Afif Ben Mahmoud | Genomics | Excellence in Research

Ā Dr. Afif Ben Mahmoud | Genomics | Excellence in Research Ā 

Ā Dr at Qatar Biomedical Research Institute,Ā  Qatar

Afif Ben Mahmoud, Ph.D., is a Senior Research Associate at the Neurological Disorders Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, in Doha, Qatar. A Tunisian national, Dr. Ben Mahmoud specializes in human molecular genetics and has dedicated over ten years to researching neurological disorders and genetic diseases. He holds a Ph.D. in Biological Sciences and has made significant contributions to understanding neurodevelopmental disorders through innovative research techniques and mentoring graduate students. His work emphasizes the identification of genetic factors in various disorders, making him a vital asset to the scientific community in Qatar and beyond.

Profile

Scopus

Scholar

Education šŸŽ“

Dr. Ben Mahmoud earned his Ph.D. in Biological Sciences (Human Molecular Genetics) from the Faculty of Sciences of Sfax, University of Sfax, Tunisia, in 2015. Prior to this, he obtained a Masterā€™s degree in Genetics and Biodiversity from the Higher Institute of Biotechnology of Monastir, Tunisia, in 2009. His academic journey began with an Engineering degree in Animal Production from the Higher School of Agronomy of Mateur, University of Carthage, Tunisia, in 2007. This solid educational foundation has equipped him with the necessary skills and knowledge to excel in his research endeavors.

Experience šŸ’¼

Since 2019, Dr. Ben Mahmoud has served as a Senior Research Associate at the Qatar Biomedical Research Institute, where he identifies and characterizes candidate genes for neurodevelopmental disorders by analyzing whole exome and whole genome sequencing data. Before this, he was a Postdoctoral Researcher at the College of Medicine and Health Sciences, University of UAE, from 2016 to 2018, focusing on genomic and cellular studies of autosomal recessive disorders. He has also taught cell biology and genetics at various higher education institutions in Tunisia, contributing to the academic development of future scientists.

Awards and Honors šŸ†

Dr. Ben Mahmoud has received recognition for his contributions to genetic research and education. He participated in the development of cell lines using CRISPR-Cas9 technology at UAEU, which aims to better understand diseases. His work has been featured in multiple peer-reviewed publications, establishing him as an authority in his field. He has been actively involved in mentoring students, fostering the next generation of researchers, and enhancing the academic environment in which he works.

Research Focus šŸ”¬

Dr. Ben Mahmoud’s research primarily focuses on neurological disorders and human genetic diseases, specifically identifying the genetic basis of neurodevelopmental disorders. He employs advanced techniques such as next-generation sequencing and molecular biology methods to analyze candidate genes. His recent studies aim to elucidate the cellular mechanisms behind disease-causing mutations, contributing to the broader understanding of genetic disorders. Dr. Ben Mahmoud’s work is instrumental in developing targeted therapeutic strategies, enhancing the potential for personalized medicine in treating complex genetic conditions.

Conclusion šŸ“

Dr. Afif Ben Mahmoud exemplifies excellence in research through his substantial contributions to the field of neurological disorders and human genetics. His extensive experience, technical expertise, and commitment to mentorship position him as a strong candidate for the Excellence in Research Award. By addressing potential areas for improvement, such as broadening his research focus and enhancing public engagement, Dr. Ben Mahmoud could further amplify his impact within the scientific community and beyond. His ongoing work promises to advance our understanding of complex genetic diseases, making him a valuable asset to the field.

Publications Top Notes

  • Antagonist effects of Bacillus spp. strains against Fusarium graminearum for protection of durum wheat (Triticum turgidum L. subsp. durum)
    • Authors: I Zalila-Kolsi, AB Mahmoud, H Ali, S Sellami, Z Nasfi, S Tounsi, …
    • Journal: Microbiological Research, 2016
    • Pages: 148-158

 

  • Mitochondrial DNA mutations and polymorphisms in asthenospermic infertile men
    • Authors: S Baklouti-Gargouri, M Ghorbel, A Ben Mahmoud, E Mkaouar-Rebai, …
    • Journal: Molecular Biology Reports, 2013
    • Volume/Pages: 40, 4705-4712

 

  • A novel mutation MT-COIII m.9267G>C and MT-COI m.5913G>A mutation in mitochondrial genes in a Tunisian family with maternally inherited diabetes and deafness (MIDD)
    • Authors: M Tabebi, E Mkaouar-Rebai, M Mnif, F Kallabi, AB Mahmoud, WB Saad, …
    • Journal: Biochemical and Biophysical Research Communications, 2015
    • Volume/Pages: 459(3), 353-360

 

  • Genetics of hypogonadotropic hypogonadismā€”Human and mouse genes, inheritance, oligogenicity, and genetic counseling
    • Authors: ED Louden, A Poch, HG Kim, A Ben-Mahmoud, SH Kim, LC Layman
    • Journal: Molecular and Cellular Endocrinology, 2021
    • Volume: 534, 111334

 

  • Identification of a novel m.9588G>A missense mutation in the mitochondrial COIII gene in asthenozoospermic Tunisian infertile men
    • Authors: S Baklouti-Gargouri, M Ghorbel, A Ben Mahmoud, E Mkaouar-Rebai, …
    • Journal: Journal of Assisted Reproduction and Genetics, 2014
    • Volume/Pages: 31, 595-600

 

  • A novel aberrant splice site mutation in COL27A1 is responsible for Steel syndrome and extension of the phenotype to include hearing loss
    • Authors: N Gariballa, A Ben-Mahoud, M Komara, AM Al-Shamsi, …
    • Journal: American Journal of Medical Genetics Part A, 2017
    • Volume/Pages: 173(5), 1257-1263

 

  • Whole mitochondrial genome screening of a family with maternally inherited diabetes and deafness (MIDD) associated with retinopathy: A putative haplotype associated to MIDD and its phenotypic implications
    • Authors: M Tabebi, N Charfi, F Kallabi, O Alila-Fersi, AB Mahmoud, A Tlili, …
    • Journal: Journal of Diabetes and its Complications, 2017
    • Volume/Pages: 31(1), 253-259

 

  • Two novel mutations in COII and tRNAHis mitochondrial genes in asthenozoospermic infertiles men
    • Authors: BG Siwar, G Myriam, BM Afif, MR Emna, C Nozha, S Afifa, F Faiza, …
    • Journal: Biochemical and Biophysical Research Communications, 2014
    • Volume/Pages: 450(1), 610-615

 

  • A novel m.6307A>G mutation in the mitochondrial COXI gene in asthenozoospermic infertile men
    • Authors: S Baklouti-Gargouri, M Ghorbel, A Ben Mahmoud, E Mkaouar-Rebai, …
    • Journal: Molecular Reproduction and Development, 2013
    • Volume/Pages: 80(7), 581-587

 

  • Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applicationsā€”A Comprehensive Review
    • Authors: I Zalila-Kolsi, A Ben-Mahmoud, R Al-Barazie
    • Journal: Microorganisms, 2023
    • Volume/Pages: 11(9), 2215

 

  • Novel cases of Tunisian patients with mutations in the gene encoding 17Ī²-hydroxysteroid dehydrogenase type 3 and a founder effect
    • Authors: BB Rhouma, F Kallabi, N Mahfoudh, AB Mahmoud, RT Engeli, H Kamoun, …
    • Journal: The Journal of Steroid Biochemistry and Molecular Biology, 2017
    • Volume/Pages: 165, 86-94

 

  • Eif2b3 mutants recapitulate phenotypes of vanishing white matter disease and validate novel disease alleles in zebrafish
    • Authors: YR Lee, SH Kim, A Ben-Mahmoud, OH Kim, TI Choi, KH Lee, B Ku, J Eum, …
    • Journal: Human Molecular Genetics, 2021
    • Volume/Pages: 30(5), 331-342

 

Annesha Chakraborty| Bioinformatics | Women Researcher Award

Ā Dr. Annesha Chakraborty | Bioinformatics | Women Researcher Award

Ā Dr. SASTRA DEEMED UNIVERSITY

šŸ‘©ā€šŸ”¬ A highly motivated Ph.D. candidate at SASTRA Deemed University, specializing in Bioinformatics and Biomolecular Crystallography, with hands-on experience in molecular docking, dynamics, and laboratory techniques. Possessing an M.Sc. in Microbiology and B.Sc. (Hons.) in Microbiology, Chemistry, and Botany, I excel in research and academic achievements. As a Research Intern at MEAB LAB and Lab Tech. Intern at Suraksha Diagnostic Pvt. Ltd., I contributed to multiple publications and gained expertise in DNA/RNA extraction and PCR. Currently engaged in molecular dynamics studies on COVID Mpro, biomass production, and A.baumanniiā€™s efflux pump research. Passionate about advancing scientific knowledge and addressing real-world challenges.šŸŒŸ

 

Profile

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šŸŽ“ Education

Doctor of Philosophy (2023-Ongoing) SASTRA Deemed University, India Bioinformatics Center and Biomolecular Crystallography Lab, under the supervision of Dr. S. Thamotharan and co-supervision of Dr. Vigneshwer R. Currently pursuing research funded by DBT-govt. of India. M.Sc in Microbiology (2020-2022) Grade: A+ (80%) [Ranked 4th] B.Sc (Hons.) in Microbiology (2017-2020) Optional subjects: Chemistry and Botany Grade: B+ 12th (High School) (2015-2017) Science stream

šŸ”¬ Key Skills

  • Molecular Docking
  • Molecular Dynamics
  • Schrodinger
  • Pymol
  • MegaAUTODOCK
  • Agarose Gel Electrophoresis
  • ELISA
  • qPCR
  • RT-PCR
  • Flow Cytometry
  • Online tools for nucleic acid or protein sequence-based analysis (Expasy, Clustal Omega, NCBI)

šŸ’¼ Work Experience

Research Intern at MEAB LAB (08/2021-09/2022) JIS University (Hybrid mode) Responsibilities: Worked on current research projects with PhD scholars as a Project Associate Intern. Co-authored 3 review articles and 1 book chapter, and contributed to 3 research projects. Previously worked here for Master’s thesis paper. Lab Tech Intern at Suraksha Diagnostic Pvt. Ltd. (12.08.2022-24.08.2022) Responsibilities: Conducted DNA and RNA extraction for PCR to detect HLA, hepatitis B, hepatitis C, and Covid-19 virus. Performed RT-PCR and real-time PCR to detect RNA and DNA viruses.

Publications Top Notes šŸ“

  1. Title: Lignocellulolytic Microbial Systems and its Importance in Dye Decolourization: A Review

 

  1. Title: Microbial electrolysis cells for effective biohydrogen biogenesis from biowastes

 

  1. Title: Algae educed industrial enzymes production: a sustainable way forward?
    • Book: Industrial Microbiology
    • ISBN: 978-93-5461-997-7
    • Publisher: Astral International Pvt. Ltd. (Scopus)