Ashwani Patil | Cancer Biology | Best Scholar Award

Dr. Ashwani Patil | Cancer Biology | Best Scholar Award

Assistant Professor, Dr. D. Y. Patil Institute of Pharmaceutical Sciences & Research India

Dr. Ashwani Patil is a passionate pharmacologist specializing in neurological disorders and cancer research. He completed his Ph.D. in Pharmacology from the Institute of Chemical Technology (ICT), Mumbai, with a focus on preclinical drug development. His research at Bhabha Atomic Research Centre and NIRRH Mumbai deepened his expertise in molecular mechanisms underlying complex diseases. With hands-on experience in animal handling, molecular techniques, and pharmacological testing, he has contributed significantly to understanding disease pathology and potential therapeutic targets for cancer and neurological disorders.

Professional Profile 

Scopus

Scholar

πŸŽ“Education

Ph.D. in Pharmaceutical Tech. (Pharmacology), Institute Of Chemical Technology, Mumbai (2024). M. Pharmacy (Pharmacology), R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur (2018). Bachelor of Pharmacy, A.R.A College of Pharmacy, Dhule (2016)

πŸ’ΌExperience

Junior Research Fellow, R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur (2018-2019). Research Scholar, Institute of Chemical Technology, Mumbai (2022-Present). Assistant Professor, Dr. D Y Patil Institute of Pharmaceutical Science and Research, Pune (2019-2020, 2024). Expertise in preclinical drug studies, rodent surgery, data analysis, and project planning.

πŸ†Award and Honor

DAE-ICT Fellowship, 2024. 1st Position in Poster Presentation, 7th International Conference on β€œEmerging Trends in Drug Development and Delivery” (2024). Research Excellence Award, GEU, Dehradun (2015). Best Paper Presentation Award, TriboIndia 2023, NIT Srinagar

πŸ”¬ Research Focus

Dr. Patil’s research spans preclinical drug development, focusing on neurological disorders and cancer. His work investigates therapeutic targets, pharmacodynamics, and the molecular mechanisms of disease pathology. Key areas of interest include rodent models, drug efficacy, safety profiles, and mitochondrial toxicity. His publications highlight cancer cell cytotoxicity and cardioprotective effects, contributing to the understanding of pharmacological agents in disease treatment.

Publications Top Noted

1. Title: Cardioprotective effect of CB1 receptor antagonist AM251 against Ξ² receptor-stimulated myocardial infarction via modulation of NF-kB signaling pathway in diabetic mice

Year: 2024
Authors: Pawar, H.D., Patil, Y., Patil, A., Ojha, S., Goyal, S.N.
Citation: Heliyon, 10(15), e35138
Citations: 0

2. Title: Mitochondria-targeted derivative of pterostilbene, a dietary phytoestrogen, exhibits superior cancer cell cytotoxicity via mitochondrial superoxide mediated induction of autophagy

Year: 2023
Authors: Ibrahim, M.K., Nandha, S.R., Patil, A.S., Sharma, D., Sandur, S.K.
Citation: Advances in Redox Research, 8, 100071
Citations: 1

3. Title: Mitochondriotropic Derivative of Ethyl Ferulate, a Dietary Phenylpropanoid, Exhibits Enhanced Cytotoxicity in Cancer Cells via Mitochondrial Superoxide-Mediated Activation of JNK and AKT Signalling

Year: 2023
Authors: Patil, A.S., Ibrahim, M.K., Sathaye, S., Sharma, D., Sandur, S.K.
Citation: Applied Biochemistry and Biotechnology, 195(3), 2057–2076
Citations: 2

4. Title: Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review

Year: 2020
Authors: Patil, A.S., Mahajan, U.B., Agrawal, Y.O., Sharma, C., Goyal, S.N.
Citation: Biomedicine and Pharmacotherapy, 132, 110889
Citations: 17

5. Title: Protective effect of omeprazole and lansoprazole on Ξ²-receptor stimulated myocardial infarction in Wistar rats

Year: 2019
Authors: Patil, A.S., Singh, A.D., Mahajan, U.B., Ojha, S., Goyal, S.N.
Citation: Molecular and Cellular Biochemistry, 456(1-2), 105–113
Citations: 17

 

Di Zhu| Immuno-oncology| Best Researcher Award

Mr. Di Zhu| Immuno-oncology| Best Researcher Award

Professor at Fudan University,  China

Di Zhu is a Professor in the Department of Pharmacology at Fudan University, specializing in immuno-oncology and cancer research. Born on October 13, 1983, he holds a Ph.D. in Biochemistry and Molecular Biology. With over 8 years of academic experience, he has pioneered groundbreaking therapies targeting colorectal cancer. Recognized globally for his contributions to cancer immunotherapy, he combines innovative research with clinical applications to improve patient outcomes.

Profile

Scholar

Education πŸŽ“

Ph.D. in Biochemistry & Molecular Biology (2005–2010), Shanghai Institute of Biochemistry and Cell Biology, CAS. Postdoctoral Fellow (2011–2015), Dana-Farber Cancer Institute, Harvard University. Undergraduate studies at Shandong University, earning accolades like the National Sci. & Tech. Challenge Cup (2004).

Experience πŸ’Ό

Researcher: Fudan University, School of Basic Medical Sciences (2021–Present). Researcher: Minhang & Zhongshan Hospitals, Fudan University (2017–Present). Researcher: Fudan University, School of Pharmacy (2016–2021). Led 12 projects, supervised 16 research scholars, and organized 5 workshops globally.

Awards and Honors πŸ…

Gold Medal: Global Life & Health Technology Concept Validation (2024). Excellence Award: Hai Ju Ying Cai Global Innovation (2024). Outstanding Young Scientist: Shanghai Society of Biotechnology (2022). 1000 Talent Young Award: CPC Central Committee (2016). Multiple national and international recognitions for cancer research.

Research Focus πŸ”¬

Therapies: Pioneered BCL9/Ξ²-catenin inhibitors for colorectal cancer. Immunotherapy: Enhanced T-cell responses and reduced immune resistance. Innovative Molecules: Developed selective inhibitors for challenging pathways. Publications: Authored impactful research in top journals, advancing cancer treatment.

Conclusion

Dr. Di Zhu exemplifies the qualities of a world-class researcher. His groundbreaking contributions to cancer therapy, robust academic output, and numerous accolades strongly support his nomination for the Best Researcher Award, affirming his leadership and innovation in the field of pharmacology and immuno-oncology.

Publication

 

  • Clinical cancer immunotherapy: Current progress and prospects
    Authors: C Liu, M Yang, D Zhang, M Chen, D Zhu
    Journal: Frontiers in Immunology 13, 961805
    Citations: 140 (2022)

 

  • Wnt signaling pathway in cancer immunotherapy
    Authors: Y Zhou, J Xu, H Luo, X Meng, M Chen, D Zhu
    Journal: Cancer Letters 525, 84-96
    Citations: 125 (2022)

 

  • IFNΞ± potentiates anti–PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
    Authors: B Hu et al., including D Zhu
    Journal: Cancer Discovery 12 (7), 1718-1741
    Citations: 123 (2022)

 

  • The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
    Authors: DI Zhu et al.
    Journal: Nature Medicine 21 (6), 572-580
    Citations: 116 (2015)

 

  • Pharmacological inhibition of Ξ²-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells
    Authors: M Feng et al., including D Zhu
    Journal: Science Advances 5 (5), eaau5240
    Citations: 100 (2019)

 

  • Cyclophilin A and CD147: Novel therapeutic targets for the treatment of COVID-19
    Authors: C Liu, A von Brunn, D Zhu
    Journal: Medicine in Drug Discovery 7, 100056
    Citations: 91 (2020)

 

  • T-cell-based immunotherapy in colorectal cancer
    Authors: M Feng, Z Zhao, M Yang, J Ji, D Zhu
    Journal: Cancer Letters 498, 201-209
    Citations: 67 (2021)

 

  • Targeting the tumor immune microenvironment for cancer therapy in human gastrointestinal malignancies
    Authors: Y Zhang et al., including D Zhu
    Journal: Cancer Letters 458, 123-135
    Citations: 55 (2019)

 

  • Targeting Cyclophilin A and CD147 to Inhibit Replication of SARS-CoV-2 and SARS-CoV-2-Induced Inflammation
    Authors: F Yang et al., including D Zhu
    Journal: Molecular Pharmacology
    Citations: 1 (2023)

 

  • New Approaches Targeting Immuno-oncology and Tumor Microenvironment
    Authors: D Zhu, F He
    Book Chapter: Cancer Treatment: An Interdisciplinary Approach, 63-90
    Citations: 1 (2022)

 

 

 

Mohammad Khosravi | Immunotherapy | Excellence in Innovation

Assoc Prof Dr. Mohammad Khosravi | Immunotherapy | Excellence in Innovation

Assoc Prof Dr. Shahid Chamran University of Ahvaz Iran

πŸ‘©β€πŸ”¬ A highly skilled immunologist and veterinarian with a Ph.D. from Tehran University, specializing in molecular characterization and immunology techniques. Experienced in cell culture, gene characterization, protein analysis, and chromatography. Proficient in serology techniques, immunization, and animal handling. Skilled in bioinformatics analysis and extensive knowledge of SPSS and Microsoft Office Suite. Adept at teaching fundamental and advanced immunology to both D.V.M. and Ph.D. students. Demonstrated expertise in avian immunology and diagnostic techniques. Accomplished in research and teaching, contributing significantly to the field of immunology and veterinary medicine.🌟

 

Profile

Scopus

 

Education πŸ“š

PhD in Immunology: Tehran University, Tehran, Iran, 2013.Thesis: Molecular characterization of chicken class II transactivator gene.DVM (Doctor of Veterinary Medicine): Shahrekord University, Chaharmahal bakhteyari, Iran, 2007.Thesis: A comparison of ELISA and histopathology for the detection of paratuberculosis in dairy cattle.

Research Experience and Technical Skills πŸ”¬

Cell culture (primary and immortalized cell lines).Stem cell isolation technique.Isolation of leukocyte subsets.Purification of antibody subsets.Gene characterization: PCR, RT-PCR, QRT-PCR, Real Time-PCR, Gene cloning, Bioinformatics analysis.Protein and Oligosaccharide SDS-PAGE.Western blotting.Serology techniques: ELISA, Agglutination, Precipitation, Hemagglutination.Chromatographic techniques: Affinity, Ion-exchange, Gel-filtration.Purification of protein and carbohydrate.Immunization techniques.Animal handling.Extensive experience of SPSS, Microsoft Word, Excel, PowerPoint.Hapten immunization (Preparation of the hyper immune sera against drugs and metals).Synthesis of the metal nanoparticles (Fe, Cu, Au, Zn).Synthesis of the immunomagnetic beads for separation of the microorganisms, cells, drugs, and metals.Synthesis of the latex agglutination beads for detection of the cells, drugs, and metals.

Teaching Experience (2013-2022) πŸ“–

At Shahid Chamran University of Ahvaz, Khuzestan, Iran:

  • Fundamental Immunology for D.V.M students.
  • Advanced Immunology for Ph.D students of bacteriology.
  • Serology Technique for D.V.M students.
  • Avian Immunology for PhD students of poultry hygiene and diseases.
  • Diagnostic Immunology for Ph.D students of clinical pathology.

Publications Top Notes πŸ“

  1. Title: Quorum quenching probiotics modulated digestive enzymes activity, growth performance, gut microflora, haemato-biochemical parameters and resistance against Vibrio harveyi
    • Authors: R Ghanei-Motlagh, T Mohammadian, D Gharibi, M Khosravi, E Mahmoudi, …
    • Journal: Aquaculture
    • Volume: 531
    • Pages: 735874
    • Year: 2021

 

  1. Title: Quorum Quenching Properties and Probiotic Potentials of Intestinal Associated Bacteria in Asian Sea Bass Lates calcarifer
    • Authors: R Ghanei-Motlagh, T Mohammadian, D Gharibi, S Menanteau-Ledouble, …
    • Journal: Marine drugs
    • Volume: 18
    • Issue: 1
    • Pages: 23
    • Year: 2019

 

  1. Title: Feed supplementation with quorum quenching probiotics with anti-virulence potential improved innate immune responses, antioxidant capacity and disease resistance in Asian …
    • Authors: R Ghanei-Motlagh, D Gharibi, T Mohammadian, M Khosravi, E Mahmoudi, …
    • Journal: Aquaculture
    • Volume: 535
    • Pages: 736345
    • Year: 2021

 

  1. Title: Antibacterial effects of Aloe vera extracts on some human and animal bacterial pathogens
    • Authors: D Gharibi, M Khosravi, Z Hosseini, F Boroun, SK Barzgar, A Forughi Far
    • Journal: Journal of Medical Microbiology and Infectious Diseases
    • Volume: 3
    • Issue: 1
    • Pages: 6-10
    • Year: 2015