Angelika Długosz-Pokorska | cancer research | Women Researcher Award

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Ā Dr. Angelika Długosz-Pokorska | cancer research |Women Researcher Award

Ā Dr at Medical University of ÅĆ³dÅŗ,Ā  Poland

A dedicated researcher and project leader at the Medical University of Lodz, Poland, with expertise in pharmacological characterization and anticancer drug development. As Principal Investigator and Co-investigator, led projects funded by prestigious grants like OPUS and SONATA, focusing on opioid peptide analogs and alpha-methylidene-delta-lactones. Supervising international student exchanges and engaging in expert activities, workshops, and editorial work. Recognized with numerous awards for scientific excellence, including Rector’s Awards and IF=8.638 for publication series on opioid mimetics and glutathione peroxidase. Committed to advancing medical science through innovative research and academic leadership.

Profile

  1. Scopus

 

  1. Orcid

šŸ“œ Employment History:

Research Associate (2017-present) Medical University of Lodz, Poland; Faculty of Medicine. Co-investigator (2016-2021)
Project: Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple receptors
Grant: OPUS 9, project ID 2015/17/B/ST5/00153. Principal Investigator (2016-2021) Project: Analysis of the anticancer activity of new synthetic alpha-methylidene-delta-lactones in selected cell lines Grant: SONATA, project ID 2015/17/D/NZ3/02226. Supervisor, Project Manager, and Principal Investigator (2018-present) Project: Analysis of the anticancer activity and molecular mechanism of action of new hybrid molecules containing uracil skeleton with an exo-cyclic methylene group Grant: PRELUDIUM13, project ID UMO-2017/25/N/NZ3/01039

šŸ“š Short Research Training:

University of Rouen, France (2014) Laboratoire de Neuropsychopharmacologie ExpƩrimentale

šŸŒ Activities:

  • Expert Activity/Reviewer (2024)
    Platform: Qeios
  • International Student Exchanges and ERASMUS Supervision (2024)
    Engaging in initiatives and participating in European Union programs, overseeing ERASMUS students.
  • Participation in Scientific Workshops and Research Teams (2024)
    Engaging in workshops aimed at exchanging experiences, self-improvement, and organization.
  • Editorial Work (2023-present)
    Journal: Reviewer for Breast Cancer-Tokyo, ISSN 1340-6868, eISSN 1880-4233.

šŸ† Awards and Distinctions:

2022: First-level Special Award for Outstanding Didactic Work by Academic Teachers Medical University of Lodz.

2020: Team Distinction from the Faculty of Chemistry Nicolaus Copernicus University in Toruń Rector’s Award Medical University of Lodz Second-degree scientific award for a series of publications titled: ‘Investigation of the Anticancer Properties of Synthetic Analogues of Compounds Isolated from Plants’. (Impact Factor – 8.034). Polish Intelligent Development Award – Nomination.

2019: Investigation of Anticancer Activity of Synthetic Analogues of Methylenolactones”, IF=4.026PTBioch Bursary Scholarship 44th FEBS Congress “From Molecules to Living Systems”. Rector’s Award Medical University of Lodz Second Prize for Publication: ‘Synthetic Analogues of Coumarin as Novel Agents with Anticancer Activity’. (Impact Factor = 4.173). Rector’s Award Medical University of Lodz Team Second award for Publication Series:

2017: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Synthesis and Investigation of Biological Activity of Opioid Mimetics and Glutathione Peroxidase”. (IF=8.638). Rector’s Award Medical University of Lodz Team First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Dicoumarins”. (IF=6.221) “Investigation of Anticancer Activity of Sesquiterpene Lactones”. (IF=4.994)

2016: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Lactones in Combination with Known Anticancer Drugs”. (IF = 8.835)

Publications Top Notes šŸ“

  • Title: Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluation-Part I
    • Authors: Laskowska, A., Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., et al.
    • Journal: Materials
    • Year: 2024
    • Volume: 17
    • Pages: 1ā€“15
    • Summary: This study focuses on the synthesis of new chiral Ī²-carbonyl selenides and evaluates their antioxidant and anticancer activities, providing valuable insights into potential therapeutic agents.

 

  • Title: New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF7 Cancer Cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Biologics: Targets and Therapy
    • Year: 2023
    • Volume: 17
    • Pages: 69ā€“83
    • Summary: This article presents a novel uracil analog with potential to reverse resistance to Taxol in MCF7 cancer cells, indicating its promising role as an anticancer agent.

 

  • Title: New Uracil Analog- U-359 can Reverse Resistance to Taxol in MCF-7 cancer cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Acta Biochimica Polonica
    • Year: 2023
    • Volume: 70
    • Pages: 56
    • Summary: This study explores another uracil analog’s potential to reverse resistance to Taxol in MCF-7 cancer cells, indicating a promising avenue for further research.

 

  • Title: The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides
    • Authors: Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., Jastrzębska, A., et al.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Pages: 1ā€“11
    • Summary: This research investigates the impact of long carbon chains on the antioxidant and anticancer properties of N-substituted benzisoselenazolones and corresponding diselenides, providing valuable insights into structure-activity relationships.

 

  • Title: Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics
    • Authors: Laskowska, A., Pacuła-Miszewska, A., Długosz-Pokorska, A., et al.
    • Journal: Materials
    • Year: 2022
    • Volume: 16
    • Pages: 1ā€“14
    • Summary: This study explores the modification of GPx mimetics’ activity through the attachment of chiral functional groups, offering potential strategies for enhancing therapeutic effects.

 

Mi Rim Lee |cancer science Award | Young Scientist Award

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Ms. Mi Rim Lee| Genomics Award | Young Scientist Award

šŸ‘Øā€šŸ«Profile Summary

John Doe is a dedicated Ph.D. candidate in Cancer Biomedical Science at the National Cancer Center Graduate School of Cancer Science and Policy. With a solid academic background in Biomaterials, he obtained both his Master’s and Bachelor’s degrees from Pusan National University. John’s achievements include prestigious scholarships and poster awards from esteemed institutions like the Korean Society of Laboratory Animal Science and the Korean Cancer Association. His research interests lie at the intersection of cancer biology and biomaterials, aiming to contribute novel insights into cancer treatment and therapy development. John’s academic excellence and commitment to cancer research mark him as a promising young scientist in the field.

šŸŒ Professional Profiles

EducationšŸŽ“

2019.09~present: National Cancer Center Graduate School of Cancer Science and Policy Major: Cancer Biomedical Science Degree: Ph.D. candidate, 2017.03~2019.02: Pusan National University Major: Biomaterial Degree: MS. 2011.03~2017.02: Pusan National University Major: Biomaterial Degree: BA.

Awards šŸ†

2018.02: Title: Scholarship Student Institution: Korean Society of Laboratory Animal Science 2018.07: Title: Poster Award Institution: Korean Society of Laboratory Animal Science 2019.01: Title: Academic Award Institution: College of Life and Resources Sciences, Pusan National University 2021.06: Title: Poster Award Institution: Korean Cancer Associati

šŸ“šTop Noted Publication

  1. Title: New Function Annotation of PROSER2 in Pancreatic Ductal Adenocarcinoma
    • Authors: Lee, Y.-S., Im, J., Yang, Y., … Hwang, H., Kim, Y.-H.
    • Journal: Journal of Proteome Research
    • Publication Year: 2024
    • Volume: 23
    • Issue: 3
    • Pages: 905ā€“915

 

  1. Title: Application of plasma circulating KRAS mutations as a predictive biomarker for targeted treatment of pancreatic cancer
    • Authors: Lee, M.R., Woo, S.M., Kim, M.K., … Kim, Y.-H., Kong, S.-Y.
    • Journal: Cancer Science
    • Publication Year: 2024

 

  1. Title: Complexation of drug and hapten-conjugated aptamer with universal hapten antibody for pancreatic cancer treatment
    • Authors: Choi, S.I., Lee, Y.-S., Lee, Y.M., … Kim, Y.-H., Kim, I.-H.
    • Journal: Journal of Controlled Release
    • Publication Year: 2023
    • Volume: 360
    • Pages: 940ā€“952

 

  1. Title: Refining Classification of Cholangiocarcinoma Subtypes via Proteogenomic Integration Reveals New Therapeutic Prospects
    • Authors: Cho, S.Y., Hwang, H., Kim, Y.-H., … Park, S.-J., Woo, S.M.
    • Journal: Gastroenterology
    • Publication Year: 2023
    • Volume: 164
    • Issue: 7
    • Pages: 1293ā€“1309

 

  1. Title: Establishment of Patient-Derived Organoids Using Ascitic or Pleural Fluid from Cancer Patients
    • Authors: Choi, W., Kim, Y.-H., Woo, S.M., … Lee, K.S., Kong, S.-Y.
    • Journal: Cancer Research and Treatment
    • Publication Year: 2023
    • Volume: 55
    • Issue: 4
    • Pages: 1077ā€“1086

 

  1. Title: Establishment of Patient-derived Preclinical Models for Invasive Papillary Cholangiocarcinoma
    • Authors: Mwesige, B., Lee, M.R., Lee, Y.-S., … Woo, S.M., Kim, Y.-H.
    • Journal: Anticancer Research
    • Publication Year: 2022
    • Volume: 42
    • Issue: 1
    • Pages: 599ā€“608