Julien Olivet | Epigenetics | Young Scientist Award

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Dr.Julien Olivet | Epigenetics | Young Scientist Award

Dr Julien Olivet Rega Institute/KU Leuven Belgium

Julien Olivet is an exceptional candidate for the Young Scientist Award due to his innovative research in structural and chemical biology, leadership in managing research projects, and significant international recognition. His technical expertise, particularly in cryo-EM and drug discovery, stands out. Additionally, his commitment to teaching and science outreach is commendable. To strengthen his candidacy, he could emphasize the real-world impact of his research and diversify his research topics and publications. Overall, Julienā€™s achievements and contributions make him a highly deserving nominee for the award.

Publication profile

scholar

šŸŽ“ Education

PhD in Biochemistry, Molecular and Cellular Biology, Bioinformatics and ModelingUniversitĆ© de LiĆØge, Belgium (2015-2021)Thesis: Selective disruption of histone deacetylase complexes by small-molecule inhibitors.MSc in Chemistry of Life and NanomaterialsUniversitĆ© de Namur, Belgium (2013-2015)Thesis: Synthesis of alginate/SiO2-TiO2 hybrid material for cell encapsulation.BSc in ChemistryFacultĆ©s Universitaires Notre-Dame de la Paix, Namur, Belgium (2009-2013).High School Diploma in Mathematics, Sciences Institut Notre-Dame de Loverval, Belgium (2003-2009).

šŸ”¬ Research Experience

Postdoctoral Fellow, KU Leuven (09/2021-present),Focus: Cryo-EM structures of SIN3 histone deacetylase (HDAC) complexes, managing collaborations, drug design.Visiting Senior Scientist, UniversitĆ© de LiĆØge (09/2021-present)Focus: Inhibitors of SIN3 protein in HDAC complexes, drug screening, spin-off development.PhD Research Fellow, UniversitĆ© de LiĆØge (01/2021-06/2021)Focus: Small molecule screening pipelines, virus-host interactions.Visiting FRS-FNRS/WBI PhD Research Fellow, Harvard Medical School (11/2015-12/2020)
Focus: Chemical genetic selections, protein interaction assays.

šŸ† Honours and Awards

NSFC-FWO Collaboration Project Award (2024-2025),Research Foundation Flanders (FWO), Belgium.McKinsey & Company Scientific Award (2022)EUR 5000.Marie Skłodowska-Curie Actions (MSCA) European Postdoctoral Fellowship (2022-2024),EUR 191760.Best Oral Presentation Award (2019)Dana-Farber Cancer Institute, USA.

Publication

  • Maximizing binary interactome mapping with a minimal number of assays
    • Authors: SG Choi, J Olivet, P Cassonnet, PO Vidalain, K Luck, L Lambourne, …
    • Year: 2019
  • The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
    • Authors: C Vandermeulen, T Oā€™Grady, J Wayet, B Galvan, S Maseko, M Cherkaoui, …
    • Year: 2021
  • Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells
    • Authors: D Kerselidou, BS Dohai, DR Nelson, S Daakour, N De Cock, …
    • Year: 2021
  • A systematic approach to identify host targets and rapidly deliver broad-spectrum antivirals
    • Authors: J Olivet, SB Maseko, AN Volkov, K Salehi-Ashtiani, K Das, …
    • Year: 2022
  • AI-guided pipeline for proteinā€“protein interaction drug discovery identifies a SARS-CoV-2 inhibitor
    • Authors: P Trepte, C Secker, J Olivet, J Blavier, S Kostova, SB Maseko, I Minia, …
    • Year: 2024
  • Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
    • Authors: SB Maseko, Y Brammerloo, I Van Molle, A Sogues, C Martin, C Gorgulla, …
    • Year: 2023
  • A quantitative mapping approach to identify direct interactions within complexomes
    • Authors: P Trepte, C Secker, SG Choi, J Olivet, ES Ramos, P Cassonnet, S Golusik, …
    • Year: 2021
  • Expanding the HDAC druggable landscape beyond enzymatic activity
    • Authors: J Olivet, SG Choi, S Sierra, TM O’Grady, M de la Fuente Revenga, F Laval, …
    • Year: 2023
  • Interactome and structural basis for targeting the human T-cell leukemia virus Tax oncoprotein
    • Authors: SB Maseko, I Van Molle, K Blibek, C Gorgulla, J Olivet, J Blavier, …
    • Year: 2021
  • The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
    • Authors: C Vandermeulen, T Oā€™Grady, B Galvan, M Cherkaoui, A Desbuleux, …
    • Year: 2021
  • Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule
    • Authors: SB Maseko, I Van Molle, K Blibek, C Gorgulla, J Olivet, J Blavier, …
    • Year: 2021
  • Selective disruption of histone deacetylase complexes by small-molecule inhibitors of protein interactions
    • Author: J Olivet
    • Year: 2021

 

šŸ… Conclusion

Julien Olivet is a strong candidate for the Young Scientist Award due to his outstanding research achievements, leadership skills, and contributions to the scientific community. His innovative work in cryo-EM and drug discovery, combined with his active role in mentoring and outreach, aligns well with the criteria for the award. Addressing the areas for improvement, particularly in demonstrating the broader impact of his research and expanding his publication portfolio, could further solidify his candidacy.

Thi Mong Diep Nguyen | Molecular Biology | Best Researcher Award

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Assoc Prof Dr. Omvir Singh| Molecular Biology | Best Researcher Award

šŸ”¬šŸ§¬ Holding a Doctor of Science in Life Science (Cell Biotechnology) from the University of Tours, France, I’ve delved into diverse realms including cell biology, microbiology, and animal reproduction. As a Visiting Professor at the University of FranƧois-Rabelais and an Associate Professor at Quy Nhon University, I’ve led research projects exploring avian reproductive biotechnologies and the impact of AMPK protein kinase on male gonad functions. My contributions to grants investigating hCG glycoforms and fertility treatments showcase my dedication to advancing scientific understanding. šŸŒ±šŸ‘Øā€šŸ”¬

Profile

Scopus

Orcid

Scholar

Training Background:

University of Tours, France Years: 4/2022 Major/ Specialty: Life Science (Cell biotechnology) Academic Degree: Doctor of Science University of FranƧois-Rabelais, Tours, France Years: 1/2020 – 3/2020 Major/ Specialty: Biotechnology Role: Visiting Professor Quy Nhon University Year: 1/2020 Major/ Specialty: Biotechnology Role: Associate Professor INRA _Institut national de la recherche agronomique (Nouzilly), France Years: 10/2018 – 2/2019, 11/2016 – 04/2017 Major/ Specialty: Animal Cell Biotechnology + Immunology + Gonadotropins Role: Postdoctoral Researcher FranƧois-Rabelais University, France Years: 11/2011 – 10/2015 Major/ Specialty: Life Science (Cell biotechnology) Academic Degree: Ph.D Quy Nhon University Years: 9/2005 – 6/2008 Major/ Specialty: Biology Academic Degree: Master Quy Nhon University Years: 9/2001 – 9/2005 Major/ Specialty: Biology Academic Degree: Bachelor

 

šŸ”Research Projects (Last 5 Years):

CRYOBIRD – Development of avian reproductive biotechnologies for the management of genetic diversity Years: 10/2010 – 10/2014 Funding Institution: France Role: Participant. Study on pathogenic microorganisms in Arachis Hypogaea L. in ecological condition of Hoai An district, Binh Dinh province Year: 2016 – 2017 Funding Institution: Quy Nhon University Role: Chairman Impact of AMPK protein kinase on male gonad and spermatozoa functions Years: 2018 – 2019 Funding Institution: Quy Nhon University Role: Chairman Characterization of new hCG glycoforms for implantation and early pregnancy diagnostic Years: 2017 – 2020 Funding Institution: France Role: Participant Investigation on the role of 5ā€™-AMP activated protein kinase (AMPK) in adenylate cyclase gene expression using pharmacologicals activators and human Luteinizing Hormone (hLH) or Forskolin stimulators in Leydig MLTC-1 cells Years: 2018 – 2020 Funding Institution: NAFOSTED Role: Chairman Production of single-chain gonadotropins for fertility treatments Years: 2020 – 2023 Funding Institution: VINIF Role: Chairman

Publications Top Notes šŸ“

  1. Highly-Sensitive In Vitro Bioassays for FSH, TSH, PTH, Kp, and OT in Addition to LH in Mouse Leydig Tumor Cell
    • Authors: Klett, D., Pellissier, L., Lomet, D., Jean-Alphonse, F., Combarnous, Y.
    • Year: 2023

 

  1. Undissociable chemically cross-linked and single-chain gonadotropins
    • Authors: Nguyen, T.M.D., Klett, D., Combarnous, Y.
    • Year: 2023

 

  1. Impact of microwave synthesis time on the shape of silver nanostructures and their antibacterial activity
    • Authors: Hoang, N.H., Nguyen, V.N., Nguyen, T.T., Nguyen, T.M.D.
    • Year: 2023

 

  1. Natural and recombinant equine chorionic gonadotropins past and future in animal reproductive technology
    • Authors: Thach, D.T., Cuong, B.K., Van Tong, H., Combarnous, Y., Nguyen, T.M.D.
    • Year: 2022

 

  1. Effect of fluoxetine on cyclic adenosine monophosphate response to follicle-stimulating hormone in HEK cells
    • Authors: Nguyen, T.T., Nguyen, T.M.D.
    • Year: 2022

 

  1. Membrane Hormone Receptors and Their Signaling Pathways as Targets for Endocrine Disruptors
    • Authors: Combarnous, Y., Nguyen, T.M.D.
    • Year: 2022

 

  1. Roles of Soluble Adenylyl Cyclase in cAMP Synthesis in Animal Cells
    • Author: Nguyen, T.M.D.
    • Year: 2022

 

Hyun Suk Shin | Molecular Biology | Best Researcher Award

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Ā Dr. Hyun Suk Shin | Molecular Biology | Best Researcher Award

Ā Dr. University of Las Palmas de Gran Canaria,Ā  Spain

šŸ‘©ā€šŸ”¬ Hyun Suk Shin is a Marine Biotechnology expert with a rich academic background. She holds a B.Sc., M.Sc., and Ph.D. from Korea Maritime and Ocean University, where she delved into various aspects of aquaculture, molecular biology, and biochemistry. With extensive research experience, including international collaborations, she has contributed significantly to the field, resulting in numerous publications and patents. As a postdoctoral researcher, she continued her impactful work at institutions like the National Fisheries Research and Development Institute of Korea and the FundaciĆ³n Canaria Parque CientĆ­fico TecnolĆ³gico de la Universidad de Las Palmas de Gran Canaria. Recognized for her excellence, she received prestigious scholarships and awards, demonstrating her dedication to advancing aquaculture research.

 

Profile

Scopus

Scholar

Education šŸ“š

  1. Higher Degree
    • Name of Qualification: M.S. Science
    • Degree Awarding Entity: Korea Maritime and Ocean University
    • Date of Qualification: 28/02/2010
  2. Higher Degree
    • Name of Qualification: B.S. Science, Marine Biotechnology
    • Degree Awarding Entity: Korea Maritime and Ocean University
    • Date of Qualification: 28/02/2008

Doctorates

  • PhD Science
    • Degree Awarding Entity: Korea Maritime and Ocean University
    • Date of Degree: 28/02/2014

Teaching ExperiencešŸ“Š

Experience Supervising Doctoral Theses and/or Final Year Projects: Project Title: Analysis of Skeletal Deformities in Gilthead Sea Bream Entity: Universidad de las Palmas de Gran Canaria Type of Entity: University Student: Alvaro Lorenzo Felipe Date of Reading: 05/07/2022Project Title: Programa Mejora GenĆ©tica en CamarĆ³n Entity: Universidad de las Palmas de Gran Canaria Type of Entity: University

 

Scientific or Technological Activities šŸ”¬

R&D Projects Funded Through Competitive Calls of Public or Private Entities

  1. Project Name: AquaIMPACT: Genomic and Nutritional Innovation for Genetically Superior Farmed Fish

Keywords: Molecular markers and recognition; Genetics transcription; Genetics expression of regulations; Epigenetics; Genetic drift; Population geneticsType of Project: Research and development, including transferGeographical Area: European UnionDegree of Contribution: ResearcherEntity: Universidad de las Palmas de Gran CanariaType of Entity: UniversityCity of Entity: Las Palmas de Gran Canaria, Canary Islands, SpainPrincipal Investigators: Daniel Montero VĆ­torres; Marisol Izquierdo Lopez; Juan Manuel Afonso Lopez; Maria Jesus Zamorano Serrano; Silvia Torrecillas Burriel; Hyun Suk Shin; Cathaysa PĆ©rez GarcĆ­aNumber of Researchers: 72Number of People/Year: 14Type of Participation: Team memberProgramme Name: Horizon 2020 Research and InnovationCode: 818367Start-End Date: 01/01/2018 – 02/01/2023Duration: 5 yearsParticipating Entities: [List of entities involved]Total Amount: ā‚¬6,100,000Sub-Project Amount: ā‚¬702,913Percentage as Grant: 100%Relevant Results: Determining the additive genetic components of immune system traits of sea bream and sea bass populations under genetic selection pressure for growth.Dedication Regime: Part-timeApplicant’s Contribution: In this project, my contribution is assigned within the WP2: Nutritional Innovation: Precision nutrition for superior genotypes, through the following tasks:Evaluation and divergent selection of sea bream breeders for growth and absence of skeletal deformities.Breeding, marking, fattening, and characterization of offspring and breeders using microsatellite markers “SMsa-1/ SMsa-2”.Study of genetic parameters of immune system traits.

Project Name: PerformFISH – Consumer Driven Production: Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chain

Keywords: Genetics expression of regulations; Genetic drift; Population geneticsType of Project: Research and development, including transferGeographical Area: European Union[Include any additional information about the project here]

Publications Top Notes šŸ“

  • Effects of LED light spectra on oxidative stress and the protective role of melatonin in relation to the daily rhythm of the yellowtail clownfish, Amphiprion clarkii
    • Authors: HS Shin, J Lee, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Year: 2011

 

  • Effect of LED light spectra on starvation-induced oxidative stress in the cinnamon clownfish Amphiprion melanopus
    • Authors: CY Choi, HS Shin, YJ Choi, NN Kim, J Lee, GS Kil
    • Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Year: 2012

 

  • Kisspeptin regulates the hypothalamusā€“pituitaryā€“gonad axis gene expression during sexual maturation in the cinnamon clownfish, Amphiprion melanopus
    • Authors: NN Kim, HS Shin, YJ Choi, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
    • Year: 2014

 

  • Effects of LED light spectra on the growth of the yellowtail clownfish Amphiprion clarkii
    • Authors: HS Shin, J Lee, CY Choi
    • Journal: Fisheries Science
    • Year: 2012

 

  • Profiles of antioxidant gene expression and physiological changes by thermal and hypoosmotic stresses in black porgy (Acanthopagrus schlegeli)
    • Authors: KW An, NN Kim, HS Shin, GS Kil, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Year: 2010

 

  • The effects of quercetin on physiological characteristics and oxidative stress resistance in olive flounder, Paralichthys olivaceus
    • Authors: HS Shin, JH Yoo, TS Min, KY Lee, CY Choi
    • Journal: Asian-Australasian Journal of Animal Sciences
    • Year: 2010

 

  • Selection for growth is associated in gilthead sea bream (Sparus aurata) with diet flexibility, changes in growth patterns and higher intestine plasticity
    • Authors: E Perera, P SimĆ³-Mirabet, HS Shin, E Rosell-Moll, F Naya-CatalĆ”, …
    • Journal: Aquaculture
    • Year: 2019

 

  • Quantitative mRNA expression of sox3 and DMRT1 during sex reversal, and expression profiles after GnRHa administration in black porgy, Acanthopagrus schlegeli
    • Authors: HS Shin, KW An, MS Park, MH Jeong, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
    • Year: 2009