Virginia M. Concato-Lopes | drug-discovery | Best Researcher Award

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Dr. Virginia M. Concato-Lopes | toxicology Award |Best Researcher Award

👨‍🏫Profile Summary

With a Ph.D. and Master’s in Experimental Pathology from Universidade Estadual de Londrina, Brazil, and ongoing postdoctoral research at Cedars-Sinai Medical Center, I specialize in the biogenesis of large oncosomes. My academic journey includes a Bachelor’s in Biomedicine from Universidade do Norte do Paraná. I’ve provided academic advisory for research projects investigating the antiproliferative properties of oregano essential oil in cancer cells. Passionate about advancing biomedical knowledge, I contribute to cutting-edge research and mentorship initiatives. For further information, please refer to my published papers or contact the respective academic institutions directly.

🌐 Professional Profiles

🎓 Education

Postdoctoral Fellow in Biogenesis of Large Oncosomes Cedars-Sinai Medical Center, Los Angeles, California, United States (2023 – Current), Ph.D. in Experimental Pathology Universidade Estadual de Londrina, Londrina, Paraná, Brazil (2019 – 2023), Master in Experimental Pathology
Universidade Estadual de Londrina, Londrina, Paraná, Brazil (2017 – 2019) Bachelor of Biomedicine Universidade do Norte do Paraná, Paraná, Brazil (2013 – 2016).

👨‍🏫Academic Advisory

Milena Cremer de Souza: Evaluating the antiproliferative capacity of Oregano Essential Oil (Origanum vulgare) on PC-3 prostate cancer cells. (2022) Degree: Ciências Biológicas (Biological Sciences) Institution: Universidade Estadual do Norte do Paraná Funding: Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Maria Beatriz Madureira: Exploring the antiproliferative activity of oregano oil in liver carcinoma tumor lines. (2021) Degree: Biomedicine Institution: Philadelphia University Center  For further details, please refer to the respective academic papers or contact the institutions directly.

Published article (first author publication)

  1. Concato-Lopes, V. M., Gonçalves-Lens, M. D., Tomiotto-Pellissier, F., Detoni, M. B., Cruz, E. M. S., Bortoleti, B. T. D. S., Carloto, A. C. M., Rodrigues, A. C. J., Silva, T. F., Siqueira, E. D. S., De Matos, R. L. N., Alves Cardoso, I. L., Conchon-Costa, I., Lazarin-Bidoia, D., Arakawa, N. S., Dekker, R. F., Mantovani, M. S., & Pavanelli, W. R. Trilobolide-6-O-isobutyrate from Sphagneticola trilobata acts by inducing oxidative stress, metabolic changes and apoptosis-like processes by caspase 3/7 activation of human lung cancer cell lines. Phytomedicine, v. 155536, 2024.
  1. Concato-Lopes, V. M., Silva, T. F., Detoni, M. B., Cruz, E. M. S., Gonçalves, M. D., Da Silva Bortoleti, B. T., Tomiotto-Pellissier, F., Carloto, A. C. M., Madureira, M. B., Rodrigues, A. C. J., Schirmann, J. G., Barbosa-Dekker, A. M., Dekker, R. F., Conchon-Costa, I., Panis, C., Lazarin-Bidóia, D., Miranda-Sapla, M. M., Mantovani, M. S., & Pavanelli, W. R. 3,3′,5,5′-Tetramethoxybiphenyl-4,4’diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line. Biomedicine & Pharmacotherapy, 170, 115979, 2024.
  1. Concato, Virginia Marcia; Tomiotto-Pellissier, Fernanda; Silva, Taylon Felipe; Gonçalves, Manoela Daiele; Da Silva Bortoleti, Bruna Taciane; Detoni, Mariana Barbosa; Da Silva Siqueira, Elaine; Jacob Rodrigues, Ana Carolina; Schirmann, Jéseka Gabriela; De Melo Barbosa-Dekker, Aneli; Costa, Idessania Nazareth; Conchon-Costa, Ivete; Miranda-Sapla, Milena Menegazzo; Mantovani, Mario Sergio; Pavanelli, Wander Rogério. 3,3-,5,5–tetramethoxybiphenyl-4,4-diol induces cell cycle arrest in G2/M phase and apoptosis in human non-small cell lung cancer A549-cells. Chemico-Biological Interactions, v. 2020, p. 109133, 2020.

 

Published book chapters

  1. Silva, T. F.; Tomiotto-Pellissier, F.; Sanfelice, Raquel Arruda; Gonçalves, Manoela Daiele; Bortoleti, Bruna; Detoni, Mariana Barbosa; Rodrigues, Ana Carolina Jacob; Carloto, Amanda; Concato, Virginia Marcia; Siqueira, Elaine Da Silva; Costa, I. N.; Pavanelli, Wander; Conchon-Costa, Ivete; Miranda-Sapla, M. M. A 21st Century Evil: Immunopathology and New Therapies of COVID-19 In: CORONAVIRUS DISEASE (COVID-19): PATHOPHYSIOLOGY, EPIDEMIOLOGY, CLINICAL MANAGEMENT AND PUBLIC HEALTH RESPONSE.1 ed.Lausanne: Frontiers Media SA, 2023, v.C, p. 164-194.

 

  1. Fagundes, Tatiane Renata; Kawassaki, A. C. B.; Concato, Virginia Marcia; Assolini, João Paulo; Silva, Taylon Felipe; Goncalves, M. D.; Da Silva Siqueira, Elaine; Sahd, C. S.; Inoue, Fabricio Seidy Ribeiro; Silva, T. P.; Lima, D. M.; Ferreira, Mariane Okamoto; Conchon-Costa, Ivete; Pavanelli, W. R.; Panis, Carolina. Impact of Pesticides on Immune-Endocrine Disorders and Its Relationship to Cancer Development In: Handbook of Cancer and Immunology.30, 2023, p. 1-30.

 

  1. Tomiotto-Pellissier, Fernanda; Gonçalves, Manoela Daiele; Silva, Taylon Felipe; Concato, Virgínia Márcia; Bortoleti, Bruna Taciane da Silva; Arakawa, Nilton Syogo; Conchon-Costa, Ivete; Pavanelli, Wander Rogério; and Panis, Carolina. Structure-Activity Relationship (SAR) Studies on Anti-Cancer Bioactive Natural Products. In: Atta-ur-Rahman. Studies in Natural Products Chemistry. Netherlands: Elsevier. Volume 72, 1st edition, 2022. ISBN: 978-0-128-23944-5.

Published book chapters

  1. Silva, T. F.; Tomiotto-Pellissier, F.; Sanfelice, Raquel Arruda; Gonçalves, Manoela Daiele; Bortoleti, Bruna; Detoni, Mariana Barbosa; Rodrigues, Ana Carolina Jacob; Carloto, Amanda; Concato, Virginia Marcia; Siqueira, Elaine Da Silva; Costa, I. N.; Pavanelli, Wander; Conchon-Costa, Ivete; Miranda-Sapla, M. M. A 21st Century Evil: Immunopathology and New Therapies of COVID-19 In: CORONAVIRUS DISEASE (COVID-19): PATHOPHYSIOLOGY, EPIDEMIOLOGY, CLINICAL MANAGEMENT AND PUBLIC HEALTH RESPONSE.1 ed.Lausanne: Frontiers Media SA, 2023, v.C, p. 164-194.

 

  1. Fagundes, Tatiane Renata; Kawassaki, A. C. B.; Concato, Virginia Marcia; Assolini, João Paulo; Silva, Taylon Felipe; Goncalves, M. D.; Da Silva Siqueira, Elaine; Sahd, C. S.; Inoue, Fabricio Seidy Ribeiro; Silva, T. P.; Lima, D. M.; Ferreira, Mariane Okamoto; Conchon-Costa, Ivete; Pavanelli, W. R.; Panis, Carolina. Impact of Pesticides on Immune-Endocrine Disorders and Its Relationship to Cancer Development In: Handbook of Cancer and Immunology.30, 2023, p. 1-30.

 

  1. Tomiotto-Pellissier, Fernanda; Gonçalves, Manoela Daiele; Silva, Taylon Felipe; Concato, Virgínia Márcia; Bortoleti, Bruna Taciane da Silva; Arakawa, Nilton Syogo; Conchon-Costa, Ivete; Pavanelli, Wander Rogério; and Panis, Carolina. Structure-Activity Relationship (SAR) Studies on Anti-Cancer Bioactive Natural Products. In: Atta-ur-Rahman. Studies in Natural Products Chemistry. Netherlands: Elsevier. Volume 72, 1st edition, 2022. ISBN: 978-0-128-23944-5.

 Published Abstracts

 

  1. Rodrigues, A. C. J.; Silva, T. F.; Detoni, Mariana Barbosa; Concato, Virginia Marcia; Tomiotto-Pelissier, Fernanda; Miranda-Sapla, M. M.; Bortoleti, Bruna; Gonçalves, M. D.; Carloto, Amanda; Sanfelice, Raquel Arruda; Cruz, Ellen Mayara Sousa ; Morais, J. M. B.; Bidóia, Danielle Larazin; Costa, I. N.; Pavanelli, W. R.; Conchon-Costa, I. A hiperglicemia modula a capacidade leishmanicida dos macrófagos, com redução de mediadores pró inflamatórios e aumento na atividade enzimática de sod e catalase In: XIII Simpósio Sul de Imunologia, 2022, Blumenal – SC. XIII Simpósio Sul de Imunologia. , 2022.

 

  1. Carloto, Amanda; Silva, T. F.; Detoni, Mariana Barbosa; Concato, Virginia Marcia; Tomiotto-Pelissier, Fernanda; Miranda-Sapla, M. M.; Bortoleti, Bruna; Gonçalves, Manoela Daiele; Rodrigues, Ana Carolina Jacob; Sanfelice, Raquel Arruda; Cruz, Ellen Mayara Sousa; Bidóia, Danielle Larazin; Costa, I. N.; Pavanelli, W. R.; Conchon-Costa, I. Diabetes reduz estresse oxidativo e favorece a infecção em camundongos c57bl/6 por leishmania amazonensis In: XIII Simpósio Sul de Imunologia, 2022, Blumenal – SC. XIII Simpósio Sul de Imunologia. , 2022.

 

  1. Caputo, W. L.; Silva, T. F.; Detoni, Mariana Barbosa; Concato, Virginia Marcia; Tomiotto-Pellissier, F.; Miranda-Sapla, M. M.; Bortoleti, Bruna; Gonçalves, M. D.; Jacob Rodrigues, Ana Carolina; Sanfelice, Raquel Arruda; Cruz, Ellen Mayara Sousa ; Carloto, Amanda; Bidóia, Danielle Larazin; Costa, I. N.; Pavanelli, W. R.; Conchon-Costa, I. Estímulo hiperglicêmico altera a resposta macrofágica desencadeada pela infecção por leishmania amazonensis In: XIII Simpósio Sul de Imunologia, 2022, Blumenal – SC. XIII Simpósio Sul de Imunologia. , 2022.

 

📚Top Noted Publication

 

3,3′,5,5′-Tetramethoxybiphenyl-4,4’diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line