Mr. Shivang Shukla l Pharmacy
| Young Researcher Award

The research focuses on advancing pharmacological science through multidisciplinary approaches involving drug discovery, nanotechnology, computational modeling, and translational pharmacology. Current investigations explore the computational identification of skeletal muscle-specific AMPK activators for type-2 diabetes therapy, aiming to enhance metabolic regulation and therapeutic efficacy. Additional studies examine the cardioprotective potential of Artocarpus heterophyllus against isoprenaline-induced myocardial infarction and the neuroprotective role of Coenzyme Q10 as an adjuvant to nanostructured lipid carriers loaded with Adenium obesum in ethanol-induced cognitive impairment models. The work integrates molecular biology, biochemistry, and pharmacokinetic analysis to identify novel therapeutic pathways and biomarker targets. Emphasis is also placed on nanocarrier-based drug delivery for neurological and cardiovascular disorders, focusing on improving bioavailability and site-specific targeting. Parallel research on nanotherapeutics addresses challenges in treating conditions such as Alzheimer’s disease, psoriasis, and Clostridioides difficile infection. The studies utilize a combination of in silico, in vitro, and in vivo methodologies to develop innovative solutions in pharmacology and toxicology. Through experimental validation and advanced modeling, this research contributes to understanding drug mechanisms, enhancing safety profiles, and formulating next-generation therapeutics for complex diseases, thereby supporting the global goal of precision medicine and sustainable healthcare innovation.