2024, 15(212).

 

  • Zhang W, Tian X, Mumtahana F, Jiao J, Zhang T, Croce K.D., Cui B*. “The existence of Th22, pure Th17 and Th1 cells in CIN and Cervical Cancer along with their frequency variation in different stages of cervical cancer.” BMC Cancer, 2015, 15,717.

 

  • Jun Jiao, Teng Zhang, Xinlin Jiao, Tingting Huang, Lu Zhao, Daoxin Ma, Baoxia Cui*. “hsa_circ_0000745 promotes cervical cancer by increasing cell proliferation, migration, and invasion.” J Cell Physiol, 2019, 1-9.

 

  • Xinlin Jiao, Siying Zhang, Jun Jiao, Teng Zhang, Wenjie Qu, Guy Mutangala Muloye, Beihua Kong, Qing Zhang, Baoxia Cui*. “Promoter methylation of SEPT9 as a potential biomarker for early detection of cervical cancer and its overexpression predicts radioresistance.” Clin Epigenetics, 2019, 11(120).

 

 

Mohammad Khosravi | Immunotherapy | Excellence in Innovation

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Assoc Prof Dr. Mohammad Khosravi | Immunotherapy | Excellence in Innovation

Assoc Prof Dr. Shahid Chamran University of Ahvaz Iran

👩‍🔬 A highly skilled immunologist and veterinarian with a Ph.D. from Tehran University, specializing in molecular characterization and immunology techniques. Experienced in cell culture, gene characterization, protein analysis, and chromatography. Proficient in serology techniques, immunization, and animal handling. Skilled in bioinformatics analysis and extensive knowledge of SPSS and Microsoft Office Suite. Adept at teaching fundamental and advanced immunology to both D.V.M. and Ph.D. students. Demonstrated expertise in avian immunology and diagnostic techniques. Accomplished in research and teaching, contributing significantly to the field of immunology and veterinary medicine.🌟

 

Profile

Scopus

 

Education 📚

PhD in Immunology: Tehran University, Tehran, Iran, 2013.Thesis: Molecular characterization of chicken class II transactivator gene.DVM (Doctor of Veterinary Medicine): Shahrekord University, Chaharmahal bakhteyari, Iran, 2007.Thesis: A comparison of ELISA and histopathology for the detection of paratuberculosis in dairy cattle.

Research Experience and Technical Skills 🔬

Cell culture (primary and immortalized cell lines).Stem cell isolation technique.Isolation of leukocyte subsets.Purification of antibody subsets.Gene characterization: PCR, RT-PCR, QRT-PCR, Real Time-PCR, Gene cloning, Bioinformatics analysis.Protein and Oligosaccharide SDS-PAGE.Western blotting.Serology techniques: ELISA, Agglutination, Precipitation, Hemagglutination.Chromatographic techniques: Affinity, Ion-exchange, Gel-filtration.Purification of protein and carbohydrate.Immunization techniques.Animal handling.Extensive experience of SPSS, Microsoft Word, Excel, PowerPoint.Hapten immunization (Preparation of the hyper immune sera against drugs and metals).Synthesis of the metal nanoparticles (Fe, Cu, Au, Zn).Synthesis of the immunomagnetic beads for separation of the microorganisms, cells, drugs, and metals.Synthesis of the latex agglutination beads for detection of the cells, drugs, and metals.

Teaching Experience (2013-2022) 📖

At Shahid Chamran University of Ahvaz, Khuzestan, Iran:

  • Fundamental Immunology for D.V.M students.
  • Advanced Immunology for Ph.D students of bacteriology.
  • Serology Technique for D.V.M students.
  • Avian Immunology for PhD students of poultry hygiene and diseases.
  • Diagnostic Immunology for Ph.D students of clinical pathology.

Publications Top Notes 📝

  1. Title: Quorum quenching probiotics modulated digestive enzymes activity, growth performance, gut microflora, haemato-biochemical parameters and resistance against Vibrio harveyi
    • Authors: R Ghanei-Motlagh, T Mohammadian, D Gharibi, M Khosravi, E Mahmoudi, …
    • Journal: Aquaculture
    • Volume: 531
    • Pages: 735874
    • Year: 2021

 

  1. Title: Quorum Quenching Properties and Probiotic Potentials of Intestinal Associated Bacteria in Asian Sea Bass Lates calcarifer
    • Authors: R Ghanei-Motlagh, T Mohammadian, D Gharibi, S Menanteau-Ledouble, …
    • Journal: Marine drugs
    • Volume: 18
    • Issue: 1
    • Pages: 23
    • Year: 2019

 

  1. Title: Feed supplementation with quorum quenching probiotics with anti-virulence potential improved innate immune responses, antioxidant capacity and disease resistance in Asian …
    • Authors: R Ghanei-Motlagh, D Gharibi, T Mohammadian, M Khosravi, E Mahmoudi, …
    • Journal: Aquaculture
    • Volume: 535
    • Pages: 736345
    • Year: 2021

 

  1. Title: Antibacterial effects of Aloe vera extracts on some human and animal bacterial pathogens
    • Authors: D Gharibi, M Khosravi, Z Hosseini, F Boroun, SK Barzgar, A Forughi Far
    • Journal: Journal of Medical Microbiology and Infectious Diseases
    • Volume: 3
    • Issue: 1
    • Pages: 6-10
    • Year: 2015