Kazuyoshi Tsuchiya | Bio Engineering | Best Researcher Award

Ā  Prof Dr. Kazuyoshi Tsuchiya | Bio Engineering | Best Researcher AwardĀ 

Prof Dr at Tokai University,Ā  Japan

Prof. Kazuyoshi Tsuchiya is a distinguished professor in the Department of Precision and Mechanical Engineering at Tokai University, Japan. He is also a board member of the Japan Society of Precision Engineering. With over 100 publications in peer-reviewed journals and conference proceedings, his research focuses on biocompatible microneedles, piezoelectric thin film actuators, and sensors for BioMEMS. He is particularly interested in developing sensor systems that monitor biological information, such as pH levels. Prof. Tsuchiya has accumulated twenty years of academic experience in Japanese universities, specializing in MEMS and nanotechnology, utilizing super precision machining techniques like ion beam sputtering. His expertise includes practical design and production skills for MEMS and nanotechnology.

profile:

 

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Scholar

 

šŸŽ“Education

Ph.D. in Engineering University of Warwick, UK (1995-1999) Thesis: ā€œFabrication of TiNi Shape Memory Alloy Microactuators by Ion Beam Sputter Depositionā€. Master of Engineering Tokai University, Japan (1993-1995) Thesis: ā€œImprovement of Surface Roughness by Ion Beam Sputteringā€. Bachelor of Engineering Tokai University, Japan (1989-1993) Thesis: ā€œSurface Machining for Lens by Ion Beam Sputteringā€

šŸ’¼Work Experience

Professor, Department of Precision Engineering, Micro/Nano Technology Center Tokai University, Tokyo, Japan (April 2022-Present). Professor, Precision Engineering, Micro/Nano Technology Center Tokai University, Tokyo, Japan (April 2015-March 2021). Professor, Precision Engineering Tokai University, Tokyo, Japan (April 2014-March 2015). Associate Professor, Precision Engineering Tokai University, Tokyo, Japan (April 2007-March 2014). Senior Research Fellow University of Warwick, Coventry, UK (April 2012-October 2012). Research Assistant, Bio Venture Centre Osaka Institute of Technology, Osaka, Japan (April 2001-March 2005). Research Assistant, Satellite Venture Business Laboratory Ibaraki University, Hitachi, Japan (May 1999-March 2001)

šŸ”¬Research Focus

Prof. Tsuchiyaā€™s research involves: Development of pain quantitative assessment techniques for microneedle design., Simulation and development of valveless micropumps for lab-on-a-chip applications., Quantitative assessment of biocompatibility using first principle methods., Production of titanium microneedles and PZT thin film micro actuators using ion sputtering., Design of micropumping systems for drug delivery and health monitoring.

Publication:šŸ“

  1. Title: Influence of Al Doping on the Structural, Morphological, Optical, and Gas Sensing Properties of ZnO Nanorods
    • Authors: M. Navaneethan, G. K. Mani, S. Ponnusamy, K. Tsuchiya, et al.
    • Journal: Journal of Alloys and Compounds
    • Volume: 698
    • Pages: 555-564
    • Year: 2017
    • Citations: 166

 

  1. Title: Development of Blood Extraction System for Health Monitoring System
    • Authors: K. Tsuchiya, N. Nakanishi, Y. Uetsuji, E. Nakamachi
    • Journal: Biomedical Microdevices
    • Volume: 7
    • Pages: 347-353
    • Year: 2005
    • Citations: 129

 

  1. Title: ZnO-Based Microfluidic pH Sensor: A Versatile Approach for Quick Recognition of Circulating Tumor Cells in Blood
    • Authors: G. K. Mani, M. Morohoshi, Y. Yasoda, S. Yokoyama, H. Kimura, K. Tsuchiya
    • Journal: ACS Applied Materials & Interfaces
    • Volume: 9 (6)
    • Pages: 5193-5203
    • Year: 2017
    • Citations: 74

 

  1. Title: Microneedle pH Sensor: Direct, Label-Free, Real-Time Detection of Cerebrospinal Fluid and Bladder pH
    • Authors: G. K. Mani, K. Miyakoda, A. Saito, Y. Yasoda, K. Kajiwara, M. Kimura, K. Tsuchiya
    • Journal: ACS Applied Materials & Interfaces
    • Volume: 9 (26)
    • Pages: 21651-21659
    • Year: 2017
    • Citations: 64

 

  1. Title: Development of an Acetone Sensor Using Nanostructured Coā‚ƒOā‚„ Thin Films for Exhaled Breath Analysis
    • Authors: P. Srinivasan, A. J. Kulandaisamy, G. K. Mani, K. J. Babu, K. Tsuchiya, et al.
    • Journal: RSC Advances
    • Volume: 9 (52)
    • Pages: 30226-30239
    • Year: 2019
    • Citations: 50

 

  1. Title: Development of RF Magnetron Sputtering Method to Fabricate PZT Thin Film Actuator
    • Authors: K. Tsuchiya, T. Kitagawa, E. Nakamachi
    • Journal: Precision Engineering
    • Volume: 27 (3)
    • Pages: 258-264
    • Year: 2003
    • Citations: 50

 

  1. Title: Investigation on CHā‚„ Sensing Characteristics of Hierarchical Vā‚‚Oā‚… Nanoflowers Operated at Relatively Low Temperature Using Chemiresistive Approach
    • Authors: V. Mounasamy, G. K. Mani, D. Ponnusamy, K. Tsuchiya, P. R. Reshma, et al.
    • Journal: Analytica Chimica Acta
    • Volume: 1106
    • Pages: 148-160
    • Year: 2020
    • Citations: 48

 

  1. Title: Design and Development of a Biocompatible Painless Microneedle by the Ion Sputtering Deposition Method
    • Authors: K. Tsuchiya, S. Jinnin, H. Yamamoto, Y. Uetsuji, E. Nakamachi
    • Journal: Precision Engineering
    • Volume: 34 (3)
    • Pages: 461-466
    • Year: 2010
    • Citations: 48

 

  1. Title: Development and Fluidic Simulation of Microneedles for Painless Pathological Interfacing with Living Systems
    • Authors: S. Chakraborty, K. Tsuchiya
    • Journal: Journal of Applied Physics
    • Volume: 103 (11)
    • Year: 2008
    • Citations: 40

 

Dana Laor | Molecular Biology, | Best Researcher Award

Dr. Dana Laor | Molecular Biology| Best Researcher Award

šŸ‘Øā€šŸ«Profile Summary

Dr. Dana Laor Bar-Yosef is a distinguished molecular biologist renowned for her groundbreaking research in metabolic disorders. She completed her undergraduate studies in biology at the Hebrew University of Jerusalem, followed by M.Sc. and Ph.D. training at Tel Aviv University under Prof. Martin Kupiec. Her Ph.D. research elucidated the roles of TOR protein kinase in cell signaling and amino acid homeostasis using yeast models. Joining Prof. Ehud Gazit’s lab in 2015, she established innovative in vivo models for studying inborn errors of metabolism (IEMs), leading to significant insights and potential therapeutics. Dr. Laor Bar-Yosef’s expertise spans over 15 years, guiding her leadership of the metabolic research group and pioneering the concept of “Metabolostasis.” Her contributions have been recognized with prestigious awards, including the 2020 Ziegler Award, affirming her exceptional impact on medical research in metabolic disorders.

šŸŒ Professional Profiles

EducationšŸŽ“

Postdoctoral Researcher in Molecular Biology and Nanotechnology Tel Aviv University, Tel Aviv 2015-2018, Ph.D. in Molecular Biology
Tel Aviv University, Tel Aviv 2009-2014 Thesis title: “The role of TOR in rapamycin response in the fission yeast” Advisors: Prof. Martin Kupiec and Prof. Ronit Weisman. M.Sc. in Genetics Tel Aviv University, Tel Aviv 2007-2009 Thesis title: “The TOR pathway regulates cellular growth, gene silencing and telomere length maintenance in the fission yeast” Advisors: Prof. Martin Kupiec and Prof. Ronit Weisman. B.Sc. in Biology
The Hebrew University, Jerusalem 2003-2006

šŸ”¬ Researcher Experience

Head of the Metabolic Research Group Shmunis School of Biomedicine and Cancer Research, Tel Aviv University 2018-Present, Postdoctoral Research School of Molecular Cell Biology and Biotechnology, Tel Aviv University 2015-2018, Graduate Research Department of Microbiology and Biotechnology, Tel Aviv University 2007-2014

Ā Professional DevelopmentĀ  šŸ“ˆ

Women Executive Launchpad in HealthTech 8400 Health Network 2022-2023, Health Care Technological Innovation – From Idea to Commercialization Coller School of Management at Tel-Aviv University and Lahav Executive Education 2022

Ā Teaching ExperiencešŸ“š

Instructor, Introduction to Biology Course Tel Aviv University 2023-2024,Ā  Instructor, “Commercializing University Research” Course
Coller School of Management, Tel Aviv University 2020, Instructor, “Graduate Record Examination Preparation Course”
Tel Aviv University 2014-2015, Teaching Assistant, “Introduction to Genetics” Course Tel Aviv University 2007-2013

Awards šŸ†

The Late Breaking News Awards at the 2023 SSIEM Symposium 2023, The Ziegler Award for Research in the Field of Metabolic Disorders
2020, The Herbert and Sharon Glazer Fund Excellence Award 2017 And more…

Funding AcquiredšŸ’°

The John Templeton Foundation Research Grant 2021-2024, Israel Science Foundation Research Grant 2019-2023, Momentum Fund Investment in Promising Breakthrough Technologies 2021-2023 And more…

Ā PatentsšŸ› ļø

Laor, D., & Gazit, E (2018). Integrated drug discovery platform for inborn error of metabolism disorders.
US Provisional Patent Application No. 62/779,054. Pending. Laor, D., Sade, D., and Gazit, E (2021). Integrated drug discovery platform for protein misfolding disorders associated with metabolite accumulation.
Provisional.

Ā Conference and Scientific MeetingsšŸŒ

The first Metabolostasis conference, Israel (2023) Organizing Committee, ILASOL 36th Annual Meeting, Israel (2023)
Organizing Committee and Chair, Rare Connections 2022, Israel A conference dedicated for potential collaborations in the field of rare diseases. ISM 2022 Annual Meeting, Israel The first Israel Metabolomics Meeting, Israel (2022) And more…

Ā Community InvolvementšŸ‘„

Instructor, Jewish Community Center (JCC), Ohio, USA (2002, 2003) Guided Jewish-American youth about the Israeli Culture in a youth summer camp. Armor Instructor, Israel Defense Forces (2000-2002) Served as an armor guide for regular service and reserve duty soldiers at the Armored Corps School. Counselor, ā€œMaccabi Tzairā€ Youth Movement, Israel (1996-2000) Served as a counselor and teaching coordinator, mentoring and advocating Israeli youth.

šŸ“šTop Noted Publication

  1. TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions
    • Authors: M Schonbrun, D Laor, L LĆ³pez-Maury, J BaĢˆhler, M Kupiec, R Weisman
    • Journal: Molecular and cellular biology
    • Volume: 29
    • Issue: 16
    • Pages: 4584-4594
    • Citations: 72
    • Year: 2009

 

  1. Two Decades of Studying Functional Amyloids in Microorganisms
    • Authors: SA Levkovich, E Gazit, D Laor Bar-Yosef
    • Journal: Trends in Microbiology
    • Citations: 68
    • Year: 2021

 

  1. Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation
    • Authors: D Laor, D Sade, S Shaham-Niv, D Zaguri, M Gartner, V Basavalingappa, …
    • Journal: Nature communications
    • Volume: 10
    • Issue: 1
    • Pages: 62
    • Citations: 54
    • Year: 2019

 

  1. Yeast models for the study of amyloid-associated disorders and development of future therapy
    • Authors: S Rencus-Lazar, Y DeRowe, H Adsi, E Gazit, D Laor
    • Journal: Frontiers in Molecular Biosciences
    • Volume: 6
    • Pages: 15
    • Citations: 45
    • Year: 2019

 

  1. TORC1 regulates developmental responses to nitrogen stress via regulation of the GATA transcription factor Gaf1
    • Authors: D Laor, A Cohen, M Kupiec, R Weisman
    • Journal: MBio
    • Volume: 6
    • Issue: 4
    • Citations: 33
    • Year: 2015
  1. Engineered riboswitch nanocarriers as a possible disease-modifying treatment for metabolic disorders
    • Authors: S Zilberzwige-Tal, D Gazit, H Adsi, M Gartner, R Behl, D Bar-Yosef Laor, …
    • Journal: ACS nano
    • Volume: 16
    • Issue: 8
    • Pages: 11733-11741
    • Citations: 3
    • Year: 2022

 

  1. Integrated drug discovery platform for inborn error of metabolism disorders
    • Authors: E Gazit, L Dana
    • Patent: US Patent App. 17/345,248
    • Citations: 1
    • Year: 2021

 

  1. Mind your marker: the effect of common auxotrophic markers on complex traits in yeast
    • Authors: K Kaplan, SA Levkovich, Y DeRowe, E Gazit, D Laor Barā€Yosef
    • Journal: The FEBS Journal
    • Year: 2024

 

  1. The von Hippel-Lindau protein forms fibrillar amyloid assemblies that are mitigated by the anti-amyloid molecule Purpurin
    • Authors: V Kumar, V Kaushik, S Kumar, SA Levkovich, P Gupta, DL Bar-Yosef, …
    • Journal: Biochemical and Biophysical Research Communications
    • Volume: 690
    • Pages: 149250
    • Year: 2024

 

  1. Branched-Chain Amino Acid Assembly into Amyloid-like Fibrils Provides a New Paradigm for Maple Syrup Urine Disease Pathology
    • Authors: T Kreiser, I Sogolovsky-Bard, D Zaguri, S Shaham-Niv, D Laor Bar-Yosef, …
    • Journal: International Journal of Molecular Sciences
    • Volume: 24
    • Issue: 21
    • Pages: 15999
    • Year: 2023