Kyu Sik Kim| Medicine | Young Scientist Award

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Mr. Kyu Sik Kim| Medicine | Young Scientist Award

Mr at Seoul National University, South Korea

Kyu Sik Kim is a dedicated PhD candidate at Seoul National University, specializing in systems neuroscience. His research focuses on how the hypothalamus regulates feeding behavior and seeks to bridge the gap between animal and human studies. Passionate about improving therapeutic outcomes, he aims to translate his findings into better treatment options.

 

Publication profile

Scopus

Orcid

Scholar

šŸŽ“ Education & Training

M.S./Ph.D. Candidate in Biomedical Science, Seoul National University, College of Medicine (2020ā€“Present) Advisor: Prof. Hyung Jin Choi. B.S. in Life Science, Sogang University, Seoul, Korea (2014-2018)

šŸ”¬ Major Research Interests

Brain activity and ethology analysis with artificial intelligence. Internal state changes in the brain. Competing needs and motivation in the brain. Hypothalamic neuronal circuits in emotion and eating. Translational research and clinical applications

šŸ† Honors, Funding & Awards

2024: 2-year research program (48M Won) for cultivating future generations in science and engineering. 2024: Basic Academic Field Academic Subsequent Generation (24M Won). 2024: Optodbs Travel Grant. Multiple prizes for Outstanding Graduate Student at Seoul National University (2023-2024). Best Paper Award (March-May 2023)

šŸ›  Skills & Professional Expertise

Software Tools: Ethovision, Inscopix Data Processing, MATLAB, Python. Experimental Techniques: Immunocytochemistry, stereotaxic surgery, animal behavior experiments, and fMRI imaging. Teaching & Mentoring: Guided students in medical research programs at Seoul National University

Publication

  • Lateral Hypothalamic Leptin Receptor Neurons Drive Hunger-Gated Food-Seeking and Consummatory Behaviours in Male Mice
    • Authors: Y.H. Lee, Y.B. Kim, K.S. Kim, M. Jang, H.Y. Song, S.H. Jung, D.S. Ha, J.S. Park, …
    • Published In: Nature Communications, 14(1), 1486
    • Citations: 19
    • Year: 2023

 

  • GLP-1 Increases Preingestive Satiation via Hypothalamic Circuits in Mice and Humans
    • Authors: K.S. Kim, J.S. Park, E. Hwang, M.J. Park, H.Y. Shin, Y.H. Lee, K.M. Kim, L. Gautron, …
    • Published In: Science, 385(6707), 438-446
    • Citations: 6
    • Year: 2024

 

  • Acoustic Deep Brain Modulation: Enhancing Neuronal Activation and Neurogenesis
    • Authors: H. Ham, K.S. Kim, J.H. Lee, D.N. Kim, H.J. Choi, J.J. Yoh
    • Published In: Brain Stimulation
    • Year: 2024

 

  • A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
    • Authors: K.S. Kim, Y.H. Lee, Y.B. Kim, J.W. Yun, H.Y. Song, J.S. Park, S.H. Jung, J.W. Sohn, …
    • Published In: bioRxiv
    • Year: 2023

 

N T Pramathesh Mishra | Pharmacology | Young Scientist Award

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Assoc Prof Dr. N T Pramathesh Mishra | Pharmacology| Best Scholar Award

Associate Professor at Hygia College of Pharmacy, India

As an accomplished Associate Professor in Pharmacology, I aim to contribute to innovative scientific research, advanced drug discovery, and training future healthcare professionals . With over a decade of experience and recognition, including awards like the Daniel Bovet Distinguished Young Scientist Award and Karma Veer Chakra Global Youth Fellowship , I am dedicated to advancing pharmacology and fostering collaborative research initiatives . My goal is to engage in cutting-edge research, impactful workshops, and inspire the next generation of scientists and healthcare providers

Publication

    1. Effect of COVID-19 Pandemic Lockdowns on Planned Cancer Surgery for 15 Tumour Types in 61 Countries
      Journal: The Lancet Oncology
      Year: 2021
      Citations: 256

     

    1. Global Impacts of Pre-and Post-COVID-19 Pandemic: Focus on Socio-Economic Consequences
      Journal: Sensors International
      Year: 2020
      Citations: 140

     

    1. Endophyte-Mediated Modulation of Defense-Related Genes and Systemic Resistance in Withania somnifera (L.) Dunal Under Alternaria alternata Stress
      Journal: Applied and Environmental Microbiology
      Year: 2018
      Citations: 77

     

    1. Molecular Mechanisms and Therapeutic Strategies for Levodopa-Induced Dyskinesia in Parkinsonā€™s Disease
      Journal: Frontiers in Pharmacology
      Year: 2022
      Citations: 30

     

    1. Supplementation of Trichoderma Improves the Alteration of Nutrient Allocation and Transporter Genes Expression in Rice Under Nutrient Deficiencies
      Journal: Plant Physiology and Biochemistry
      Year: 2019
      Citations: 23

     

    1. Clinicomycological Study of Dermatophytoses in Children Presenting at a Tertiary Care Center
      Journal: Indian Journal of Paediatric Dermatology
      Year: 2018
      Citations: 21

    Conclusion

    N T Pramathesh Mishra is a strong candidate for the Young Scientist Award due to his robust academic background, impactful research contributions, and recognition through prestigious awards. His diverse experience, innovative patents, and involvement in significant research projects reflect his potential as a leading young scientist. Addressing the areas for improvement, particularly in publication and broader collaboration, could further strengthen his candidacy and enhance his impact in the scientific community.

Daniele Florio | Pharmaceutical science | Young Scientist Award

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Mr. Daniele Florio | Pharmaceutical science | Young Scientist Award

Daniele Florio is a dedicated researcher in pharmaceutical sciences, currently pursuing a Ph.D. at the University of Naples Federico II. His doctoral work focuses on integrated molecular approaches targeting mutated Nucleophosmin 1 in Acute Myeloid Leukemia, scheduled for completion in October 2024. Daniele brings extensive experience from his Marie Sklodowska-Curie secondment and voluntary internship, specializing in peptide synthesis, mass spectrometry, and spectroscopic techniques. With a strong publication record and active participation in international conferences, he contributes significantly to the fields of amyloid aggregation, chemical catalysis, and drug development, showcasing advanced skills in scientific research and analysis.

Profile

Scopus

šŸ‘Øā€šŸ«Professional Experience

Tutoring Activities (Grant Type B) 2023-2024, Naples, Italy, Department of Pharmacy, University of Naples Federico II, Provided supplementary teaching for Chemistry and Inorganic Chemistry courses for Pharmacy and CTF degree students. Ph.D. Candidate in Pharmaceutical Sciences (XXXVII Cycle) 2021 ā€“ Present, Naples, Italy, Department of Pharmacy, University of Naples Federico II, PhD Project: Integrated molecular approaches targeting mutated Nucleophosmin 1 in Acute Myeloid Leukemia., Scheduled PhD end: October 31, 2024. Secondee under Marie Skłodowska-Curie Research and Innovation Staff Exchange Action June 2022 ā€“ March 2023, Dublin, Ireland, Keladapharmachem, Participated in the GreenX4Drug (EU funded H2020 RISE project), focusing on developing novel asymmetric chemical catalysts for manufacturing high-value APIs and advanced intermediates.. Voluntary Internship Post-Degree 2018 ā€“ 2019, Naples, Italy, Department of Pharmacy, University of Naples Federico II, Designed, synthesized, and characterized peptides, peptidomimetics, and small molecules using solid-phase and solution methodologies. Utilized mass spectrometry (ESI) for identifying synthetic compounds and applied analytical and preparative methodologies (HPLC) for their purification and characterization. Conducted structural and functional characterization of biomolecules through spectroscopic techniques (CD, Fluorescence, SPR, UV-Vis). Supervisor: Prof. Daniela Marasco

šŸŽ“Education and Training

Biologist Board Examination February 7, 2022, University of Naples Federico II, Naples, Italy Masterā€™s Degree in Biological Science (Molecular Diagnostics Field) July 12, 2021, Naples, Italy Department of Pharmacy, University of Naples Federico II Experimental Thesis: “Protein fragments of Nucleophosmin 1 as models of amyloids”, Supervisor: Prof. Antonello Merlino, Co-Supervisor: Prof. Daniela Marasco,k Grade: 110/110. Bachelorā€™s Degree in Biological Science (Molecular Diagnostics Field) March 15, 2018, Naples, Italy Department of Pharmacy, University of Naples Federico II Experimental Thesis: “Amyloid-like aggregation of Nucleophosmin 1 regions related to Acute Myeloid Leukemia: spectroscopic studies” Supervisor: Prof. Daniela Marasco Grade: 106/110

šŸ“–Certifications

English TELSA C1, Grade B Language Certification ESAT, Malta Further & Higher Education Authority

Skills and Competencies

Organizational Skills

  • Efficient under pressure.
  • Adaptive to changes and new situations.
  • Strong independent work organization and goal achievement.

Job-related Skills

  • Solid-phase peptide synthesis and combinatorial peptide libraries using Fmoc/Boc chemistry.
  • Experience with various peptide synthesizers (BIOTAGE, Liberty Blue 2.0).
  • Proficient in analysis and purification using ESI mass spectrometry, HPLC, and flash purification systems.
  • Skilled in spectroscopic techniques (CD, Fluorescence, DLS, SPR, UV-Vis, FTIR, NMR).

Digital Skills

  • Proficient in Microsoft Office Suite.
  • Experienced with operating systems: MS-Windows, MacOS, LINUX.
  • Proficient in scientific data analysis software (GraphPad Prism).
  • Knowledgeable in databases (PubMed) and bibliographic management software (EndNote, Mendeley).
  • Proficient with video conferencing software (Teams, Skype, Zoom, Google Meet).
  • Excellent knowledge of major browsers (Edge, Chrome, Firefox, Safari, Opera).

šŸŒProjects

National Project Participation

  • BANDO-PRIN-2022. Research Project: Design, synthesis, and investigation of novel G-quadruplex aptamers against STAT3 and the interleukin-6 receptor (G4-APTASTAT).
  • Project Coordinator and Head of Research Unit: Prof. GALEONE Aldo

Bibliometric Parameters

  • H-index from Scopus: 11
  • Number of Publications: 24
  • Citations: 388

 

Publications Top Notes šŸ“

  • The effects of histidine substitution of aromatic residues on the amyloidogenic properties of the fragment 264ā€“277 of nucleophosmin 1
    • Authors: D. Florio, P. Luciano, C. Di Natale, D. Marasco
    • Journal: Bioorganic Chemistry
    • Volume: 147
    • Year: 2024
    • Pages: 107404

 

  • Could Targeting NPM1c+ Misfolding Be a Promising Strategy for Combating Acute Myeloid Leukemia?
    • Authors: D. Florio, D. Marasco
    • Journal: International Journal of Molecular Sciences
    • Volume: 25
    • Issue: 2
    • Year: 2024
    • Pages: 811

 

  • Modulation of hydrogel networks by metal ions
    • Authors: S. La Manna, D. Florio, C. Di Natale, D. Marasco
    • Journal: Journal of Peptide Science
    • Volume: 29
    • Issue: 8
    • Year: 2023
    • Article ID: e3474

 

  • Ruthenium complexes bearing glucosyl ligands are able to inhibit the amyloid aggregation of short histidine-peptides
    • Authors: D. Florio, S. La Manna, A. Annunziata, M. Monti, D. Marasco
    • Journal: Dalton Transactions
    • Volume: 52
    • Issue: 25
    • Year: 2023
    • Pages: 8549ā€“8557

 

  • Insights into Network of Hot Spots of Aggregation in Nucleophosmin 1
    • Authors: D. Florio, S. La Manna, C. Di Natale, A.M. Malfitano, D. Marasco
    • Journal: International Journal of Molecular Sciences
    • Volume: 23
    • Issue: 23
    • Year: 2022
    • Pages: 14704

 

  • Hydrogelation tunability of bioinspired short peptides
    • Authors: S. La Manna, D. Florio, V. Panzetta, C. Di Natale, D. Marasco
    • Journal: Soft Matter
    • Volume: 8
    • Year: 2022
    • Pages: 8

 

Antonios Kousaxidis | Medicinal Chemistry | Best Researcher Award

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Ā Mr. Antonios Kousaxidis | Medicinal Chemistry |Best Researcher Award

Ā Mr at School of Pharmacy, Aristotle University of Thessaloniki, Greece

A seasoned educator and researcher with extensive experience in physics, holding positions from Assistant to Associate Professor at IAU, Urmia, and Urmia University of Technology. Specialized in teaching a range of undergraduate to Ph.D. courses including Quantum Mechanics, Laser Physics, and Nonlinear Dynamical Systems. Proficient in Maple and Matlab programming with a strong background in finite element method analysis. Led impactful research projects in chaotic systems, cancer treatment, and national security, earning multiple awards including the Kharazmi Scientific Festival Second Prize. A recognized leader in academia with a commitment to advancing scientific knowledge and education.

Profile

  1. Scopus

šŸŽ“ Education:

Masterā€™s Degree in Medicinal Chemistry: (9.85/10) from Departments of Chemistry, Medicine, Biological Applications and Technology, University of Ioannina, 45110, Ioannina, Greece.Ā Bachelor’s Degree in Chemistry: (7.76/10) from Department of Chemistry, School of Sciences, University of Ioannina, 45110, Ioannina, Greece.

Personal Skills:

Synthetic Organic Chemistry and Biochemistry: Training in synthetic organic chemistry and biochemistry applied to drug design, with experience in several areas of synthetic methodology using retrosynthetic approaches. Metal-Based Coupling Reactions: Excellent knowledge and practice of metal-based coupling reactions in modern organic chemistry. Synthetic Routes Optimization: Training in synthetic routes optimization using one-pot reactions during masterā€™s thesis. Analytical Methods: Proficient in NMR, IR, UV, and mass spectrometry for identifying organic compounds. Small Molecule Synthesis: Synthesis of small molecule organic compounds and isolation by recrystallization. Purification and Separation: Excellent knowledge and practice in chromatographic methods like column, preparative, and thin-layer chromatography for purifying and separating organic compounds. Biochemical Protocols: Good practice in using biochemical protocols for enzyme kinetics experiments. Drug Discovery Programs: Extensive experience in drug discovery programs, structure-based drug design, molecular docking, and SAR estimation models using in silico methods (Discovery Studio, Chimera, LigandScout, PyMOL, OpenBabel, ADMET). Scientific Manuscripts: Proficient in writing and preparing scientific manuscripts.

šŸ’» Software Skills:

Office Suite (ECDL degree) – Word processing, spreadsheets, presentations, etc. Calculative and predictive programs like MestReNova, Topspin DataAnalysis, ChemDraw Ultra, MedChem Designer, and BioLoom.

Research Focus:

A. Kousaxidis primarily focuses on the design and synthesis of novel compounds with therapeutic potential, particularly targeting enzymes such as aldose reductase (ALR2) and protein tyrosine phosphatase 1B (PTP1B). The research also encompasses antimicrobial agents, lipoxygenase inhibitors, and therapeutic strategies for conditions like diabetes mellitus and sepsis.

Publications Top Notes šŸ“

  • A Molecular Hybridization Approach for the Design of Selective Aldose Reductase (ALR2) Inhibitors and Exploration of Their Activities Against Protein Tyrosine Phosphatase 1B (PTP1B)
    • Authors: Kousaxidis, A., Petrou, A., Rouvim, P., Nicolaou, I., Geronikaki, A.
    • Journal: Journal of Molecular Structure
    • Year: 2023
    • Volume: 1271
    • Article Number: 134116
    • Citations: 3
    • Summary: This study presents a hybridization approach to develop selective ALR2 inhibitors and investigates their potential activities against PTP1B, highlighting their dual therapeutic potential.

 

  • Design, Synthesis, and Pharmacological Evaluation of Indazole Carboxamides of N-Substituted Pyrrole Derivatives as Soybean Lipoxygenase Inhibitors
    • Authors: Lavrentaki, V., Kousaxidis, A., Theodosis-Nobelos, P., Koutsopoulos, K., Nicolaou, I.
    • Journal: Molecular Diversity
    • Year: 2023
    • Citations: 2
    • Summary: This paper discusses the synthesis and evaluation of novel indazole carboxamides, demonstrating significant inhibitory activity against soybean lipoxygenase.

 

  • N-Derivatives of (Z)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1H-indole-2-carboxylates as Antimicrobial Agentsā€”In Silico and In Vitro Evaluation
    • Authors: Petrou, A., Geronikaki, A., Kartsev, V., Nicolaou, I., Vizirianakis, I.S.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Issue: 1
    • Article Number: 131
    • Citations: 4
    • Summary: This open-access article evaluates the antimicrobial activity of new N-derivatives, supported by both in silico and in vitro methods.

 

  • Non-acidic Bifunctional Benzothiazole-Based Thiazolidinones with Antimicrobial and Aldose Reductase Inhibitory Activity as a Promising Therapeutic Strategy for Sepsis
    • Authors: Kousaxidis, A., Kovacikova, L., Nicolaou, I., Stefek, M., Geronikaki, A.
    • Journal: Medicinal Chemistry Research
    • Year: 2021
    • Volume: 30
    • Issue: 10
    • Pages: 1837-1848
    • Citations: 13
    • Summary: This research explores benzothiazole-based thiazolidinones with dual activity, suggesting a promising approach for treating sepsis.

 

  • Aldose Reductase and Protein Tyrosine Phosphatase 1B Inhibitors as a Promising Therapeutic Approach for Diabetes Mellitus
    • Authors: Kousaxidis, A., Petrou, A., Lavrentaki, V., Nicolaou, I., Geronikaki, A.
    • Journal: European Journal of Medicinal Chemistry
    • Year: 2020
    • Volume: 207
    • Article Number: 112742
    • Citations: 39
    • Summary: This review highlights the potential of targeting ALR2 and PTP1B as a therapeutic strategy for diabetes, emphasizing recent advances and future perspectives.

 

Pallab Mandal | Jadavpur University.

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Pallab Mandal :Leading Researcher in Jadavpur University.

šŸ‘Øā€šŸ« Pallab Mandal , an Mr at Jadavpur University. stands as a distinguished academic and researcher in the Ā Management and Accounting. Holding PhD Scholar: Pursuing from Jadavpur University Master of Pharmacy: Jadavpur University (2019), India. šŸŒŸPallab Mandal is a dedicated professional with extensive experience in bio-analytical method development, scientific/medical writing, and profound expertise in breast cancer research. His journey showcases a robust background in pharmaceuticals, with a strong focus on bioequivalence studies, LC-MS/MS analysis, and pharmacokinetic investigations. He possesses a comprehensive skill set in analytical techniques, GLP compliance, and a track record of successful publications and awards in the pharmaceutical domain.

šŸŒ Professional Profiles:

šŸŽ“ Academic Background

PhD Scholar: Pursuing from Jadavpur University Master of Pharmacy: Jadavpur University (2019) ,Bachelor of Pharmacy: Jadavpur University (2015) ,Diploma in Pharmacy: Institute of Pharmacy, Kalyani (2009) Various other diplomas and certifications in related medical fields

šŸ¢ Work Experience

BioAnalyst LC-MS/MS and Head of Quality Assurance: Taab BioStudy Services, Jadavpur (July 2023 – Present)Senior BioAnalyst LC-MS/MS (Lab Incharge): Taab BioStudy Services, Jadavpur (Aug 2015 – July 2023)Teaching experience at Bio-equivalence study center, Jadavpur University (2018 – Present) Pharmacist roles in renowned healthcare facilities.

šŸ… Achievements

National Award: M.N. DEV Memorial Award for outstanding performance in D.Pharm final exam International Scientist Award: Recognized as the Best Researcher at INSO Award for Engineering, Science, and Medicine Various awards and accolades for published research papers

šŸ”¬ Research & Publications

Diverse research projects focused on bioanalytical method development, pharmacokinetic studies, and drug analysis in human plasma Author of numerous research papers in esteemed national and international journals

šŸ“š Skills & Competencies

Proficient in analytical method development for drug determination in tablets and plasma using HPLC, LC-MS/MS, and various analytical software Expertise in GLP maintenance, validation of developed methods, and analysis of pharmacokinetic data Industrial exposures, workshops, and training in pharmaceutical analysis

Top Noted Publication:

Simultaneous determination and quantitation of diosmetin and hesperetin in human plasma by liquid chromatographic mass spectrometry with an application to pharmacokinetic studies Published on 2019/5/1 Cited by 12

A critical insight of modern herbal drugs therapy under the purview of toxicity and authenticity Published on 2018 Cited by 12

Determination and quantitation of benzofuran, Indole and piperazine containing selective serotonin reuptake inhibitor vilazodone hydrochloride in human plasma by LC-ESI-MS/MS ā€¦ Published on 2021 Cited by 7

LC-MS/MS method development and validation of an antihistaminic, calcium channel blocker, di-phenyl-methyl-piperazine group containing cinnarizine in human plasma with an ā€¦Published on 2018 cited by 5

Repeated dose toxicity study in rats of the formulation containing metformin and sitagliptin using microwave assisted acrylamide grafted cassia tora as polymer Published on 2016/6/1 Cited by 4

Analytical method development and validation of trimethylazanium containing anti-leishmanial phospholipid drug miltefosine by liquid chromatography quadruple tandem mass ā€¦ Published on2016/6/1 Cited by 4

Microwave Assisted Acrylamide Grafting on a Natural Gum Cassia Tora: Characterization and Pharmacokinetic Evaluation of the Formulation Containing Metformin and Sitagliptin in ā€¦Published on 2022 Cited by 1

Anti-Hypertensive Activity of Some Selected Unani Formulations: An Evidence-Based Approach for Verification of Traditional Unani Claims Using LC-MS/MS for the Evaluation of ā€¦ Published on 2022/8/8