Elshimaa Abdelhafez | Medicinal Chemistry | Best Researcher Award

Published on by Young Scientists Awards

Dr. Elshimaa Abdelhafez | Medicinal Chemistry |Best Researcher Award

👨‍🏫Profile Summary

Elshimaa Abdelhafez is an accomplished academician with a strong background in Medicinal Chemistry. Holding a PhD from Minia University, Egypt, earned through the CHANNEL Program with Wake Forest University, USA, their research focuses on the synthesis, molecular modeling, and anticancer activity of organic compounds. With teaching experience since 2002, they have excelled as an Assistant Professor at Minia University, imparting knowledge in Medicinal and Organic Chemistry to undergraduate and postgraduate students. Their research experience spans mechanistic studies, chromatographic techniques, and computer-based drug design. Proficient in Arabic and English,Elshimaa Abdelhafez possesses excellent computer skills, making significant contributions to both academia and research.

🌐 Professional Profiles

Academic Qualifications 🎓:

PhD Degree, Pharmaceutical Sciences (Medicinal Chemistry), December 2013, Minia University (Minia, Egypt) (Earned through CHANNEL Program between the School of Art and Science, Chemistry Dep., Wake Forest University, NC, USA, and Faculty of Pharmacy, El-Minia University) Thesis Advisor: Prof. Dr. Bruce King, Prof. of Chemistry, Wake Forest University, NC, USA Thesis entitled “Synthesis, Molecular Modeling and Anticancer Activity of New Reserpine Derivatives as Inducers of Mis-Match Repair Protein” Master Degree: in Pharmaceutical Sciences (Medicinal Chemistry), January 2008, Faculty of Pharmacy, Minia University (Minia, Egypt) Thesis Advisor: Prof. Dr. Hassan H. A, Farag, Prof. of Pharmaceutical Chemistry, former dean, Faculty of Pharmacy, Assiut University. Thesis entitled: “Synthesis and Investigation of Certain Derivatives Pyrazole-3-Carboxylic Acid as Novel Carriers for Nitric Oxide” B.Sc Degree: In Pharmaceutical Sciences, May 2002, Faculty of Pharmacy, El-Minia University Grade: Excellent with honor (88.23%)

Professional Positions 👩‍🏫:

September 2002-December 2007: Teaching Assistant (demonstrator) at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. January 2008-May 2011: Assistant Lecturer at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. June 2011-June 2013: Research scholar at Prof. S. Bruce King Lab, Wake Forest University, Winston Salem, North Carolina, USA. June 2013-November 2013: Assistant Lecturer at Medicinal Chemistry department, Faculty of Pharmacy, Minia University. December 2013-Current: Assistant Professor at Medicinal Chemistry department, Faculty of Pharmacy, Minia University.

Research Experiences 🧪:

Channel scholarship at Chemistry Department, Prof. Dr. Bruce King laboratory Wake Forest University, North Carolina, USA (June 2011-June 2013) Design and synthesis of organic compounds of potential biological activities Reaction mechanistic study Chromatographic techniques (Flash chromatography, Column Chromatography, and Preparative chromatography). Biological study of the synthesized compounds by the help of other institutions. Prodrug approaches as a tool for enhancing drug properties Structural elucidation of various groups of synthesized products using spectroscopic techniques including IR, NMR (ID and 2D), elemental analysis and MS (HRMS and ESI). Computer-based drug design including the pharmacophore and structure-based designs using MOE version 2014. Postgraduate research student (master and doctoral student), Faculty of Pharmacy, Minia University, Minia, Egypt (October 2002-May 2011) Synthesis of NO releasing compounds using different synthetic and separation technique for NO release measurement Some biological testing like anti-inflammatory and ulcerogenicity Principles of drug design software Good teaching experience for both organic and medicinal chemistry.

Teaching Experience 📚:

Medicinal Chemistry Department, Faculty of Pharmacy, Minia University. Lecturer of Medicinal Chemistry (December 2013-current) Teaching theoretical Medicinal Chemistry courses for undergraduate pharmacy students (ANS, CNS, CVS, Drug Design, ….) Teaching theoretical Organic Chemistry courses for undergraduate pharmacy students (stereochemistry, spectroscopy, carboxylic acid & derivatives, heterocyclic chemistry, ..) Teaching Organic Spectroscopy for postgraduate pharmacy students (IR, NMR, Mass) Teaching Stereochemistry for clinical Pharmacy students. Teaching Advanced Medicinal Chemistry Course for postgraduate pharmacy students in Master degree of medicinal chemistry (special courses). Teaching Advanced Organic Chemistry Course for postgraduate pharmacy students in Master degree of medicinal chemistry(Special course). Organic Chemistry Department, Faculty of Pharmacy, Deraya University. Lecturer of Organic Chemistry (September 2015-Jan 2019) Teaching Organic Chemistry I & II courses for undergraduate pharmacy students (Introduction, stereochemistry, Heterocyclic Chemistry, Aromatic compounds, ….) Medicinal Chemistry Department, Faculty of Pharmacy, Minia University. Teaching Assistant. (September 2002-December 2013) Teaching practical Organic Chemistry courses. Teaching practical Medicinal Chemistry courses.

Skills 🌐:

  • Languages:
    • Arabic: mother tongue.
    • English: Excellent written and spoken)
  • Computer:
    • Excellent in windows, Word, PowerPoint, Internet, and Endnote
    • Very good in Excel and GraphPad Prism
    • (Passed ICDL exams – advanced ICTP, course exam)

 

📚Top Noted Publication

  1. M.G.A. Abd Elhalim, et al.
    • Title: Hemorrhoidectomy versus Hemorrhoidectomy with Internal Anal Sphincterotomy in Management of Hemorrhoids.

 

  1. S. Abdel Hafez, et al.
    • Title: The role of mast cells in accelerating our skin aging.

 

  1. E.-S.M. Abdel-Hafez, et al.
    • Title: Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide.

 

  1. A.M. Abdel-Hakem, E.-S.M. Abdelhafez, et al.
    • Title: Docking Studies Of Some E-2-Phenyl-4-(2-Phenylhydrazineylidene) Oxazol-5 (4H)-One Derivatives As A Potential Caspase-8 Inhibitor.

 

  1. E. Abdelhafez, et al.
    • Title: Comparing Open Preperitoneal Versus Laparoscopic Totally Extra Peritoneal Repair of Inguinal Hernia.

 

  1. E.-S.M.N. Abdelhafez, et al.
    • Title: Apoptotic inhibitors as therapeutic targets for cell survival.

 

  1. E.-S.M. AbdelHafez, et al.
    • Title: Synthesis, Molecular Modeling and Anticancer Activity of New Rescinnamine Derivatives as MMR-Inducers.

 

  1. E.M. AbdelHafez, et al.
    • Title: Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment.

 

  1. E.M. AbdelHafez, et al.
    • Title: Improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment.

 

  1. E.M.N. Abdelhafez, et al.
    • Title: Antimicrobial Activity of New Amide/thioamides Derivatives of Ciprofloxacin.

 

  1. E.S.M. AbdelHafez, et al.
    • Title: Lossen rearrangements under Heck reaction conditions.

 

  1. A.M. AbdelHakem, E.-S.M. Abdelhafez, et al.
    • Title: Current trends and future perspectives of antimutagenic agents.

 

  1. M. Abdullah, et al.
    • Title: Fluoroquinolones as urease inhibitors: anti-Proteus mirabilis activity and molecular docking studies.

Ahmed Abu-Dief | Medicinal chemistry| Best Scholar Award

Published on by Young Scientists Awards

 Prof Dr. Ahmed Abu-Dief | Medicinal chemistry| Best Scholar Award

 

👨‍🏫 🧪📚 Ahmed Mohammed Abu-Dief Mohammed, a distinguished researcher and educator, boasts a rich academic journey with a B.Sc. in Special Chemistry, M.Sc., and Ph.D. from Sohag University, Egypt. With a prolific h-index, his expertise in inorganic and physical chemistry spans diverse areas. His significant postdoctoral stints in Spain underscore a global perspective. Proficient in a myriad of computer skills,  Abu-Dief is not only a researcher but also an adept trainer. Awarded for his research and teaching contributions, he stands among the top scientists globally. His multifaceted skills, from synthesizing nanomaterials to designing nano photo catalysts, showcase a commitment to cutting-edge research. 🌐🏆 #Chemistry #Researcher #Education

🌐 Professional Profiles

🎓Education

BSc in Science Part of Special Chemistry (2004) Honors: Excellent with honor degree Centenary Rate: 85.99% MSc in Chemistry, Sohag University, Egypt (2010) Thesis: “Solvent and Temperature Effects on the Kinetic of Reactions and Their Reactivity Trends of Some Coumarin Derivatives” PhD in Chemistry, Sohag University, Egypt (2013) Thesis: “Design, Physicochemical Studies, Interaction with DNA, and Kinetic Investigation of The Reactivity of Some Multifunctional Complexes Containing Schiff Bases

🌐Postdoctoral Experience& Skills and Experiences

6 years postdoctorate in Inorganic Chemistry, Faculty of Chemistry, Barcelona University, Spain 10 years postdoctorate in Physical Chemistry, Department of Chemistry, Oviedo University, Spain Inorganic and Physical Chemistry Complex preparation and characterization (UV-Visible spectra, IR, NMR, CHN, conductance, thermal analysis) Magnetic properties of complexes Bonding in transition metal complexes and crystal field theory Kinetics and reactivity trends of indicator and laser dye compounds Thermodynamic and transfer properties of ions Kinetics of DNA interaction with coordination compounds Design and formation of single crystals of multifunctional systems Computer Skills Operating systems and program packages for Microsoft International Computer Driving License (ICDL) Training in statistical program (SPSS) and Photoshop Oracle Database and SQL expertise Experience in GC tool for catalytic reactions Synthesis of nanomaterials via hydrothermal method

🔬Research Experience and Interests

Study of base-catalyzed hydrolysis of Chromen-2-one derivatives Analysis of solvent effects on reactivity trends of coumarin derivatives Determination of thermodynamic properties of ions Design and characterization of Schiff base-amino acid complexes Investigation of multifunctional systems containing Schiff base ligands and 4f metals Synthesis and functionalization of nanoparticles for various applications

🏅Awards and Recognitions, Grade and Appreciation Certificates

Multiple awards for research excellence and contributions to academia, Top 2% of the world’s scientists (Stanford University classification, 2020-2023), International gold medal for outstanding performance in a project, Best Researcher Award in International Scientist Awards on Engineering, Science, and Medicine (2021), State Encouragement Award from the Academy of Scientific Research (2022), Certificates of thanks and appreciation for various contributions to academia, research, and training, Recognition for website management and teaching assistance, Active participation in international conferences and workshops

🔍Research Projects

Design and study of multifunctional systems containing Schiff bases,curcuminoid ligands and 4f metals towards the development of nano devices”2011-2012, AECID, program 7-PCI-EGIPTE (AP/040924/ 11) BarcelonaUniversity, Spain.o Mesoporous materials, 2014-2016,Spanish Ministerio de Economía yCompetitividad (MAT2013-40950-R), Gobierno del Principado de Asturias(GRUPIN14-060) and EDRF funding, Oviedo Universityo Solubility studies and Transfer Chemical Potentials in different organic cosolvent -water mixtures of Cobalt (III)-hydrazone complexes as Antimicrobialand anticancer agents, Grant No. 7679-SCI-2018-3-9-F from the Deanship ofScientific Research at Northern Border University, Arar, K.S.A.o Temperature and salt effects of the Kinetic reactions of substituted 2-pyridylmethylene-8-quinolyl iron (II) complexes as antimicrobial and anti-canceragents with Cyanide ions, Grant No. 1125-SCI-2019-1-10-F from the Deanship ofScientific Research at Northern Border University, Arar, K.S.A.o Eco-friendly synthesis of AgNPs using Delonix regia extract, characterizationand their applications as anticancer and antimicrobial agents, King SaudUniversity, Riyadh, Saudi Arabia Grant No. RSP-2020/79)o Synthesis of Erbium Oxide Supported on Cupper and Tungsten Oxides andTheir Nanocomposites with Polymers for Environmental and EnergyApplications, Sohag University, Egypt, 2019-2020 .

📚Top Noted Publication

A review on versatile applications of transition metal complexes incorporating Schiff bases Paper Published in 2015 Cited by 720

Metal based pharmacologically active agents: Synthesis, structural characterization, molecular modeling, CT-DNA binding studies and in vitro antimicrobial screening of iron (II …Paper Published in 2014 Cited by 215

Some new nano-sized Fe (II), Cd (II) and Zn (II) Schiff base complexes as precursor for metal oxides: Sonochemical synthesis, characterization, DNA interaction, in vitro …Paper Published in 2016 Cited by 211

Synthesis, characterization, DFT calculations and biological studies of Mn (II), Fe (II), Co (II) and Cd (II) complexes based on a tetradentate ONNO donor Schiff base ligand Paper Published in 2017 Cited by 179

Design, characterization, teratogenicity testing, antibacterial, antifungal and DNA interaction of few high spin Fe (II) Schiff base amino acid complexes Paper Published in 2017 Cited by 171

Sonochemical synthesis, DNA binding, antimicrobial evaluation and in vitro anticancer activity of three new nano-sized Cu (II), Co (II) and Ni (II) chelates based on tri … Paper Published in 2016 Cited by 167

Development and functionalization of magnetic nanoparticles as powerful and green catalysts for organic synthesis Paper Published in 2018 Cited by 158

Ni (II) and Cu (II) complexes with ONNO asymmetric tetradentate Schiff base ligand: synthesis, spectroscopic characterization, theoretical calculations, DNA interaction and …  Paper Published in 2017 Cited by 157

Tailoring, physicochemical characterization, antibacterial and DNA binding mode studies of Cu (II) Schiff bases amino acid bioactive agents incorporating 5-bromo-2 … Paper Published in 2015 Cited by 154