Dr. PEDRO ISMAEL DA SILVA JUNIOR | Molecular Biology |Best Researcher Award

Dr. Pedro Ismael da Silva Junior holds a degree in Biological Sciences from the Faculty of Philosophy, Sciences and Letters of Ribeirão Preto – USP (1979) and completed his Doctorate at the Institute of Biomedical Sciences-USP (2000). He currently serves as a Scientific Researcher (PqC-VI) and Manager at the Laboratory for Applied Toxinology at the Butantan Institute. Dr. da Silva specializes in Protein Chemistry, focusing on Biochemistry, with a research emphasis on bioactive molecules of toxins and hemolymph of invertebrates. His expertise includes liquid chromatography, peptide and organic molecule synthesis, mass spectrometry, and microbiology. He has published extensively and supervised numerous masters’ and doctoral theses in these areas.

profile:

🎓 Education:

Degree in Biological Sciences, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto – USP (1979). Doctorate at the Institute of Biomedical Sciences, USP (2000)

🏢 Current Position:

- Scientific Researcher (PqC-VI) and Manager at the Laboratory for Applied Toxinology, Butantan Institute

🔬 Research Interests:

Protein Chemistry, focusing on Biochemistry, Study of bioactive molecules of toxins and hemolymph of invertebrates, Antimicrobial, antiviral, and antitumoral activities, Purification, characterization, and synthesis of bioactive molecules, Techniques: liquid chromatography, peptide and organic molecule synthesis, mass spectrometry, microbiology

📚 Publications and Supervision:

Author of numerous publications, Supervisor of master’s and doctoral theses in related areas

Publication:📝

Title: The CMS experiment at the CERN LHC
Authors: CMS Collaboration
Journal: Journal of Instrumentation
Year: 2008
Volume: 3
Issue: August
Pages: 1-334
Citations: 12,546*

Title: Combined Measurement of the Higgs Boson Mass in $pp$ Collisions at $s=7\sqrt{s} = 7$ and 8 TeV with the ATLAS and CMS Experiments
Authors: CMS Collaborations
Journal: arXiv preprint arXiv:1503.07589
Year: 2015
Citations: 1,900*

Title: Performance of the CMS muon detector and muon reconstruction with proton-proton collisions at $s=13\sqrt{s} = 13$ TeV
Authors: CMS Collaboration
Journal: Journal of Instrumentation
Year: 2018
Volume: 13
Issue: 6
Article: P06015
Citations: 1,474

Title: Constraints on the spin-parity and anomalous $H VV$ couplings of the Higgs boson in proton collisions at 7 and 8 TeV
Authors: V Khachatryan, AM Sirunyan, A Tumasyan, W Adam, T Bergauer, …
Journal: Physical Review D
Year: 2015
Volume: 92
Issue: 1
Article: 012004
Citations: 1,211*

Title: Observation of $ttˉHt\bar{t}H$ Production
Authors: AM Sirunyan, A Tumasyan, W Adam, F Ambrogi, E Asilar, T Bergauer, …
Journal: Physical Review Letters
Year: 2018
Volume: 120
Issue: 23
Article: 231801
Citations: 1,063*

Title: Observation of the diphoton decay of the Higgs boson and measurement of its properties
Authors: V Khachatryan, AM Sirunyan, A Tumasyan, W Adam, T Bergauer, …
Journal: The European Physical Journal C
Year: 2014
Volume: 74
Pages: 1-49
Citations: 1,023

Title: Mapping the human genetic architecture of COVID-19
Authors: Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai …
Journal: Nature
Year: 2021
Volume: 600
Issue: 7889
Pages: 472-477
Citations: 752

Title: Precision luminosity measurement in proton–proton collisions at $s=13\sqrt{s} = 13$ TeV in 2015 and 2016 at CMS
Authors: CMS Collaboration
Journal: Springer Open
Year: 2021
Citations: 749

Title: Measurement of $ttˉt\bar{t}$ production with a veto on additional central jet activity in $pp$ collisions at $s=7\sqrt{s} = 7$ TeV using the ATLAS detector
Authors: ATLAS Collaboration
Journal: arXiv preprint arXiv:1203.5015
Year: 2012
Citations: 658

Title: Searches for third-generation squark production in fully hadronic final states in proton-proton collisions at $s=8\sqrt{s} = 8$ TeV
Authors: V Khachatryan, AM Sirunyan, A Tumasyan, W Adam, E Asilar, T Bergauer, …
Journal: Journal of High Energy Physics
Year: 2015
Volume: 2015
Issue: 6
Pages: 1-65
Citations: 584*

Dr. Dana Laor | Molecular Biology| Best Researcher Award

Profile Summary

Dr. Dana Laor Bar-Yosef is a distinguished molecular biologist renowned for her groundbreaking research in metabolic disorders. She completed her undergraduate studies in biology at the Hebrew University of Jerusalem, followed by M.Sc. and Ph.D. training at Tel Aviv University under Prof. Martin Kupiec. Her Ph.D. research elucidated the roles of TOR protein kinase in cell signaling and amino acid homeostasis using yeast models. Joining Prof. Ehud Gazit’s lab in 2015, she established innovative in vivo models for studying inborn errors of metabolism (IEMs), leading to significant insights and potential therapeutics. Dr. Laor Bar-Yosef’s expertise spans over 15 years, guiding her leadership of the metabolic research group and pioneering the concept of “Metabolostasis.” Her contributions have been recognized with prestigious awards, including the 2020 Ziegler Award, affirming her exceptional impact on medical research in metabolic disorders.

Professional Profiles

Scholar Profile

Education🎓

Postdoctoral Researcher in Molecular Biology and Nanotechnology Tel Aviv University, Tel Aviv 2015-2018, Ph.D. in Molecular Biology
Tel Aviv University, Tel Aviv 2009-2014 Thesis title: “The role of TOR in rapamycin response in the fission yeast” Advisors: Prof. Martin Kupiec and Prof. Ronit Weisman. M.Sc. in Genetics Tel Aviv University, Tel Aviv 2007-2009 Thesis title: “The TOR pathway regulates cellular growth, gene silencing and telomere length maintenance in the fission yeast” Advisors: Prof. Martin Kupiec and Prof. Ronit Weisman. B.Sc. in Biology
The Hebrew University, Jerusalem 2003-2006

🔬 Researcher Experience

Head of the Metabolic Research Group Shmunis School of Biomedicine and Cancer Research, Tel Aviv University 2018-Present, Postdoctoral Research School of Molecular Cell Biology and Biotechnology, Tel Aviv University 2015-2018, Graduate Research Department of Microbiology and Biotechnology, Tel Aviv University 2007-2014

Professional Development 📈

Women Executive Launchpad in HealthTech 8400 Health Network 2022-2023, Health Care Technological Innovation – From Idea to Commercialization Coller School of Management at Tel-Aviv University and Lahav Executive Education 2022

Teaching Experience📚

Instructor, Introduction to Biology Course Tel Aviv University 2023-2024, Instructor, “Commercializing University Research” Course
Coller School of Management, Tel Aviv University 2020, Instructor, “Graduate Record Examination Preparation Course”
Tel Aviv University 2014-2015, Teaching Assistant, “Introduction to Genetics” Course Tel Aviv University 2007-2013

Awards 🏆

The Late Breaking News Awards at the 2023 SSIEM Symposium 2023, The Ziegler Award for Research in the Field of Metabolic Disorders
2020, The Herbert and Sharon Glazer Fund Excellence Award 2017 And more…

Funding Acquired💰

The John Templeton Foundation Research Grant 2021-2024, Israel Science Foundation Research Grant 2019-2023, Momentum Fund Investment in Promising Breakthrough Technologies 2021-2023 And more…

Patents🛠️

Laor, D., & Gazit, E (2018). Integrated drug discovery platform for inborn error of metabolism disorders.
US Provisional Patent Application No. 62/779,054. Pending. Laor, D., Sade, D., and Gazit, E (2021). Integrated drug discovery platform for protein misfolding disorders associated with metabolite accumulation.
Provisional.

Conference and Scientific Meetings🌐

The first Metabolostasis conference, Israel (2023) Organizing Committee, ILASOL 36th Annual Meeting, Israel (2023)
Organizing Committee and Chair, Rare Connections 2022, Israel A conference dedicated for potential collaborations in the field of rare diseases. ISM 2022 Annual Meeting, Israel The first Israel Metabolomics Meeting, Israel (2022) And more…

Community Involvement👥

Instructor, Jewish Community Center (JCC), Ohio, USA (2002, 2003) Guided Jewish-American youth about the Israeli Culture in a youth summer camp. Armor Instructor, Israel Defense Forces (2000-2002) Served as an armor guide for regular service and reserve duty soldiers at the Armored Corps School. Counselor, “Maccabi Tzair” Youth Movement, Israel (1996-2000) Served as a counselor and teaching coordinator, mentoring and advocating Israeli youth.

📚Top Noted Publication

TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions
- Authors: M Schonbrun, D Laor, L López-Maury, J Bähler, M Kupiec, R Weisman
- Journal: Molecular and cellular biology
- Volume: 29
- Issue: 16
- Pages: 4584-4594
- Citations: 72
- Year: 2009

Two Decades of Studying Functional Amyloids in Microorganisms
- Authors: SA Levkovich, E Gazit, D Laor Bar-Yosef
- Journal: Trends in Microbiology
- Citations: 68
- Year: 2021

Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation
- Authors: D Laor, D Sade, S Shaham-Niv, D Zaguri, M Gartner, V Basavalingappa, …
- Journal: Nature communications
- Volume: 10
- Issue: 1
- Pages: 62
- Citations: 54
- Year: 2019

Yeast models for the study of amyloid-associated disorders and development of future therapy
- Authors: S Rencus-Lazar, Y DeRowe, H Adsi, E Gazit, D Laor
- Journal: Frontiers in Molecular Biosciences
- Volume: 6
- Pages: 15
- Citations: 45
- Year: 2019

TORC1 regulates developmental responses to nitrogen stress via regulation of the GATA transcription factor Gaf1
- Authors: D Laor, A Cohen, M Kupiec, R Weisman
- Journal: MBio
- Volume: 6
- Issue: 4
- Citations: 33
- Year: 2015

Engineered riboswitch nanocarriers as a possible disease-modifying treatment for metabolic disorders
- Authors: S Zilberzwige-Tal, D Gazit, H Adsi, M Gartner, R Behl, D Bar-Yosef Laor, …
- Journal: ACS nano
- Volume: 16
- Issue: 8
- Pages: 11733-11741
- Citations: 3
- Year: 2022

Integrated drug discovery platform for inborn error of metabolism disorders
- Authors: E Gazit, L Dana
- Patent: US Patent App. 17/345,248
- Citations: 1
- Year: 2021

Mind your marker: the effect of common auxotrophic markers on complex traits in yeast
- Authors: K Kaplan, SA Levkovich, Y DeRowe, E Gazit, D Laor Bar‐Yosef
- Journal: The FEBS Journal
- Year: 2024

The von Hippel-Lindau protein forms fibrillar amyloid assemblies that are mitigated by the anti-amyloid molecule Purpurin
- Authors: V Kumar, V Kaushik, S Kumar, SA Levkovich, P Gupta, DL Bar-Yosef, …
- Journal: Biochemical and Biophysical Research Communications
- Volume: 690
- Pages: 149250
- Year: 2024

Branched-Chain Amino Acid Assembly into Amyloid-like Fibrils Provides a New Paradigm for Maple Syrup Urine Disease Pathology
- Authors: T Kreiser, I Sogolovsky-Bard, D Zaguri, S Shaham-Niv, D Laor Bar-Yosef, …
- Journal: International Journal of Molecular Sciences
- Volume: 24
- Issue: 21
- Pages: 15999
- Year: 2023

PEDRO ISMAEL DA SILVA JUNIOR | Molecular Biology | Best Researcher Award

Dr. PEDRO ISMAEL DA SILVA JUNIOR | Molecular Biology |Best Researcher Award

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