Mr. Abdulwasiu Ibrahim | Drug Discovery | Young Scientist Award
Research Fellow, Drosophila Research and Training Centre Nigeria
Abdulwasiu Ibrahim is a biochemist specializing in cancer biology, molecular biology, and bioinformatics. He is affiliated with the Department of Biochemistry, University of Ibadan, Nigeria. His expertise spans drug discovery, precision medicine, pharmacogenomics, and toxicogenomics. Proficient in computational biology, he applies computer-aided drug design, immunoinformatics, and biochemical analytics to research. His technical skills include gel electrophoresis, ELISA, PCR, and spectroscopy. He has a strong background in statistical analysis using GraphPad Prism and Microsoft Excel, with foundational knowledge of Python. He has extensive research experience in genetic profiling and biological drug delivery. Currently, he is a Research Fellow at the Drosophila Research and Training Centre and a Research Associate at the Institute of Bioinformatics and Molecular Therapeutics. He has received multiple conference fellowships and published several high-impact research papers. His work contributes to advancing cancer treatment and precision medicine using bioinformatics and molecular biology approaches.
Publication Profile
๐ Education
Master of Science in Biochemistry (Cancer Research and Molecular Biology) โ University of Ibadan, Nigeria (2022โ2024) Thesis: Interactive Toxicity of 2-Acetylaminoflourene and Diethylnitrosamine in Drosophila melanogaster. Bachelor of Science in Biochemistry (Second Class Upper-Honours) โ Usmanu Danfodiyo University, Sokoto, Nigeria (2015โ2019)
Thesis: Analgesic Activity of n-Hexane Extract of Castor Seed on Formalin-Induced Pain in Albino Rats.
๐ผ Experience
Research Fellow โ Drosophila Research and Training Centre (2022โPresent) Designed and conducted Drosophila experiments, supervised students, and managed lab operations.. Research Associate (Volunteer) โ Institute of Bioinformatics and Molecular Therapeutics (2022โPresent) Developed computational models for drug discovery, performed molecular docking, and trained interns. Post-Graduate Research Assistant โ University of Ibadan (2022โ2024) Conducted molecular analysis of cancer markers and supervised undergraduate projects. Research Assistant โ Drosophila Laboratory, University of Ibadan (2021โ2022) Taught students Drosophila research techniques and performed oxidative stress biomarker analysis. Undergraduate Research Assistant โ Usmanu Danfodiyo University (2019โ2020) Conducted phytochemical screening, biochemical analysis, and systematic reviews. Tutorial Teacher โ Nigerian Society of Biochemistry Students (2019) Taught biochemistry, pharmacology, and molecular biology to undergraduate students.
๐ Awards & Honors
Conference Fellowships: 11th & 10th Conference of the Nigerian Institute of Medical Research (NIMR) (2022, 2021) 2nd Drug Discovery Africa International Conference (DDA) (2022) 2nd Conference of Nigerian Bioinformatics and Genomics Network (NBGN) (2021) 7th Unibadan Conference of Basic Medical Sciences (2021). Virtual Chair Award โ Midwest Drosophila Conference (2022). Pre-Conference Workshops: Genotyping with TaqMan and Real-Time PCR Bioinformatics and Genome-Wide Association Studies Summer School: Hands-on training in bioinformatics and drug discovery. Best Paper Presentation: Nigerian Society of Biochemistry and Molecular Biology Conference (2021) Recognized for contributions to Drosophila biomedical research and computational drug design.
๐ Research Focus
Cancer Biology & Genomics: Investigating genetic markers and molecular pathways in cancer progression. Molecular Biology & Bioinformatics: Computational modeling of biomolecules and genome-wide association studies. Drug Discovery & Design: Using in silico techniques to identify potential drug candidates for cancer and neurodegenerative diseases. Precision Medicine & Genetic Profiling: Exploring personalized treatment approaches through pharmacogenomics. Pharmacogenomics & Toxicogenomics: Studying drug responses and toxic effects at the genetic level. Biological Drug Delivery: Developing targeted therapies using nanoformulations and bioactive compounds. Computational Biology: Expertise in homology modeling, molecular docking, virtual screening, and molecular dynamics simulations. Laboratory Techniques: Skilled in gel electrophoresis, ELISA, PCR, spectrophotometry, and tissue imaging.
Publication Top Notes
- Computational Investigation of Polo-like Kinase 1 (PLK1): Inhibitive Potential of Benzimidazole-Carbonamide Derivatives for Cancer Treatment
- Year: 2024
- Authors: Ipinloju, N.; Balogun, T.A.; Ibrahim, A.; Adeyemo, M.A.; Esan, T.O.; Emmanuel, A.V.; Bello, K.A.; Omiyeniyi, G.D.; Oyeneyin, O.E.
- Citation: Physical Chemistry Research
- Link: DOI: 10.22036/pcr.2023.377616.2331
- Identification of Phytochemicals with Inhibitory Potential Against Beta-lactamase Enzymes via Computer-aided Approach
- Year: 2024
- Authors: Nwokebu, G.C.; Adesina, A.B.; Isibor, C.N.; Aigbepue, S.A.; Egbo, C.C.; Pureaziba, N.; Isaac, O.O.; Owolade, A.J.-J.; Alabere, H.O.; Iwuagwu, M.O.
- Citation: Bioorganic Chemistry
- Link: DOI: 10.1016/j.bioorg.2024.107238
- Insight into the Corrosion Inhibiting Potential and Anticancer Activity of 1-(4-methoxyphenyl)-5-methyl-Nโ-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide via Computational Approaches
- Year: 2024
- Authors: Oluwatoba Emmanuel Oyeneyin; Abdulwasiu Ibrahim; Nureni Ipinloju; Adeniyi John Ademoyegun; Nathanael Damilare Ojo
- Citation: Journal of Biomolecular Structure and Dynamics
- Link: DOI: 10.1080/07391102.2023.2260491
- Plant-derived Extracellular Vesicles as Potential Smart Nano Drug Delivery Systems for Antioxidant Vitamins C and E in Alzheimer’s Disease
- Year: 2024
- Authors: Amina Jiyah; Suleiman Alhaji Muhammad; Abdulwasiu Ibrahim; Ibrahim Bulama; Abdullahi Ibrahim; Abdullahi Yahya Abbas; Mustapha Umar Imam; Yusuf Saidu; Lawal Suleiman Bilbis
- Citation: Journal of Drug Delivery Science and Technology
- Link: DOI: 10.1016/j.jddst.2024.105618
- Identification of Potential Acetylcholinesterase (AChE) Inhibitors from Vitis Vinifera: A Case Study of Alzheimerโs Disease (AD)
- Year: 2023
- Authors: Sofela, S.O.; Ibrahim, A.; Bodun, D.S.; Nwankwo, D.O.; Mafimisebi, M.; Abdulrasheed, B.; Balogun, T.; Opeyemi, I.
- Citation: Research Square
- Link: DOI: 10.21203/rs.3.rs-3342491/v1
- Quantum Evaluation and Therapeutic Activity of (E)-N-(4-methoxyphenyl)-2-(4-(3-oxo-3-phenylprop-1-en-1-yl) phenoxy)acetamide and Its Modified Derivatives Against EGFR and VEGFR-2 in the Treatment of Triple-negative Cancer via In Silico Approach
- Year: 2023
- Authors: Ipinloju, N.; Ibrahim, A.; da Costa, R.A.; Adigun, T.B.; Olubode, S.O.; Abayomi, K.J.; Aiyelabegan, A.O.; Esan, T.O.; Muhammad, S.A.; Oyeneyin, O.E.
- Citation: Journal of Molecular Modeling
- Link: DOI: 10.1007/s00894-023-05543-2
- Discovery of Potential Phytochemicals from Carica Papaya Targeting BRCA-1 in Breast Cancer Treatment
- Year: 2023
- Authors: Abdulwasiu Ibrahim; Nureni Ipinloju; Abdulsamad Omotayo Aiyelabegan; Abdulbaki Adio Alfa-Ibrahim; Suleiman Alhaji Muhammad; Oluwatoba Emmanuel Oyeneyin
- Citation: Applied Biochemistry and Biotechnology
- Link: DOI: 10.1007/s12010-023-04473-2
- Discovery of Small Molecule PARKIN Activator from Antipsychotic/Anti-neuropsychiatric Drugs as Therapeutics for PD: An In Silico Repurposing Approach
- Year: 2023
- Authors: Abdulwasiu Ibrahim; Nureni Ipinloju; Nkechi Hope Atasie; Rahmotallah Mosunmola Babalola; Suleiman Alhaji Muhammad; Oluwatoba Emmanuel Oyeneyin
- Citation: Applied Biochemistry and Biotechnology
- Link: DOI: 10.1007/s12010-023-04376-2
- Computational Evaluation of Azadirachta Indica-Derived Bioactive Compounds as Potential Inhibitors of NLRP3 in the Treatment of Alzheimer’s Disease
- Year: 2023
- Authors: Ishabiyi FO; Ogidi J; Olukade BA; Amorha CC; El-Sharkawy LY; Okolo CC; Adeniyi TM; Atasie NH; Ibrahim A.; Balogun TA
- Citation: Journal of Alzheimer’s Disease (JAD)
- Link: DOI: 10.3233/jad-221020
- Discovery of Small Molecule PARKIN Activator as Therapeutics for PD: An In-silico Repurposing Approach
- Year: 2022
- Authors: Abdulwasiu Ibrahim; Nureni Ipinloju; Suleiman Alhaji Muhammad; Oluwatoba Emmanuel Oyeneyin; Nkechi Hope Atasie
- Citation: Preprint
- Link: DOI: 10.21203/rs.3.rs-2035291/v1
- Antioxidant-Rich Nutraceutical as a Therapeutic Strategy for Sickle Cell Disease
- Year: 2022
- Authors: Abdulwasiu Ibrahim
- Citation: Journal of the American Nutrition Association
- Link: DOI: 10.1080/27697061.2022.2108930