Antonios Kousaxidis | Medicinal Chemistry | Best Researcher Award

 Mr. Antonios Kousaxidis | Medicinal Chemistry |Best Researcher Award

 Mr at School of Pharmacy, Aristotle University of Thessaloniki, Greece

A seasoned educator and researcher with extensive experience in physics, holding positions from Assistant to Associate Professor at IAU, Urmia, and Urmia University of Technology. Specialized in teaching a range of undergraduate to Ph.D. courses including Quantum Mechanics, Laser Physics, and Nonlinear Dynamical Systems. Proficient in Maple and Matlab programming with a strong background in finite element method analysis. Led impactful research projects in chaotic systems, cancer treatment, and national security, earning multiple awards including the Kharazmi Scientific Festival Second Prize. A recognized leader in academia with a commitment to advancing scientific knowledge and education.


  1. Scopus

🎓 Education:

Master’s Degree in Medicinal Chemistry: (9.85/10) from Departments of Chemistry, Medicine, Biological Applications and Technology, University of Ioannina, 45110, Ioannina, Greece. Bachelor’s Degree in Chemistry: (7.76/10) from Department of Chemistry, School of Sciences, University of Ioannina, 45110, Ioannina, Greece.

Personal Skills:

Synthetic Organic Chemistry and Biochemistry: Training in synthetic organic chemistry and biochemistry applied to drug design, with experience in several areas of synthetic methodology using retrosynthetic approaches. Metal-Based Coupling Reactions: Excellent knowledge and practice of metal-based coupling reactions in modern organic chemistry. Synthetic Routes Optimization: Training in synthetic routes optimization using one-pot reactions during master’s thesis. Analytical Methods: Proficient in NMR, IR, UV, and mass spectrometry for identifying organic compounds. Small Molecule Synthesis: Synthesis of small molecule organic compounds and isolation by recrystallization. Purification and Separation: Excellent knowledge and practice in chromatographic methods like column, preparative, and thin-layer chromatography for purifying and separating organic compounds. Biochemical Protocols: Good practice in using biochemical protocols for enzyme kinetics experiments. Drug Discovery Programs: Extensive experience in drug discovery programs, structure-based drug design, molecular docking, and SAR estimation models using in silico methods (Discovery Studio, Chimera, LigandScout, PyMOL, OpenBabel, ADMET). Scientific Manuscripts: Proficient in writing and preparing scientific manuscripts.

💻 Software Skills:

Office Suite (ECDL degree) – Word processing, spreadsheets, presentations, etc. Calculative and predictive programs like MestReNova, Topspin DataAnalysis, ChemDraw Ultra, MedChem Designer, and BioLoom.

Research Focus:

A. Kousaxidis primarily focuses on the design and synthesis of novel compounds with therapeutic potential, particularly targeting enzymes such as aldose reductase (ALR2) and protein tyrosine phosphatase 1B (PTP1B). The research also encompasses antimicrobial agents, lipoxygenase inhibitors, and therapeutic strategies for conditions like diabetes mellitus and sepsis.

Publications Top Notes 📝

  • A Molecular Hybridization Approach for the Design of Selective Aldose Reductase (ALR2) Inhibitors and Exploration of Their Activities Against Protein Tyrosine Phosphatase 1B (PTP1B)
    • Authors: Kousaxidis, A., Petrou, A., Rouvim, P., Nicolaou, I., Geronikaki, A.
    • Journal: Journal of Molecular Structure
    • Year: 2023
    • Volume: 1271
    • Article Number: 134116
    • Citations: 3
    • Summary: This study presents a hybridization approach to develop selective ALR2 inhibitors and investigates their potential activities against PTP1B, highlighting their dual therapeutic potential.


  • Design, Synthesis, and Pharmacological Evaluation of Indazole Carboxamides of N-Substituted Pyrrole Derivatives as Soybean Lipoxygenase Inhibitors
    • Authors: Lavrentaki, V., Kousaxidis, A., Theodosis-Nobelos, P., Koutsopoulos, K., Nicolaou, I.
    • Journal: Molecular Diversity
    • Year: 2023
    • Citations: 2
    • Summary: This paper discusses the synthesis and evaluation of novel indazole carboxamides, demonstrating significant inhibitory activity against soybean lipoxygenase.


  • N-Derivatives of (Z)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1H-indole-2-carboxylates as Antimicrobial Agents—In Silico and In Vitro Evaluation
    • Authors: Petrou, A., Geronikaki, A., Kartsev, V., Nicolaou, I., Vizirianakis, I.S.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Issue: 1
    • Article Number: 131
    • Citations: 4
    • Summary: This open-access article evaluates the antimicrobial activity of new N-derivatives, supported by both in silico and in vitro methods.


  • Non-acidic Bifunctional Benzothiazole-Based Thiazolidinones with Antimicrobial and Aldose Reductase Inhibitory Activity as a Promising Therapeutic Strategy for Sepsis
    • Authors: Kousaxidis, A., Kovacikova, L., Nicolaou, I., Stefek, M., Geronikaki, A.
    • Journal: Medicinal Chemistry Research
    • Year: 2021
    • Volume: 30
    • Issue: 10
    • Pages: 1837-1848
    • Citations: 13
    • Summary: This research explores benzothiazole-based thiazolidinones with dual activity, suggesting a promising approach for treating sepsis.


  • Aldose Reductase and Protein Tyrosine Phosphatase 1B Inhibitors as a Promising Therapeutic Approach for Diabetes Mellitus
    • Authors: Kousaxidis, A., Petrou, A., Lavrentaki, V., Nicolaou, I., Geronikaki, A.
    • Journal: European Journal of Medicinal Chemistry
    • Year: 2020
    • Volume: 207
    • Article Number: 112742
    • Citations: 39
    • Summary: This review highlights the potential of targeting ALR2 and PTP1B as a therapeutic strategy for diabetes, emphasizing recent advances and future perspectives.


Pallab Mandal | Jadavpur University.

Pallab Mandal :Leading Researcher in Jadavpur University.

👨‍🏫 Pallab Mandal , an Mr at Jadavpur University. stands as a distinguished academic and researcher in the  Management and Accounting. Holding PhD Scholar: Pursuing from Jadavpur University Master of Pharmacy: Jadavpur University (2019), India. 🌟Pallab Mandal is a dedicated professional with extensive experience in bio-analytical method development, scientific/medical writing, and profound expertise in breast cancer research. His journey showcases a robust background in pharmaceuticals, with a strong focus on bioequivalence studies, LC-MS/MS analysis, and pharmacokinetic investigations. He possesses a comprehensive skill set in analytical techniques, GLP compliance, and a track record of successful publications and awards in the pharmaceutical domain.

🌐 Professional Profiles:

🎓 Academic Background

PhD Scholar: Pursuing from Jadavpur University Master of Pharmacy: Jadavpur University (2019) ,Bachelor of Pharmacy: Jadavpur University (2015) ,Diploma in Pharmacy: Institute of Pharmacy, Kalyani (2009) Various other diplomas and certifications in related medical fields

🏢 Work Experience

BioAnalyst LC-MS/MS and Head of Quality Assurance: Taab BioStudy Services, Jadavpur (July 2023 – Present)Senior BioAnalyst LC-MS/MS (Lab Incharge): Taab BioStudy Services, Jadavpur (Aug 2015 – July 2023)Teaching experience at Bio-equivalence study center, Jadavpur University (2018 – Present) Pharmacist roles in renowned healthcare facilities.

🏅 Achievements

National Award: M.N. DEV Memorial Award for outstanding performance in D.Pharm final exam International Scientist Award: Recognized as the Best Researcher at INSO Award for Engineering, Science, and Medicine Various awards and accolades for published research papers

🔬 Research & Publications

Diverse research projects focused on bioanalytical method development, pharmacokinetic studies, and drug analysis in human plasma Author of numerous research papers in esteemed national and international journals

📚 Skills & Competencies

Proficient in analytical method development for drug determination in tablets and plasma using HPLC, LC-MS/MS, and various analytical software Expertise in GLP maintenance, validation of developed methods, and analysis of pharmacokinetic data Industrial exposures, workshops, and training in pharmaceutical analysis

Top Noted Publication:

Simultaneous determination and quantitation of diosmetin and hesperetin in human plasma by liquid chromatographic mass spectrometry with an application to pharmacokinetic studies Published on 2019/5/1 Cited by 12

A critical insight of modern herbal drugs therapy under the purview of toxicity and authenticity Published on 2018 Cited by 12

Determination and quantitation of benzofuran, Indole and piperazine containing selective serotonin reuptake inhibitor vilazodone hydrochloride in human plasma by LC-ESI-MS/MS … Published on 2021 Cited by 7

LC-MS/MS method development and validation of an antihistaminic, calcium channel blocker, di-phenyl-methyl-piperazine group containing cinnarizine in human plasma with an …Published on 2018 cited by 5

Repeated dose toxicity study in rats of the formulation containing metformin and sitagliptin using microwave assisted acrylamide grafted cassia tora as polymer Published on 2016/6/1 Cited by 4

Analytical method development and validation of trimethylazanium containing anti-leishmanial phospholipid drug miltefosine by liquid chromatography quadruple tandem mass … Published on2016/6/1 Cited by 4

Microwave Assisted Acrylamide Grafting on a Natural Gum Cassia Tora: Characterization and Pharmacokinetic Evaluation of the Formulation Containing Metformin and Sitagliptin in …Published on 2022 Cited by 1

Anti-Hypertensive Activity of Some Selected Unani Formulations: An Evidence-Based Approach for Verification of Traditional Unani Claims Using LC-MS/MS for the Evaluation of … Published on 2022/8/8