Simone Giovannuzzi | Medicinal chemistry | Young Scientist Award

Published on by Young Scientists Awards

 Dr . Simone Giovannuzzi | Medicinal chemistry | Young Scientist Award

👨‍🏫Profile Summary

Dedicated researcher with a strong academic background in Pharmaceutical Sciences, specializing in drug development and computational chemistry. Recently awarded a PhD in Advanced Materials and Data Science, with expertise in multi-scale modeling and simulation of composite materials. Proficient in implementing computational methods and artificial intelligence models to advance pharmaceutical research. Fluent in English, French, and Arabic.

🌐 Professional Profiles

  1. Scopus Profile

 

  1. Orcid Profile

 

🎓 Education

PhD cum laude in Area del Farmaco e Trattamenti Innovativi: Curriculum Scienze Farmaceutiche NEUROFARBA Department, University of Florence, Italy Nov 2020 – Oct 2023 Qualification to practise the profession of Pharmacist National exam for professional qualification Jul 2020 5-year single-cycle Master’s Degree in Pharmaceutical Chemistry and Technologies Faculty of Pharmacy, University of Florence, Italy
Oct 2015 – Jun 2020

🔬Work Experience

Post-Doctoral Researcher in Area del Farmaco NEUROFARBA Department, University of Florence, Italy Nov 2023 – Present Tutor Senior in Area del Farmaco PNRR Plan “Orientamento attivo nella transizione scuola-Università”, Next Generation EU programme (NGEU) Oct 2023 – Present Tutor In-itinere for Chemistry, Organic Chemistry and Spectroscopic Methods Scuola di Scienze della Salute Umana, Corso di Scienze Farmaceutiche Applicate – Controllo Qualità (SFA-CQ), University of Florence, Italy Mar 2021 – Dec 2023 Internship Centre National de la Recherche Scientifique (CNRS), Montpellier, Occitanie, France Feb 2022 – Jul 2022

🔬Reviewer

Reviewer for international peer-reviewed scientific journals with high impact factor: Expert opinion on Therapeutic Patent Journal of Enzyme Inhibition and Medicinal Chemistry Frontiers Molecules Future Medicinal Chemistry Journal of the Turkish Chemical Society, Section A

🤝Major Ongoing Collaborations

Prof. J.Y. Winum, CNRS Montpellier, France, Prof. C. Capasso, CNR Napoli, Italy, Prof. G. De Simone, CNR Napoli, Italy, Prof. A.B. Vermelho, U. di Rio de Janeiro, Brazil, Prof. A. Aspatwar, U. Di Tampere, Finland, Prof. M. Bucciantini, U. Di Firenze, Italy, Prof. A. Ligresti, ICB Napoli, Italy Prof. F. Borges, U. di Porto, Portugal, Prof. Daniel P. Flaherty, U. di Purdue, USA, Mohamed N. Seleem, U. della Virgina, USA, Prof. S. Carradori, U. di Chieti, Italy

🧠Personal Skills

Excellent collaboration and coaching skills within a team, Outstanding problem-solving abilities, Strong adaptability and flexibility, Excellent active listening skills, Excellent creativity, Strong inclination towards research, Excellent multitasking and time management skills

💻Technical Skills

NMR, IR Spectroscopy, UV-Vis and Fluorescence Absorption, Multi-Step synthesis, Structure-Activity Relationship (SAR) Studies, Stopped-Flow Technique, Literature Review and Patent Analysis

🖥️Digital Skills

ChemDraw, SciFinder, Reaxys, Topspin, Origin, MestReNova, MS Office, E-Learning Platform, AI tools (ChatGPT, Perplexity)

📚Top Noted Publication

  1. Year: 2022
    • Journal: Composite Structure Journal
    • Title: Multiparametric modeling of composite materials based on non-intrusive PGD informed by multiscale analyses: Application for real-time stiffness prediction of woven composites.

 

  1. Year: 2023
    • Journal: Journal of the Mechanics and Physics of Solids
    • Title: Multiscale Thermodynamics-Informed Neural Networks (MuTINN) towards Fast and Frugal Inelastic Computation of Woven Composite Structures.

 

  1. Year: 2023 (under process)
    • Journal: Composite Structure Journal
    • Title: Multiparametric modeling of composite materials based on non-intrusive PGD informed by multiscale analyses: Application for real-time virtual testing of woven composites.

 

 

Virginia M. Concato-Lopes | drug-discovery | Best Researcher Award

Published on by Young Scientists Awards

Dr. Virginia M. Concato-Lopes | toxicology Award |Best Researcher Award

👨‍🏫Profile Summary

With a Ph.D. and Master’s in Experimental Pathology from Universidade Estadual de Londrina, Brazil, and ongoing postdoctoral research at Cedars-Sinai Medical Center, I specialize in the biogenesis of large oncosomes. My academic journey includes a Bachelor’s in Biomedicine from Universidade do Norte do Paraná. I’ve provided academic advisory for research projects investigating the antiproliferative properties of oregano essential oil in cancer cells. Passionate about advancing biomedical knowledge, I contribute to cutting-edge research and mentorship initiatives. For further information, please refer to my published papers or contact the respective academic institutions directly.

🌐 Professional Profiles

🎓 Education

Postdoctoral Fellow in Biogenesis of Large Oncosomes Cedars-Sinai Medical Center, Los Angeles, California, United States (2023 – Current), Ph.D. in Experimental Pathology Universidade Estadual de Londrina, Londrina, Paraná, Brazil (2019 – 2023), Master in Experimental Pathology
Universidade Estadual de Londrina, Londrina, Paraná, Brazil (2017 – 2019) Bachelor of Biomedicine Universidade do Norte do Paraná, Paraná, Brazil (2013 – 2016).

👨‍🏫Academic Advisory

Milena Cremer de Souza: Evaluating the antiproliferative capacity of Oregano Essential Oil (Origanum vulgare) on PC-3 prostate cancer cells. (2022) Degree: Ciências Biológicas (Biological Sciences) Institution: Universidade Estadual do Norte do Paraná Funding: Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Maria Beatriz Madureira: Exploring the antiproliferative activity of oregano oil in liver carcinoma tumor lines. (2021) Degree: Biomedicine Institution: Philadelphia University Center  For further details, please refer to the respective academic papers or contact the institutions directly.

Published article (first author publication)

  1. Concato-Lopes, V. M., Gonçalves-Lens, M. D., Tomiotto-Pellissier, F., Detoni, M. B., Cruz, E. M. S., Bortoleti, B. T. D. S., Carloto, A. C. M., Rodrigues, A. C. J., Silva, T. F., Siqueira, E. D. S., De Matos, R. L. N., Alves Cardoso, I. L., Conchon-Costa, I., Lazarin-Bidoia, D., Arakawa, N. S., Dekker, R. F., Mantovani, M. S., & Pavanelli, W. R. Trilobolide-6-O-isobutyrate from Sphagneticola trilobata acts by inducing oxidative stress, metabolic changes and apoptosis-like processes by caspase 3/7 activation of human lung cancer cell lines. Phytomedicine, v. 155536, 2024.
  1. Concato-Lopes, V. M., Silva, T. F., Detoni, M. B., Cruz, E. M. S., Gonçalves, M. D., Da Silva Bortoleti, B. T., Tomiotto-Pellissier, F., Carloto, A. C. M., Madureira, M. B., Rodrigues, A. C. J., Schirmann, J. G., Barbosa-Dekker, A. M., Dekker, R. F., Conchon-Costa, I., Panis, C., Lazarin-Bidóia, D., Miranda-Sapla, M. M., Mantovani, M. S., & Pavanelli, W. R. 3,3′,5,5′-Tetramethoxybiphenyl-4,4’diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line. Biomedicine & Pharmacotherapy, 170, 115979, 2024.
  1. Concato, Virginia Marcia; Tomiotto-Pellissier, Fernanda; Silva, Taylon Felipe; Gonçalves, Manoela Daiele; Da Silva Bortoleti, Bruna Taciane; Detoni, Mariana Barbosa; Da Silva Siqueira, Elaine; Jacob Rodrigues, Ana Carolina; Schirmann, Jéseka Gabriela; De Melo Barbosa-Dekker, Aneli; Costa, Idessania Nazareth; Conchon-Costa, Ivete; Miranda-Sapla, Milena Menegazzo; Mantovani, Mario Sergio; Pavanelli, Wander Rogério. 3,3-,5,5–tetramethoxybiphenyl-4,4-diol induces cell cycle arrest in G2/M phase and apoptosis in human non-small cell lung cancer A549-cells. Chemico-Biological Interactions, v. 2020, p. 109133, 2020.

 

Published book chapters

  1. Silva, T. F.; Tomiotto-Pellissier, F.; Sanfelice, Raquel Arruda; Gonçalves, Manoela Daiele; Bortoleti, Bruna; Detoni, Mariana Barbosa; Rodrigues, Ana Carolina Jacob; Carloto, Amanda; Concato, Virginia Marcia; Siqueira, Elaine Da Silva; Costa, I. N.; Pavanelli, Wander; Conchon-Costa, Ivete; Miranda-Sapla, M. M. A 21st Century Evil: Immunopathology and New Therapies of COVID-19 In: CORONAVIRUS DISEASE (COVID-19): PATHOPHYSIOLOGY, EPIDEMIOLOGY, CLINICAL MANAGEMENT AND PUBLIC HEALTH RESPONSE.1 ed.Lausanne: Frontiers Media SA, 2023, v.C, p. 164-194.

 

  1. Fagundes, Tatiane Renata; Kawassaki, A. C. B.; Concato, Virginia Marcia; Assolini, João Paulo; Silva, Taylon Felipe; Goncalves, M. D.; Da Silva Siqueira, Elaine; Sahd, C. S.; Inoue, Fabricio Seidy Ribeiro; Silva, T. P.; Lima, D. M.; Ferreira, Mariane Okamoto; Conchon-Costa, Ivete; Pavanelli, W. R.; Panis, Carolina. Impact of Pesticides on Immune-Endocrine Disorders and Its Relationship to Cancer Development In: Handbook of Cancer and Immunology.30, 2023, p. 1-30.

 

  1. Tomiotto-Pellissier, Fernanda; Gonçalves, Manoela Daiele; Silva, Taylon Felipe; Concato, Virgínia Márcia; Bortoleti, Bruna Taciane da Silva; Arakawa, Nilton Syogo; Conchon-Costa, Ivete; Pavanelli, Wander Rogério; and Panis, Carolina. Structure-Activity Relationship (SAR) Studies on Anti-Cancer Bioactive Natural Products. In: Atta-ur-Rahman. Studies in Natural Products Chemistry. Netherlands: Elsevier. Volume 72, 1st edition, 2022. ISBN: 978-0-128-23944-5.

Published book chapters

  1. Silva, T. F.; Tomiotto-Pellissier, F.; Sanfelice, Raquel Arruda; Gonçalves, Manoela Daiele; Bortoleti, Bruna; Detoni, Mariana Barbosa; Rodrigues, Ana Carolina Jacob; Carloto, Amanda; Concato, Virginia Marcia; Siqueira, Elaine Da Silva; Costa, I. N.; Pavanelli, Wander; Conchon-Costa, Ivete; Miranda-Sapla, M. M. A 21st Century Evil: Immunopathology and New Therapies of COVID-19 In: CORONAVIRUS DISEASE (COVID-19): PATHOPHYSIOLOGY, EPIDEMIOLOGY, CLINICAL MANAGEMENT AND PUBLIC HEALTH RESPONSE.1 ed.Lausanne: Frontiers Media SA, 2023, v.C, p. 164-194.

 

  1. Fagundes, Tatiane Renata; Kawassaki, A. C. B.; Concato, Virginia Marcia; Assolini, João Paulo; Silva, Taylon Felipe; Goncalves, M. D.; Da Silva Siqueira, Elaine; Sahd, C. S.; Inoue, Fabricio Seidy Ribeiro; Silva, T. P.; Lima, D. M.; Ferreira, Mariane Okamoto; Conchon-Costa, Ivete; Pavanelli, W. R.; Panis, Carolina. Impact of Pesticides on Immune-Endocrine Disorders and Its Relationship to Cancer Development In: Handbook of Cancer and Immunology.30, 2023, p. 1-30.

 

  1. Tomiotto-Pellissier, Fernanda; Gonçalves, Manoela Daiele; Silva, Taylon Felipe; Concato, Virgínia Márcia; Bortoleti, Bruna Taciane da Silva; Arakawa, Nilton Syogo; Conchon-Costa, Ivete; Pavanelli, Wander Rogério; and Panis, Carolina. Structure-Activity Relationship (SAR) Studies on Anti-Cancer Bioactive Natural Products. In: Atta-ur-Rahman. Studies in Natural Products Chemistry. Netherlands: Elsevier. Volume 72, 1st edition, 2022. ISBN: 978-0-128-23944-5.

 Published Abstracts

 

  1. Rodrigues, A. C. J.; Silva, T. F.; Detoni, Mariana Barbosa; Concato, Virginia Marcia; Tomiotto-Pelissier, Fernanda; Miranda-Sapla, M. M.; Bortoleti, Bruna; Gonçalves, M. D.; Carloto, Amanda; Sanfelice, Raquel Arruda; Cruz, Ellen Mayara Sousa ; Morais, J. M. B.; Bidóia, Danielle Larazin; Costa, I. N.; Pavanelli, W. R.; Conchon-Costa, I. A hiperglicemia modula a capacidade leishmanicida dos macrófagos, com redução de mediadores pró inflamatórios e aumento na atividade enzimática de sod e catalase In: XIII Simpósio Sul de Imunologia, 2022, Blumenal – SC. XIII Simpósio Sul de Imunologia. , 2022.

 

  1. Carloto, Amanda; Silva, T. F.; Detoni, Mariana Barbosa; Concato, Virginia Marcia; Tomiotto-Pelissier, Fernanda; Miranda-Sapla, M. M.; Bortoleti, Bruna; Gonçalves, Manoela Daiele; Rodrigues, Ana Carolina Jacob; Sanfelice, Raquel Arruda; Cruz, Ellen Mayara Sousa; Bidóia, Danielle Larazin; Costa, I. N.; Pavanelli, W. R.; Conchon-Costa, I. Diabetes reduz estresse oxidativo e favorece a infecção em camundongos c57bl/6 por leishmania amazonensis In: XIII Simpósio Sul de Imunologia, 2022, Blumenal – SC. XIII Simpósio Sul de Imunologia. , 2022.

 

  1. Caputo, W. L.; Silva, T. F.; Detoni, Mariana Barbosa; Concato, Virginia Marcia; Tomiotto-Pellissier, F.; Miranda-Sapla, M. M.; Bortoleti, Bruna; Gonçalves, M. D.; Jacob Rodrigues, Ana Carolina; Sanfelice, Raquel Arruda; Cruz, Ellen Mayara Sousa ; Carloto, Amanda; Bidóia, Danielle Larazin; Costa, I. N.; Pavanelli, W. R.; Conchon-Costa, I. Estímulo hiperglicêmico altera a resposta macrofágica desencadeada pela infecção por leishmania amazonensis In: XIII Simpósio Sul de Imunologia, 2022, Blumenal – SC. XIII Simpósio Sul de Imunologia. , 2022.

 

📚Top Noted Publication

 

3,3′,5,5′-Tetramethoxybiphenyl-4,4’diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line