Antonios Kousaxidis | Medicinal Chemistry | Best Researcher Award

 Mr. Antonios Kousaxidis | Medicinal Chemistry |Best Researcher Award

 Mr at School of Pharmacy, Aristotle University of Thessaloniki, Greece

A seasoned educator and researcher with extensive experience in physics, holding positions from Assistant to Associate Professor at IAU, Urmia, and Urmia University of Technology. Specialized in teaching a range of undergraduate to Ph.D. courses including Quantum Mechanics, Laser Physics, and Nonlinear Dynamical Systems. Proficient in Maple and Matlab programming with a strong background in finite element method analysis. Led impactful research projects in chaotic systems, cancer treatment, and national security, earning multiple awards including the Kharazmi Scientific Festival Second Prize. A recognized leader in academia with a commitment to advancing scientific knowledge and education.


  1. Scopus

🎓 Education:

Master’s Degree in Medicinal Chemistry: (9.85/10) from Departments of Chemistry, Medicine, Biological Applications and Technology, University of Ioannina, 45110, Ioannina, Greece. Bachelor’s Degree in Chemistry: (7.76/10) from Department of Chemistry, School of Sciences, University of Ioannina, 45110, Ioannina, Greece.

Personal Skills:

Synthetic Organic Chemistry and Biochemistry: Training in synthetic organic chemistry and biochemistry applied to drug design, with experience in several areas of synthetic methodology using retrosynthetic approaches. Metal-Based Coupling Reactions: Excellent knowledge and practice of metal-based coupling reactions in modern organic chemistry. Synthetic Routes Optimization: Training in synthetic routes optimization using one-pot reactions during master’s thesis. Analytical Methods: Proficient in NMR, IR, UV, and mass spectrometry for identifying organic compounds. Small Molecule Synthesis: Synthesis of small molecule organic compounds and isolation by recrystallization. Purification and Separation: Excellent knowledge and practice in chromatographic methods like column, preparative, and thin-layer chromatography for purifying and separating organic compounds. Biochemical Protocols: Good practice in using biochemical protocols for enzyme kinetics experiments. Drug Discovery Programs: Extensive experience in drug discovery programs, structure-based drug design, molecular docking, and SAR estimation models using in silico methods (Discovery Studio, Chimera, LigandScout, PyMOL, OpenBabel, ADMET). Scientific Manuscripts: Proficient in writing and preparing scientific manuscripts.

💻 Software Skills:

Office Suite (ECDL degree) – Word processing, spreadsheets, presentations, etc. Calculative and predictive programs like MestReNova, Topspin DataAnalysis, ChemDraw Ultra, MedChem Designer, and BioLoom.

Research Focus:

A. Kousaxidis primarily focuses on the design and synthesis of novel compounds with therapeutic potential, particularly targeting enzymes such as aldose reductase (ALR2) and protein tyrosine phosphatase 1B (PTP1B). The research also encompasses antimicrobial agents, lipoxygenase inhibitors, and therapeutic strategies for conditions like diabetes mellitus and sepsis.

Publications Top Notes 📝

  • A Molecular Hybridization Approach for the Design of Selective Aldose Reductase (ALR2) Inhibitors and Exploration of Their Activities Against Protein Tyrosine Phosphatase 1B (PTP1B)
    • Authors: Kousaxidis, A., Petrou, A., Rouvim, P., Nicolaou, I., Geronikaki, A.
    • Journal: Journal of Molecular Structure
    • Year: 2023
    • Volume: 1271
    • Article Number: 134116
    • Citations: 3
    • Summary: This study presents a hybridization approach to develop selective ALR2 inhibitors and investigates their potential activities against PTP1B, highlighting their dual therapeutic potential.


  • Design, Synthesis, and Pharmacological Evaluation of Indazole Carboxamides of N-Substituted Pyrrole Derivatives as Soybean Lipoxygenase Inhibitors
    • Authors: Lavrentaki, V., Kousaxidis, A., Theodosis-Nobelos, P., Koutsopoulos, K., Nicolaou, I.
    • Journal: Molecular Diversity
    • Year: 2023
    • Citations: 2
    • Summary: This paper discusses the synthesis and evaluation of novel indazole carboxamides, demonstrating significant inhibitory activity against soybean lipoxygenase.


  • N-Derivatives of (Z)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1H-indole-2-carboxylates as Antimicrobial Agents—In Silico and In Vitro Evaluation
    • Authors: Petrou, A., Geronikaki, A., Kartsev, V., Nicolaou, I., Vizirianakis, I.S.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Issue: 1
    • Article Number: 131
    • Citations: 4
    • Summary: This open-access article evaluates the antimicrobial activity of new N-derivatives, supported by both in silico and in vitro methods.


  • Non-acidic Bifunctional Benzothiazole-Based Thiazolidinones with Antimicrobial and Aldose Reductase Inhibitory Activity as a Promising Therapeutic Strategy for Sepsis
    • Authors: Kousaxidis, A., Kovacikova, L., Nicolaou, I., Stefek, M., Geronikaki, A.
    • Journal: Medicinal Chemistry Research
    • Year: 2021
    • Volume: 30
    • Issue: 10
    • Pages: 1837-1848
    • Citations: 13
    • Summary: This research explores benzothiazole-based thiazolidinones with dual activity, suggesting a promising approach for treating sepsis.


  • Aldose Reductase and Protein Tyrosine Phosphatase 1B Inhibitors as a Promising Therapeutic Approach for Diabetes Mellitus
    • Authors: Kousaxidis, A., Petrou, A., Lavrentaki, V., Nicolaou, I., Geronikaki, A.
    • Journal: European Journal of Medicinal Chemistry
    • Year: 2020
    • Volume: 207
    • Article Number: 112742
    • Citations: 39
    • Summary: This review highlights the potential of targeting ALR2 and PTP1B as a therapeutic strategy for diabetes, emphasizing recent advances and future perspectives.


Monika Kopeć | medical chemistry | Young Scientist Award

Dr. Monika Kopeć | medical chemistry | Young Scientist Award

👨‍🏫Profile Summary

In 2018, I earned a doctorate in chemical science from the Faculty of Chemistry at Lodz University of Technology, specializing in the study of biological systems using spectroscopic techniques. Additionally, I completed a master’s program in logistics with a focus on supply chain management. With nine years of experience in chemistry, including managing research projects, I have honed my skills in team collaboration and project management. I have also undertaken various courses and workshops to enhance my expertise, including those in self-motivation, effective learning, and commercializing research. Now, I aim to further expand my knowledge and skills in research techniques and seek opportunities in leading chemical or logistics companies.

🌐 Professional Profiles

Educational Qualifications 📚

Postgraduate Studies in Data Analysis and Data Mining University of Lodz, Faculty of Mathematics and Computer Science October 2021 – June 2022 PhD Studies in Chemistry Lodz University of Technology, Faculty of Chemistry October 2013 – September 2018 Dissertation awarded by the Council of the Chemical Faculty of Lodz University of Technology Postgraduate Studies in Forensic Biology University of Lodz, Faculty of Biology October 2014 – March 2016 Masters Studies in Logistics with Major in Supply Chain Management University of Lodz, Faculty of Management October 2012 – July 2014 Masters Studies in Chemistry with Major in Medical Chemistry Lodz University of Technology, Faculty of Chemistry March 2012 – July 2013 Engineering Studies in Chemistry with Major in Chemical Analysis in Environmental Control and Quality Engineering Lodz University of Technology, Faculty of Chemistry October 2008 – January 2012 Biologically-Chemical Profile High Comprehensive School S. Żeromskiego in Ozorków September 2005 – June 2008

Work Experience 💼

Lecturer Lodz University of Technology October 2019 – Present Responsibilities include experimental analysis, conducting classes, and research documentation. Postdoctoral Fellowship Jagiellonian University in Krakow January 2023 – February 2023 Engineering and Technical Specialist Lodz University of Technology May 2019 – December 2021 Duties involved equipment preparation, chemical reagent management, and ordering. Assistant Lodz University of Technology October 2018 – October 2019 Conducted experimental analysis, classes, and research documentation. Chemist Lodz University of Technology October 2015 – November 2018 Prepared reagents, conducted spectroscopy measurements, and provided technical support. PhD Student Lodz University of Technology October 2013 – September 2018 Conducted measurements using spectroscopy techniques. Apprenticeships Institute of Polymer and Dye Engineering in Zgierz District Police Headquarters in Zgierz July 2011 – August 2011 / July 2010 – August 2010 Hostess Cursor S.A. Sales & Marketing Services August 2009 – September 2009 Trainee District Police Headquarters in Zgierz June 2008 – September 2008

Trainings and Workshops 🎓

AFM Modes Training: Contact, tapping, ScanAsyst, Resonance Enhanced AFM-IR, Tapping AFM-IR, and Micro View Dates: 05.12.2022 – 09.12.2022 Laboratory Procedures Training: Operation and proper use of equipment such as the CO2 incubator Memmert ICO150med, laboratory centrifuge MPW 260R with cooling, and laminar chamber II safety class ESCO AIRSTREAM type AC2-4EB Dates: 4.10.2022 – 6.10.2022 Techniques Training: SDS-PAGE, Western Blot, and visualization of protein gels using Comassie and Stain-Free methods Usage of the Mini-Protean Tetra Cell, Trans-Blot Turbo, and ChemiDoc MP systems Dates: 4.10.2022 – 6.10.2022 Microscope and Imaging Software Training: Use of the Leica DMiL LED inverted microscope, Leica FLEXACAM C1 camera, and Leica LAS X software Quick Reading and Effective Learning Methods Course Commercialization of Research and Establishing Cooperation with Industry Workshop Team Coaching Workshop: Motivating Members to Achieve Common Goals Zetasizer and Nanosight Analyzers Training for Particle Size Measurements Training on the Use of Nanomaterials in Nanomedicine and Bionanotechnology Self-Motivation and Team Motivation Workshop

Projects 🚀

Raman Imaging of Human Cancerous Tissue and Cell Cultures (2016) Function: Project Manager Identification of Tumor Changes Based on Imaging and Raman Spectroscopy (2019) Function: Project Contractor Raman Imaging and Endospectroscopy in Oncological Omic Studies (2020 – 2022) Function: Project Contractor Analysis of Angiogenesis Process in Human Breast Tissue Using Raman Spectroscopy (2020 – 2021) Function: Project Manager Influence of Sugars on Metabolism of Lung Cancer Cells (2022) Function: Project Manager The Triangle: Carotenoids-Retinoids-Cytochromes in Cancer Progression (2022 – Present) Function: Project Contractor

Awards 🏆

  • Various Scholarships and Rector’s Scholarships during PhD Studies (2014 – 2018)
  • Platinum Medal at International Warsaw Invention Show (2019)
  • Award of the Rector of the Medical University of Lodz (2019)
  • Award for Scientific Achievements in Spectroscopic Identification of Cancer Changes (2019)
  • Award Supporting Scientific Excellence under the “Initiative of Excellence – Research University” Program (2020, 2021)

📚Top Noted Publication

  1. Title: Revision of Commonly Accepted Warburg Mechanism of Cancer Development: Redox-Sensitive Mitochondrial Cytochromes in Breast and Brain Cancers by Raman Imaging
    • Authors: H. Abramczyk, J. Surmacki, B. Brozek-Pluska, M. Kopec
    • Journal: Cancers
    • DOI: 10.3390/cancers13112599
    • Publication Date: Unknown


  1. Title: Raman imaging and statistical methods for analysis various type of human brain tumors and breast cancers
    • Authors: M. Kopec, J. Surmacki, M. Błaszczyk, M. Radek, H. Abramczyk
    • Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
    • DOI: 10.1016/j.saa.2021.120091
    • Publication Date: 2021


  1. Title: The role of pro- and antiangiogenic factors in angiogenesis process by Raman spectroscopy
    • Authors: M. Kopec, H. Abramczyk
    • Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
    • DOI: 10.1016/j.saa.2021.120667
    • Publication Date: 2021


  1. Title: Double face of cytochrome c in cancers by Raman imaging
    • Authors: H. Abramczyk, B. Brożek-Płuska, M. Kopeć
    • Journal: Scientific Reports
    • DOI: Link
    • Publication Date: 2022


  1. Title: Analysis of eggs depending on the hens’ breeding systems by Raman spectroscopy


  1. Title: Decoding Breast Cancer Metabolism: Hunting BRCA Mutations by Raman Spectroscopy
    • Authors: M. Kopec, B. Romanowska-Pietrasiak, H. Abramczyk
    • Journal: Photochem
    • DOI: 10.3390/photochem2030048
    • Publication Date: 2022


  1. Title: Hyperglycemia and cancer in human lung carcinoma by means of Raman spectroscopy and imaging
    • Authors: M. Kopec, K. Beton, K. Jarczewska, H. Abramczyk
    • Journal: Scientific Reports
    • DOI: 10.1038/s41598-022-21483-y
    • Publication Date: 2022


  1. Title: Hemoglobin and cytochrome c. reinterpreting the origins of oxygenation and oxidation in erythrocytes and in vivo cancer lung cells
    • Authors: H. Abramczyk, J.M. Surmacki, M. Kopeć, K. Jarczewska, B. Romanowska-Pietrasiak
    • Journal: Scientific Reports
    • DOI: 10.1038/s41598-023-41858-z
    • Publication Date: 2023


  1. Title: Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming


  1. Title: The role of glucose and fructose on lipid droplet metabolism in human normal bronchial and cancer lung cells by Raman spectroscopy