Manisha Nidhar | Pharmaceutical Chemistry | Young Scientist Award

Published on by Young Scientists Awards

Dr. Manisha Nidhar | Pharmaceutical Chemistry | Young Scientist Award

Jaipur National University | India

Dr. Manisha Nidhar is an accomplished Associate Professor at the School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, specializing in medicinal chemistry, computer-aided drug design, and the synthesis and biological evaluation of bioactive molecules as antidiabetic agents. She has a strong foundation in synthetic organic chemistry and extensive experience in both teaching and research in pharmaceutical sciences. Her doctoral research at Banaras Hindu University focused on designing and synthesizing bioactive compounds, including pyridazine, pyrazole, β-amino carbonyl, and triazole derivatives, as potential DPP-4 inhibitors for type-2 diabetes, combining laboratory synthesis, purification, and characterization with in-silico studies such as molecular docking, molecular dynamics simulations, and ADMET analyses, followed by comprehensive biological evaluation. Dr. Nidhar has contributed significantly to scientific literature, authoring numerous high-impact publications and book chapters, and has actively participated in workshops, conferences, and faculty development programs on drug design, innovative teaching, and research methodologies. She has guided postgraduate students in designing, synthesizing, and evaluating novel antidiabetic compounds and has played key roles in academic committees and collaborative projects. Proficient in computational tools and scientific software including Chemdraw, Schrodinger, Sybyl, and virtual docking platforms, she excels in scientific information retrieval and reference management. Dr. Nidhar is dedicated to advancing pharmaceutical education and research, combining her passion for teaching and pioneering research to address complex therapeutic challenges. She has 61 citations across 53 documents and an h-index of 5.

Featured Publications

  • Nidhar, M., Khanam, S., Sonker, P., Gupta, P., Mahapatra, A., Patil, S., Yadav, B. K., Singh, R. K., & Tewari, A. K. (2022). Click inspired novel pyrazole-triazole-persulfonimide & pyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents. Bioorganic Chemistry, 120, 105586.

  • Nidhar, M., Sonker, P., Sharma, V. P., Kumar, S., & Tewari, A. K. (2022). Design, synthesis, and in-silico & in vitro enzymatic inhibition assays of pyrazole-chalcone derivatives as dual inhibitors of α-amylase & DPP-4 enzyme. Chemical Papers.

  • Singh, V. P., Nidhar, M., Yadav, P., Kumar, R., Sonker, P., & Tewari, A. K. (2022). Design, synthesis, molecular modeling of heterodimer and inhibitors of α-amylase as hypoglycemic agents. Molecular Diversity.

  • Nidhar, M., Kumar, V., Mahapatra, A., Gupta, P., Sonker, P., et al. (2023). Lead modification on sitagliptin via computational studies; Synthesis of pyrazole containing β-amino carbonyls for the treatment of type-2 diabetes. Chemical Biology and Drug Design, 101(3), 638–649.

  • Nidhar, M., Kumar, V., Mahapatra, A., et al. (2023). Ligand-based designing of DPP-4 inhibitors via hybridization; synthesis, docking, and biological evaluation of pyridazine-acetohydrazides. Molecular Diversity, 27, 2729–2740.