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 Mr. Hao Chi |Electoral Studies | Best Researcher Award 

Dr. Hao Chi, MD, is affiliated with the Clinical Medical College at Southwest Medical University in Luzhou, China. With an H-index of 21 and 1069 citations, Dr. Chi is a prolific researcher focusing on programmed cell death, therapy resistance in cancers, immune microenvironment, advanced data analysis, and exosomal dynamics in tumor ecology. He has contributed to numerous high-impact journals and serves on editorial boards and as a guest editor for several scientific publications. Dr. Chi’s expertise in utilizing cutting-edge sequencing technologies and bioinformatics positions him at the forefront of cancer research and personalized medicine.

Profile

Scholar

Education 🎓

MD, Clinical Medicine
Southwest Medical University, Luzhou 646000, China

Research Experiences and Interests 🔬

Programmed Cell Death and Tumor Prognosis Investigating the mechanisms of programmed cell death and their relevance to tumor prognosis.
Publications: Frontiers in Genetics 2022, Cells 2022, Frontiers in Molecular Biosciences 2023. Molecular Mechanisms of Therapy Resistance of Cancers Studying genetic, epigenetic, and immune system factors leading to cancer cell resistance to treatments. Publications: Journal of Medical Virology 2023, Frontiers in Immunology 2023. Immune Microenvironment and Cancer Prognostication Analyzing the tumor immune microenvironment to identify prognostic markers. Publications: Frontiers in Immunology 2022, 2023. Advanced Data Analysis in Disease Applying machine learning to diagnose and prognose diseases using multi-omics data. Publications: Frontiers in Endocrinology 2022, Tumour Virus Research 2023, Frontiers in Oncology 2023. Single-Cell and High-Throughput Sequencing Technologies Utilizing sequencing technologies to explore tumor microenvironment and therapeutic responses. Publications: Frontiers in Immunology 2023, Frontiers in Molecular Biosciences 2023, Frontiers in Pharmacology 2023. Exosomal Dynamics in Tumor Ecology Investigating the role of exosomes in cancer progression and their therapeutic potential. Publications: Journal of Oncology 2022, Frontiers in Immunology 2022, 2023.

Skills 🛠️

  1. Data Analysis
    • Proficient in R language and bioinformatics for processing and visualizing patient data from TCGA, GEO, ICGC, and CGGA.
    • Integrating high-throughput sequencing data, single-cell sequencing data, and spatial transcriptome data.
  2. Cellular and Molecular Biology
    • Designing and performing cellular phenotyping experiments.
    • Cell culture and transfection.
    • Techniques: PCR, WB, IHC, transfection, MTT, Edu assay, CCK8, transwell assay, wound healing assay, colony formation assay, flow cytometry.
  3. Animal Experiments
    • In vivo experiments, including subcutaneous tumor formation, tumor tissue collection, and physiological monitoring.

Academic Positions 🧑‍🏫

  1. Editorial Board Member
    • Discover Immunity (2024)
    • BMC Cancer (2023-present)
    • Discover Oncology (2023-present)
    • iMeta (2023-present)
  2. Guest Editor
    • Discover Oncology (2024)
    • Current Protein & Peptide Science (2024)
    • Current Genomics (2024)
    • Frontiers in Immunology (2024)
    • Current Cancer Drug Targets (2024)
    • Current Gene Therapy (2024)
    • Journal of Visualized Experiments (2023)
  3. Editorial Review Board Member
    • Oncology Research (2024)
    • Technology in Cancer Research & Treatment (2024.02-present)
    • Cancer Control (2024.02-present)
  4. Reviewer
    Journals including International Journal of Surgery, European Journal of Internal Medicine, Cancer Letters, Cell Communication and Signaling, Computers in Biology and Medicine, iScience, Inflammation Research, Environmental Toxicology, Scientific Reports, Heliyon, Frontiers in Immunology, Aging, Discover Oncology, Journal of Gene Medicine, BMC Bioinformatics, BMC Medical Genomics, BMC Cancer, BMC Pulmonary Medicine, Functional & Integrative Genomics, Archives of Dermatological Research, Journal of Orthopaedic Surgery and Research, Molecular and Cellular Biochemistry, PLOS ONE, Current Pharmaceutical Design, Open Life Sciences, JOVE, Medicine, Frontiers in Pharmacology, Frontiers in Genetics, Frontiers in Oncology, Frontiers in Surgery, Frontiers in Aging Neuroscience, Frontiers in Neuroscience, Frontiers in Molecular Biosciences, Frontiers in Public Health, Gene, Journal of Cancer, Acta Oncologica, Journal of the COPD Foundation, Cell Biology International, Oncology Research, Artificial Intelligence in Medicine, Expert Opinion on Drug Safety, Pharmaceutical Biology, Experimental Cell Research, Current Drug Targets, Journal of Inflammation Research, Journal of Stroke and Cerebrovascular Diseases, iMeta, Turkish Journal of Gastroenterology, Pharmaceutical Biology, Journal of Pain Research, World Journal of Urology, International Journal of Molecular Medicine, Diabetes, Obesity and Metabolism, Annals of Medicine, Technology in Cancer Research & Treatment, Acta Psychologica, OncoTargets and Therapy.

Oral Presentations 🎤

Invited Speaker, “Guidance on University Students’ Innovation and Entrepreneurship Projects,” Scientific Research Department of Southwest Medical University, Luzhou, China, March 2023. Workshop Conductor, “Integrating High-Throughput Sequencing Data with Machine Learning,” Sino-German Laboratory at the Affiliated Hospital of Southwest Medical University, Luzhou, China, May 2023. Presenter, Summer Research Symposium, General Hospital of the People’s Liberation Army, “Integration of Modern Medicine with Acupuncture and Moxibustion Research,” Beijing, China, May 2023. Featured Speaker, Fall Research Symposium, Beijing University of Chinese Medicine, “Advances in Breast Cancer by Single Cell Sequencing,” Beijing, China, July 2023. Keynote Speaker, “Single-Cell Sequencing: Implications for Precision Medicine,” The Affiliated Hospital of Southwest Medical University, Luzhou, China, June 2023. Invited Speaker, “Multi-Omics and Machine Learning: A New Era in Disease Understanding,” Chongqing Biomarkers Committee, Chongqing, China, October 2023. Invited Speaker, “Macao University of Science and Technology (MUST) Faculty of Medicine Chinese Medicine Master Teachers Forum Meeting,” Macau University of Science and Technology, Macau, China, October 2023.

Book Publications 📚

  • Deputy Editor: Clinical Research on Chinese Medicine Treatment for Diabetes Mellitus, Shanghai Jiao Tong University Press, Shanghai, China, 2023.

Publications Top Notes 📝

  • Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC
    • Authors: H. Chi, X. Xie, Y. Yan, G. Peng, D.F. Strohmer, G. Lai, S. Zhao, Z. Xia, G. Tian
    • Journal: Frontiers in Immunology, 2022
    • Citations: 79

 

  • A novel anoikis-related gene signature predicts prognosis in patients with head and neck squamous cell carcinoma and reveals immune infiltration
    • Authors: H. Chi, P. Jiang, K. Xu, Y. Zhao, B. Song, G. Peng, B. He, X. Liu, Z. Xia, G. Tian
    • Journal: Frontiers in Genetics, 2022
    • Citations: 79

 

  • T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
    • Authors: H. Chi, S. Zhao, J. Yang, X. Gao, G. Peng, J. Zhang, X. Xie, G. Song, K. Xu
    • Journal: Frontiers in Immunology, 2023
    • Citations: 63

 

  • Identification and validation of neurotrophic factor-related gene signatures in glioblastoma and Parkinson’s disease
    • Authors: S. Zhao, H. Chi, Q. Yang, S. Chen, C. Wu, G. Lai, K. Xu, K. Su, H. Luo, G. Peng
    • Journal: Frontiers in Immunology, 2023
    • Citations: 54

 

  • Circadian rhythm-related genes index: A predictor for HNSCC prognosis, immunotherapy efficacy, and chemosensitivity
    • Authors: H. Chi, J. Yang, G. Peng, J. Zhang, G. Song, X. Xie, Z. Xia, J. Liu, G. Tian
    • Journal: Frontiers in Immunology, 2023
    • Citations: 5

 

  • Identification of copper metabolism-related subtypes and establishment of the prognostic model in ovarian cancer
    • Authors: S. Zhao, X. Zhang, F. Gao, H. Chi, J. Zhang, Z. Xia, C. Cheng, J. Liu
    • Journal: Frontiers in Endocrinology, 2023
    • Citations: 52

 

  • Cuprotosis programmed-cell-death-related lncRNA signature predicts prognosis and immune landscape in PAAD patients
    • Authors: H. Chi, G. Peng, R. Wang, F. Yang, X. Xie, J. Zhang, K. Xu, T. Gu, X. Yang
    • Journal: Cells, 2022
    • Citations: 47

 

  • IL-7: A promising adjuvant ensuring effective T cell responses and memory in combination with cancer vaccines?
    • Authors: Y. Zhao, K. Wei, H. Chi, Z. Xia, X. Li
    • Journal: Frontiers in Immunology, 2022
    • Citations: 42

 

  • Exosomes: A potential tool for immunotherapy of ovarian cancer
    • Authors: X. Gong, H. Chi, D.F. Strohmer, A.T. Teichmann, Z. Xia, Q. Wang
    • Journal: Frontiers in Immunology, 2023
    • Citations: 40

 

  • A bioinformatics-based analysis of an anoikis-related gene signature predicts the prognosis of patients with low-grade gliomas
    • Authors: S. Zhao, H. Chi, W. Ji, Q. He, G. Lai, G. Peng, X. Zhao, C. Cheng
    • Journal: Brain Sciences, 2022
    • Citations: 40

 

Hao Chi | clinical medicine | Young Scientist Award

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