Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

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Dr. Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

Dr at Medical University of ÅĆ³dÅŗ, Poland

Angelika Długosz-Pokorska, born on January 15, 1990, in ÅĆ³dÅŗ, Poland, is a Research Associate at the Medical University of ÅĆ³dÅŗ, specializing in medicinal chemistry and cancer research. She leads projects on anticancer compounds, opioid analogs, and their pharmacological effects, contributing to multiple EU-funded research initiatives.

Profile

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orcid

Education šŸŽ“

Angelika holds a Ph.D. in Medicinal Chemistry from the Medical University of ÅĆ³dÅŗ, Poland, and has undergone research training at the University of Rouen, France, in neuropsychopharmacology.

Experience šŸ§‘ā€šŸ«

With over 7 years of research experience, Angelika has served as Principal Investigator and Co-investigator for numerous projects, including anticancer activity studies and pharmacological analysis of synthetic peptides and compounds. She has also supervised and mentored young researchers and students.

Awards and Honors šŸ†

Angelika has received multiple accolades, including “Skuteczna Kobieta Roku 2021” (Effective Woman of the Year) in the Science category, Rector’s Awards for outstanding publications, and a First-level Special Award for Didactic Excellence.

Research Focus šŸ”

Angelikaā€™s research focuses on the development of new hybrid anticancer agents, including those with uracil skeletons and methylene groups. Her work also explores the role of endomorphin analogs in neuroprotection and cancer treatment.

Publications šŸ“š

 

  • “Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluationā€”Part I”
    • Journal: Materials
    • Date: February 15, 2024
    • DOI: 10.3390/ma17040899
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides”
    • Journal: Pharmaceuticals
    • Date: November 4, 2023
    • DOI: 10.3390/ph16111560
    • ISSN: 1424-8247
    • Contributors: Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells”
    • Journal: Biologics: Targets and Therapy
    • Date: May 2023
    • DOI: 10.2147/btt.s405080
    • ISSN: 1177-5491
    • Contributors: Angelika Długosz-Pokorska, Renata Perlikowska, Tomasz Janecki, Anna Janecka

 

  • “Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics”
    • Journal: Materials
    • Date: March 11, 2022
    • DOI: 10.3390/ma15062068
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Joanna Pacuła-Miszewska, Angelika Długosz-Pokorska, Anna Janecka, Andrzej Wojtczak, Jacek Scianowski

 

  • “A New Hybrid Ī“-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells”
    • Journal: Molecules
    • Date: 2020
    • DOI: 10.3390/molecules25071479
    • ISSN: 1420-3049
    • Contributors: Katarzyna Gach-Janczak, Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Rafał Jakubowski, Tomasz Janecki, Jacek Szymański, Anna Janecka

 

  • “New Uracil Analog U-332 is an Inhibitor of NF-ĪŗB in 5-Fluorouracil-Resistant Human Leukemia HL-60 Cell Line”
    • Journal: BMC Pharmacology & Toxicology
    • Date: 2020
    • DOI: 10.1186/s40360-020-0397-4
    • ISSN: 1471-2210
    • Contributors: Angelika Długosz-Pokorska, Marlena Pięta, Jacek Kędzia, Tomasz Janecki, Anna Janecka

 

  • “New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents”
    • Journal: Anti-Cancer Agents in Medicinal Chemistry
    • Date: 2020
    • DOI: 10.2174/1871520619666191211104128
    • ISSN: 1871-5206
    • PMID: 31823706
    • Contributors: Angelika Długosz-Pokorska, Joanna Drogosz-Stachowicz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski, Anna Janecka

 

  • “Seleninic Acid Potassium Salts as Water-Soluble Biocatalysts with Enhanced Bioavailability”
    • Journal: Materials
    • Date: 2020
    • DOI: 10.3390/ma13030661
    • ISSN: 1996-1944
    • PMID: 32024274
    • Contributors: Magdalena Obieziurska, Agata J. Pacuła, Anna Laskowska, Angelika Długosz-Pokorska, Anna Janecka, Jacek Ścianowski

 

  • “Molecular Mechanisms of Apoptosis Induced by a Novel Synthetic Quinolinone Derivative in HL-60 Human Leukemia Cells”
    • Journal: Chemico-Biological Interactions
    • Date: April 2020
    • DOI: 10.1016/j.cbi.2020.109005
    • ISSN: 0009-2797
    • Contributors: Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Agata Jaskulska, Tomasz Janecki, Anna Janecka

 

  • “Anticancer Activity of New Ī±-Methylene-Ī“-Lactone DL-247 in Selected Cancer Cell Lines”
    • Type: Conference Paper
    • Date: 2019
    • ISBN: 978-80-907442-0-2
    • Contributors: Katarzyna Gach-Janczak, Angelika Długosz-Pokorska, Joanna Drogosz, R. Jakubowski, Jacek Szymański, Tomasz Janecki, Anna Janecka

 

 

 

Sayoni Maitra Roy | Biochemistry | Women Researcher Award

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Dr. Sayoni Maitra Roy | Biochemistry | Women Researcher Award

Ā Dr at Guru Nanak University,Ā  India

Sayoni Maitra Roy is an Assistant Professor in the Department of Biotechnology at Guru Nanak University, Hyderabad. With a PhD in Biotechnology, she specializes in precision therapy research, focusing on innovative drug delivery systems and targeted therapies. Sayoni is passionate about translating scientific discoveries into practical applications, enhancing patient outcomes, and mentoring future scientists. Her interdisciplinary approach blends biology, chemistry, nanotechnology, and medicine, driving impactful research initiatives that address complex healthcare challenges.

Profile

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Scholar

Education šŸŽ“

Sayoni completed her PhD in Biotechnology at Amity University Kolkata (2020-2024), where she researched ligand-installed nanomedicine for biomedical applications under Dr. Amit Ranjan Maity. She earned her M.Sc. in Zoology from Durgapur Government College (2017-2019), graduating as the batch topper, and a B.Sc. in Zoology from Rammohan College, Calcutta University (2007-2010). Additionally, she was a top achiever in Retail & Sales Management at ITM University, Raipur (2011-2012).

Experience šŸ’¼

Sayoni has served as an Assistant Professor at Guru Nanak University, where she guides PhD students and teaches undergraduate courses. Prior to this, she was a research student at Amity Institute of Biotechnology for four years. Sayoni has eight years of experience as a NEET educator, specializing in Biology and Zoology, and worked as a Senior Associate at Wipro Ltd. Her diverse background combines teaching, research, and industry experience, enhancing her educational impact.

Awards and Honors šŸ†

Sayoni has received numerous accolades, including the Best Poster Presentation Award from Bhabha Atomic Research Centre for her work on nanomedicine. She was recognized for her academic excellence in the Retail Banking and Sales Management program at ITM University. Additionally, she has been awarded certificates of recognition from the American Chemical Society and the Board of Research in Nuclear Sciences for her contributions to cancer research and drug delivery systems.

Research Focus šŸ”¬

Sayoni’s research expertise encompasses nanomedicine, biotechnology, tumor-targeted drug delivery, and cancer biology. She is dedicated to developing innovative therapeutic strategies, including subcellular targeting and pharmaceutical biotechnology. Her work involves cell culture techniques, bio-imaging probes, and fluorescence microscopy, aiming to enhance cancer therapies and improve patient outcomes through advanced biomedical applications. Sayoni is committed to pushing the boundaries of scientific knowledge in her field.

Conclusion šŸ“

Sayoni Maitra Roy exemplifies the qualities of a promising researcher and educator in the field of biotechnology. Her impressive educational background, innovative research contributions, and commitment to mentoring make her a strong candidate for the Women Researcher Award. By addressing areas for improvement such as expanding her research focus and enhancing her public engagement, Sayoni can further amplify her impact in the scientific community. Supporting her recognition through this award will not only honor her achievements but also inspire other women in research and biotechnology to pursue their passions and overcome challenges in their careers.

Publications Top Notes

  • Kinetics of Nanomedicine in Tumor Spheroid as an In Vitro Model System for Efficient Tumor-Targeted Drug Delivery With Insights From Mathematical Models
    Year: 2021
    Authors: SM Roy, V Garg, S Barman, C Ghosh, AR Maity, SK Ghosh
    Journal: Frontiers in Bioengineering and Biotechnology 9, 785937

 

  • Overcoming the barriers of nuclear-targeted drug delivery using nanomedicine-based strategies for enhanced anticancer therapy
    Year: 2023
    Authors: SM Roy, V Garg, SP Sivaraman, S Barman, C Ghosh, P Bag
    Journal: Journal of Drug Delivery Science and Technology 83, 104408

 

  • TLR2 dimerā€specific ligands selectively activate protein kinase C isoforms in Leishmania infection
    Year: 2021
    Authors: A Mukherjee, S Roy, A Patidar, N Bodhale, J Dandapat, B Saha, A Sarkar
    Journal: Immunology 164 (2), 318-331

 

  • Amine as a bottom-line functionality on DDS surface for efficient endosomal escape and further subcellular targets
    Year: 2022
    Authors: SM Roy, S Barman, A Basu, T Ghatak, SK Pore, SK Ghosh, R Mukherjee
    Journal: Journal of Drug Delivery Science and Technology 71, 103303

 

  • 3D multicellular tumor spheroids used for in vitro preclinical therapeutic screening
    Year: 2023
    Authors: SM Roy, P Kishore, D Saha, P Ghosh, R Kar, S Barman, V Agrawal, A Roy
    Journal: Journal of Drug Delivery Science and Technology 86, 104636

 

  • Efficient synergistic antibacterial activity of Ī±-MSH using chitosan-based versatile nanoconjugates
    Year: 2023
    Authors: S Barman, A Chakraborty, S Saha, K Sikder, S Maitra Roy, B Modi
    Journal: ACS Omega 8 (14), 12865-12877

 

  • Acidic pH-Triggered Release of Doxorubicin from Ligand-Decorated Polymeric Micelles Potentiates Efficacy against Cancer Cells
    Year: 2023
    Authors: S Maitra Roy, S Barman, P Kishore, B Chatterjee, P Bag, T Ghatak
    Journal: ACS Applied Nano Materials 6 (20), 18988-18998

 

  • Credibility, Trauma, and the Law: Domestic Violence-Based Asylum Claims in the United States
    Year: 2022
    Authors: Not specified
    Journal: Feminist Legal Studies 30 (3), 255-280

 

  • Amine as a Bottom-Line Functionality on DDS Surface for Efficient Endosomal Escape and Further Subcellular Targets
    Year: Not specified
    Authors: AR Maity, SM Roy, S Barman, A Basu, T Ghatak, SK Pore, SK Ghosh
    Journal: Available at SSRN 4047638

 

 

Julien Olivet | Epigenetics | Young Scientist Award

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Dr.Julien Olivet | Epigenetics | Young Scientist Award

Dr Julien Olivet Rega Institute/KU Leuven Belgium

Julien Olivet is an exceptional candidate for the Young Scientist Award due to his innovative research in structural and chemical biology, leadership in managing research projects, and significant international recognition. His technical expertise, particularly in cryo-EM and drug discovery, stands out. Additionally, his commitment to teaching and science outreach is commendable. To strengthen his candidacy, he could emphasize the real-world impact of his research and diversify his research topics and publications. Overall, Julienā€™s achievements and contributions make him a highly deserving nominee for the award.

Publication profile

scholar

šŸŽ“ Education

PhD in Biochemistry, Molecular and Cellular Biology, Bioinformatics and ModelingUniversitĆ© de LiĆØge, Belgium (2015-2021)Thesis: Selective disruption of histone deacetylase complexes by small-molecule inhibitors.MSc in Chemistry of Life and NanomaterialsUniversitĆ© de Namur, Belgium (2013-2015)Thesis: Synthesis of alginate/SiO2-TiO2 hybrid material for cell encapsulation.BSc in ChemistryFacultĆ©s Universitaires Notre-Dame de la Paix, Namur, Belgium (2009-2013).High School Diploma in Mathematics, Sciences Institut Notre-Dame de Loverval, Belgium (2003-2009).

šŸ”¬ Research Experience

Postdoctoral Fellow, KU Leuven (09/2021-present),Focus: Cryo-EM structures of SIN3 histone deacetylase (HDAC) complexes, managing collaborations, drug design.Visiting Senior Scientist, UniversitĆ© de LiĆØge (09/2021-present)Focus: Inhibitors of SIN3 protein in HDAC complexes, drug screening, spin-off development.PhD Research Fellow, UniversitĆ© de LiĆØge (01/2021-06/2021)Focus: Small molecule screening pipelines, virus-host interactions.Visiting FRS-FNRS/WBI PhD Research Fellow, Harvard Medical School (11/2015-12/2020)
Focus: Chemical genetic selections, protein interaction assays.

šŸ† Honours and Awards

NSFC-FWO Collaboration Project Award (2024-2025),Research Foundation Flanders (FWO), Belgium.McKinsey & Company Scientific Award (2022)EUR 5000.Marie Skłodowska-Curie Actions (MSCA) European Postdoctoral Fellowship (2022-2024),EUR 191760.Best Oral Presentation Award (2019)Dana-Farber Cancer Institute, USA.

Publication

  • Maximizing binary interactome mapping with a minimal number of assays
    • Authors: SG Choi, J Olivet, P Cassonnet, PO Vidalain, K Luck, L Lambourne, …
    • Year: 2019
  • The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
    • Authors: C Vandermeulen, T Oā€™Grady, J Wayet, B Galvan, S Maseko, M Cherkaoui, …
    • Year: 2021
  • Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells
    • Authors: D Kerselidou, BS Dohai, DR Nelson, S Daakour, N De Cock, …
    • Year: 2021
  • A systematic approach to identify host targets and rapidly deliver broad-spectrum antivirals
    • Authors: J Olivet, SB Maseko, AN Volkov, K Salehi-Ashtiani, K Das, …
    • Year: 2022
  • AI-guided pipeline for proteinā€“protein interaction drug discovery identifies a SARS-CoV-2 inhibitor
    • Authors: P Trepte, C Secker, J Olivet, J Blavier, S Kostova, SB Maseko, I Minia, …
    • Year: 2024
  • Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
    • Authors: SB Maseko, Y Brammerloo, I Van Molle, A Sogues, C Martin, C Gorgulla, …
    • Year: 2023
  • A quantitative mapping approach to identify direct interactions within complexomes
    • Authors: P Trepte, C Secker, SG Choi, J Olivet, ES Ramos, P Cassonnet, S Golusik, …
    • Year: 2021
  • Expanding the HDAC druggable landscape beyond enzymatic activity
    • Authors: J Olivet, SG Choi, S Sierra, TM O’Grady, M de la Fuente Revenga, F Laval, …
    • Year: 2023
  • Interactome and structural basis for targeting the human T-cell leukemia virus Tax oncoprotein
    • Authors: SB Maseko, I Van Molle, K Blibek, C Gorgulla, J Olivet, J Blavier, …
    • Year: 2021
  • The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
    • Authors: C Vandermeulen, T Oā€™Grady, B Galvan, M Cherkaoui, A Desbuleux, …
    • Year: 2021
  • Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule
    • Authors: SB Maseko, I Van Molle, K Blibek, C Gorgulla, J Olivet, J Blavier, …
    • Year: 2021
  • Selective disruption of histone deacetylase complexes by small-molecule inhibitors of protein interactions
    • Author: J Olivet
    • Year: 2021

 

šŸ… Conclusion

Julien Olivet is a strong candidate for the Young Scientist Award due to his outstanding research achievements, leadership skills, and contributions to the scientific community. His innovative work in cryo-EM and drug discovery, combined with his active role in mentoring and outreach, aligns well with the criteria for the award. Addressing the areas for improvement, particularly in demonstrating the broader impact of his research and expanding his publication portfolio, could further solidify his candidacy.