Dr. Romit Seth contributions span advanced plant physiology, stress biology, functional genomics, and transcriptome-driven discovery aimed at understanding the molecular mechanisms underlying plant defense, metabolic biosynthesis, and trait evolution. Investigations into Camellia sinensis have revealed candidate genes associated with blister blight resistance, providing insights into pathogen perception, defense signaling, and transcriptional reprogramming using high-resolution RNA-seq approaches. Spatial transcriptomic analysis in Trillium govanianum identified key regulatory genes involved in the biosynthesis of steroidal saponins, offering a systems-level view of tissue-specific metabolic pathway organization and potential targets for metabolic engineering of high-value phytocompounds. Population genomics studies in carrot uncovered genetic signatures of domestication and improvement, clarifying the evolutionary origin of high-carotenoid orange carrot varieties through genome-wide analyses of selection sweeps, allele diversification, and structural variations linked to pigmentation. Additional transcriptional profiling in purple tea has illuminated the seasonal dynamics of anthocyanin degradation and leaf color transitions, demonstrating how environmental cues modulate pigment biosynthesis, transport, and stabilization pathways. Collectively, this body of research advances the understanding of plant metabolic networks, defense responses, and developmental regulation, while integrating genomics and bioinformatics to support crop improvement, stress resilience, and functional characterization of agriculturally and medicinally important species.