Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

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Dr. Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

Dr at Medical University of ÅĆ³dÅŗ, Poland

Angelika Długosz-Pokorska, born on January 15, 1990, in ÅĆ³dÅŗ, Poland, is a Research Associate at the Medical University of ÅĆ³dÅŗ, specializing in medicinal chemistry and cancer research. She leads projects on anticancer compounds, opioid analogs, and their pharmacological effects, contributing to multiple EU-funded research initiatives.

Profile

Scopus

orcid

Education šŸŽ“

Angelika holds a Ph.D. in Medicinal Chemistry from the Medical University of ÅĆ³dÅŗ, Poland, and has undergone research training at the University of Rouen, France, in neuropsychopharmacology.

Experience šŸ§‘ā€šŸ«

With over 7 years of research experience, Angelika has served as Principal Investigator and Co-investigator for numerous projects, including anticancer activity studies and pharmacological analysis of synthetic peptides and compounds. She has also supervised and mentored young researchers and students.

Awards and Honors šŸ†

Angelika has received multiple accolades, including “Skuteczna Kobieta Roku 2021” (Effective Woman of the Year) in the Science category, Rector’s Awards for outstanding publications, and a First-level Special Award for Didactic Excellence.

Research Focus šŸ”

Angelikaā€™s research focuses on the development of new hybrid anticancer agents, including those with uracil skeletons and methylene groups. Her work also explores the role of endomorphin analogs in neuroprotection and cancer treatment.

Publications šŸ“š

 

  • “Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluationā€”Part I”
    • Journal: Materials
    • Date: February 15, 2024
    • DOI: 10.3390/ma17040899
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides”
    • Journal: Pharmaceuticals
    • Date: November 4, 2023
    • DOI: 10.3390/ph16111560
    • ISSN: 1424-8247
    • Contributors: Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells”
    • Journal: Biologics: Targets and Therapy
    • Date: May 2023
    • DOI: 10.2147/btt.s405080
    • ISSN: 1177-5491
    • Contributors: Angelika Długosz-Pokorska, Renata Perlikowska, Tomasz Janecki, Anna Janecka

 

  • “Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics”
    • Journal: Materials
    • Date: March 11, 2022
    • DOI: 10.3390/ma15062068
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Joanna Pacuła-Miszewska, Angelika Długosz-Pokorska, Anna Janecka, Andrzej Wojtczak, Jacek Scianowski

 

  • “A New Hybrid Ī“-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells”
    • Journal: Molecules
    • Date: 2020
    • DOI: 10.3390/molecules25071479
    • ISSN: 1420-3049
    • Contributors: Katarzyna Gach-Janczak, Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Rafał Jakubowski, Tomasz Janecki, Jacek Szymański, Anna Janecka

 

  • “New Uracil Analog U-332 is an Inhibitor of NF-ĪŗB in 5-Fluorouracil-Resistant Human Leukemia HL-60 Cell Line”
    • Journal: BMC Pharmacology & Toxicology
    • Date: 2020
    • DOI: 10.1186/s40360-020-0397-4
    • ISSN: 1471-2210
    • Contributors: Angelika Długosz-Pokorska, Marlena Pięta, Jacek Kędzia, Tomasz Janecki, Anna Janecka

 

  • “New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents”
    • Journal: Anti-Cancer Agents in Medicinal Chemistry
    • Date: 2020
    • DOI: 10.2174/1871520619666191211104128
    • ISSN: 1871-5206
    • PMID: 31823706
    • Contributors: Angelika Długosz-Pokorska, Joanna Drogosz-Stachowicz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski, Anna Janecka

 

  • “Seleninic Acid Potassium Salts as Water-Soluble Biocatalysts with Enhanced Bioavailability”
    • Journal: Materials
    • Date: 2020
    • DOI: 10.3390/ma13030661
    • ISSN: 1996-1944
    • PMID: 32024274
    • Contributors: Magdalena Obieziurska, Agata J. Pacuła, Anna Laskowska, Angelika Długosz-Pokorska, Anna Janecka, Jacek Ścianowski

 

  • “Molecular Mechanisms of Apoptosis Induced by a Novel Synthetic Quinolinone Derivative in HL-60 Human Leukemia Cells”
    • Journal: Chemico-Biological Interactions
    • Date: April 2020
    • DOI: 10.1016/j.cbi.2020.109005
    • ISSN: 0009-2797
    • Contributors: Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Agata Jaskulska, Tomasz Janecki, Anna Janecka

 

  • “Anticancer Activity of New Ī±-Methylene-Ī“-Lactone DL-247 in Selected Cancer Cell Lines”
    • Type: Conference Paper
    • Date: 2019
    • ISBN: 978-80-907442-0-2
    • Contributors: Katarzyna Gach-Janczak, Angelika Długosz-Pokorska, Joanna Drogosz, R. Jakubowski, Jacek Szymański, Tomasz Janecki, Anna Janecka

 

 

 

Sohrab Behnia | Biophysics | Best Researcher Award

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Ā Prof. Sohrab Behnia | Biophysics |Best Researcher Award

Ā ProfĀ  at Urmia University of Technology, Iran

A seasoned educator and researcher with extensive experience in physics, holding positions from Assistant to Associate Professor at IAU, Urmia, and Urmia University of Technology. Specialized in teaching a range of undergraduate to Ph.D. courses including Quantum Mechanics, Laser Physics, and Nonlinear Dynamical Systems. Proficient in Maple and Matlab programming with a strong background in finite element method analysis. Led impactful research projects in chaotic systems, cancer treatment, and national security, earning multiple awards including the Kharazmi Scientific Festival Second Prize. A recognized leader in academia with a commitment to advancing scientific knowledge and education.

Profile

  1. Scopus

 

  1. Orcid

 

  1. Scholar

šŸŽ“ Professional Teaching Experience (1995-2020):

šŸ§‘ā€šŸ« B.Sc. Courses: General Physics (I & II), Mathematical Physics II, Quantum Mechanics (I & II), Laser, Computational Physics, Wave Physics. šŸŽ“ M.Sc. Courses: Advanced Quantum Mechanics (I & II), Advanced Statistical Mechanics, Electrodynamics I, Advanced Computational Physics. šŸŽ“ Ph.D. Courses: Nonlinear Dynamical and Chaos, Quantum Chaos, Bose Mesner Algebra, Open Quantum Systems. šŸ’» Professional Skills: Maple & Matlab Programming, Finite Element Method Analysis

šŸ¢ Employment:

Assistant Professor: IAU, Urmia (2001-2008), Research Vice-Chancellor of the University (IAU) (2003-2010), Associate Professor: IAU, Urmia (2008-2010), Assistant Professor: Urmia University of Technology (2010-2014), Student Affairs Vice Chancellor of the University (2010-2013), Director of Physics Department (2014-2020)

šŸ”¬ Research Projects:

Solvable Chaotic Maps with Random Dynamical Parameters (1998-2001) – Institute for Research in Fundamental Science (IPM), Iran, Cancer Cells Healing by Using Concentrated Ultrasound Waves (2001-2004) – Sahand University of Technology, Tabriz, Iran, Reconstruction of Phase Space for a Nonlinear Dynamical System by Time Series (2004-2006) – IAU, Urmia, Iran, Designing the System of Confidentiality and Protecting National Security in the Country (2020-2022) – INSF, Iran

šŸ† Awards and Recognitions:

Winning the Second Prize for Conducting the Fundamental Research Project from Kharazmi Scientific Festival, Tehran, Iran (2001), Winning the First Prize for a Research Project from Scientific Festival Urmia, West Azerbaijan (2005), Winning the First Prize for a Research Project from First Basij Festival, Urmia, West Azerbaijan (2006), Ā Winning the First Prize for a Research Project from Scientific Festival Urmia, West Azerbaijan (2008), Ā Winning the Prize of Basij Festival, Tehran, Iran (2010), Winning the First Prize for a Research Project from Scientific Festival Urmia, West Azerbaijan (2022)

Publications Top Notes šŸ“

  • A Novel Algorithm for Image Encryption Based on Mixture of Chaotic Maps
    • Authors: S Behnia, A Akhshani, H Mahmodi, A Akhavan
    • Journal: Chaos, Solitons & Fractals
    • Year: 2008
    • Volume: 35
    • Issue: 2
    • Pages: 408-419
    • Citations: 552

 

  • A Fast Chaotic Encryption Scheme Based on Piecewise Nonlinear Chaotic Maps
    • Authors: S Behnia, A Akhshani, S Ahadpour, H Mahmodi, A Akhavan
    • Journal: Physics Letters A
    • Year: 2007
    • Volume: 366
    • Issues: 4-5
    • Pages: 391-396
    • Citations: 299

 

  • A Novel Scheme for Image Encryption Based on 2D Piecewise Chaotic Maps
    • Authors: A Akhshani, S Behnia, A Akhavan, HA Hassan, Z Hassan
    • Journal: Optics Communications
    • Year: 2010
    • Volume: 283
    • Issue: 17
    • Pages: 3259-3266
    • Citations: 166

 

  • Hierarchy of Chaotic Maps with an Invariant Measure
    • Authors: MA Jafarizadeh, S Behnia, S Khorram, H Nagshara
    • Journal: Journal of Statistical Physics
    • Year: 2001
    • Volume: 104
    • Pages: 1013-1028
    • Citations: 65

 

  • Nonlinear Transitions of a Spherical Cavitation Bubble
    • Authors: S Behnia, A Jafari, W Soltanpoor, O Jahanbakhsh
    • Journal: Chaos, Solitons & Fractals
    • Year: 2009
    • Volume: 41
    • Issue: 2
    • Pages: 818-828
    • Citations: 64

 

  • Suppressing Chaotic Oscillations of a Spherical Cavitation Bubble through Applying a Periodic Perturbation
    • Authors: S Behnia, AJ Sojahrood, W Soltanpoor, O Jahanbakhsh
    • Journal: Ultrasonics Sonochemistry
    • Year: 2009
    • Volume: 16
    • Issue: 4
    • Pages: 502-511
    • Citations: 60

 

  • Multiple-Watermarking Scheme Based on Improved Chaotic Maps
    • Authors: S Behnia, M Teshnehlab, P Ayubi
    • Journal: Communications in Nonlinear Science and Numerical Simulation
    • Year: 2010
    • Volume: 15
    • Issue: 9
    • Pages: 2469-2478
    • Citations: 54

 

  • Image Encryption Based on the Jacobian Elliptic Maps
    • Authors: S Behnia, A Akhavan, A Akhshani, A Samsudin
    • Journal: Journal of Systems and Software
    • Year: 2013
    • Volume: 86
    • Issue: 9
    • Pages: 2429-2438
    • Citations: 53

 

  • DNA Spintronics: Charge and Spin Dynamics in DNA Wires
    • Authors: S Behnia, S Fathizadeh, A Akhshani
    • Journal: The Journal of Physical Chemistry C
    • Year: 2016
    • Volume: 120
    • Issue: 5
    • Pages: 2973-2983
    • Citations: 51

 

Dana Laor | Molecular Biology, | Best Researcher Award

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Dr. Dana Laor | Molecular Biology| Best Researcher Award

šŸ‘Øā€šŸ«Profile Summary

Dr. Dana Laor Bar-Yosef is a distinguished molecular biologist renowned for her groundbreaking research in metabolic disorders. She completed her undergraduate studies in biology at the Hebrew University of Jerusalem, followed by M.Sc. and Ph.D. training at Tel Aviv University under Prof. Martin Kupiec. Her Ph.D. research elucidated the roles of TOR protein kinase in cell signaling and amino acid homeostasis using yeast models. Joining Prof. Ehud Gazit’s lab in 2015, she established innovative in vivo models for studying inborn errors of metabolism (IEMs), leading to significant insights and potential therapeutics. Dr. Laor Bar-Yosef’s expertise spans over 15 years, guiding her leadership of the metabolic research group and pioneering the concept of “Metabolostasis.” Her contributions have been recognized with prestigious awards, including the 2020 Ziegler Award, affirming her exceptional impact on medical research in metabolic disorders.

šŸŒ Professional Profiles

EducationšŸŽ“

Postdoctoral Researcher in Molecular Biology and Nanotechnology Tel Aviv University, Tel Aviv 2015-2018, Ph.D. in Molecular Biology
Tel Aviv University, Tel Aviv 2009-2014 Thesis title: “The role of TOR in rapamycin response in the fission yeast” Advisors: Prof. Martin Kupiec and Prof. Ronit Weisman. M.Sc. in Genetics Tel Aviv University, Tel Aviv 2007-2009 Thesis title: “The TOR pathway regulates cellular growth, gene silencing and telomere length maintenance in the fission yeast” Advisors: Prof. Martin Kupiec and Prof. Ronit Weisman. B.Sc. in Biology
The Hebrew University, Jerusalem 2003-2006

šŸ”¬ Researcher Experience

Head of the Metabolic Research Group Shmunis School of Biomedicine and Cancer Research, Tel Aviv University 2018-Present, Postdoctoral Research School of Molecular Cell Biology and Biotechnology, Tel Aviv University 2015-2018, Graduate Research Department of Microbiology and Biotechnology, Tel Aviv University 2007-2014

Ā Professional DevelopmentĀ  šŸ“ˆ

Women Executive Launchpad in HealthTech 8400 Health Network 2022-2023, Health Care Technological Innovation – From Idea to Commercialization Coller School of Management at Tel-Aviv University and Lahav Executive Education 2022

Ā Teaching ExperiencešŸ“š

Instructor, Introduction to Biology Course Tel Aviv University 2023-2024,Ā  Instructor, “Commercializing University Research” Course
Coller School of Management, Tel Aviv University 2020, Instructor, “Graduate Record Examination Preparation Course”
Tel Aviv University 2014-2015, Teaching Assistant, “Introduction to Genetics” Course Tel Aviv University 2007-2013

Awards šŸ†

The Late Breaking News Awards at the 2023 SSIEM Symposium 2023, The Ziegler Award for Research in the Field of Metabolic Disorders
2020, The Herbert and Sharon Glazer Fund Excellence Award 2017 And more…

Funding AcquiredšŸ’°

The John Templeton Foundation Research Grant 2021-2024, Israel Science Foundation Research Grant 2019-2023, Momentum Fund Investment in Promising Breakthrough Technologies 2021-2023 And more…

Ā PatentsšŸ› ļø

Laor, D., & Gazit, E (2018). Integrated drug discovery platform for inborn error of metabolism disorders.
US Provisional Patent Application No. 62/779,054. Pending. Laor, D., Sade, D., and Gazit, E (2021). Integrated drug discovery platform for protein misfolding disorders associated with metabolite accumulation.
Provisional.

Ā Conference and Scientific MeetingsšŸŒ

The first Metabolostasis conference, Israel (2023) Organizing Committee, ILASOL 36th Annual Meeting, Israel (2023)
Organizing Committee and Chair, Rare Connections 2022, Israel A conference dedicated for potential collaborations in the field of rare diseases. ISM 2022 Annual Meeting, Israel The first Israel Metabolomics Meeting, Israel (2022) And more…

Ā Community InvolvementšŸ‘„

Instructor, Jewish Community Center (JCC), Ohio, USA (2002, 2003) Guided Jewish-American youth about the Israeli Culture in a youth summer camp. Armor Instructor, Israel Defense Forces (2000-2002) Served as an armor guide for regular service and reserve duty soldiers at the Armored Corps School. Counselor, ā€œMaccabi Tzairā€ Youth Movement, Israel (1996-2000) Served as a counselor and teaching coordinator, mentoring and advocating Israeli youth.

šŸ“šTop Noted Publication

  1. TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions
    • Authors: M Schonbrun, D Laor, L LĆ³pez-Maury, J BaĢˆhler, M Kupiec, R Weisman
    • Journal: Molecular and cellular biology
    • Volume: 29
    • Issue: 16
    • Pages: 4584-4594
    • Citations: 72
    • Year: 2009

 

  1. Two Decades of Studying Functional Amyloids in Microorganisms
    • Authors: SA Levkovich, E Gazit, D Laor Bar-Yosef
    • Journal: Trends in Microbiology
    • Citations: 68
    • Year: 2021

 

  1. Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation
    • Authors: D Laor, D Sade, S Shaham-Niv, D Zaguri, M Gartner, V Basavalingappa, …
    • Journal: Nature communications
    • Volume: 10
    • Issue: 1
    • Pages: 62
    • Citations: 54
    • Year: 2019

 

  1. Yeast models for the study of amyloid-associated disorders and development of future therapy
    • Authors: S Rencus-Lazar, Y DeRowe, H Adsi, E Gazit, D Laor
    • Journal: Frontiers in Molecular Biosciences
    • Volume: 6
    • Pages: 15
    • Citations: 45
    • Year: 2019

 

  1. TORC1 regulates developmental responses to nitrogen stress via regulation of the GATA transcription factor Gaf1
    • Authors: D Laor, A Cohen, M Kupiec, R Weisman
    • Journal: MBio
    • Volume: 6
    • Issue: 4
    • Citations: 33
    • Year: 2015
  1. Engineered riboswitch nanocarriers as a possible disease-modifying treatment for metabolic disorders
    • Authors: S Zilberzwige-Tal, D Gazit, H Adsi, M Gartner, R Behl, D Bar-Yosef Laor, …
    • Journal: ACS nano
    • Volume: 16
    • Issue: 8
    • Pages: 11733-11741
    • Citations: 3
    • Year: 2022

 

  1. Integrated drug discovery platform for inborn error of metabolism disorders
    • Authors: E Gazit, L Dana
    • Patent: US Patent App. 17/345,248
    • Citations: 1
    • Year: 2021

 

  1. Mind your marker: the effect of common auxotrophic markers on complex traits in yeast
    • Authors: K Kaplan, SA Levkovich, Y DeRowe, E Gazit, D Laor Barā€Yosef
    • Journal: The FEBS Journal
    • Year: 2024

 

  1. The von Hippel-Lindau protein forms fibrillar amyloid assemblies that are mitigated by the anti-amyloid molecule Purpurin
    • Authors: V Kumar, V Kaushik, S Kumar, SA Levkovich, P Gupta, DL Bar-Yosef, …
    • Journal: Biochemical and Biophysical Research Communications
    • Volume: 690
    • Pages: 149250
    • Year: 2024

 

  1. Branched-Chain Amino Acid Assembly into Amyloid-like Fibrils Provides a New Paradigm for Maple Syrup Urine Disease Pathology
    • Authors: T Kreiser, I Sogolovsky-Bard, D Zaguri, S Shaham-Niv, D Laor Bar-Yosef, …
    • Journal: International Journal of Molecular Sciences
    • Volume: 24
    • Issue: 21
    • Pages: 15999
    • Year: 2023