Romit Seth | Agricultural and Biological Sciences | Editorial Board Member

Dr. Romit Seth | Agricultural and Biological Sciences | Editorial Board Member

North Carolina State University | United States

Dr. Romit Seth contributions span advanced plant physiology, stress biology, functional genomics, and transcriptome-driven discovery aimed at understanding the molecular mechanisms underlying plant defense, metabolic biosynthesis, and trait evolution. Investigations into Camellia sinensis have revealed candidate genes associated with blister blight resistance, providing insights into pathogen perception, defense signaling, and transcriptional reprogramming using high-resolution RNA-seq approaches. Spatial transcriptomic analysis in Trillium govanianum identified key regulatory genes involved in the biosynthesis of steroidal saponins, offering a systems-level view of tissue-specific metabolic pathway organization and potential targets for metabolic engineering of high-value phytocompounds. Population genomics studies in carrot uncovered genetic signatures of domestication and improvement, clarifying the evolutionary origin of high-carotenoid orange carrot varieties through genome-wide analyses of selection sweeps, allele diversification, and structural variations linked to pigmentation. Additional transcriptional profiling in purple tea has illuminated the seasonal dynamics of anthocyanin degradation and leaf color transitions, demonstrating how environmental cues modulate pigment biosynthesis, transport, and stabilization pathways. Collectively, this body of research advances the understanding of plant metabolic networks, defense responses, and developmental regulation, while integrating genomics and bioinformatics to support crop improvement, stress resilience, and functional characterization of agriculturally and medicinally important species.

Featured Publications

Jayaswall, K., Mahajan, P., Singh, G., Parmar, R., Seth, R., Raina, A., et al. (2016). Transcriptome analysis reveals candidate genes involved in blister blight defense in tea (Camellia sinensis (L.) Kuntze). Scientific Reports, 6, 30412. https://doi.org/10.1038/srep30412

Singh, P., Singh, G., Bhandawat, A., Singh, G., Parmar, R., Seth, R., & Sharma, R. K. (2017). Spatial transcriptome analysis provides insights of key gene(s) involved in steroidal saponin biosynthesis in medicinally important herb Trillium govanianum. Scientific Reports, 7, 45295. https://doi.org/10.1038/srep45295

Coe, K., Bostan, H., Rolling, W., Turner-Hissong, S., Macko-Podgórni, A., et al. (2023). Population genomics identifies genetic signatures of carrot domestication and improvement and uncovers the origin of high-carotenoid orange carrots. Nature Plants. https://doi.org/10.1038/s41477-023-01489-y