Dr. Srijan Acharya | Molecular Pharmacology | Excellence in Research
Dr at St. Jude Childrenβs Research Hospital, United States
Srijan Acharya is a dedicated scientist with expertise in molecular pharmacology and cancer genomics. He is currently a Post-Doctoral Research Fellow at St. Jude Childrenβs Research Hospital, focusing on childhood cancer research. With 32 published scientific articles and a total citation count of over 385, his work has contributed significantly to biomarker discovery, receptor pharmacology, and immuno-oncology. His research aims to address therapeutic resistance in pediatric malignancies through small molecule screening. Srijan is fluent in English, Bangla, and Hindi, with basic knowledge of Korean.
Profile
π Education
PhD in Molecular Pharmacology from Chonnam National University, South Korea (2020). M.Sc. in Biotechnology from North South University, Bangladesh (2015). BPHRM in Pharmacy from East West University, Bangladesh (2012). His academic journey has provided a strong foundation in receptor pharmacology and molecular biology, guiding his transition into cancer research.
πΌ Experience
Post-Doctoral Research Fellow, Pharmacy Department, St. Jude Childrenβs Research Hospital, USA (2023-Present). Post-Doctoral Research Fellow, Pathology Department, Mitchell Cancer Institute, USA (2020-2023). Executive Officer, Research and Development, Square Pharmaceutical PLC, Bangladesh (2012-2013). His experience spans academia and industry, with a focus on cancer research, receptor signaling, and small molecule screening.
π Awards and Honors
Inducted into Sigma Xi, The Scientific Research Honor Society (2023). Recognized in Whoβs Who in America by Marquis (2023). Young Investigator Award at AACR conference by AAISCR (2022). Best Presenter Award from China Pharmaceutical University (2021). Global Scholarship from Chonnam National University, Korea (2015). These accolades reflect his significant contributions to molecular pharmacology and cancer research.
π¬ Research Focus
Srijanβs research primarily investigates the role of molecular signaling in cancer, focusing on the interaction of nicotine receptors with GPCRs and their impact on cancer progression. At St. Jude, his work focuses on childhood cancers, particularly Ewing sarcoma and rhabdomyosarcoma. He uses small molecule screening to discover potential therapeutic agents and aims to overcome therapeutic resistance in pediatric cancers.
Conclusion
Srijan Acharya is a highly accomplished and promising researcher whose contributions to cancer pharmacology and molecular biology are noteworthy. His interdisciplinary research approach, combined with his dedication to advancing pediatric oncology, positions him as a leader in the field. With continued mentorship and broader collaborative efforts, Acharya is well poised for even greater achievements, further solidifying his place as an influential scientist in the biomedical community.
πPublications
- Title: Unveiling the intracellular dynamics of Ξ±4Ξ²2 nAChR-mediated ERK activation through the interplay of arrestin, GΞ²Ξ³, and PKCΞ²II
Year: 2024
Authors: Dooti K, Acharya S, Wang S, Kim K.M.
- Title: Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer
Year: 2023
Authors: Acharya S, Anand S, Khan MA, Zubair H, Srivastava SK, Singh S, Singh AP
- Title: MYB exhibits racially disparate expression, clinicopathologic association, and predictive potential for biochemical recurrence in prostate cancer
Year: 2023
Authors: Md Khan, S Acharya, S Anand, F Sameeta, P Pramanik, C Keel, S Singh, James E Carter, S Dasgupta, A Singh
- Title: Comparative study of the molecular mechanisms underlying the G protein and Ξ²-arrestin-dependent pathways that lead to ERKs activation upon stimulation by dopamine D2 receptor
Year: 2023
Authors: Liu H, Acharya S, Sudan SK, Hu L, Wu C, Cao Y, Li H, Zhang X
- Title: Frequent loss of cacna1c, a calcium voltage-gated channel subunit is associated with lung adenocarcinoma progression and poor prognosis
Year: 2023
Authors: Dasgupta, S., Acharya, S., Khan, M. A., Pramanik, P., Marbut, S. M., Yunus, F., Galeas, J. N., Singh, S., Singh, A. P., and Dasgupta, S.
- Title: Nicotine causes alternative polarization of macrophages via Src-mediated STAT3 activation: Potential pathobiological implications
Year: 2022
Authors: Acharya S, Saranyutanon S, Deshmukh SK, Khan MA, Singh S, Singh AP
- Title: Ξ²-Arrestin1 and GRK2 play permissive roles in Src-mediated endocytosis of Ξ±4Ξ²2 nicotinic acetylcholine receptor
Year: 2021
Authors: Acharya S, Kundu D, Kim KM
- Title: Roles of the Functional Interaction between Brain Cholinergic and Dopaminergic Systems in the Pathogenesis and Treatment of Schizophrenia and Parkinsonβs Disease
Year: 2021
Authors: Acharya S, Kim KM
- Title: Clinicopathologic significance and race-specific prognostic association of MYB overexpression in ovarian cancer
Year: 2021
Authors: Miree, O., Srivastava, β¦Acharya S.et al.
- Title: Metabotropic signaling cascade involved in Ξ±4Ξ²2 nicotinic acetylcholine receptor-mediated PKCΞ²II activation
Year: 2020
Authors: Acharya S, D. Kundu, H.J. Choi, and K.M. Kim
- Title: Catalpol and Mannitol, Two Components of Rehmannia glutinosa, Exhibit Anticonvulsant Effects Probably via GABAA Receptor Regulation
Year: 2019
Authors: Acharya S, Kim M., Botanas C. J., Custodio R. J., Lee H. J., Sayson L. V., Kim H. J.
- Title: Design, synthesis and in vitro activity of 1,4-disubstituted piperazines and piperidines as triple reuptake inhibitors
Year: 2017
Authors: Paudel S, Acharya S, Yoon G, Kim K.M., & Cheon S.H.