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Ā Dr. Sadegh Babashah | Molecular Medicine | Young Scientist Award

šŸŒŸProfile Summary

šŸŒ šŸ”¬ Dr. Yonca YĆ¼zĆ¼gĆ¼llĆ¼ Karakuş, an Assistant Professor at Kocaeli University, is a dedicated researcher in Microbial Biotechnology, Biochemistry, and Structural Biology. With a Ph.D. from the Middle East Technical University, her academic journey includes impactful research stints at the University of Leeds. As the Deputy Head of the Biology Department, she plays a crucial role in academia. Recognized with honors like the RCSB PDB Poster Prize and Kocaeli University Encouragement Award, she fosters the next generation of scientists through her supervision of Ph.D. and Master students. šŸŒ±šŸ§¬

šŸŒ Professional Profiles

 

Education šŸ“š

Ph.D., Molecular Genetics Tarbiat Modares University, Tehran, Iran Sep 23, 2009 – Jan 19, 2013 Thesis: Investigation of the effects of miR-326 overexpression on Hedgehog signaling pathway activation and induction of apoptosis in chronic myeloid leukemia CD34+ stem cells. M.Sc., Cell and Molecular Biology Science and research branch, Azad University, Tehran, Iran Sep 23, 2006 – Jun 27, 2009.B.Sc., Marine Biology University of Guilan, Guilan, Iran Sep 23, 2001 – Feb 19, 2006.

Research Training šŸ§Ŗ

Associate Research Scholar, Senior Scientist Tarbiat Modares University, Iran 2014 ā€“ 2018 Investigating the microRNA-mRNA regulatory network in human cancers Studying the roles of stem cell-derived exosomes in the regulation of the tumor microenvironment Studying the therapeutic effects of Curcumin on human cancers and malignancies Postdoc Research Fellow University of Michigan, MI, USA 2023 ā€“ present

Academic Appointments šŸ‘©ā€šŸ«

Associate Professor Department of Molecular Genetics, Tarbiat Modares University, Iran 2022 ā€“ present. Assistant Professor Department of Molecular Genetics, Tarbiat Modares University, Iran 2018 ā€“ 2022.

Research Interests šŸ§¬

Studying the contribution of tumor microenvironment components to cancer progression Investigating the role of regulatory RNAs in cancer biology and characterizing the significance of extracellular RNAs in the tumor microenvironment Understanding the functional roles of exosomes in regulating tumorigenesis and progression Investigating the ability of non-coding RNAs as diagnostic and prognostic biomarkers in cancer Developing novel cancer stem cell-directed treatments, reducing therapy resistance

Part-Time Activity as Teacher and/or Supervisor šŸ“

Azad University of Pishva (2012-2013) Azad University of Pharmaceutical Sciences Branch (2013-2019) Azad University of Medical Branch (2018-2019) Azad University, Science and Research Branch (2020-2022) Azad University, Tehran North Branch (2021-2022)

Awards and Honors šŸ†

  • The countryā€™s leading young researcher in the field of Biology, Abu-Reihan Award, 2021, Academy of Sciences of Iran
  • International prize winner of the 15th Khwarizmi International Youth Award, December 2013, Tehran, Iran

Teaching Experience šŸ“–

Courses Taught:

  • Molecular Genetics for MSc students
  • Immunogenetics for MSc students
  • Bioinformatics for MSc students
  • Practical cell culture for MSc students
  • Special topics in Genetics for Ph.D. students
  • Cellular and molecular biology for Ph.D. students

Conference Presentations šŸŒ

  • More than 60 abstracts and 20 oral presentations in national and international conferences

šŸ“šTop Noted Publication

  1. Colorectal cancer-secreted exosomal circ_001422
    • Journal: J Cancer Res Clin Oncol, 2023
    • Summary: Investigates the role of exosomal circ_001422 in regulating KDR expression and activating mTOR signaling in endothelial cells by targeting miR-195-5p.
  2. The Promising Role of Non-Coding RNAs for Leukemia
    • Journal: Genes (Basel), 2023
    • Summary: Highlights the potential of non-coding RNAs as biomarkers and therapeutic targets for leukemia.
  3. Characterization and Comparison of Mesenchymal Stem Cell-Derived Exosome Isolation Methods
    • Journal: Arch Razi Inst, 2022
    • Summary: Compares methods for isolating exosomes from mesenchymal stem cells.
  4. Circulating exosomal microRNAs as Prognostic Biomarkers in Gastrointestinal Cancers
    • Journal: Cancer Cell Int, 2023
    • Summary: Systematic review and meta-analysis on exosomal microRNAs as potential prognostic biomarkers in gastrointestinal cancers.
  5. Notch Signaling Pathway in Breast Cancer
    • Journal: BMC Cancer, 2022
    • Summary: Comprehensive analysis of the Notch signaling pathway as a prognostic and gene expression profile in breast cancer.
  6. Monocytes Educated by Cancer-Associated Fibroblasts
    • Journal: J Translational Medicine, 2022
    • Summary: Explores the role of monocytes educated by cancer-associated fibroblasts in breast cancer.
  7. The Role of CircRNA/miRNA/mRNA Axis in Breast Cancer Drug Resistance
    • Journal: Front Oncol, 2022
    • Summary: Reviews the role of CircRNA/miRNA/mRNA axis in breast cancer drug resistance.
  8. Circular RNAs in Regulatory Networks of Cell Signaling Pathways in Human Cancers
    • Journal: Life Sci, 2022
    • Summary: Explores the roles of circular RNAs in regulatory networks of cell signaling pathways in human cancers.
  9. A Critical Review on Induced Totipotent Stem Cells
    • Journal: Stem Cell Res, 2022
    • Summary: Provides a critical review of induced totipotent stem cells, discussing types and methods.
  10. Strategies to Overcome the Side Effects of CAR T Cell Therapy
    • Journal: Ann N Y Acad Sci, 2022
    • Summary: Discusses strategies to overcome the side effects of chimeric antigen receptor T cell therapy
Sadegh Babashah | Molecular Medicine | Best Researcher Award

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