Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

Dr. Angelika Długosz-Pokorska | Molecular biochemistry | Women Researcher Award

Dr at Medical University of Łódź, Poland

Angelika Długosz-Pokorska, born on January 15, 1990, in Łódź, Poland, is a Research Associate at the Medical University of Łódź, specializing in medicinal chemistry and cancer research. She leads projects on anticancer compounds, opioid analogs, and their pharmacological effects, contributing to multiple EU-funded research initiatives.

Profile

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Education 🎓

Angelika holds a Ph.D. in Medicinal Chemistry from the Medical University of Łódź, Poland, and has undergone research training at the University of Rouen, France, in neuropsychopharmacology.

Experience 🧑‍🏫

With over 7 years of research experience, Angelika has served as Principal Investigator and Co-investigator for numerous projects, including anticancer activity studies and pharmacological analysis of synthetic peptides and compounds. She has also supervised and mentored young researchers and students.

Awards and Honors 🏆

Angelika has received multiple accolades, including “Skuteczna Kobieta Roku 2021” (Effective Woman of the Year) in the Science category, Rector’s Awards for outstanding publications, and a First-level Special Award for Didactic Excellence.

Research Focus 🔍

Angelika’s research focuses on the development of new hybrid anticancer agents, including those with uracil skeletons and methylene groups. Her work also explores the role of endomorphin analogs in neuroprotection and cancer treatment.

Publications 📚

 

  • “Synthesis of New Chiral β-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluation—Part I”
    • Journal: Materials
    • Date: February 15, 2024
    • DOI: 10.3390/ma17040899
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides”
    • Journal: Pharmaceuticals
    • Date: November 4, 2023
    • DOI: 10.3390/ph16111560
    • ISSN: 1424-8247
    • Contributors: Agata Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Jastrzebska, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Jacek Scianowski

 

  • “New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells”
    • Journal: Biologics: Targets and Therapy
    • Date: May 2023
    • DOI: 10.2147/btt.s405080
    • ISSN: 1177-5491
    • Contributors: Angelika Długosz-Pokorska, Renata Perlikowska, Tomasz Janecki, Anna Janecka

 

  • “Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics”
    • Journal: Materials
    • Date: March 11, 2022
    • DOI: 10.3390/ma15062068
    • ISSN: 1996-1944
    • Contributors: Anna Laskowska, Agata Joanna Pacuła-Miszewska, Angelika Długosz-Pokorska, Anna Janecka, Andrzej Wojtczak, Jacek Scianowski

 

  • “A New Hybrid δ-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells”
    • Journal: Molecules
    • Date: 2020
    • DOI: 10.3390/molecules25071479
    • ISSN: 1420-3049
    • Contributors: Katarzyna Gach-Janczak, Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Rafał Jakubowski, Tomasz Janecki, Jacek Szymański, Anna Janecka

 

  • “New Uracil Analog U-332 is an Inhibitor of NF-κB in 5-Fluorouracil-Resistant Human Leukemia HL-60 Cell Line”
    • Journal: BMC Pharmacology & Toxicology
    • Date: 2020
    • DOI: 10.1186/s40360-020-0397-4
    • ISSN: 1471-2210
    • Contributors: Angelika Długosz-Pokorska, Marlena Pięta, Jacek Kędzia, Tomasz Janecki, Anna Janecka

 

  • “New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents”
    • Journal: Anti-Cancer Agents in Medicinal Chemistry
    • Date: 2020
    • DOI: 10.2174/1871520619666191211104128
    • ISSN: 1871-5206
    • PMID: 31823706
    • Contributors: Angelika Długosz-Pokorska, Joanna Drogosz-Stachowicz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski, Anna Janecka

 

  • “Seleninic Acid Potassium Salts as Water-Soluble Biocatalysts with Enhanced Bioavailability”
    • Journal: Materials
    • Date: 2020
    • DOI: 10.3390/ma13030661
    • ISSN: 1996-1944
    • PMID: 32024274
    • Contributors: Magdalena Obieziurska, Agata J. Pacuła, Anna Laskowska, Angelika Długosz-Pokorska, Anna Janecka, Jacek Ścianowski

 

  • “Molecular Mechanisms of Apoptosis Induced by a Novel Synthetic Quinolinone Derivative in HL-60 Human Leukemia Cells”
    • Journal: Chemico-Biological Interactions
    • Date: April 2020
    • DOI: 10.1016/j.cbi.2020.109005
    • ISSN: 0009-2797
    • Contributors: Joanna Drogosz-Stachowicz, Angelika Długosz-Pokorska, Katarzyna Gach-Janczak, Agata Jaskulska, Tomasz Janecki, Anna Janecka

 

  • “Anticancer Activity of New α-Methylene-δ-Lactone DL-247 in Selected Cancer Cell Lines”
    • Type: Conference Paper
    • Date: 2019
    • ISBN: 978-80-907442-0-2
    • Contributors: Katarzyna Gach-Janczak, Angelika Długosz-Pokorska, Joanna Drogosz, R. Jakubowski, Jacek Szymański, Tomasz Janecki, Anna Janecka