Assist. Prof. Dr. Ann-Na Cho | Neural tissue engineering | Best Researcher Award
Assistant Professor at The University of Sydney, Australia.
🎓 Education
💼 Experience
Dr. Ann-Na Cho brings a rich blend of academic and research experience across Asia and Australia. She is currently a Lecturer and Horizon Fellow at The University of Sydney’s School of Biomedical Engineering. Previously, she was a Macquarie Vice-Chancellor Research Fellow at Macquarie Medical School (2021–2023) and held a postdoctoral role at the Charles Perkins Centre, Sydney (2020–2021). Earlier in her career, she was a postdoctoral researcher and Ph.D. candidate at Yonsei University, with a visiting research stint at Duke-NUS Medical School in Singapore. Her cross-disciplinary expertise includes biomaterials, stem cell biology, neural organoids, and microfluidic systems. She has co-authored over 25 peer-reviewed journal articles, many as first author, and serves as an editorial board member and special issue guest editor for journals like Life and IJMS. She actively contributes to academic leadership and mentoring, and chairs several scientific committees within the biomedical and microfluidics research communities.
🏆 Awards and Honors
Ann-Na Cho has earned numerous national and international accolades for her research excellence. She received the 2025 University of Sydney Dean’s Award for Outstanding Research and the 2024 Vice-Chancellor Award for Early Career Researcher of the Year. Her innovative work was recognized by MIT Technology Review’s “Innovators Under 35 Asia Pacific” in 2024. She was a finalist for the Eureka Prizes, Women of Colour in STEM Innovator Award, and L’Oréal-UNESCO For Women in Science Fellowship. In 2022, she won 1st Prize in Light Microscopy Australia’s Live Cell Imaging Competition. She has chaired sessions at MicroTAS, ASBTE, and Nano Health Symposium and served as a speaker at numerous high-profile events including ICBME, NanoMed, and WBC. Dr. Cho’s work has also earned her multiple competitive research grants exceeding $6 million from prestigious funding agencies such as NHMRC, MRFF, and Dementia Australia, underscoring her leadership in the biomedical research community.
🔬 Research Focus
Dr. Cho’s research centers on engineering human brain organoids and microphysiological systems to study neurodevelopment, neurodegenerative diseases, and viral neuropathogenesis. Her work aims to mimic complex human brain environments in vitro using stem cells, decellularized matrices, and bioengineered platforms. She has developed advanced microfluidic and brain-on-chip systems that allow precise modeling of Alzheimer’s disease, cerebral venous thrombosis, and virus-induced neural damage, including COVID-19 impacts. She is pioneering efforts to integrate machine learning with 3D brain models for drug screening and precision medicine. Her team’s contributions span biomaterials, vascularized neural tissues, and soft bioelectronics, pushing the boundaries of personalized preclinical models. Notable achievements include patents on organoid culture systems and high-impact publications on neuron-glia interactions, brain fusion events, and cognitive decline mechanisms. Her interdisciplinary projects collaborate globally across academia, medicine, and biotech, placing her at the forefront of next-generation therapeutic development and translational neuroengineering.
📝Publications
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Title: Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
Year: 2021
Authors: AN Cho, Y Jin, Y An, J Kim, YS Choi, JS Lee, J Kim, WY Choi, DJ Koo, …
Citations: 311
Link: https://www.nature.com/articles/s41467-021-25030-3 -
Title: Three-dimensional electroconductive hyaluronic acid hydrogels incorporated with carbon nanotubes and polypyrrole by catechol-mediated dispersion enhance neurogenesis of human neural stem cells
Year: 2017
Authors: J Shin, EJ Choi, JH Cho, AN Cho, Y Jin, K Yang, C Song, SW Cho
Citations: 188
Link: https://pubs.acs.org/doi/10.1021/acs.biomac.7b00694 -
Title: Bioactive scaffolds for stem cell-mediated bone tissue engineering
Year: 2014
Authors: HJ Park, SJ Yu, K Yang, Y Jin, AN Cho, J Kim, B Lee, HS Yang, SG Im, …
Citations: 115
Link: https://doi.org/10.1016/j.biomaterials.2014.08.004
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Title: Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons
Year: 2018
Authors: Y Jin, JS Lee, J Kim, S Min, S Wi, JH Yu, GE Chang, AN Cho, Y Choi, …
Citations: 113
Link: https://www.nature.com/articles/s41551-018-0240-7
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Title: SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity
Year: 2023
Authors: R Martínez-Mármol, R Giordano-Santini, E Kaulich, AN Cho, M Przybyla, …
Citations: 68
Link: https://www.science.org/doi/10.1126/sciadv.adg2248
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Title: Bio-artificial tongue with tongue extracellular matrix and primary taste cells
Year: 2018
Authors: JS Lee, AN Cho, Y Jin, J Kim, S Kim, SW Cho
Citations: 64
Link: https://doi.org/10.1016/j.biomaterials.2017.12.033
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Title: Aligned brain extracellular matrix promotes differentiation and myelination of human-induced pluripotent stem cell-derived oligodendrocytes
Year: 2019
Authors: AN Cho, Y Jin, S Kim, S Kumar, H Shin, HC Kang, SW Cho
Citations: 53
Link: https://pubs.acs.org/doi/10.1021/acsami.9b03012
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Title: Thermo-responsive polymeric nanoparticles for enhancing neuronal differentiation of human induced pluripotent stem cells
Year: 2015
Authors: HI Seo, AN Cho, J Jang, DW Kim, SW Cho, BG Chung
Citations: 53
Link: https://doi.org/10.1016/j.nano.2015.06.004
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Title: Magnetic control of axon navigation in reprogrammed neurons
Year: 2019
Authors: Y Jin, J Lee, E Chung, K Yang, J Kim, J Kim, JS Lee, AN Cho, T Oh, …
Citations: 33
Link: https://pubs.acs.org/doi/10.1021/acs.nanolett.9b02045 -
Title: Organoids for advanced therapeutics and disease models
Year: 2019
Authors: S Kim, AN Cho, S Min, S Kim, SW Cho
Citations: 32
Link: https://onlinelibrary.wiley.com/doi/full/10.1002/adtp.201800087