Srinivasan Jayakumar | Organic | Best Researcher Award

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 Dr . Srinivasan Jayakumar | Organic | Best Researcher Award

👨‍🏫Profile Summary

Dynamic, versatile, and self-motivated Research Scientist with eight years of expertise in Synthetic Organic and Medicinal Chemistry. A pragmatic strategist adept at crafting research strategies aligned with organizational priorities. Proven ability to manage complex research schedules, delivering results on demanding projects.🧪

Passionate about hands-on organic synthesis, possessing extensive knowledge in modern organic chemistry, crystallization techniques, metal-catalyzed reactions, and multi-step synthesis. Proficient in purification using flash column chromatography, Combi Flash, Gilson, Isolera, and spectroscopic characterization of novel compounds. Specialized in Drug discovery, Lead optimization, and Synthesis Characterization of Anti-viral Drugs, focusing on viral infections, macular degeneration, and neuropathic pain🌐

🌐 Professional Profiles

 

🎓 Education

Ph.D. in Organic Chemistry, National Tsing Hua University, Taiwan (2011-2020), Title: Synthesis of Quinolinoquinolines by a New Domino Reaction and Hinged Aromatic Compounds against Enterovirus 71, Masters in Chemistry, Gurunanak College, University of Madras, India (2003-2005) Bachelors in Chemistry, Gurunanak College, University of Madras, India (2000-2003)

🔬 Professional and Research Experience

Rensselaer Polytechnic Institute, Troy, NY (Jan 2022 – Present) Postdoctoral Research Associate (Department of Chemistry and Chemical Biology) Title: Synthesis of GlyT2 inhibitors to treat Neuropathic pain Albany College of Pharmacy and Health Sciences, Albany, NY (July 2020 – Dec 2021) Postdoctoral Research Associate (Department of Basic and Clinical Sciences, Department of Pharmaceutical Sciences) Title: Age-Related Macular Degeneration Syngene International Limited, India (June 2006 – Jan 2011) Research Associate II Job responsibilities include research and development of new synthetic pathways, Suzuki coupling, Grignard reaction, and monitoring reaction progress using analytical techniques.

📚 Editorial Board and Committee (2023-Present)

Editorial board member at the International Journal of Pharmacy and Chemistry, Editorial board member at Online Journal of Chemistry. Editorial board member at the International Journal of Science and Management Studies Editorial board member at Archives of Pharmacy & Pharmacology Research Community associate membership at ACS. Serving as a member of the Selection Committee for Graduate Scholarships and Awards at the University of Ottawa.

🔍Journal Reviewer and Peer- Reviewing

Demonstrated expertise in the organic and medicinal field through service as a reviewer for Eleven reputable organic chemistry journals. Reviewer at Pharmacy & Pharmacology International Journal.

🌟 Research Highlight

Participated in extramurally funded small molecule drug discovery research focusing on indications like dry AMD, neuropathic pain, and viral infections. Key projects include the design and development of novel transthyretin (TTR) tetramer kinetic stabilizers and inhibitors of glycine transporter 2 (GlyT2).

🔬Skillset

Synthesis, purification, and characterization of structurally diverse organic compounds, Broad knowledge of Synthetic Organic and Medicinal chemistry. Experience with using Chem Draw, Chem Sketch, ISIS draw, Beilstein, Reaxys, and SciFinder. Proven experience in synthetic organic chemistry, process optimization, and technology transfer. Purification using reverse-phase preparative HPLC and method development. Expertise in scale-up, product development, mass spectrometry, lead optimization, and peer

 

📚Top Noted Publication

  • “The efficacy of the analgesic GlyT2 inhibitor, ORG25543, is determined by two connected allosteric sites.”
    • Authors: Cantwell Chater, Ryan; Quinn, Ada; Wilson, Katie; Frangos, Zachary; Sutton, Patrick; Jayakumar, Srinivasan; Cioffi, Christopher; O’Mara, Megan; Vandenberg, Robert
    • Published: J. Neurochem. 2023, 00, 1–20
    • DOI: 10.1111/jnc.16028

 

  • “Novel Phenylene Lipids That Are Positive Allosteric Modulators of Glycine Receptors and Inhibitors of Glycine Transporter 2”
    • Authors: Casey I. Gallagher, Zachary J. Frangos, Diba Sheipouri, Susan Shimmon, Meryem-Nur Duman, Srinivasan Jayakumar, Christopher L. Cioffi, Tristan Rawling, Robert J. Vandenberg
    • Published: ACS Chem. Neurosci. 2023, 14, 15, 2634–2647
    • DOI: 10.1021/acschemneuro.3c00167

 

  • “Bis(Benzofuran–1,3-N,N-heterocycle)s as Symmetric and Synthetic Drug Leads against Yellow Fever Virus.”
    • Authors: Nitesh K. Gupta, Srinivasan Jayakumar, Wen-Chieh Huang, Pieter Leyssen, Johan Neyts, Sergey O. Bachurin, Jih Ru Hwu, Shwu-Chen Tsay
    • Published: Int. J. Mol. Sci. 2022, 23, 12675.
    • DOI: 10.3390/ijms232012675

 

  • “Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction: Potential Novel Therapeutics for Macular Degeneration, Transthyretin Amyloidosis, and Their Common Age-Related Comorbidities.”
    • Authors: Christopher L. Cioffi, Arun Raja, Parthasarathy Muthuraman, Aravindan Jayaraman, Srinivasan Jayakumar, Andras Varadi, Boglarka Racz, Konstantin Petrukhin
    • Published: J. Med. Chem. 2021, 64, 13, 9010−9041.
    • DOI: 10.1021/acs.jmedchem.1c00099

 

  • “Enterovirus Inhibition by Hinged Aromatic Compounds with Polynuclei.”
    • Authors: Jih Ru Hwu, Avijit Panja, Srinivasan Jayakumar, Shwu-Chen Tsay, Kui-Thong Tan, WenChieh Huang, Yu-Chen Hu, Pieter Leyssen, Johan Neyts
    • Published: Molecules 2020, 25, 3821.
    • DOI: 10.3390/molecules25173821

 

  • “Synthesis and Human Anticancer Cell Line Studies on Coumarin- −carboline Hybrids as Possible Antimitotic Agents.”
    • Authors: S. Samundeeswari, Manohar V. Kulkarni, Shrinivas D. Joshi, Sheshagiri R. Dixit, Srinivasan Jayakumar, R. M. Ezhilarasi
    • Published: ChemistrySelect 2016, 1, 50195024.
    • DOI: 10.1002/slct.201601020

 

 

Beom Jin Kim | Organic Chemistry | Best Researcher Award

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 Dr. Beom Jin Kim | Organic Chemistry | Best Researcher Award

 

👨‍🏫Professional Profile 🌟

🔬 With a rich nine-year background in advanced energy storage materials, I specialize in pioneering electrode materials and systems for cutting-edge batteries beyond lithium-ion. My expertise spans the synthesis and modification of electrode materials using diverse chemical and solid-state approaches. Proficient in assessing electrochemical performance through various techniques, I excel in characterizing materials using in-situ and ex-situ spectroscopic methods. Currently immersed in anode-free all-solid-state lithium battery systems, cathode materials, anode materials, and superionic conductors, I am poised to bring my valuable knowledge and skills to elevate any project or position within your esteemed organization. ⚡🔍 #EnergyStorage #MaterialsScience #BatteryInnovation #Electrochemistry.

🌐 Professional Profiles

 

🎓Academic Background

Assistant Professor, Department of Chemistry, University of Ulsan, Ulsan, Republic of Korea (September, 2020- Present), Postdoctoral Fellow, Department of Chemistry, Brandeis University, Waltham, Massachusetts, USA (February, 2019- July, 2020). Advisor: Professor Bing Xu, Postdoctoral Fellow, Department of Chemistry, KAIST, Daejeon, Republic of Korea (March, 2018-January 2019). Advisor: Professor Insung S. Choi, Ph.D. in Organic Chemistry, Department of Chemistry, KAIST, Daejeon, Republic of Korea (February, 2018). Advisor: Professor Insung S. Choi, B.S. in Chemistry, Department of Chemistry, Sungkyunkwan University, Suwon, Republic of Korea (February, 2012)

🏆Awards and Honors

Review Editor of Frontiers in Chemistry (March, 2023-Present), Early Career Research (ECR) Board Member of Materials Today Bio (June, 2022-Present), KAIST Best Ph.D. Thesis Award (2018, KAIST), Selected as Rising Researcher (2017, Inter-Academy Seoul Science Forum, KAST), Hyocheon Scholarship (2011, Sungkyunkwan University), Academic Scholarship (2009, 2011; Sungkyunkwan University)

📚Top Noted Publication

Chemical Degradation of Various Organic Coatings via UV-Generated Sulfate Radicals. Baskoro, G. A.†; Christstardy, Y. Y.†; Rho, J.; Kim, B. J.* Chem. Asian J. 2024, accepted.

 

Thermoresponsive Maleimide-Containing Polymers with Tunable Emission for Temperature-Dependent Intracellular Imaging. Sharma, R.; Vijay, N.; Kim, B. J.; Lee, H. Eur. Polym. J. 2023, 201, 112545.

 

An Exploration of Multiple Component Peptide Assemblies by Enzyme‐Instructed Self‐Assembly. Shy, A. N.; Xu, J.; Kim, B. J.; Xu, B.* ChemSystemsChem 2023, 5, e202200041.

 

Cytoprotection of Probiotic Lactobacillus acidophilus with Artificial Nanoshells of Nature-Derived Eggshell Membrane Hydrolysates and Coffee Melanoidins in Single-Cell Nanoencapsulation. Han, S. Y.; Nguyen, D. T.; Kim, B. J.; Kim, N.; Kang, E. K.; Park, J. H.; Choi, I. S. Polymers 2023, 15, 1104.

 

Hydrogen Bonding-Based Layer-by-Layer Assembly of Nature-Derived Eggshell Membrane Hydrolysates and Coffee Melanoidins in Single-Cell Nanoencapsulation. Han, S. Y.; Yun, G.; Nguyen, D. T.; Kang, E. K.; Lee, H.; Kim, S.; Kim, B. J.; Park, J. H.; Choi, I. S.* ChemNanoMat 2022, 8, e202100535. Cover Article

 

Enzyme-Instructed Self-Assembly of Peptides: From Concept to Representative Applications. Kim, B. J.* Chem. Asian J. 2022, 17, e202200094. Invited Review

 

Enzyme-Mediated Kinetic Control of Fe3+-Tannic Acid Complexation for Interface Engineering. Lee, H.; Nguyen, D. T.; Kim. N.; Han, S. Y.; Hong, Y. J.; Yun, G.; Kim, B. J.; Choi, I. S. ACS Appl. Mater. Interfaces. 2021, 13, 52385-52394.

 

Enzyme-Mediated Film Formation of Melanin-Like Species from orthoDiphenols: Application to Single-Cell Nanoencapsulation. Kim, N.†; Lee, H. J.†; Han, S. Y.; Kim, B. J.; Choi, I. S. Appl. Surf. Sci. Adv. 2021, 5, 100098.

 

A Decade of Advances in Single-Cell Nanocoating for Mammalian Cells. Lee, H. J.; Kim, N.; Kim, B. J.; Park, J. H.; Choi, I. S.* Adv. Healthcare Mater. 2021, 10, 2100347.

 

Enzymatically Forming Cell Compatible Supramolecular Assemblies of Tryptophan-Rich Short Peptides. Yang, D.; Kim, B. J.; He, H.; Xu, B.* Pept. Sci. 2021, 113, e24173.

 

Peptide Assemblies Mimicking Chaperones for Protein Trafficking. Yang, D.; He, H.; Kim, B. J.; Xu, B.* Bioconjugate Chem. 2021, 32, 502-506.

 

Trypsin-Instructed Self-Assembly on Endoplasmic Reticulum for Selectively Inhibiting Cancer Cells. Kim, B. J.; Fang, Y.; He, H.; Xu, B.* Adv. Healthcare Mater. 2021, 10, 2000416.

 

The Ratio of Hydrogelator and Precursor Controls Enzymatic Hydrogelation of a Branched Peptide. Guo, J.; He. H.; Kim, B. J.; Wang, J.; Yi, M.; Xu, B.* Soft Matter, 2020, 16, 10101-10105.

 

 

Eusebio Juaristi | Quimica Organica | Excellence in Research

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Prof Dr. Eusebio Juaristi, Quimica Organica, Excellence in Research

Professor at CINVESTAV-IPN, Mexico

Summary

Prof. Dr. Eusebio Juaristi is a highly accomplished scientist and academic with expertise in the fields of chemistry and molecular biology. He pursued his postgraduate studies, earning a Doctorate in Chemistry at the University of North Carolina in Chapel Hill from September 1972 to March 1977. Prior to this, he completed his Bachelor of Chemical Sciences at the Institute of Technology and Higher Studies of Monterrey (ITESM) from February 1968 to June 1972.

Throughout his distinguished career, Dr. Juaristi has held various significant positions and contributed significantly to both academia and industry. He served as the Head of the Chemistry Department at CINVESTAV from August 2007 to May 2013 and has been involved in international collaborations as a Visiting Professor at institutions such as RWTH-Aachen in Germany and the University of California at Berkeley.

🌐 Professional Profiles

Scopus Profile

Google Scholar Profile

🎓 Education

Prof. Dr. Eusebio Juaristi completed his education with the following details:

Postgraduate Studies:

  • University: University of North Carolina in Chapel Hill, USA
  • Degree: Doctor in Chemistry
  • Duration: September 1972 to March 1977

Professional Studies:

  • Institute: Institute of Technology and Higher Studies of Monterrey (ITESM)
  • Degree: Bachelor of Chemical Sciences
  • Duration: February 1968 to June 1972
  • Grade Examination: August 1974

Preparatory Studies:

  • School: Irapuato Preparatory School
  • Duration: February 1966 to December 1967

Primary and Secondary Studies:

Institutes:

  • “Marciano Tinajero y Estrada” Institute, Querétaro, 1957-1962
  • “Villa Estela” Institute, Tlaxcala, 1963-1964
  • “Juan Ponce de León” Institute, Puebla, 1965

🔬 Professional Experiences

Prof. Dr. Eusebio Juaristi has a rich and extensive professional experience:

Head of Chemistry Department, CINVESTAV:

  • Duration: August 7, 2007, to May 31, 1013.

Visiting Professorships:

  • Institute of Organic Chemistry, Technische Hochschule Aachen (RWTH-Aachen), Germany, May 1 to July 31, 2013.
  • Department of Chemistry, University of California at Berkeley, USA, August 1999 to July 2000.
  • Department of Chemistry, Eidgenössische Technische Hochschule (ETH) Zürich, Switzerland, September 1985 to August 1986, and August 1992 to August 1993.

Coordinator and Full Professor at CINVESTAV:

  • Coordinator of the peptide laboratory from July 1, 2005, to December 31, 2015.
  • Full Professor, Head of the Organic Physical Chemistry Laboratory from January 1, 1983.

Other Visiting Professor Roles:

  • University of Arizona, Tucson, AZ, and various other institutions in France, Finland, Spain, Brazil, Israel, and more.

Adjunct Professor and Academic Coordinator:

  • Adjunct Professor, Head of the Organic Physical Chemistry Laboratory from September 1, 1979, to December 31, 1982.
  • Academic Coordinator of the Department of Chemistry from May 1, 1980, to August 31, 1983.

Industrial and Research Roles:

  • Syntex Diagnostics Division (SYVA Research Inst.), Palo Alto, Calif., USA, from September 1978 to August 1979.
  • Research Associate at the University of California at Berkeley, U.S.A., from April 1977 to September 15, 1978.
  • Industrial Advisor at “Industrial Orgánica, S.A.”, Monterrey, N.L., Mexico, in various periods.

Research and Teaching Positions:

  • Research work in organic chemistry at the University of North Carolina in Chapel Hill, USA, from September 1972 to March 1977.
  • Instructor in the Analytical and Organic Chemistry Laboratory at the University of North Carolina in Chapel Hill, USA, in 1974.
  • Research work in the Chemistry Department of ITESM, Mexico, from January 1971 to June 1972.
  • Assistant Teacher at ITESM, teaching elementary organic chemistry from September 1970 to May 1972.
  • Research work at the Syntex Research Center, S.A., Mexico City, in the summer of 1970.

This comprehensive professional journey showcases Prof. Dr. Eusebio Juaristi’s extensive contributions to academia, research, and leadership in the field of chemistry.

Research Area

Prof. Dr. Eusebio Juaristi’s research area spans various aspects of organic chemistry, with a particular focus on the synthesis of organic compounds, conformational analysis, and stereochemistry. His expertise encompasses both applied and theoretical studies in the field. Some key areas of his research include:

Synthesis of Narcotics and Pharmaceutical Derivatives:

  • Prof. Juaristi has been involved in the synthesis of narcotics and pharmaceutical derivatives, contributing to the development of compounds with potential applications in the medical and pharmaceutical fields.

Conformational Analysis and Stereochemistry:

  • His work includes in-depth studies on conformational analysis and stereochemistry, exploring the three-dimensional arrangement of atoms in organic molecules. This research is crucial for understanding molecular structures and their properties.

Peptide Chemistry:

  • As the Coordinator of the peptide laboratory at CINVESTAV, Prof. Juaristi has likely been engaged in research related to peptide chemistry. Peptides play a vital role in various biological processes and have applications in medicine and biotechnology.

Chemistry of Weak Acids and Theoretical Studies:

  • Prof. Juaristi has conducted research in the chemistry of weak acids, indicating an interest in understanding the properties and behavior of these acids in chemical reactions. Theoretical studies involve computational approaches to analyze organic molecules.

Organic Physical Chemistry:

  • His role as the Head of the Organic Physical Chemistry Laboratory suggests a focus on the physical aspects of organic compounds. This may involve studying their physical properties, spectroscopy, and other characteristics.

Industrial Collaboration:

  • Prof. Juaristi’s involvement in industrial advisory roles at “Industrial Orgánica, S.A.” and Syntex Diagnostics Division reflects a connection between academic research and industrial applications, showcasing a multidisciplinary approach.

Visiting Professorships:

  • His diverse experiences as a visiting professor at various international institutions indicate collaboration and knowledge exchange on a global scale.

📚Top Noted Publication

The provided list includes selected publications by Prof. Dr. Eusebio Juaristi along with their respective citation counts:

Phosphorylation of zona occludens-2 by protein kinase Cε regulates its nuclear exportation

  • Authors: D Chamorro, L Alarcon, A Ponce, R Tapia, H González-Aguilar, …
  • Journal: Molecular Biology of the Cell
  • Year: 2009
  • Citations: 30

Diastereoselective Electrophilic Amination of Chiral 1‐Benzoyl‐2, 3, 5, 6‐tetrahydro‐3‐methyl‐2‐(1‐methylethyl) pyrimidin‐4 (1H)‐one for the Asymmetric Syntheses of α …

  • Authors: E Castellanos, G Reyes‐Rangel, E Juaristi
  • Journal: Helvetica Chimica Acta
  • Year: 2004
  • Citations: 30

Conformational analysis of 1, 3-dithian-2-yltrimethylphosphonium chloride. Origin of the SCP anomeric effect

  • Authors: E Juaristi, G Cuevas
  • Journal: Journal of the American Chemical Society
  • Year: 1993
  • Citations: 30

Catalytic enantioselective syntheses of isoxazolidin-5-ones

  • Authors: C Cabrele, O Reiser, F Lovering, J Bikker, C Humblet, F Lovering, …
  • Journal: Synthesis
  • Year: 2017
  • Citations: 29

Identification of selective and non-selective, biostable β-amino acid agonists of recombinant insect kinin receptors from the southern cattle tick Boophilus microplus and …

  • Authors: S Taneja-Bageshwar, A Strey, P Zubrzak, H Williams, G Reyes-Rangel, …
  • Journal: Peptides
  • Year: 2008
  • Citations: 29

These publications reflect Prof. Dr. Eusebio Juaristi’s contributions to various fields, including molecular biology, organic chemistry, and catalysis. The citation counts indicate the impact and recognition of these works within the scientific community.