MARƍA JOSƉ RUIZ LEAL| Toxicologƭa | Best Researcher Award

Prof. Dr. MARƍA JOSƉ RUIZ LEAL| Toxicologƭa | Best Researcher Award

Prof. Dr at University of Valencia,Ā  Spain

Dr. MarĆ­a JosĆ© Ruiz Leal, born on March 2, 1968, in Spain, is a distinguished Full Professor at the Universitat de ValĆØnciaā€™s Department of Preventive Medicine and Public Health. With a career spanning over two decades, she has significantly contributed to toxicology and food science, specializing in in vitro and in vivo studies related to pesticides and mycotoxins. Dr. Ruiz Leal has been part of multiple academic roles, growing from Associate Professor to Full Professor since 2018. She coordinates the Masterā€™s program in Food Quality and Safety at UV and leads the RiskTox research group. A European Registered Toxicologist since 2018, she is recognized for her extensive research portfolio and mentorship, supervising numerous doctoral theses and authoring over 130 scientific publications.

Profile

Orcid

Education šŸŽ“

Dr. MarĆ­a JosĆ© Ruiz Lealā€™s educational journey began at the Universitat de ValĆØncia (UV), where she earned her First Degree in Pharmacy in 1992, laying the foundation for her future in academic and applied toxicology. In 1997, she completed her PhD in Pharmacy, obtaining European certification, which equipped her with expertise in pharmaceutical sciences and toxicological research. Her education laid the groundwork for her focus on public health and safety, integrating in-depth studies on food sciences and toxicology. With continuous professional development, Dr. Ruiz Leal gained credentials as a European Registered Toxicologist (ERT) in 2018, underscoring her commitment to advancing toxicological standards and education.

Experience šŸ§‘ā€šŸ«

Dr. MarĆ­a JosĆ© Ruiz Lealā€™s extensive career at the Universitat de ValĆØncia (UV) commenced in 1998 with teaching and research roles, evolving from Assistant to Full Professor by 2018. Her work includes academic coordination of the Masterā€™s in Food Quality and Safety program since 2023. She has directed numerous research initiatives, leading eight significant projects and collaborating in about 20 regional, national, and international studies. Her focus lies in evaluating chemical impacts through in vitro cell cultures and in vivo methods, contributing to over 200 scientific congresses and publishing 131 papers in peer-reviewed journals, 90 of which are in Q1. Her experience is complemented by supervising 12 high-quality doctoral theses.

šŸ† Awards and Honors

Dr. MarĆ­a JosĆ© Ruiz Lealā€™s dedication and excellence in her field have been marked by numerous accolades. She boasts four sexenios of recognized research quality, the most recent in 2021, highlighting her sustained contributions to scientific production. Her doctoral theses supervision has been distinguished with quality mentions in the Food Science program. Her extensive publication record, with 131 articles and a significant h-index of 46, showcases the impact of her work, bolstered by 5,494 citations. As a European Registered Toxicologist since 2018, Dr. Ruiz Leal’s contributions to toxicology have been acknowledged within the scientific community and by her peers.

šŸ”¬ Research Focus

Dr. MarĆ­a JosĆ© Ruiz Lealā€™s research is rooted in toxicology and food safety, focusing on the impact of pesticides and mycotoxins using both in vitro and in vivo methodologies. Her work explores the cellular and systemic effects of contaminants, utilizing advanced cell culture techniques to assess toxicity and safety in food products. As the director of the RiskTox research group at UV, she leads innovative projects investigating chemical exposures and public health risks. Her contributions span international collaborations, addressing challenges in toxicological research and advancing knowledge in food science. Her expertise supports the development of safer food practices and regulatory standards.

Conclusion

Dr. Marƭa JosƩ Ruiz Leal is an exemplary researcher who has demonstrated exceptional academic and scientific leadership over her distinguished career. Her extensive publication record, contributions to pioneering toxicological research, and leadership within scientific organizations make her highly deserving of the Best Researcher Award. Moving forward, expanding into new, emerging research areas and increasing her public engagement would further elevate her impact in the field.

Publications šŸ“š

  • “Integrated Approach to Cyclopiazonic Acid Cytotoxicity Using In Vitro (2D and 3D Models) and In Silico Methods”
    • Authors: C. MartĆ­nez-Alonso, L. Izzo, Y. RodrĆ­guez-Carrasco, MJ. Ruiz
    • Year: 2024
    • Journal: Toxins 16, 473
    • Citations: 3

 

  • “Amitraz mechanisms of cytotoxicity in a characterized SH-SY5Y cells spheroid model”
    • Authors: F. Franco-Campos, M. FernĆ”ndez-FranzĆ³n, Y. RodrĆ­guez-Carrasco, MJ. Ruiz
    • Year: 2024
    • Journal: Toxicology 509, 153987
    • DOI: Link

 

  • “Identification of Biotransformation Products of T-2 Toxin in HepG2 Cells Using LC-Q-TOF MS”
    • Authors: M. Taroncher, V. Zingales, Y. RodrĆ­guez-Carrasco, MJ. Ruiz
    • Year: 2024
    • Journal: Foods 13 (10), 1501
    • DOI: Link

 

  • “Effect of Spirulina and Fish Processing By-Products Extracts on Citrinin-Induced Cytotoxicity in SH-SY5Y Cells”
    • Authors: FJ. MartĆ­-Quijal, JM. Castagnini, FJ. Barba, MJ. Ruiz
    • Year: 2024
    • Journal: Foods 13 (12), 1932
    • DOI: Link

 

  • “Comparative Study of Spheroids (3D) and Monolayer Cultures (2D) for the In Vitro Assessment of Cytotoxicity Induced by the Mycotoxins Sterigmatocystin, Ochratoxin A and Patulin”
    • Authors: V. Zingales, MR. Esposito, M. Quagliata, E. Cimetta, MJ. Ruiz
    • Year: 2024
    • Journal: Foods 13 (4), 564
    • DOI: Link

 

  • “Chlorpyrifos induces cytotoxicity via oxidative stress and mitochondrial dysfunction in HepG2 cells”
    • Authors: C. MontanarĆ­, F. Franco-Campos, M. Taroncher, Y. RodrĆ­guez-Carrasco, V. Zingales, MJ. Ruiz
    • Year: 2024
    • Journal: Food Chemistry and Toxicology 192, 114933
    • DOI: Link

 

  • “Using Microfluidic Hepatic Spheroid Cultures to Assess Liver Toxicity of T-2 Mycotoxin”
    • Authors: M. Taroncher, AM. Gonzalez-Suarez, K. Gwon, S. Romero, AD. Reyes-Figueroa, Y. RodrĆ­guez-Carrasco, MJ. Ruiz, G. Stybayeva, A. Revzin, JM. de Hoyos-Vega
    • Year: 2024
    • Journal: Cells

 

 

Monika Kopeć | medical chemistry | Young Scientist Award

Dr. Monika Kopeć | medical chemistry | Young Scientist Award

šŸ‘Øā€šŸ«Profile Summary

In 2018, I earned a doctorate in chemical science from the Faculty of Chemistry at Lodz University of Technology, specializing in the study of biological systems using spectroscopic techniques. Additionally, I completed a master’s program in logistics with a focus on supply chain management. With nine years of experience in chemistry, including managing research projects, I have honed my skills in team collaboration and project management. I have also undertaken various courses and workshops to enhance my expertise, including those in self-motivation, effective learning, and commercializing research. Now, I aim to further expand my knowledge and skills in research techniques and seek opportunities in leading chemical or logistics companies.

šŸŒ Professional Profiles

Educational Qualifications šŸ“š

Postgraduate Studies in Data Analysis and Data Mining University of Lodz, Faculty of Mathematics and Computer Science October 2021 – June 2022 PhD Studies in Chemistry Lodz University of Technology, Faculty of Chemistry October 2013 – September 2018 Dissertation awarded by the Council of the Chemical Faculty of Lodz University of Technology Postgraduate Studies in Forensic Biology University of Lodz, Faculty of Biology October 2014 – March 2016 Masters Studies in Logistics with Major in Supply Chain Management University of Lodz, Faculty of Management October 2012 – July 2014 Masters Studies in Chemistry with Major in Medical Chemistry Lodz University of Technology, Faculty of Chemistry March 2012 – July 2013 Engineering Studies in Chemistry with Major in Chemical Analysis in Environmental Control and Quality Engineering Lodz University of Technology, Faculty of Chemistry October 2008 – January 2012 Biologically-Chemical Profile High Comprehensive School S. Å»eromskiego in OzorkĆ³w September 2005 – June 2008

Work Experience šŸ’¼

Lecturer Lodz University of Technology October 2019 – Present Responsibilities include experimental analysis, conducting classes, and research documentation. Postdoctoral Fellowship Jagiellonian University in Krakow January 2023 – February 2023 Engineering and Technical Specialist Lodz University of Technology May 2019 – December 2021 Duties involved equipment preparation, chemical reagent management, and ordering. Assistant Lodz University of Technology October 2018 – October 2019 Conducted experimental analysis, classes, and research documentation. Chemist Lodz University of Technology October 2015 – November 2018 Prepared reagents, conducted spectroscopy measurements, and provided technical support. PhD Student Lodz University of Technology October 2013 – September 2018 Conducted measurements using spectroscopy techniques. Apprenticeships Institute of Polymer and Dye Engineering in Zgierz District Police Headquarters in Zgierz July 2011 – August 2011 / July 2010 – August 2010 Hostess Cursor S.A. Sales & Marketing Services August 2009 – September 2009 Trainee District Police Headquarters in Zgierz June 2008 – September 2008

Trainings and Workshops šŸŽ“

AFM Modes Training: Contact, tapping, ScanAsyst, Resonance Enhanced AFM-IR, Tapping AFM-IR, and Micro View Dates: 05.12.2022 – 09.12.2022 Laboratory Procedures Training: Operation and proper use of equipment such as the CO2 incubator Memmert ICO150med, laboratory centrifuge MPW 260R with cooling, and laminar chamber II safety class ESCO AIRSTREAM type AC2-4EB Dates: 4.10.2022 – 6.10.2022 Techniques Training: SDS-PAGE, Western Blot, and visualization of protein gels using Comassie and Stain-Free methods Usage of the Mini-Protean Tetra Cell, Trans-Blot Turbo, and ChemiDoc MP systems Dates: 4.10.2022 – 6.10.2022 Microscope and Imaging Software Training: Use of the Leica DMiL LED inverted microscope, Leica FLEXACAM C1 camera, and Leica LAS X software Quick Reading and Effective Learning Methods Course Commercialization of Research and Establishing Cooperation with Industry Workshop Team Coaching Workshop: Motivating Members to Achieve Common Goals Zetasizer and Nanosight Analyzers Training for Particle Size Measurements Training on the Use of Nanomaterials in Nanomedicine and Bionanotechnology Self-Motivation and Team Motivation Workshop

Projects šŸš€

Raman Imaging of Human Cancerous Tissue and Cell Cultures (2016) Function: Project Manager Identification of Tumor Changes Based on Imaging and Raman Spectroscopy (2019) Function: Project Contractor Raman Imaging and Endospectroscopy in Oncological Omic Studies (2020 – 2022) Function: Project Contractor Analysis of Angiogenesis Process in Human Breast Tissue Using Raman Spectroscopy (2020 – 2021) Function: Project Manager Influence of Sugars on Metabolism of Lung Cancer Cells (2022) Function: Project Manager The Triangle: Carotenoids-Retinoids-Cytochromes in Cancer Progression (2022 – Present) Function: Project Contractor

Awards šŸ†

  • Various Scholarships and Rector’s Scholarships during PhD Studies (2014 – 2018)
  • Platinum Medal at International Warsaw Invention Show (2019)
  • Award of the Rector of the Medical University of Lodz (2019)
  • Award for Scientific Achievements in Spectroscopic Identification of Cancer Changes (2019)
  • Award Supporting Scientific Excellence under the “Initiative of Excellence – Research University” Program (2020, 2021)

šŸ“šTop Noted Publication

  1. Title: Revision of Commonly Accepted Warburg Mechanism of Cancer Development: Redox-Sensitive Mitochondrial Cytochromes in Breast and Brain Cancers by Raman Imaging
    • Authors: H. Abramczyk, J. Surmacki, B. Brozek-Pluska, M. Kopec
    • Journal: Cancers
    • DOI: 10.3390/cancers13112599
    • Publication Date: Unknown

 

  1. Title: Raman imaging and statistical methods for analysis various type of human brain tumors and breast cancers
    • Authors: M. Kopec, J. Surmacki, M. Błaszczyk, M. Radek, H. Abramczyk
    • Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
    • DOI: 10.1016/j.saa.2021.120091
    • Publication Date: 2021

 

  1. Title: The role of pro- and antiangiogenic factors in angiogenesis process by Raman spectroscopy
    • Authors: M. Kopec, H. Abramczyk
    • Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
    • DOI: 10.1016/j.saa.2021.120667
    • Publication Date: 2021

 

  1. Title: Double face of cytochrome c in cancers by Raman imaging
    • Authors: H. Abramczyk, B. Brożek-Płuska, M. Kopeć
    • Journal: Scientific Reports
    • DOI: Link
    • Publication Date: 2022

 

  1. Title: Analysis of eggs depending on the hens’ breeding systems by Raman spectroscopy

 

  1. Title: Decoding Breast Cancer Metabolism: Hunting BRCA Mutations by Raman Spectroscopy
    • Authors: M. Kopec, B. Romanowska-Pietrasiak, H. Abramczyk
    • Journal: Photochem
    • DOI: 10.3390/photochem2030048
    • Publication Date: 2022

 

  1. Title: Hyperglycemia and cancer in human lung carcinoma by means of Raman spectroscopy and imaging
    • Authors: M. Kopec, K. Beton, K. Jarczewska, H. Abramczyk
    • Journal: Scientific Reports
    • DOI: 10.1038/s41598-022-21483-y
    • Publication Date: 2022

 

  1. Title: Hemoglobin and cytochrome c. reinterpreting the origins of oxygenation and oxidation in erythrocytes and in vivo cancer lung cells
    • Authors: H. Abramczyk, J.M. Surmacki, M. Kopeć, K. Jarczewska, B. Romanowska-Pietrasiak
    • Journal: Scientific Reports
    • DOI: 10.1038/s41598-023-41858-z
    • Publication Date: 2023

 

  1. Title: Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming

 

  1. Title: The role of glucose and fructose on lipid droplet metabolism in human normal bronchial and cancer lung cells by Raman spectroscopy