Dr. Snigdha Singh | Medicinal Chemistry | Best Researcher Award

Dr at University of Delhi, India

I am an Assistant Professor in the Department of Chemistry at the University of Delhi and a Resident Tutor at Ambedkar Ganguly Students House for Women. My research focuses on the design and synthesis of novel compounds with biological applications, and I have substantial expertise in molecular dynamics, nanoparticle synthesis, and heterocyclic chemistry. I hold a Ph.D. from the University of Delhi, and my research has led to several peer-reviewed publications and collaborations with prestigious international institutions.

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🏛️ Current Positions

Assistant Professor Department of Chemistry, University of Delhi, India June 2023 – Present. Resident Tutor Ambedkar Ganguly Students House for Women, Delhi, India September 2023 – Present

🎓 Academic Background

Postdoctoral Research Associate Rensselaer Polytechnic Institute, Department of Chemistry and Chemical Biology March 2023 – May 2023 Advisor: Prof. Christopher Cioffi Project: “Design and Synthesis of Neuropathic Inhibitors”. Research Associate-III University of Delhi, Department of Chemistry March 2021 – December 2023 Advisor: Prof. Ramesh Chandra Project: “Design and Synthesis of nanoparticles and their biomedical application”. Guest Scientist Humboldt Universität zu Berlin, Institute for Chemistry Sep. 2022 – Dec. 2022 & Sep. 2021 – Jan. 2022 Advisor: Prof. Christoph Arenz Project: “Synthesis of potential analogs for ACER3 activity”. Ph.D. in Chemistry University of Delhi Nov. 2017 – Feb. 2021 Advisor: Prof. Ramesh Chandra Thesis: “Synthesis and Development of Novel Heterocycles and their biological evaluation”. Ph.D. Exchange Student
University of Oxford, Department of Chemistry, U.K. Dec. 2020 – Feb. 2021 Advisor: Prof. Edward Anderson Project: “Towards new treatments for Leishmaniasis and Chagas disease through Natural Product chemistry”. Ph.D. Exchange Student University of Siena, Department of Chemistry, Italy Oct. 2018 – July 2019 Advisor: Prof. Maurizio Taddei Project: “Synthesis of 8-hydroxyquinoline molecules as Hedgehog Gli-Inhibitors”. M.Sc. in Chemistry (H) University of Delhi July 2013 – July 2015 Thesis: “Microwave-Assisted Synthesis of Piperidine/Piperazine based molecules”. B.Sc. in Chemistry (H) University of Delhi July 2010 – June 2013

🏅 Awards and Fellowships

Indo-UK Newton Bhabha Scholar British Council (U.K.) for research at the University of Oxford, U.K. Dec 2020 – Feb 2021. Indo-Italy Exchange Scholarship Ministry of Human Resource Development (MHRD), India & Italian Embassy Cultural Centre Oct 2018 – June 2019. Young Scientist Travel Award International Society for the study of Xenobiotics (ISSX) July 2019. Young Scientist Award University of Chemistry and Technology, Prague Sep 2019. Senior Research Fellowship (SRF) Indian Council of Medical Research (ICMR), India Dec 2018 – Dec 2020. UGC-CSIR-NET Examination 19th All India Rank Dec 2017. Merit Fellowship Hindu College, University of Delhi For 1st position in B.Sc Chemistry

🛠️ Skills

Multi-step organic reactions, heterocyclic synthesis. Handling inert-atmospheric conditions (Schlenk-line and glovebox). Binding studies of various blood proteins with anticancer drugs. Basic Cell culture, Maintenance of cancer cell lines, MTT assay, Apoptosis. Flash Chromatography, HPLC, NMR, IR, HRMS, UV-Vis, and fluorescence measurement analysis. Microsoft Office, Origin, Chem-draw, MestReNova, Joel Delta software analysis. Writing scientific reports, publications, and research projects

Publication:📝

Title: Precisely designed NIR based conjugated framework as a solid state emitter for selective recognition of cyanide ion in solid state and cancer cells
- Journal: Journal of Photochemistry and Photobiology A: Chemistry
- Year: 2024
- DOI: 10.1016/j.jphotochem.2023.115373
- EID: 2-s2.0-85178574911
- ISSN: 10106030
- Contributors: Kiran; Ranolia, A.; Rani, P.; Joshi, G.; Kumar, R.; Kumar, S.; Kumar, P.; Singh, S.; Sindhu, J.

Title: Synthesis and characterization of Fe3O4@SiO2@PDA@Ag core–shell nanoparticles and biological application on human lung cancer cell line and antibacterial strains
- Journal: Artificial Cells, Nanomedicine, and Biotechnology
- Year: 2024 (Published on 2024-12-31)
- DOI: 10.1080/21691401.2023.2295534
- Contributors: Snigdha Singh; Tanya Goel; Aarushi Singh; Heerak Chugh; Nayanika Chakraborty; Indrajit Roy; Manisha Tiwari; Ramesh Chandra

Title: Rationally designed dual channel reversible probe for cyanide recognition in aqueous medium with solid-state sensing abilities
- Journal: Journal of Photochemistry and Photobiology A: Chemistry
- Year: 2024 (Published on 2024-08)
- DOI: 10.1016/j.jphotochem.2024.115650
- Contributors: Kiran; Anju Ranolia; Priyanka; Indu Bala; Jyoti Jangir; Snigdha Singh; Jayant Sindhu; Parvin Kumar; Devender Singh

Title: Rationally designed C-3 sulfenylated 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one based fluorescent probe for recognition of Fe3+
- Journal: Journal of Molecular Structure
- Year: 2024 (Published on 2024-04)
- DOI: 10.1016/j.molstruc.2023.137456
- Contributors: Priyanka; Payal Rani; Kiran; Ramesh Kataria; Parvin Kumar; Devender Singh; Anil Duhan; Snigdha Singh; Jayant Sindhu

Title: An expeditious on-water regioselective synthesis of novel arylidene-hydrazinyl-thiazoles as DNA targeting agents
- Journal: Bioorganic Chemistry
- Year: 2023
- DOI: 10.1016/j.bioorg.2023.106524
- EID: 2-s2.0-85152729436
- ISSN: 10902120, 00452068
- Contributors: Aggarwal, R.; Hooda, M.; Kumar, P.; Kumar, S.; Singh, S.; Chandra, R.

Title: Biological activity and structure-activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis
- Journal: RSC Medicinal Chemistry
- Year: 2023
- DOI: 10.1039/d3md00081h
- EID: 2-s2.0-85162997205
- ISSN: 26328682
- Contributors: Amaral, M.; Asiki, H.; Sear, C.E.; Singh, S.; Pieper, P.; Haugland, M.M.; Anderson, E.A.; Tempone, A.G.

Snigdha Singh | Medicinal Chemistry | Best Researcher Award