Prof Dr. Ping Li | Food Microbiology | Best Researcher Award

 

šŸ‘Øā€šŸ« šŸŒ¾Ping Li Ā a distinguished researcher and academician, is currently a pivotal figure in the field of probiotics and lactic acid bacteria at Zhejiang Gongshang University in China. With a Ph.D. in Microbiology, obtained from Zhejiang University in 2009, and subsequent postdoctoral research at Florida State University, USA, they bring a wealth of international experience to their role. Since joining Zhejiang Gongshang University in 2015,Ping Li has been at the forefront of groundbreaking research, focusing on the multifaceted properties of lactic acid bacteria. Their work delves into the production of bacteriocins, vitamins, and extracellular polysaccharides by these bacteria, with a specific emphasis on their application in the food industry. As a testament to their research prowess,Ā  has secured numerous grants, notably as the project leader for projects investigating the regulatory effects and molecular mechanisms of bacteriocins on the intestinal epithelial barrier, as well as the impact of lactic acid bacteria-derived metabolites on the gastrointestinal microbiota. Their dedication to advancing knowledge in this domain is evident through leadership roles in various national and provincial science and technology projects.

 

šŸŒ Professional Profiles

Research Interests šŸ§Ŗ

Our research focuses on probiotics, particularly lactic acid bacteria, that can produce bacteriocins, vitamins, and extracellular polysaccharides, among other substances, as well as their application in the food industry. We are aiming to understand the mechanism by which bacteriocins act against foodborne pathogens, the regulation of probiotic-derived metabolites (such as bacteriocins, folate, VB12, etc.) on the gastrointestinal (GI) microbiota, and the impact of functional lactic acid bacteria on immunity.

Education and Work Experiences šŸŽ“šŸŒ

Zhejiang Gongshang University, China (2023.01-Now), Zhejiang Gongshang University, China (2017.12-Now), Zhejiang Gongshang University, China (2015.03-2017.12), Florida State University, USA (2009.10-2014.10), Zhejiang University, China (2003.09-2009.03)

Grants (where I am/was the project leader in bold) šŸ’°

[1] National Natural Science Foundation of China, Regulatory effect and molecular mechanism of a bacteriocin derived from lactic acid bacteria (Plantaricin JK) on the intestinal epithelial barrier (32272301)ļ¼Œ2023.01-2026.12. Budget: RMBļæ„550,000. [2] National Natural Science Foundation of Chinaļ¼ŒLactic acid bacteria derived 5-methyltetrahydrofolate regulates the gut microflora and its molecular mechanism (31972974)ļ¼Œ2020.01-2023.12. Budget: RMBļæ„580,000. [4] The Outstanding Young Scholars Program of Zhejiang Natural Science Foundation, Molecular mechanism of lactic acid bacteria-derived bacteriocins in regulating intestinal microbiota and inhibiting intestinal inflammation in IBD(LR22C200005)ļ¼Œ2022.01-2024.12. Budget: RMBļæ„800,000. [5] Major Science and Technology Projects of Zhejiang Province, Screening of Bacteriocin-producing lactic acid bacteria and key technologies for industrialization, 2020.01-2022.12. Budget: RMBļæ„5000,000.

Awards šŸ†

Second prize of National Science and Technology Progress Award, Functional lactic acid bacteria and the key technology of industrialization, 2019, 5/10. Second prize of Zhejiang Science and Technology Progress Award, Key technologies and industrialization of hierarchical intelligent manufacturing and steady-state application of active ingredients from Zhejiang specialty plants, 2023, 2/9. First prize of Zhejiang Science and Technology Progress Award, Application of functional Lactic acid bacteria (producing bacteriocin, B vitamins, etc.) in the dairy products, 2017, 3/12. Second prize of Science and technology innovation award of China Food Science and Technology Society, Characterization of extracellular vitamin B12 producing Lactobacillus plantarum strains and assessment of the probiotic potentials, 2017, 1/5.

Management, organization, memberships of committees šŸ¤

2023.09 Committee Member of the Academic Committee, Zhejiang Gongshang University 2023.05 Deputy Director of the Dairy Processing Committee, Zhejiang Dairy Industry Association 2022.08 Third Council Member of the Probiotics Branch, Chinese Society of Food Science and Technology 2023.09 Executive Vice President of the Green Valley Food and Health Industry Research Institute, Zhejiang Gongshang University 2022.05 Editorial Board Member of Advanced Gut & Microbiome Research 2022.01 Guest Associate Editor of the special issue ofā€œRising stars in Microbiome in Health and Disease: 2022ā€, Frontiers in Cellular and Infection Microbiology 2021.10 Guest Associate Editor of the special issue “Rising stars in Microbiome in Health and Disease: 2022” in Frontiers in Cellular and Infection Microbiology. 2021.12 Frontiers in Cellular and Infection Microbiology, Review Editor 2020.08 Committee Member of the Microbiology Professional Committee, Zhejiang Bioinformatics Society. 2019.02 Frontiers in Immunology, Review Editor

Patents šŸ“œ

A total of 11 granted invention patents have been achieved. (See the original content for detailed patent information) This content provides an overview of the researcher’s academic journey, research interests, grants, awards, and contributions to academic committees and editorial boards.

šŸ“šTop Noted Publication

Ā Bacteriocins: Crucial Guardians of the Gastrointestinal Tract. Comprehensive Reviews in Food Science and Food Safety. 2024, 23, 1-27.

Role of folic acid in regulating gut microbiota and short-chain fatty acids based on an in vitro fermentation model. Appl Microbiol Biotechnol. 2024; 108(1):1-15.

Ā Ndj1, a telomere-associated protein, regulates centrosome separation in budding yeast meiosis. J Cell Biol. 2015, 209(2):247-59.

The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis. Cell Stem Cell. 2020, 27(4):618-632.

Ā Lactobacillus plantarum ZJ316 improves the quality of Stachys sieboldii Miq. pickle by inhibiting harmful bacteria growth and degrading nitrite, promoting the gut microbiota health in vitro. Food Funct. 2022, 13(3):1551-1562.

Ā Probiotic potential of Lactiplantibacillus plantarum ZFM4 isolated from pickles and its effects on human intestinal microecology. LWT-Food Sci Technol., 2023, 184:114954.

Ā Lactiplantibacillus plantarum ZJ316-fermented milk ameliorates dextran sulfate sodium-induced chronic colitis by improving the inflammatory response and regulating intestinal microbiota. Journal of dairy science. 2023, 106(11), 7352ā€“7366.

Ā Lactobacillus plantarum ZJ316 alleviates ulcerative colitis by inhibiting inflammation and regulating short-chain fatty acid levels and the gut microbiota in a mouse model. Food Funct. 2023, 11;14(9):3982-3993.

Ā Lactiplantibacillus plantarum ZJ316 fermented milk ameliorates DSS-induced chronic colitis by improving the inflammatory response and regulating intestinal microbiota. J Dairy Sci. 2023, S0022-0302(23)00253-9.

Ā Metabolism of eriocitrin in the gut and its regulation on gut microbiota in mice. Front Microbiol. 2023, 13:1111200.

The regulation function of intestinal microbiota by folate-producing Lactiplantibacillus plantarum LZ227. J Sci Food Agric. 2023, doi: 10.1002/jsfa.12851.

Phenyl lactic acid alleviates Helicobacter pylori infection in C57BL/6 mice. Food Funct. 2023,14(11):5032-5047.

Purification, characterization, and mode of action of Sakacin ZFM225, a novel bacteriocin from Lactobacillus sakei ZFM225. Biochem Biophys Rep. 2023, 35:101494.

Ā Lactiplantibacillus plantarum ZJ316 Reduces Helicobacter pylori Adhesion and Inflammation by Inhibiting the Expression of Adhesin and Urease Genes. Mol Nutr Food Res. 2023, e2300241.

Characterization of soluble dietary fiber from citrus peels (Citrus unshiu), and its antioxidant capacity and beneficial regulating effect on gut microbiota. Int J Biol Macromol. 2023, 246:125715.

Ping Li | Food Microbiology | Women Researcher Award

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