Snigdha Singh | Medicinal Chemistry | Best Researcher Award

Ā Dr. Snigdha Singh | Medicinal Chemistry | Best Researcher Award

Dr at University of Delhi, India

I am an Assistant Professor in the Department of Chemistry at the University of Delhi and a Resident Tutor at Ambedkar Ganguly Students House for Women. My research focuses on the design and synthesis of novel compounds with biological applications, and I have substantial expertise in molecular dynamics, nanoparticle synthesis, and heterocyclic chemistry. I hold a Ph.D. from the University of Delhi, and my research has led to several peer-reviewed publications and collaborations with prestigious international institutions.

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šŸ›ļø Current Positions

Assistant Professor Department of Chemistry, University of Delhi, India June 2023 ā€“ Present. Resident Tutor Ambedkar Ganguly Students House for Women, Delhi, India September 2023 ā€“ Present

šŸŽ“ Academic Background

Postdoctoral Research Associate Rensselaer Polytechnic Institute, Department of Chemistry and Chemical Biology March 2023 ā€“ May 2023 Advisor: Prof. Christopher Cioffi Project: ā€œDesign and Synthesis of Neuropathic Inhibitorsā€. Research Associate-III University of Delhi, Department of Chemistry March 2021 ā€“ December 2023 Advisor: Prof. Ramesh Chandra Project: ā€œDesign and Synthesis of nanoparticles and their biomedical applicationā€. Guest Scientist Humboldt UniversitƤt zu Berlin, Institute for Chemistry Sep. 2022 ā€“ Dec. 2022 & Sep. 2021 ā€“ Jan. 2022 Advisor: Prof. Christoph Arenz Project: ā€œSynthesis of potential analogs for ACER3 activityā€. Ph.D. in Chemistry University of Delhi Nov. 2017 ā€“ Feb. 2021 Advisor: Prof. Ramesh Chandra Thesis: ā€œSynthesis and Development of Novel Heterocycles and their biological evaluationā€. Ph.D. Exchange Student
University of Oxford, Department of Chemistry, U.K. Dec. 2020 ā€“ Feb. 2021 Advisor: Prof. Edward Anderson Project: ā€œTowards new treatments for Leishmaniasis and Chagas disease through Natural Product chemistryā€. Ph.D. Exchange Student University of Siena, Department of Chemistry, Italy Oct. 2018 ā€“ July 2019 Advisor: Prof. Maurizio Taddei Project: ā€œSynthesis of 8-hydroxyquinoline molecules as Hedgehog Gli-Inhibitorsā€. M.Sc. in Chemistry (H) University of Delhi July 2013 ā€“ July 2015 Thesis: ā€œMicrowave-Assisted Synthesis of Piperidine/Piperazine based moleculesā€. B.Sc. in Chemistry (H) University of Delhi July 2010 ā€“ June 2013

šŸ… Awards and Fellowships

Indo-UK Newton Bhabha Scholar British Council (U.K.) for research at the University of Oxford, U.K. Dec 2020 ā€“ Feb 2021. Indo-Italy Exchange Scholarship Ministry of Human Resource Development (MHRD), India & Italian Embassy Cultural Centre Oct 2018 ā€“ June 2019. Young Scientist Travel Award International Society for the study of Xenobiotics (ISSX) July 2019. Young Scientist Award University of Chemistry and Technology, Prague Sep 2019. Senior Research Fellowship (SRF) Indian Council of Medical Research (ICMR), India Dec 2018 ā€“ Dec 2020. UGC-CSIR-NET Examination 19th All India Rank Dec 2017. Merit Fellowship Hindu College, University of Delhi For 1st position in B.Sc Chemistry

šŸ› ļø Skills

Multi-step organic reactions, heterocyclic synthesis. Handling inert-atmospheric conditions (Schlenk-line and glovebox). Binding studies of various blood proteins with anticancer drugs. Basic Cell culture, Maintenance of cancer cell lines, MTT assay, Apoptosis. Flash Chromatography, HPLC, NMR, IR, HRMS, UV-Vis, and fluorescence measurement analysis. Microsoft Office, Origin, Chem-draw, MestReNova, Joel Delta software analysis. Writing scientific reports, publications, and research projects

Publication:šŸ“

 

  • Title: Precisely designed NIR based conjugated framework as a solid state emitter for selective recognition of cyanide ion in solid state and cancer cells
    • Journal: Journal of Photochemistry and Photobiology A: Chemistry
    • Year: 2024
    • DOI: 10.1016/j.jphotochem.2023.115373
    • EID: 2-s2.0-85178574911
    • ISSN: 10106030
    • Contributors: Kiran; Ranolia, A.; Rani, P.; Joshi, G.; Kumar, R.; Kumar, S.; Kumar, P.; Singh, S.; Sindhu, J.

 

  • Title: Synthesis and characterization of Fe3O4@SiO2@PDA@Ag coreā€“shell nanoparticles and biological application on human lung cancer cell line and antibacterial strains
    • Journal: Artificial Cells, Nanomedicine, and Biotechnology
    • Year: 2024 (Published on 2024-12-31)
    • DOI: 10.1080/21691401.2023.2295534
    • Contributors: Snigdha Singh; Tanya Goel; Aarushi Singh; Heerak Chugh; Nayanika Chakraborty; Indrajit Roy; Manisha Tiwari; Ramesh Chandra

 

  • Title: Rationally designed dual channel reversible probe for cyanide recognition in aqueous medium with solid-state sensing abilities
    • Journal: Journal of Photochemistry and Photobiology A: Chemistry
    • Year: 2024 (Published on 2024-08)
    • DOI: 10.1016/j.jphotochem.2024.115650
    • Contributors: Kiran; Anju Ranolia; Priyanka; Indu Bala; Jyoti Jangir; Snigdha Singh; Jayant Sindhu; Parvin Kumar; Devender Singh

 

  • Title: Rationally designed C-3 sulfenylated 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one based fluorescent probe for recognition of Fe3+
    • Journal: Journal of Molecular Structure
    • Year: 2024 (Published on 2024-04)
    • DOI: 10.1016/j.molstruc.2023.137456
    • Contributors: Priyanka; Payal Rani; Kiran; Ramesh Kataria; Parvin Kumar; Devender Singh; Anil Duhan; Snigdha Singh; Jayant Sindhu

 

  • Title: An expeditious on-water regioselective synthesis of novel arylidene-hydrazinyl-thiazoles as DNA targeting agents
    • Journal: Bioorganic Chemistry
    • Year: 2023
    • DOI: 10.1016/j.bioorg.2023.106524
    • EID: 2-s2.0-85152729436
    • ISSN: 10902120, 00452068
    • Contributors: Aggarwal, R.; Hooda, M.; Kumar, P.; Kumar, S.; Singh, S.; Chandra, R.

 

  • Title: Biological activity and structure-activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis
    • Journal: RSC Medicinal Chemistry
    • Year: 2023
    • DOI: 10.1039/d3md00081h
    • EID: 2-s2.0-85162997205
    • ISSN: 26328682
    • Contributors: Amaral, M.; Asiki, H.; Sear, C.E.; Singh, S.; Pieper, P.; Haugland, M.M.; Anderson, E.A.; Tempone, A.G.

 

Saloni Tandon | Life sciences | Best Researcher Award

Ā Ms. Saloni Tandon | Life sciences | Best Researcher Award

šŸ‘Øā€šŸ«Profile Summary

With a B.Tech + M.Tech Dual Degree in Biotechnology from the Centre for Converging Technologies, University of Rajasthan, and a stellar score of 95%, I possess a comprehensive understanding of Biotechnology, Nanotechnology, Neurosciences, Information Technology, and Entrepreneurship. As a Research Associate at Celebal Technologies Pvt. Ltd., I spearheaded the establishment of the BioTech Research department, focusing on healthcare research and applications. My expertise lies in developing AI-based solutions for precision oncology and microsatellite identification tools. I have a proven track record of successful projects, including an end-to-end cloud-based solution for precision oncology. Additionally, my research contributions include papers on tumor detection and tissue engineering applications.

šŸŒ Professional Profiles

 

 

 

Education

B.Tech + M.Tech Dual Degree (Biotechnology), Centre for Converging Technologies, University of Rajasthan (2015 ā€“ 2020) Scored 95%. Comprehensive understanding of Biotechnology, Nanotechnology, Neurosciences, Information Technology, and Entrepreneurship.. Sangeet Bhaskar (Kathak Dance), Pracheen Kala Kendra Chandigarh, India (2018). Visharad (Kathak Dance), Bhatkhande Sangit Vidhyapith Lucknow, India (2018)

Professional Experience

Research Associate, Celebal Technologies Pvt. Ltd. (01/2022 ā€“ present) Established the BioTech Research department focusing on healthcare research and applications. Currently developing AI-based solutions for the healthcare industry. Successfully developed an end-to-end cloud-based solution for precision oncology and a microsatellite identification and instability prediction tool. Mentored and managed a team for developing an oncology-based drug sales advisory chatbot. Two research papers and two review papers related to our work are under publication. Research Intern, Defence Institute of Advanced Technology, DRDO (09/2019 ā€“ 12/2019) Worked on Polymeric Immunosensors for Tumor detection and Silk-based scaffolds for tissue engineering applications. Gained knowledge about various biomaterials. Trainee, Biotech Park (02/2018 ā€“ 03/2018) Worked on bioethanol production from agro-waste (banana peels) and leaves of Calotropis procera using Saccharomyces cerevisiae. Team Member, Centre for Converging Technologies, University of Rajasthan (01/2017 ā€“ 06/2017) Contributed to the LAMP project, developing a student information management system using HTML, PHP, and MySQL on Linux.

šŸ“šTop Noted Publication

Title: Silk-based composite scaffolds for tissue engineering applications
Authors: S Tandon, B Kandasubramanian, SM Ibrahim
Journal: Industrial & Engineering Chemistry Research
Year: 2020
Volume: 59
Issue: 40
Pages: 17593-17611
Citations: 62

Title: Advancements in hydrogel-functionalized immunosensing platforms
Authors: SM George, S Tandon, B Kandasubramanian
Journal: ACS omega
Year: 2020
Volume: 5
Issue: 5
Pages: 2060-2068
Citations: 52

Title: Polymeric immunosensors for tumor detection
Authors: S Tandon, SM George, R McIntyre, B Kandasubramanian
Journal: Biomedical Physics & Engineering Express
Year: 2020
Volume: 6
Issue: 3
Pages: 032001
Citations: 13

Title: Polyhedral Oligomeric Silsesquioxane (POSS) Polymer Nanocomposites
Authors: S Kabra, S Tandon, B Kandasubramanian, S Thomas, L Somasekharan
Publisher: Elsevier
Year: 2021
Citations: 6

Title: POSS nanocomposites for defense and space applications
Authors: S Kabra, S Tandon, B Kandasubramanian
Book: Polyhedral Oligomeric Silsesquioxane (POSS) Polymer Nanocomposites
Year: 2021
Pages: 481-498
Citations: 3

Title: A Cloud-based Precision Oncology Framework for Whole Genome Sequence Analysis
Authors: S Tandon, M Sharma, P Kasar, A Kala
Journal: Computational Biology and Chemistry
Year: 2024
Article Number: 108062