Kun Chang | Urological Oncology| Best Researcher Award

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Ā Dr. Kun Chang| Urological Oncology | Best Researcher Award

 

šŸ‘Øā€šŸ«Professional SummaryĀ šŸŒŸ

šŸŽ“ Ph.D. graduate in Urological Oncology with expertise in Ubiquitination and Tumorigenesis from Fudan University, Shanghai. šŸ„ Currently, an Attending Urologist at Fudan University Shanghai Cancer Center, building on a comprehensive Residency experience from July 2018 to June 2021. šŸŒ Actively engaged in groundbreaking research, exploring the mechanisms of SPOP-mediated non-degradable ubiquitination in prostate cancer. šŸ§Ŗ Passionate about advancing understanding in the field and contributing to cutting-edge studies. šŸš€ Excited to leverage skills and knowledge for further advancements in urological oncology. #UrologyExpert #ResearchInnovator

šŸŒ Professional Profiles

šŸŽ“ Ā Education & Training

Ph.D., Sep 2015 – Jun 2018 Research Interests: Urological oncology, Ubiquitination, Tumorigenesis Fudan University, Shanghai, China. State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P.R. China. M.D., Sep 2012 – Jun 2015 Research Interests: Urological oncology Fudan University, Shanghai, China

šŸ”¬ Ā Researcher & Professional Experience

Residency at Fudan University Shanghai Cancer Center, July 2018-June 2021, Attending Urologist at Fudan University Shanghai Cancer Center, July 2021-

šŸ” Charge Topic Researcher

Study on the mechanism of SPOP-mediated non-degradable ubiquitination modification of ARHGAP29 in regulating the Hippo pathway in prostate cancer. Shanghai Sailing Program (Grant No. 19YF 1408600) Study on the mechanism of SPOP-mediated ZMYND8 non-degradable ubiquitin-modification in prostate cancer to regulate DNA damage response. Natural Science Foundation of China (Grant No. 81902614)

šŸ“šTop Noted Publication

 

  • Title: Unveiling the impact of tertiary lymphoid structures on immunotherapeutic responses of clear cell renal cell carcinoma
    • Authors: W. Xu, J. Lu, X. Tian, S. Ye, S. Wei, J. Wang, A. Anwaier, Y. Qu, W. Liu, K. Chang, H. Zhang, D. Ye
    • Journal: MedComm(2020), 5 (2024) e461
    • Co-correspondence, IF: 9.9

 

 

  • Title: Plasma proteomic profiling discovers molecular features associated with upper tract urothelial carcinoma
    • Authors: Y. Qu, Z. Yao, N. Xu, G. Shi, J. Su, S. Ye, K. Chang, K. Li, Y. Wang, S. Tan, X. Pei, Y. Chen, Z. Qin, J. Feng, J. Lv, J. Zhu, F. Ma, S. Tang, W. Xu, X. Tian, A. Anwaier, S. Tian, W. Xu, X. Wu, S. Zhu, Y. Zhu, D. Cao, M. Sun, H. Gan, J. Zhao, H. Zhang, D. Ye, C. Ding
    • Journal: Cell Rep Med, 4 (2023) 101166
    • Co-first, IF: 14.3

 

 

  • Title: The expression and prognostic value of transporter 1, ATP binding cassette subfamily B member in clear cell renal cell cancer with experimental validation
    • Authors: Z.D. Wang, X. Tian, Y. Wang, J.J. Wang, S.Q. Ye, Y.Q. Huang, Y.Y. Qu, K. Chang, G.H. Shi, D.W. Ye, C.Y. Gu
    • Journal: Front Oncol, 12 (2022) 1013790
    • Co-correspondence, IF: 5.738

 

  • Title: Construction of an Immune Escape-Related Signature in Clear Cell Renal Cell Carcinoma and Identification of the Relationship between IFNAR1 and Immune Infiltration by Multiple Immunohistochemistry
    • Authors: K. Chang, F. Xu, X. Zhang, B. Zeng, W. Zhang, G. Shi, D. Ye
    • Journal: Cancers (Basel), 15 (2022)
    • Co-first, IF: 6.575

 

 

  • Title: Development and validation of a mitochondrial metabolism-associated nomogram for prediction of prognosis in clear cell renal cell carcinoma
    • Authors: B. Zeng, Y. Huang, S. Jin, X. Zhang, H. Zhang, G. Shi, D. Cao, K. Chang, B. Dai, D. Ye
    • Journal: Clin Transl Med, 10 (2020) e120
    • Co-correspondence, IF: 7.919

 

Nevena Jeremic | Pharmaceutical Chemistry | Best Researcher Award

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Assoc Prof Dr. Nevena Jeremic | Pharmaceutical Chemistry | Best Researcher Award

 

šŸ‘Øā€šŸ«Professional Profile šŸŒŸ

Driven by a passion for pharmacology and physiological sciences, I earned my Master of Pharmacy in 2012 from the University of Kragujevac, Serbia. Subsequently, I embarked on a transformative Ph.D. journey, specializing in Clinical and Experimental Pharmacology (2012-2015). My doctoral thesis focused on the impactful theme of preconditioning isolated hearts with ischemia and proton pump inhibitors, exploring their effects on cardiodynamics and coronary flow.

Engaging in various organizational roles, I actively contributed to physiological science congresses, furthering collaborative discourse. Notable involvements include the organization of the 2nd Congress of Physiological Science in Serbia and the 2nd European Section Meeting of the International Academy of Cardiovascular Sciences.

In my academic career, I started as an Assistant Trainee in the Department of Pharmaceutical Chemistry (2013-2015), progressing to Assistant and then Associate Professor roles at the University of Kragujevac. A dedicated Postdoctoral Associate at the University of Louisville, KY, USA (2016-2018), I currently serve as an Adjunct Assistant Professor, bridging my expertise between pharmaceutical chemistry and physiology. šŸŒšŸ“š #Pharmacology #PhysiologicalSciences #AcademicJourney #ResearchExcellence

šŸŒ Professional Profiles

 

šŸŽ“ Education Background

Master of Pharmacy: Year: 2012 Institution: Faculty of Medical Sciences, Department of Pharmacy, University of Kragujevac, PhD: Years: 2012-2015 Institution: Faculty of Medical Sciences, University of Kragujevac, Serbia Field: Clinical and Experimental Pharmacology Thesis: Preconditioning of isolated heart with ischemia and proton pump inhibitors: effects on cardiodynamic and coronary flow Fellowship (Residency Program): Medical Biochemistry / 4th year

šŸŒ Organizational Activities

2009: Active participant, Member of the Organizing Committee of 2nd Congress of Physiological Science of Serbia with international participation. Current trends in Physiological Science. Kragujevac, Serbia, September 17-20. 2013: Active participant, Member of the Organizing Committee of Bilateral Scientific Conference “New Frontiers in Physiological Sciences ā€“ from scientific truth via friendship to the art”, Kovacica, Serbia, June 20-23. 2014: Active participant, Member of the Organizing Committee of 3rd Congress of Physiological Sciences of Serbia with International Participation, Belgrade, Serbia, October 29-31. 2015: Active participant, Member of the Organizing Committee of 2nd European Section Meeting of the International Academy of Cardiovascular Sciences, Belgrade, Serbia, October 8-10. 2018: 4th Congress of Physiological Sciences of Serbia with International Participation: “Current Trends in Physiological Sciences: From Cell Signals to the Biology of Aging” (September 19-23, 2018, Faculty of Medicine, University of NiÅ”, NiÅ”, Republic of Serbia). 8th International Congress of Pathophysiology (satellite symposium): “OXIDATIVE STRESS IN HEALTH AND DISEASE: FROM BASIC SCIENCE TO APPLIED INVESTIGATIONS” (September 2-3, 2018, Faculty of Medical Sciences, University of Kragujevac). 2019: Third Joint Meeting of National Physiological Societies from Slovakia and Serbia “Health Risk, Nutrition and Dietary Supplements: Oxidative Stress and Polyphenols in the Heart of Serbian Wineries” (Topola – Oplenac, Serbia, June 20-22, 2019). 6th Meeting of European Section and 7th Meeting of North American Section of the IACS (Vrnjacka Banja/Serbia, September 11-14, 2019).

šŸ‘©ā€šŸ« Academic Employment

2013-2015: Assistant Trainee on Department of Pharmaceutical Chemistry, Faculty of Medical Sciences, University of Kragujevac. 2015-2017: Assistant on Department of Pharmaceutical Chemistry, Faculty of Medical Sciences, University of Kragujevac. 2017-2022: Assistant Professor, Department of Pharmaceutical Chemistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia. 2022-Present: Associate Professor, Department of Pharmaceutical Chemistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia. 2016-2018: Post Doctoral Associate, Department of Physiology, University of Louisville, KY, USA. 2018-Present: Adjunct Assistant Professor, Department of Physiology, University of Louisville, KY, USA.

šŸ† Awards

2024: The charter of the University of Saint Sava to the Center of Excellence for the study of redox balance in cardiovascular and metabolic disorders, University of Kragujevac. 2022: The best female scientist at Faculty of Medical Science according to University of Kragujevac. 2017: Travel Award 4th European Section Meeting of the International Academy of Cardiovascular Sciences, Pecs, Hungary. 2017: Meritorious Postdoctoral Fellow Poster Presentation Award ā€“ Kentucky Chapter of the American Physiological Society, Bowling Green, KY. 2016: Travel Award ā€“ 3rd European Section Meeting of the International Academy of Cardiovascular Sciences, Marseille, France.

šŸ‘„ Memberships

Member of the American Heart Association, affiliated with the Hypertension Council (Membership No. 218487890) (2016-2018). Member of Serbian Physiological Society. Member of the American Physiological Society (2016-2018).

šŸ‘©ā€šŸ”¬ Mentoring

PhD Candidate: Jovana Jeremic, MS Pharm. Thesis: Cardioprotective effects of diallyl trisulfide on ischemic-reperfusion injury of isolated rat heart with metabolic syndrome: the role of oxidative stress Date of PhD Defense: 12/27/2019 (co-mentorship with Dr. Tyagi) PhD Candidate: Dragana Stanisic, DD Thesis: Effects of probiotic (Lactobacillus Rhamnosus) on parodontopathy in mice with hyperhomocysteinemia: role of dysbiosis Date of PhD Defense: 09/24/2021 (co-mentorship with Dr. Tyagi) PhD Candidate: Marina Nikolic Thesis: The role of the combined administration of the AT 1 receptor antagonist and neprilysin inhibitor in the promotion of browning in an experimental model of the metabolic syndrome and in silico identification of signaling pathways Date of PhD Defense: in process (co-mentorship with Dr. Jakovljevic) Mentor of 9 master theses for Pharmacy students in the field of pharmaceutical chemistry.

šŸ” Reviewing

Serbian Journal of Experimental and Clinical Research. Oxidative Medicine and Cellular Longevity. Scientific Reports. Aging. Editor for Special Issue in Frontiers of Physiology.

šŸ“š Guest Editor

Pathophysiology – Special Issue “Cardiovascular Physiology and Haemodynamics: Haemodynamic Optimization”. Frontiers in Physiology – “Exercise in the Prevention and Treatment of Cardiovascular Diseases”.

šŸ“šTop Noted Publication

  1. Authors: Raicevic S, Cubrilo D, Arsenijevic S, Vukcevic G, Zivkovic V, Vuletic M, Barudzic N, Andjelkovic N, Antonovic O, and Jakovljevic V.
    • Title: Oxidative stress in fetal distress: Potential prospects for diagnosis.
    • Journal: Oxidative Medicine and Cellular Longevity 2010; 3(3): 214-8.
  2. Authors: Djordjevic D, Cubrilo D, Macura M, Barudzic N, Djuric D, Jakovljevic V.
    • Title: The influence of training status on oxidative stress in young male handball players.
    • Journal: Molecular and Cellular Biochemistry. 2011 May; 351(1-2): 251-9.
  3. Authors: Koprivica Z, Djordjevic D, Vuletic M, Zivkovic V, Barudzic N, Andjelkovic N, Djuric D, Iric-Cupic V, Krkeljic J, and Jakovljevic V.
    • Title: von Willebrand factor and oxidative stress parameters in acute coronary syndromes.
    • Journal: Oxidative Medicine and Cellular Longevity. 2011; 2011: 918312. Epub 2011 Aug 8.
  4. Authors: Djordjevic DZ, Cubrilo DG, Barudzic NS, Vuletic MS, Zivkovic VI, Nesic M, Radovanovic D, Djuric DM, Jakovljevic VLj.
    • Title: Comparison of blood pro/antioxidant levels before and after acute exercise in athletes and non-athletes.
    • Journal: General Physiology and Biophysics. 2012 Jun; 31(2): 211-9.
  5. Authors: Zivkovic V, Jakovljevic V, Djordjevic D, Vuletic M, Barudzic N, Djuric D.
    • Title: The effects of homocysteine-related compounds on cardiac contractility, coronary flow, and oxidative stress markers in isolated rat heart.
    • Journal: Molecular and Cellular Biochemistry. 2012 Nov; 370(1-2): 59-67.
  6. Authors: Djordjevic DZ, Cubrilo DG, Puzovic VS, Vuletic MS, Zivkovic VI, Barudzic NS, Radovanovic DS, Djuric DM, Jakovlevic VLj.
    • Title: Changes in athleteā€™s redox state induced by habitual and unaccustomed exercise.
    • Journal: Oxidative Medicine and Cellular Longevity. 2012; 2012: 805850. doi: 10.1155/2012/805850.
  7. Authors: Zivkovic V, Lazarevic P, Djuric D, Cubrilo D, Macura M, Vuletic M, Barudzic N, Nesic M, Jakovljevic V.
    • Title: Alteration in basal redox state of young male soccer players after a six-month training programme.
    • Journal: Acta Physiologica Hungarica. 2013 Mar; 100(1): 64-76.
  8. Authors: Barudzic N, Turjacanin-Pantelic D, Zivkovic V, Selakovic D, Srejovic I, Joksimovic J, Djuric DM, Jakovljevic VLj.
    • Title: The effects of cyclooxygenase and nitric oxide synthase inhibition on oxidative stress in isolated rat heart.
    • Journal: Molecular and Cellular Biochemistry. 2013 Sep; 381(1-2): 301-11.
  9. Authors: Zivkovic V, Jakovljevic V, Pechanova O, Srejovic I, Joksimovic J, Selakovic D, Barudzic N, Djuric DM.
    • Title: Effects of DL-Homocysteine Thiolactone on Cardiac Contractility, Coronary Flow, and Oxidative Stress Markers in the Isolated Rat Heart: The Role of Different Gasotransmitters.
    • Journal: Biomed Res Int. 2013; 2013: 318471. doi: 10.1155/2013/318471. Epub 2013 Nov 24.
  10. Authors: Mirjana Veselinovic, Nevena Barudzic, Milena Vuletic, Vladimir Zivkovic, Aleksandra Tomic-Lucic, Dragan Djuric, Vladimir Jakovljevic.
    • Title: Oxidative stress in rheumatoid arthritis patients: relationship to diseases activity.
    • Journal: Molecular and Cellular Biochemistry. 2014 Jun; 391(1-2): 225-32.