Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

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Dr. Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

Dr at Medical University of ÅĆ³dÅŗ, Poland

Angelika Długosz-Pokorska, born on January 15, 1990, in ÅĆ³dÅŗ, Poland, is a Research Associate at the Medical University of ÅĆ³dÅŗ, specializing in medicinal chemistry and cancer research. She leads projects on anticancer compounds, opioid analogs, and their pharmacological effects, contributing to multiple EU-funded research initiatives.

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Education šŸŽ“

Angelika holds a Ph.D. in Medicinal Chemistry from the Medical University of ÅĆ³dÅŗ, Poland, and has undergone research training at the University of Rouen, France, in neuropsychopharmacology.

Experience šŸ§‘ā€šŸ«

With over 7 years of research experience, Angelika has served as Principal Investigator and Co-investigator for numerous projects, including anticancer activity studies and pharmacological analysis of synthetic peptides and compounds. She has also supervised and mentored young researchers and students.

Awards and Honors šŸ†

Angelika has received multiple accolades, including “Skuteczna Kobieta Roku 2021” (Effective Woman of the Year) in the Science category, Rector’s Awards for outstanding publications, and a First-level Special Award for Didactic Excellence.

Research Focus šŸ”

Angelikaā€™s research focuses on the development of new hybrid anticancer agents, including those with uracil skeletons and methylene groups. Her work also explores the role of endomorphin analogs in neuroprotection and cancer treatment.

Publications šŸ“š

 

  • “Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluationā€”Part I”
    • Journal: Materials
    • Date: February 15, 2024
    • DOI: 10.3390/ma17040899
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides”
    • Journal: Pharmaceuticals
    • Date: November 4, 2023
    • DOI: 10.3390/ph16111560
    • ISSN: 1424-8247
    • Contributors: Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells”
    • Journal: Biologics: Targets and Therapy
    • Date: May 2023
    • DOI: 10.2147/btt.s405080
    • ISSN: 1177-5491
    • Contributors: Angelika Długosz-Pokorska, Renata Perlikowska, Tomasz Janecki, Anna Janecka

 

  • “Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics”
    • Journal: Materials
    • Date: March 11, 2022
    • DOI: 10.3390/ma15062068
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Joanna Pacuła-Miszewska, Angelika Długosz-Pokorska, Anna Janecka, Andrzej Wojtczak, Jacek Scianowski

 

  • “A New Hybrid Ī“-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells”
    • Journal: Molecules
    • Date: 2020
    • DOI: 10.3390/molecules25071479
    • ISSN: 1420-3049
    • Contributors: Katarzyna Gach-Janczak, Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Rafał Jakubowski, Tomasz Janecki, Jacek Szymański, Anna Janecka

 

  • “New Uracil Analog U-332 is an Inhibitor of NF-ĪŗB in 5-Fluorouracil-Resistant Human Leukemia HL-60 Cell Line”
    • Journal: BMC Pharmacology & Toxicology
    • Date: 2020
    • DOI: 10.1186/s40360-020-0397-4
    • ISSN: 1471-2210
    • Contributors: Angelika Długosz-Pokorska, Marlena Pięta, Jacek Kędzia, Tomasz Janecki, Anna Janecka

 

  • “New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents”
    • Journal: Anti-Cancer Agents in Medicinal Chemistry
    • Date: 2020
    • DOI: 10.2174/1871520619666191211104128
    • ISSN: 1871-5206
    • PMID: 31823706
    • Contributors: Angelika Długosz-Pokorska, Joanna Drogosz-Stachowicz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski, Anna Janecka

 

  • “Seleninic Acid Potassium Salts as Water-Soluble Biocatalysts with Enhanced Bioavailability”
    • Journal: Materials
    • Date: 2020
    • DOI: 10.3390/ma13030661
    • ISSN: 1996-1944
    • PMID: 32024274
    • Contributors: Magdalena Obieziurska, Agata J. Pacuła, Anna Laskowska, Angelika Długosz-Pokorska, Anna Janecka, Jacek Ścianowski

 

  • “Molecular Mechanisms of Apoptosis Induced by a Novel Synthetic Quinolinone Derivative in HL-60 Human Leukemia Cells”
    • Journal: Chemico-Biological Interactions
    • Date: April 2020
    • DOI: 10.1016/j.cbi.2020.109005
    • ISSN: 0009-2797
    • Contributors: Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Agata Jaskulska, Tomasz Janecki, Anna Janecka

 

  • “Anticancer Activity of New Ī±-Methylene-Ī“-Lactone DL-247 in Selected Cancer Cell Lines”
    • Type: Conference Paper
    • Date: 2019
    • ISBN: 978-80-907442-0-2
    • Contributors: Katarzyna Gach-Janczak, Angelika Długosz-Pokorska, Joanna Drogosz, R. Jakubowski, Jacek Szymański, Tomasz Janecki, Anna Janecka

 

 

 

MOHAMED HAMDI EL ASHAL | Biochemistry Award | Best Researcher Award

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Ā Mr . MOHAMED HAMDI EL ASHAL | Biochemistry Award | Best Researcher Award

šŸ‘Øā€šŸ«Profile Summary

Efficient and detailed oriented post doctor researcher working in the field of natural products and food chemistry especially in bee products and medicinal plants. Owing to write reviews or original papers to be published in high impacted journals.

šŸŒ Professional Profiles

 

 

Qualifications šŸ“š

Post-graduation PhD. in Biochemistry (Menoufia University) Date of graduation: 2024 Area of research: Drug discovery research, Functional Food. M.SC. in Biochemistry (Menoufia University) Date of graduation: Sep. 2019 Area of research: Drug discovery research, Functional Food Analytical Biochemistry Diploma (Menoufia University) Date of graduation: May 2014 Grade: Excellent. B.Sc. in Science, Chemistry and Botany Department (Menoufia University) Date of graduation: May 2006 Grade: Very Good (83%)

Scientific Experiences šŸ”¬

  • Gas chromatography-Mass spectrometry analysis (GC-MS).
  • Liquid chromatography-Mass spectrometry analysis (LC-MS-MS).
  • GNPS interpretation.
  • Writing scientific papers.
  • Reviewing scientific papers.

Fields of Interest šŸ§Ŗ

  • Natural Product Chemistry
  • Biochemistry
  • Food Chemistry
  • Metabolomics

Conferences šŸŒ

Annual International Conference of THE EGYPTIAN FERTILITY AND STERILITY, 2023, International Association of Surgeonsā€™ Gastroenterologists and Oncologistsā€™ 5th Meeting of IASGO Egyptian Chapter, November 2021. Oral presenter in 3rd INTERNATIONAL JSPS AAE SYMPOSIUM, September 2021. Oral presenter in the 5th International Symposium on Phytochemicals in Medicine and Food conference, China, 2021. Menoufia Diabetes Conference, February 28, 2020. HGIDA 14th Scientific Event on Pitfalls in Diagnosis of Infectious Diseases, February 26, 2020. Training Course and Symposium on Apitherapy, December 4-5, 2019. Clinical Approach to Autoimmune Liver Diseases Postgraduate Course, November 27, 2019. IASGO Egyptian Chapter 2nd Annual Meeting, November 15-17, 2018.

Workshops šŸ› ļø

American Society of Pharmacognosy webinars about most recent applications of natural products from April 2020 to November 2020. 1st GNPS User Meeting, August 2020. ‘Hands-on featuring a successful academic career’ workshop at Chemistry Department, American University of Cairo (AUC), July 2019.

Skills šŸ› ļø

Good Command of English Intensive Course in English (Intermediate II Level, 36 Hours) Final Grade: Excellent (Minufia University) Conversation Course in English (Intermediate Level, 36 Hours) Final Grade: Excellent (Minufia University). Computer Skills Excellent Experience in Computer Software (Windows, Office, Internet) ICDL Certificate. Professional Development Pharma Mini-MBA (Certificate from ACC Group – American Canadian Center) Excellence in Negotiation Workshop (Scope Office) Advanced Presentation Skills Talent Pool Course Pharmacovigilance Basic Principles Leadership Skills and Management (Harvest Academy)

 

šŸ“šTop Noted Publication

  1. Title: An updated multifaceted overview of sweet proteins and dipeptides as sugar substitutes; the chemistry, health benefits, gut interactions, and safety
    • Authors: Farag, M. A., Rezk, M. M., Elashal, M. H., El-Araby, M., Khalifa, S. A., & El-Seedi, H. R.
    • Journal: Food Research International
    • Year: 2022
    • DOI: 10.1016/j.foodres.2022.111853

 

  1. Title: Bee pollen: Clinical trials and patent applications
    • Authors: Algethami, J. S., El-Wahed, A. A. A., Elashal, M. H., Ahmed, H. R., Elshafiey, E. H., Omar, E. M., … & El-Seedi, H. R.
    • Journal: Nutrients
    • Year: 2022
    • Volume: 14
    • Issue: 14
    • DOI: 10.3390/nu14142858

 

  1. Title: Cosmetic applications of bee venom
    • Authors: El-Wahed, A. A. A., Khalifa, S. A., Elashal, M. H., Musharraf, S. G., Saeed, A., Khatib, A., … & El-Seedi, H. R.
    • Journal: Toxins
    • Year: 2021
    • Volume: 13
    • Issue: 11
    • DOI: 10.3390/toxins13110810

 

  1. Title: Bee Pollen: Current Status and Therapeutic Potential
    • Authors: Khalifa, S. A., Elashal, M. H., Yosri, N., Du, M., Musharraf, S. G., Nahar, L., & El-Seedi, H. R.
    • Journal: Nutrients
    • Year: 2021
    • Volume: 13
    • Issue: 6
    • DOI: 10.3390/nu13061876

 

  1. Title: Comprehensive overview on multiple strategies fighting COVID-19
    • Authors: Khalifa, S. A., Mohamed, B. S., Elashal, M. H., Du, M., Guo, Z., Zhao, C., & El-Seedi, H. R.
    • Journal: International Journal of Environmental Research and Public Health
    • Year: 2020
    • Volume: 17
    • Issue: 16
    • DOI: 10.3390/ijerph17165813

 

  1. Title: Recent insights into chemical and pharmacological studies of bee bread
    • Authors: Khalifa, S. A., Elashal, M., Kieliszek, M., Ghazala, N. E., Farag, M. A., Saeed, A., & El-Seedi, H. R.
    • Journal: Trends in Food Science & Technology
    • Year: 2020
    • Volume: 97
    • Pages: 300-316
    • DOI: 10.1016/j.tifs.2019.08.021

 

  1. Title: Apilarnil ameliorates Bisphenol A-induced testicular toxicity in adult male rats via improving antioxidant potency and PCNA expression
    • Authors: Mohamed H. Elashal, Aida A. Abd El-Wahed, Mostafa Abdelgaber Mohamed, Rania Hamad, Mabrouk Attia Abd Eldaim, Shaden A. M. Khalifa, Hesham R. El-Seedi, Mohamed F. AlAjmi, Bishoy El-Aarag
    • Journal: Reproductive Toxicology (accepted paper)
    • Year: 2024

 

 

Diana Samodova| Proteomics

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Dr Diana Samodova: Leading Researcher in Proteomics

šŸ‘Øā€šŸ«Ā  Diana Samodova, an Dr at the University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research, Denmark. stands as a distinguished academic and researcher in the Biochemistry.

Diana Samodova, a dedicated researcher, has traversed the intricate landscapes of molecular biology and proteomics to unravel the mysteries held within ancient proteins. Her academic odyssey commenced at the University of Latvia, where she earned a Bachelor’s in Natural Sciences and delved into the photostability of nitrofurazone.

Driven by curiosity, Diana pursued a Master of Sciences in Chemistry, investigating antiradical activity kinetics in antibacterial plant extracts. This academic foundation laid the groundwork for her Ph.D. journey at the University of Copenhagen, focusing on “Mass spectrometry technology for palaeoproteomics.

šŸŒ Professional Profiles:

 

šŸŽ“ Educational Pursuits:

  • Ph.D. Thesis: Mastery of mass spectrometry techniques for palaeoproteomics.
  • Master’s Thesis: Probing antiradical activities in diverse antibacterial plant extracts.

šŸ” Research & Expertise: Diana’s expertise spans bottom-up proteomics, peptidomics, metaproteomics, and multi-enzymatic digestion. Her postdoctoral role at the University of Copenhagen expanded her horizons into scientific project management, LC-MS/MS analysis, and exploring various software applications.

šŸ“š Noteworthy Contributions: Her contributions extend beyond the lab bench; Diana’s research has graced prestigious journals. Notable publications include elucidating the oral microbiota in type-2-diabetes, muscle fiber heterogeneity, and even ancient enamel proteome sequences, shedding light on early primate species.

šŸ† Scholarly Achievements: Recipient of esteemed scholarships like the Marie Curie ETN and EEA/Norway Grants, Diana has furthered her research while fostering international cooperation and knowledge transfer.

šŸŒ Outreach & Engagement: Beyond academia, Diana co-organized scientific symposiums, engaging with diverse audiences through laboratory experiments, hands-on activities, and scientific micro-talks, inspiring the next generation of scientists.

šŸ”¬šŸŒŸ Future Exploration: Armed with a rich tapestry of proteomic expertise, Diana Samodova continues her scientific journey, unraveling the secrets held within ancient proteins, and advancing the frontiers of molecular research.

Top Noted Publication:

Early Pleistocene enamel proteome from Dmanisi resolvesĀ Stephanorhinus phylogeny Published on 2019/10/3 Cited by 138

Enamel proteome shows thatĀ Gigantopithecus was an early diverging pongine Published on 2019/12/12 Cited by 98

Palaeoproteomic profiling of conservation layers on a 14th century Italian wall painting Published on 2018/6/18 Cited by 93

Chemical composition analysis, antimicrobial activity and cytotoxicity screening of moss extracts (moss phytochemistry) Published on 2015/9/18 Cited by 87

ProAlanase is an effective alternative to trypsin for proteomics applications and disulfide bond mapping Published on 2020/12/1 Cited by 24

Multi-technique approach for qualitative and quantitative characterization of furazidin degradation kinetics under alkaline conditions Published on Cited by 9

Anti-Bacterial Activity and Online HPLC-DPPH Based Antiradical Kinetics of Medicinal Plant Extracts of High Relevance for Cosmetics Production Published on 2018/3/5 Cited by 7

Structure and stability of racemic and enantiopure pimobendan monohydrates: on the phenomenon of unusually high stability Published on 2017/4/5 Cited by 7

Chemical characterization and in vitro evaluation of birch sap and a complex of plant extracts for potential use in cosmetic anti-ageing products. Published on 2017/1/1 Cited by 3

Rugged large volume injection for sensitive capillary LC-MS environmental monitoring Published on 2017/8/28 Cited by 2