Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

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Dr. Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

Dr at Medical University of ÅĆ³dÅŗ, Poland

Angelika Długosz-Pokorska, born on January 15, 1990, in ÅĆ³dÅŗ, Poland, is a Research Associate at the Medical University of ÅĆ³dÅŗ, specializing in medicinal chemistry and cancer research. She leads projects on anticancer compounds, opioid analogs, and their pharmacological effects, contributing to multiple EU-funded research initiatives.

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Education šŸŽ“

Angelika holds a Ph.D. in Medicinal Chemistry from the Medical University of ÅĆ³dÅŗ, Poland, and has undergone research training at the University of Rouen, France, in neuropsychopharmacology.

Experience šŸ§‘ā€šŸ«

With over 7 years of research experience, Angelika has served as Principal Investigator and Co-investigator for numerous projects, including anticancer activity studies and pharmacological analysis of synthetic peptides and compounds. She has also supervised and mentored young researchers and students.

Awards and Honors šŸ†

Angelika has received multiple accolades, including “Skuteczna Kobieta Roku 2021” (Effective Woman of the Year) in the Science category, Rector’s Awards for outstanding publications, and a First-level Special Award for Didactic Excellence.

Research Focus šŸ”

Angelikaā€™s research focuses on the development of new hybrid anticancer agents, including those with uracil skeletons and methylene groups. Her work also explores the role of endomorphin analogs in neuroprotection and cancer treatment.

Publications šŸ“š

 

  • “Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluationā€”Part I”
    • Journal: Materials
    • Date: February 15, 2024
    • DOI: 10.3390/ma17040899
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides”
    • Journal: Pharmaceuticals
    • Date: November 4, 2023
    • DOI: 10.3390/ph16111560
    • ISSN: 1424-8247
    • Contributors: Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells”
    • Journal: Biologics: Targets and Therapy
    • Date: May 2023
    • DOI: 10.2147/btt.s405080
    • ISSN: 1177-5491
    • Contributors: Angelika Długosz-Pokorska, Renata Perlikowska, Tomasz Janecki, Anna Janecka

 

  • “Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics”
    • Journal: Materials
    • Date: March 11, 2022
    • DOI: 10.3390/ma15062068
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Joanna Pacuła-Miszewska, Angelika Długosz-Pokorska, Anna Janecka, Andrzej Wojtczak, Jacek Scianowski

 

  • “A New Hybrid Ī“-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells”
    • Journal: Molecules
    • Date: 2020
    • DOI: 10.3390/molecules25071479
    • ISSN: 1420-3049
    • Contributors: Katarzyna Gach-Janczak, Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Rafał Jakubowski, Tomasz Janecki, Jacek Szymański, Anna Janecka

 

  • “New Uracil Analog U-332 is an Inhibitor of NF-ĪŗB in 5-Fluorouracil-Resistant Human Leukemia HL-60 Cell Line”
    • Journal: BMC Pharmacology & Toxicology
    • Date: 2020
    • DOI: 10.1186/s40360-020-0397-4
    • ISSN: 1471-2210
    • Contributors: Angelika Długosz-Pokorska, Marlena Pięta, Jacek Kędzia, Tomasz Janecki, Anna Janecka

 

  • “New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents”
    • Journal: Anti-Cancer Agents in Medicinal Chemistry
    • Date: 2020
    • DOI: 10.2174/1871520619666191211104128
    • ISSN: 1871-5206
    • PMID: 31823706
    • Contributors: Angelika Długosz-Pokorska, Joanna Drogosz-Stachowicz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski, Anna Janecka

 

  • “Seleninic Acid Potassium Salts as Water-Soluble Biocatalysts with Enhanced Bioavailability”
    • Journal: Materials
    • Date: 2020
    • DOI: 10.3390/ma13030661
    • ISSN: 1996-1944
    • PMID: 32024274
    • Contributors: Magdalena Obieziurska, Agata J. Pacuła, Anna Laskowska, Angelika Długosz-Pokorska, Anna Janecka, Jacek Ścianowski

 

  • “Molecular Mechanisms of Apoptosis Induced by a Novel Synthetic Quinolinone Derivative in HL-60 Human Leukemia Cells”
    • Journal: Chemico-Biological Interactions
    • Date: April 2020
    • DOI: 10.1016/j.cbi.2020.109005
    • ISSN: 0009-2797
    • Contributors: Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Agata Jaskulska, Tomasz Janecki, Anna Janecka

 

  • “Anticancer Activity of New Ī±-Methylene-Ī“-Lactone DL-247 in Selected Cancer Cell Lines”
    • Type: Conference Paper
    • Date: 2019
    • ISBN: 978-80-907442-0-2
    • Contributors: Katarzyna Gach-Janczak, Angelika Długosz-Pokorska, Joanna Drogosz, R. Jakubowski, Jacek Szymański, Tomasz Janecki, Anna Janecka

 

 

 

Moges Wordofa | Clinical Laboratory Science | Best Researcher Award

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Mr. Moges Wordofa | Clinical Laboratory Science | Best Researcher Award

Mr at Addis Ababa University, Ethiopia

Moges Wordofa, an Ethiopian national born on September 15, 1987, serves as a Lecturer at Addis Ababa University’s College of Health Science, Department of Medical Laboratory Science. With expertise in clinical laboratory science, he supervises students, conducts research projects, and advises both undergraduate and postgraduate students. Moges has a Master of Science in Clinical Laboratory Science from Addis Ababa University and a Bachelor of Science in Medical Laboratory Technology from the University of Gondar. He has published extensively and actively participates in community service and professional development. His research focuses include epidemiology, hematology, and infectious diseases.

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šŸŽ“ Education and Training

Bachelor of Science in Medical Laboratory Technology University of Gondar, Ethiopia, 2006 – 2009 Final Grade: 3.47. Master of Science in Clinical Laboratory Science (Hematology and Immunohematology) Addis Ababa University, Ethiopia, 2015 – 2017 Final Grade: 3.9 Thesis: Excellent. Certifications and Training Training of Trainers on Malaria Laboratory Diagnostic and Quality Assessment Ethiopian Public Health Institute and ICAP-Columbia University, 2015. Certificate of Appreciation for Participation on Flow Cytometry in Hematopathology, Transfusion Medicine, Peripheral Blood Morphology Training St Paulā€™s Hospital Medical Laboratory and Resolute Health, 2019. Certificate of Competency for Teaching in Higher Education Institutions Addis Ababa University, 2016. Excel Skills for Data Analytics and Visualization Macquarie University, Sydney, Australia, 2023

šŸ† Honours and Awards

Certificate of Award in Reviewing Journal of Advances in Medicine and Medical Research, 2021. Certificate of Award for Winning the Grand Prize in COVID-19 Clinical Cases Sharing Contest HemaTalk Webinar on COVID-19, Mindray International, 2021

Publication:šŸ“

 

  • Title: Establishing reference intervals for common hematology test parameters from apparently healthy geriatrics in Asella town, Southeast Ethiopia, 2020: a community-based cross-sectional study
    Authors: Hashim Harka, M., Siraj, Z., Dibaba, B., Tsegaye, A., Wordofa, M.
    Journal: Frontiers in Medicine
    Year: 2024
    Volume: 11
    Article ID: 1373283
    Citations: 0

 

  • Title: Helicobacter pylori (H. pylori) risk factor analysis and prevalence prediction: a machine learning-based approach
    Authors: Tran, V., Saad, T., Tesfaye, M., Ay, A., Taye, B.
    Journal: BMC Infectious Diseases
    Year: 2022
    Volume: 22
    Issue: 1
    Article ID: 655
    Citations: 8

 

  • Title: Machine learning-based risk factor analysis and prevalence prediction of intestinal parasitic infections using epidemiological survey data
    Authors: Zafar, A., Attia, Z., Tesfaye, M., Ay, A., Taye, B.
    Journal: PLoS Neglected Tropical Diseases
    Year: 2022
    Volume: 16
    Issue: 6
    Article ID: e0010517
    Citations: 9

 

  • Title: A comparative study of hematological parameters between hypertensive and normotensive individuals in Harar, eastern Ethiopia
    Authors: Sileshi, B., Urgessa, F., Wordofa, M.
    Journal: PLoS ONE
    Year: 2021
    Volume: 16
    Issue: 12
    Article ID: e0260751
    Citations: 7

 

  • Title: Intestinal helminthic infection and allergic disorders among school children enrolled in mass deworming program, Sululta, Ethiopia
    Authors: Abera, D., Wordofa, M., Mesfin, A., Tsegaye, A., Taye, B.
    Journal: Allergy, Asthma and Clinical Immunology
    Year: 2021
    Volume: 17
    Issue: 1
    Article ID: 43
    Citations: 1

 

  • Title: Blood coagulation parameter abnormalities in hospitalized patients with confirmed COVID-19 in Ethiopia
    Authors: Araya, S., Mamo, M.A., Tsegay, Y.G., Cheru, M., Tamir, Z.
    Journal: PLoS ONE
    Year: 2021
    Volume: 16
    Issue: 6
    Article ID: e0252939
    Citations: 26

 

  • Title: The magnitude of hematological abnormalities among COVID-19 patients in Addis Ababa, Ethiopia
    Authors: Araya, S., Wordofa, M., Mamo, M.A., Cheru, M., Tamir, Z.
    Journal: Journal of Multidisciplinary Healthcare
    Year: 2021
    Volume: 14
    Pages: 545ā€“554
    Citations: 17

 

Thi Mong Diep Nguyen | Molecular Biology | Best Researcher Award

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Assoc Prof Dr. Omvir Singh| Molecular Biology | Best Researcher Award

šŸ”¬šŸ§¬ Holding a Doctor of Science in Life Science (Cell Biotechnology) from the University of Tours, France, I’ve delved into diverse realms including cell biology, microbiology, and animal reproduction. As a Visiting Professor at the University of FranƧois-Rabelais and an Associate Professor at Quy Nhon University, I’ve led research projects exploring avian reproductive biotechnologies and the impact of AMPK protein kinase on male gonad functions. My contributions to grants investigating hCG glycoforms and fertility treatments showcase my dedication to advancing scientific understanding. šŸŒ±šŸ‘Øā€šŸ”¬

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Training Background:

University of Tours, France Years: 4/2022 Major/ Specialty: Life Science (Cell biotechnology) Academic Degree: Doctor of Science University of FranƧois-Rabelais, Tours, France Years: 1/2020 – 3/2020 Major/ Specialty: Biotechnology Role: Visiting Professor Quy Nhon University Year: 1/2020 Major/ Specialty: Biotechnology Role: Associate Professor INRA _Institut national de la recherche agronomique (Nouzilly), France Years: 10/2018 – 2/2019, 11/2016 – 04/2017 Major/ Specialty: Animal Cell Biotechnology + Immunology + Gonadotropins Role: Postdoctoral Researcher FranƧois-Rabelais University, France Years: 11/2011 – 10/2015 Major/ Specialty: Life Science (Cell biotechnology) Academic Degree: Ph.D Quy Nhon University Years: 9/2005 – 6/2008 Major/ Specialty: Biology Academic Degree: Master Quy Nhon University Years: 9/2001 – 9/2005 Major/ Specialty: Biology Academic Degree: Bachelor

 

šŸ”Research Projects (Last 5 Years):

CRYOBIRD – Development of avian reproductive biotechnologies for the management of genetic diversity Years: 10/2010 – 10/2014 Funding Institution: France Role: Participant. Study on pathogenic microorganisms in Arachis Hypogaea L. in ecological condition of Hoai An district, Binh Dinh province Year: 2016 – 2017 Funding Institution: Quy Nhon University Role: Chairman Impact of AMPK protein kinase on male gonad and spermatozoa functions Years: 2018 – 2019 Funding Institution: Quy Nhon University Role: Chairman Characterization of new hCG glycoforms for implantation and early pregnancy diagnostic Years: 2017 – 2020 Funding Institution: France Role: Participant Investigation on the role of 5ā€™-AMP activated protein kinase (AMPK) in adenylate cyclase gene expression using pharmacologicals activators and human Luteinizing Hormone (hLH) or Forskolin stimulators in Leydig MLTC-1 cells Years: 2018 – 2020 Funding Institution: NAFOSTED Role: Chairman Production of single-chain gonadotropins for fertility treatments Years: 2020 – 2023 Funding Institution: VINIF Role: Chairman

Publications Top Notes šŸ“

  1. Highly-Sensitive In Vitro Bioassays for FSH, TSH, PTH, Kp, and OT in Addition to LH in Mouse Leydig Tumor Cell
    • Authors: Klett, D., Pellissier, L., Lomet, D., Jean-Alphonse, F., Combarnous, Y.
    • Year: 2023

 

  1. Undissociable chemically cross-linked and single-chain gonadotropins
    • Authors: Nguyen, T.M.D., Klett, D., Combarnous, Y.
    • Year: 2023

 

  1. Impact of microwave synthesis time on the shape of silver nanostructures and their antibacterial activity
    • Authors: Hoang, N.H., Nguyen, V.N., Nguyen, T.T., Nguyen, T.M.D.
    • Year: 2023

 

  1. Natural and recombinant equine chorionic gonadotropins past and future in animal reproductive technology
    • Authors: Thach, D.T., Cuong, B.K., Van Tong, H., Combarnous, Y., Nguyen, T.M.D.
    • Year: 2022

 

  1. Effect of fluoxetine on cyclic adenosine monophosphate response to follicle-stimulating hormone in HEK cells
    • Authors: Nguyen, T.T., Nguyen, T.M.D.
    • Year: 2022

 

  1. Membrane Hormone Receptors and Their Signaling Pathways as Targets for Endocrine Disruptors
    • Authors: Combarnous, Y., Nguyen, T.M.D.
    • Year: 2022

 

  1. Roles of Soluble Adenylyl Cyclase in cAMP Synthesis in Animal Cells
    • Author: Nguyen, T.M.D.
    • Year: 2022

 

Hyun Suk Shin | Molecular Biology | Best Researcher Award

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Ā Dr. Hyun Suk Shin | Molecular Biology | Best Researcher Award

Ā Dr. University of Las Palmas de Gran Canaria,Ā  Spain

šŸ‘©ā€šŸ”¬ Hyun Suk Shin is a Marine Biotechnology expert with a rich academic background. She holds a B.Sc., M.Sc., and Ph.D. from Korea Maritime and Ocean University, where she delved into various aspects of aquaculture, molecular biology, and biochemistry. With extensive research experience, including international collaborations, she has contributed significantly to the field, resulting in numerous publications and patents. As a postdoctoral researcher, she continued her impactful work at institutions like the National Fisheries Research and Development Institute of Korea and the FundaciĆ³n Canaria Parque CientĆ­fico TecnolĆ³gico de la Universidad de Las Palmas de Gran Canaria. Recognized for her excellence, she received prestigious scholarships and awards, demonstrating her dedication to advancing aquaculture research.

 

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Education šŸ“š

  1. Higher Degree
    • Name of Qualification: M.S. Science
    • Degree Awarding Entity: Korea Maritime and Ocean University
    • Date of Qualification: 28/02/2010
  2. Higher Degree
    • Name of Qualification: B.S. Science, Marine Biotechnology
    • Degree Awarding Entity: Korea Maritime and Ocean University
    • Date of Qualification: 28/02/2008

Doctorates

  • PhD Science
    • Degree Awarding Entity: Korea Maritime and Ocean University
    • Date of Degree: 28/02/2014

Teaching ExperiencešŸ“Š

Experience Supervising Doctoral Theses and/or Final Year Projects: Project Title: Analysis of Skeletal Deformities in Gilthead Sea Bream Entity: Universidad de las Palmas de Gran Canaria Type of Entity: University Student: Alvaro Lorenzo Felipe Date of Reading: 05/07/2022Project Title: Programa Mejora GenĆ©tica en CamarĆ³n Entity: Universidad de las Palmas de Gran Canaria Type of Entity: University

 

Scientific or Technological Activities šŸ”¬

R&D Projects Funded Through Competitive Calls of Public or Private Entities

  1. Project Name: AquaIMPACT: Genomic and Nutritional Innovation for Genetically Superior Farmed Fish

Keywords: Molecular markers and recognition; Genetics transcription; Genetics expression of regulations; Epigenetics; Genetic drift; Population geneticsType of Project: Research and development, including transferGeographical Area: European UnionDegree of Contribution: ResearcherEntity: Universidad de las Palmas de Gran CanariaType of Entity: UniversityCity of Entity: Las Palmas de Gran Canaria, Canary Islands, SpainPrincipal Investigators: Daniel Montero VĆ­torres; Marisol Izquierdo Lopez; Juan Manuel Afonso Lopez; Maria Jesus Zamorano Serrano; Silvia Torrecillas Burriel; Hyun Suk Shin; Cathaysa PĆ©rez GarcĆ­aNumber of Researchers: 72Number of People/Year: 14Type of Participation: Team memberProgramme Name: Horizon 2020 Research and InnovationCode: 818367Start-End Date: 01/01/2018 – 02/01/2023Duration: 5 yearsParticipating Entities: [List of entities involved]Total Amount: ā‚¬6,100,000Sub-Project Amount: ā‚¬702,913Percentage as Grant: 100%Relevant Results: Determining the additive genetic components of immune system traits of sea bream and sea bass populations under genetic selection pressure for growth.Dedication Regime: Part-timeApplicant’s Contribution: In this project, my contribution is assigned within the WP2: Nutritional Innovation: Precision nutrition for superior genotypes, through the following tasks:Evaluation and divergent selection of sea bream breeders for growth and absence of skeletal deformities.Breeding, marking, fattening, and characterization of offspring and breeders using microsatellite markers “SMsa-1/ SMsa-2”.Study of genetic parameters of immune system traits.

Project Name: PerformFISH – Consumer Driven Production: Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chain

Keywords: Genetics expression of regulations; Genetic drift; Population geneticsType of Project: Research and development, including transferGeographical Area: European Union[Include any additional information about the project here]

Publications Top Notes šŸ“

  • Effects of LED light spectra on oxidative stress and the protective role of melatonin in relation to the daily rhythm of the yellowtail clownfish, Amphiprion clarkii
    • Authors: HS Shin, J Lee, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Year: 2011

 

  • Effect of LED light spectra on starvation-induced oxidative stress in the cinnamon clownfish Amphiprion melanopus
    • Authors: CY Choi, HS Shin, YJ Choi, NN Kim, J Lee, GS Kil
    • Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Year: 2012

 

  • Kisspeptin regulates the hypothalamusā€“pituitaryā€“gonad axis gene expression during sexual maturation in the cinnamon clownfish, Amphiprion melanopus
    • Authors: NN Kim, HS Shin, YJ Choi, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
    • Year: 2014

 

  • Effects of LED light spectra on the growth of the yellowtail clownfish Amphiprion clarkii
    • Authors: HS Shin, J Lee, CY Choi
    • Journal: Fisheries Science
    • Year: 2012

 

  • Profiles of antioxidant gene expression and physiological changes by thermal and hypoosmotic stresses in black porgy (Acanthopagrus schlegeli)
    • Authors: KW An, NN Kim, HS Shin, GS Kil, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Year: 2010

 

  • The effects of quercetin on physiological characteristics and oxidative stress resistance in olive flounder, Paralichthys olivaceus
    • Authors: HS Shin, JH Yoo, TS Min, KY Lee, CY Choi
    • Journal: Asian-Australasian Journal of Animal Sciences
    • Year: 2010

 

  • Selection for growth is associated in gilthead sea bream (Sparus aurata) with diet flexibility, changes in growth patterns and higher intestine plasticity
    • Authors: E Perera, P SimĆ³-Mirabet, HS Shin, E Rosell-Moll, F Naya-CatalĆ”, …
    • Journal: Aquaculture
    • Year: 2019

 

  • Quantitative mRNA expression of sox3 and DMRT1 during sex reversal, and expression profiles after GnRHa administration in black porgy, Acanthopagrus schlegeli
    • Authors: HS Shin, KW An, MS Park, MH Jeong, CY Choi
    • Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
    • Year: 2009

 

Yasaman Taslimi | diagnosis | Best Researcher Award

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Dr. Yasaman Taslimi | diagnosis| Autonomous systems | Best Researcher Award

Dr, Pasteur institute of Iran, Iran

šŸ‘©ā€šŸ”¬Ā Dedicated researcher with a Ph.D. in Biology from Pasteur Institute of Iran, specializing in molecular genetics and parasitology. šŸ§¬ Skilled in molecular diagnostics and protein analysis for Leishmaniasis. Currently serving as a Researcher in Immunotherapy and Leishmania Vaccine Research at Pasteur Institute, with extensive teaching and visiting researcher experience globally. Ā Recognized for academic excellence with awards including first rank in Ph.D. studies. Passionate about advancing immunotherapy and infectious disease research, with notable presentations at international congresses and a diverse range of specialized courses attended.šŸŒŸ

Profile

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Education šŸ“š

B.Sc. in Nutrition Azad University, Tehran, Iran 2000, M.Sc. in Biochemistry Azad University, Damghan, Iran 2015, PhD in Biology Pasteur Institute of Iran 2023

Position šŸ’¼

  • Researcher in Immunotherapy and Leishmania Vaccine Research Department
    Pasteur Institute of Iran
    2000-Present

Area of Expertise šŸ§¬

  • Molecular genetics, molecular parasitology, gene function and expression.
  • Molecular diagnosis of Leishmaniasis.
  • Arginase assay.
  • Protein analysis techniques such as Western Blot, Elisa.
  • PEA assay.
  • LAMP assay.

Courses šŸŽ“

Molecular DATA for infectious disease, ITM, Antwerp, Belgium, 2018International Workshop of Leishmania and Leishmaniasis, Pasteur Iran, 2016Molecular Biology of Leishmaniasis, ICGEB, Trieste, Italy, 2016.Targeting and Expression of Gene in Cells, International Congress of Immunology, Tehran, 2014How to write an International Article, Elsevier workshop, Tehran, 2014Application of Bioinformatics in Biotechnology, Pasteur Iran, 2013Flow Cytometry workshop, Pasteur Iran, 2012Quality Control Management, Pasteur Iran, 2012Calibration methods and standards, Pasteur Iran, 2011Life skills courses (Depression, Anger management, Time management, …), Pasteur, 2010Advanced Molecular Genetic course, Pasteur Iran, 2006ICDL courses, 2006

Teaching šŸ“

High throughput technologies in translational immunology, Pasteur, Iran, 2022Western Blot, Practical, School of Pharmacy, Shahid Beheshti University, Tehran, Iran, 2016Immunology of infectious disease, Practical, Pasteur Iran, 2006

Visiting Researcher šŸŒ

Gothenburg University (Leishild-MATI RISE project), Department of Microbiology and Immunology at Institute of Biomedicine, 2019/02/26-2019/05/14Pasteur Institute of Paris (Leishild-MATI RISE project), Department of Molecular Parasitology and Signaling, 2023/12/17-2023/02/17

Congress Presentations šŸ—£ļø

International Congress of Dermatology, Cosmetics and Laser, Iran, Tehran, 2022.International congress of immunology, Iran, Ahvaz, 2021.The 17th International Congress of Immunology, Beijing, China, 2019.Molecular Biology of Leishmania course, Trieste, Italy, 2016.Annual Symposium of the Institut Pasteur International Network, Paris, 2015.6th Worldleish international congress, Toledo, Spain, 2017.

Awards šŸ†

The Second National Conference on New Cellular and Molecular, Iran, 2015.13th International Congress of Immunology and Allergy of Iran, Tabriz, 2015.First ranked Ph.D. student in Pasteur Institute of Iran, 2018.

Publications Top Notes šŸ“

  1. Title: Immunization with the hybrid protein vaccine, consisting of Leishmania major cysteine proteinases Type I (CPB) and Type II (CPA), partially protects against leishmaniasis
    Authors: A Zadeh-Vakili, T Taheri, Y Taslimi, F Doustdari, AH Salmanian, S Rafati
    Journal: Vaccine
    Volume: 22
    Issue: 15-16
    Pages: 1930-1940
    Year: 2004
    Citations: 81

 

  1. Title: Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen
    Authors: F Zahedifard, E Gholami, T Taheri, Y Taslimi, F Doustdari, N Seyed, …
    Journal: PLoS neglected tropical diseases
    Volume: 8
    Issue: 3
    Pages: e2751
    Year: 2014
    Citations: 79

 

  1. Title: Development of Novel Prime-Boost Strategies Based on a Tri-Gene Fusion Recombinant L. tarentolae Vaccine against Experimental Murine Visceral Leishmaniasis
    Authors: N Saljoughian, T Taheri, F Zahedifard, Y Taslimi, F Doustdari, …
    Journal: PLoS neglected tropical diseases
    Volume: 7
    Issue: 4
    Pages: e2174
    Year: 2013
    Citations: 75

 

  1. Title: Leishmania major heat shock protein 70 (HSP70) is not protective in murine models of cutaneous leishmaniasis and stimulates strong humoral responses in cutaneous and visceral ā€¦
    Authors: S Rafati, E Gholami, N Hassani, F Ghaemimanesh, Y Taslimi, T Taheri, …
    Journal: Vaccine
    Volume: 25
    Issue: 21
    Pages: 4159-4169
    Year: 2007
    Citations: 71

 

  1. Title: Cysteine proteinase type III is protective against Leishmania infantum infection in BALB/c mice and highly antigenic in visceral leishmaniasis individuals
    Authors: N Khoshgoo, F Zahedifard, H Azizi, Y Taslimi, MJ Alonso, S Rafati
    Journal: Vaccine
    Volume: 26
    Issue: 46
    Pages: 5822-5829
    Year: 2008
    Citations: 61

 

 

Flavia | Molecular Biology | Young Scientist Award

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Dr. Flavia| Molecular Biology | Young Scientist Award

šŸ‘Øā€šŸ«Profile Summary

Flavia Scoyni is a highly accomplished researcher in molecular medicine, specializing in non-coding RNAs and their role in neurodegenerative diseases like Alzheimer’s and ischemic stroke. With a Ph.D. from the University of Eastern Finland under the Marie Skłodowska-Curie Programme, Flavia has extensive experience in experimental techniques such as scRNA-seq, FACS, and animal modeling. Their work has been published in prestigious journals and recognized with numerous grants and fellowships. Flavia’s expertise in molecular biology, cell culture, and animal work, coupled with a strong track record of securing research funding, positions them as a valuable asset in the field of translational medicine.

šŸŒ Professional Profiles

šŸŽ“Education:

Ph.D. in Molecular Medicine University of Eastern Finland, Kuopio, Finland Duration: Dec 2017 – Feb 2024 Marie Skłodowska-Curie Programme in Genetics and Mechanisms in Translational Medicine (GENOMMED) Advisor: Prof. Tarja Malm Dissertation: “Unlocking the potential of non-coding RNAs in regulating neurodegeneration – a glimpse into Alzheimerā€™s disease and ischemic stroke pathophysiology.” Ph.D. secondment Aarhus University, Aarhus, Denmark Duration: Sept 2018 – Feb 201 Advisor: Assoc. Prof. Thomas B. Hansen Funded by Saastamoinen Foundation travel grant FELASA accreditationUniversity of Eastern Finland, Kuopio, Finland May 2017 Federation of Laboratory Animal Science Associations (FELASA) Certificate in laboratory animal science for EU Functions A/D MSc in Molecular Biology “Sapienza” University of Rome, Rome, Italy Duration: Oct 2013 – Dec 2015 Master Degree in Molecular Biology Graduated magna cum laude (110/110 cum laude) Advisor: Prof. Alessandro Fatica Thesis title: “Identification of new transcriptional targets of p30 C/EBPĪ± transcription factor isoform in acute myeloid leukemia” MSc in Genetics University Paris-Diderot VII, Paris, France Duration: Oct 2013 – June 2015 BSc in Biotechnology “Sapienza” University of Rome, Rome, Italy Duration: Oct 2010 – July 2013 Bachelor degree in Biotechnology Graduated magna cum laude (110/110 cum laude) Advisor: Prof. Carlo Presutti Thesis title: “The role of the mir-200 family in the regulation of the expression of AP1 transcriptional factor”

šŸ”¬Research Experience:

Early stage researcher Professor Tarja Malm University of Eastern Finland, A.I. Virtanen Institute for Molecular Sciences Jan 2017 ā€“ Dec 2017 Investigated the role of microRNAs in phagocytic microglia isolated from adult Alzheimerā€™s mice. Developed techniques including ex-vivo FACS, low input RNA extraction, cloning, qPCR, and protocol for transfection for hard-to-transfect cell lines. Conducted animal procedures to harvest brain samples or acutely isolate adult microglia. Erasmus traineeship Biotech Research & Innovation Centre, Copenhagen, Denmark Oct 2016 – June 2016 Developed a transgenic stable cell line for long non-coding RNAs. Applied techniques such as cloning of long inserts, lentiviral vector production, and stable cell line development. Master thesis Professor Alessandro Fatica “Sapienza” University of Rome, Rome, Italy June 2014 – Dec 2015 Investigated the regulation of the long non-coding RNA UCA1 mediated by C/EBPĪ± transcription factor in the K562 lymphoblast cell line. Applied techniques including ChIP, cloning, RNA extraction, RT-qPCR, WB, transfection, CRISPR-Cas9, and stable cell line development. Master Internship Professor Giuseppe Macino “Sapienza” University of Rome, Rome, Italy Sept 2013 – March 2014 Studied microRNAs inducing epigenetic modifications in mammals.Applied techniques such as ChIP, cloning, mutagenesis, RNA extraction, RT-qPCR, WB, CRISPR-Cas9, and stable cell line development. Bachelor thesis Professor Carlo Presutti “Sapienza” University of Rome, Rome, Italy Oct 2012 – July 2013 Investigated the role of the miR-200a family in regulating c-JUN transcription factor expression. Utilized techniques including cloning, mutagenesis, bacterial transformation, and cell line culture.

šŸ’» Technical Skills:

Molecular biology techniques such as scRNA-seq, RNA-seq, FACS, cloning, RT-qPCR, WB, lentiviral vectors generation. Cell culture techniques including neuronal culture, primary microglial culture, transduction, transfection, and stable cell line development. Animal work including FELASA A/D certification, maintenance, and breeding of transgenic mouse models, animal procedures, and tamoxifen-induced recombination. Statistical analysis, basic Python, and R.

šŸ†Fellowships, Awards, and Honors:

  • Secured total grants of 99.000ā‚¬ during Ph.D., including grants from Pavo Nuermen Foundation, Finnish Cultural Foundation, Kuopio University Foundation, and others.

šŸ‘©ā€šŸ« Teaching Experience:

  • Mentored a Ph.D. student and post-graduate student, and supervised five master’s thesis students during the Ph.D. program.

šŸ“šTop Noted Publication

  1. ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling
    • Journal: Cell Reports
    • Year: 2024-03
    • DOI: 10.1016/j.celrep.2024.113862
    • Contributors: Flavia Scoyni; Valeriia Sitnikova; Luca Giudice; Paula Korhonen; Davide M. Trevisan; Ana Hernandez de Sande; Mireia Gomez-Budia; Raisa Giniatullina; Irene F. Ugidos; Hiramani Dhungana et al.

 

  1. Alzheimer’s disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs
    • Journal: Alzheimer’s & Dementia
    • Year: 2024-02
    • DOI: 10.1002/alz.13502
    • Contributors: Flavia Scoyni; Luca Giudice; Mari-Anna VƤƤnƤnen; Nicholas Downes; Paula Korhonen; Xin Yi Choo; Nelli-Noora VƤlimƤki; Petri MƤkinen; Nea Korvenlaita; Annemieke J Rozemuller et al.

 

  1. ciRS-7 and miR-7 regulate ischemia induced neuronal death via glutamatergic signaling
    • Journal: Preprint
    • Year: 2023-01-24
    • DOI: 10.1101/2023.01.24.525136
    • Contributors: Flavia Scoyni; Valeriia Sitnikova; Luca Giudice; Paula Korhonen; Davide M Trevisan; Ana Hernandez de Sande; Mireia Gomez-Budia; Raisa Giniatullina; Irene F Ugidos; Hiramani Dhungana et al.

 

  1. Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation
    • Journal: Journal of Neuroinflammation
    • Year: 2020
    • DOI: 10.1186/s12974-020-01870-w
    • Contributors: Kolosowska, N.; Gotkiewicz, M.; Dhungana, H.; Giudice, L.; Giugno, R.; Box, D.; Huuskonen, M.T.; Korhonen, P.; Scoyni, F.; Kanninen, K.M. et al.

 

  1. PSEN1Ī”E9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia
    • Journal: Stem Cell Reports
    • Year: 2019
    • DOI: 10.1016/j.stemcr.2019.08.004
    • Contributors: Konttinen, H.; Cabral-da-Silva, M.E.C.; Ohtonen, S.; Wojciechowski, S.; Shakirzyanova, A.; Caligola, S.; Giugno, R.; Ishchenko, Y.; HernĆ”ndez, D.; Fazaludeen, M.F. et al.