Kyu Sik Kim| Medicine | Young Scientist Award

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Mr. Kyu Sik Kim| Medicine | Young Scientist Award

Mr at Seoul National University, South Korea

Kyu Sik Kim is a dedicated PhD candidate at Seoul National University, specializing in systems neuroscience. His research focuses on how the hypothalamus regulates feeding behavior and seeks to bridge the gap between animal and human studies. Passionate about improving therapeutic outcomes, he aims to translate his findings into better treatment options.

 

Publication profile

Scopus

Orcid

Scholar

šŸŽ“ Education & Training

M.S./Ph.D. Candidate in Biomedical Science, Seoul National University, College of Medicine (2020ā€“Present) Advisor: Prof. Hyung Jin Choi. B.S. in Life Science, Sogang University, Seoul, Korea (2014-2018)

šŸ”¬ Major Research Interests

Brain activity and ethology analysis with artificial intelligence. Internal state changes in the brain. Competing needs and motivation in the brain. Hypothalamic neuronal circuits in emotion and eating. Translational research and clinical applications

šŸ† Honors, Funding & Awards

2024: 2-year research program (48M Won) for cultivating future generations in science and engineering. 2024: Basic Academic Field Academic Subsequent Generation (24M Won). 2024: Optodbs Travel Grant. Multiple prizes for Outstanding Graduate Student at Seoul National University (2023-2024). Best Paper Award (March-May 2023)

šŸ›  Skills & Professional Expertise

Software Tools: Ethovision, Inscopix Data Processing, MATLAB, Python. Experimental Techniques: Immunocytochemistry, stereotaxic surgery, animal behavior experiments, and fMRI imaging. Teaching & Mentoring: Guided students in medical research programs at Seoul National University

Publication

  • Lateral Hypothalamic Leptin Receptor Neurons Drive Hunger-Gated Food-Seeking and Consummatory Behaviours in Male Mice
    • Authors: Y.H. Lee, Y.B. Kim, K.S. Kim, M. Jang, H.Y. Song, S.H. Jung, D.S. Ha, J.S. Park, …
    • Published In: Nature Communications, 14(1), 1486
    • Citations: 19
    • Year: 2023

 

  • GLP-1 Increases Preingestive Satiation via Hypothalamic Circuits in Mice and Humans
    • Authors: K.S. Kim, J.S. Park, E. Hwang, M.J. Park, H.Y. Shin, Y.H. Lee, K.M. Kim, L. Gautron, …
    • Published In: Science, 385(6707), 438-446
    • Citations: 6
    • Year: 2024

 

  • Acoustic Deep Brain Modulation: Enhancing Neuronal Activation and Neurogenesis
    • Authors: H. Ham, K.S. Kim, J.H. Lee, D.N. Kim, H.J. Choi, J.J. Yoh
    • Published In: Brain Stimulation
    • Year: 2024

 

  • A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
    • Authors: K.S. Kim, Y.H. Lee, Y.B. Kim, J.W. Yun, H.Y. Song, J.S. Park, S.H. Jung, J.W. Sohn, …
    • Published In: bioRxiv
    • Year: 2023

 

mehmet nur kaya | rheumatology | Best Researcher Award

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Dr. mehmet nur kaya | rheumatology | Best Researcher Award

Dr at gĆ¼lhane training and research hospital, Turkey

The study titledĀ ā€œImpact of Central Sensitization on Clinical and Functional Aspects of Psoriatic Arthritisā€Ā by Mehmet Nur Kaya et al. examines the prevalence of central sensitization (CS) in patients with psoriatic arthritis (PsA). Conducted with 103 PsA patients, the research used the Central Sensitization Inventory (CSI) to assess CSā€™s influence on clinical and functional markers such as disease activity, sleep quality, depression, and anxiety. The study found that 65.1% of the patients had CS, with the Psoriasis Area Severity Index (PASI), General Anxiety Disorder-7 (GAD-7), and Insomnia Severity Index (ISI) emerging as significant predictors of CS. Patients with CS demonstrated higher BMI and disease activity scores. The research highlights the importance of considering CS when assessing pain sensitivity in PsA patients. These findings underscore the potential impact of CS on clinical management, with implications for treatment strategies aimed at improving quality of life in PsA patients.

 

Publication profile

Scopus

šŸŽ“ Education

Dr. Mehmet Nur Kaya is a distinguished researcher in rheumatology, having earned his medical degree from a reputable institution. He pursued further specialization in rheumatology and is currently affiliated with the Rheumatology Department at GĆ¼lhane Training and Research Hospital, University of Health Sciences in Turkey. His commitment to understanding complex rheumatic diseases, especially psoriatic arthritis (PsA), reflects his dedication to advancing medical knowledge through continuous learning and hands-on experience.

šŸ‘Øā€āš•ļø Professional Experience

As a dedicated rheumatologist, Dr. Kaya has extensive experience in the study and management of PsA and other rheumatic conditions. His contributions to understanding the clinical and functional impacts of central sensitization (CS) on PsA patients are significant. He has led numerous observational studies focusing on pain sensitivity, quality of life, disease activity, and treatment outcomes. Utilizing patient-centric assessments like the Central Sensitization Inventory (CSI), Dr. Kaya has shaped treatment protocols, improving patient care and outcomes. His commitment to clinical expertise and research continues to enhance the quality of life for individuals affected by chronic inflammatory diseases.

šŸ”¬ Research Skills

Dr. Kaya possesses essential research skills that include:

Critical Thinking: Evaluating sources and synthesizing diverse viewpoints. Methodology Proficiency: Designing studies and collecting valid data using quantitative and qualitative approaches. Effective Communication: Clearly articulating findings through written reports and presentations. Organizational Skills: Managing research timelines and resources efficiently. Digital Tool Familiarity: Accessing and utilizing a wide range of resources. Ethical Considerations: Upholding integrity and confidentiality in research.

 

Publication

  1. Indices and ferritin level that predict organ involvement in adult-onset Still’s disease
    Authors: Kaya, M.N., KılıƧ, Ɩ., GĆ¼neş, E.Ƈ., Tecer, D., Yılmaz, S.
    Journal: Biomarkers in Medicine, 2024
    Citations: 0

 

  1. Drug-free remission is an achievable target with immunosuppressive treatment in idiopathic granulomatous mastitis
    Authors: Kaya, M.N., Tekgƶz, E., Ƈolak, S., Ƈınar, M., Yılmaz, S.
    Journal: Irish Journal of Medical Science, 2023, 192(6), pp. 2815ā€“2819
    Citations: 3

 

  1. Can pre-treatment inflammatory biomarker levels predict the response of tocilizumab therapy in COVID-19 patients?
    Authors: Kaya, M.N., Tecer, D., Ƈınar, M., Ƈolak, S., Yılmaz, S.
    Journal: Gulhane Medical Journal, 2023, 65(4), pp. 145ā€“151
    Citations: 1

 

  1. Hospital-acquired anemia in chronic kidney disease
    Authors: Kaya, M.N., Caner, B., Toprak, Ɩ.
    Journal: International Journal of Scientific and Technology Research, 2019, 8(4), pp. 160ā€“166
    Citations: 0

šŸ” Conclusion

Dr. Mehmet Nur Kaya is a dedicated and accomplished rheumatologist whose extensive clinical experience and significant research contributions make him an excellent candidate for the Best Researcher Award. His strengths, particularly in patient-centric research and commitment to advancing medical knowledge, position him as a leader in the field of rheumatology. By focusing on expanding his publication record, seeking funding opportunities, and fostering collaborative initiatives, Dr. Kaya can further elevate his contributions to rheumatology and improve the lives of those affected by chronic inflammatory diseases. His innovative approaches and commitment to patient care underscore his potential to make a lasting impact in the field.

Sakshi Kumari | Medicine | Young Scientist Award

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Sakshi Kumari | Medicine | Young Scientist Award

Dr Sakshi Kumari Shimoga institute of medical sciences India

Sakshi Kumari is a dedicated medical professional with a strong academic background, holding an MBBS from Shimoga Institute of Medical Sciences. Her extensive research experience includes studies on COVID-19 outcomes, cognitive dysfunction in postpartum women, and the impact of social media on medical students. She has actively participated in various national and international conferences, winning multiple awards for her presentations. In addition to her research, Sakshi has taken on leadership roles in medical organizations and engaged in community service. Her commitment to both medicine and social responsibility positions her as a promising future leader in healthcare.

    1. Title: Knowledge and Awareness Regarding Responsible Antibiotic Use Among the General Population of Shimoga District of Karnataka: A Cross-Sectional Study
      Authors: S. Wilson, R. Koppad, K. Nagendra, S. Kumari, C. Liana, C.A. Joseph
      Year: 2023

     

    1. Title: Test Positivity Rate, Contact History, and Vaccination Status of COVID-19 Among Patients Visiting Flu Corner (Fever Clinic) of a Tertiary Care Health Center of Karnataka
      Authors: S. Wilson, R. Koppad, K. Nagendra, S. Kumari, C. Liana, C.A. Joseph
      Year: 2023

     

    1. Title: Outcomes of Home Isolated COVID-19 Patients and Risk Factors Associated with the Adverse Outcomes: Longitudinal Retrospective Study in Shimoga, Karnataka
      Author: S. Kumari
      Year: 2023

     

    Conclusion

    In conclusion, Sakshi Kumari’s impressive academic achievements and diverse research experiences reflect her dedication to the medical field. Her active participation in conferences and leadership roles highlights her commitment to advancing healthcare and addressing pressing health issues. Through her community service initiatives, she demonstrates a strong sense of social responsibility. With her passion for medicine and proven skills, Sakshi is well-equipped to make significant contributions to the healthcare sector and drive positive change in the lives of others. Her future in medicine is promising, with the potential for impactful leadership and innovation.

Haseeb Sattar | Clinical Medicine | Best Faculty Award

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Assoc Prof Dr. Haseeb Sattar | Clinical MedicineĀ  | Best Faculty Award

Assoc Prof Dr Haseeb Sattar Urban Vocational College of Sichuan Chengdu China

Dr. Haseeb Sattar is a seasoned medical professional with extensive experience in clinical pharmacotherapy and internal medicine. He holds a PhD in Clinical Pharmacology from Huazhong University of Science and Technology, China, and has served as an Assistant Professor at several prestigious universities in China, teaching clinical subjects to international MBBS students. Dr. Sattar has a strong background in research, with numerous publications in leading medical journals. His career is distinguished by his commitment to medical education, research, and patient care, making him a valuable asset to any academic or clinical institution.

Publication profile

Scopus

Scholar

šŸŽ“ Education

PhD/DM in Clinical Pharmacology-Clinical Pharmacy – Tongji Medical College of Huazhong University of Science and Technology, China. Dates: September 2014 ā€“ June 2017. PG-Dip in Internal Medicine – University of Edinburgh, UK Dates: September 2018 ā€“ August 2020. MPhil in Medical Microbiology – Quaid-i-Azam University, Islamabad, Pakistan Dates: January 2012 ā€“ 2014. Doctor of Pharmacy (PharmD) – Riphah International University, Islamabad, Pakistan Dates: September 2005 ā€“ August 2010. Higher Secondary School Certificate (HSSC) – Federal Board of Intermediate & Secondary Education, Islamabad, Pakistan. Dates: August 2002 ā€“ August 2004. Diploma in Computer Hardware – Super Tech Institute of Computer Sciences Dates: May 2002 ā€“ August 2002. Secondary School Certificate (SSC) – Federal Board of Intermediate & Secondary Education, Islamabad, Pakistan Dates: March 2000 ā€“ March 2002

šŸ‘Øā€šŸ« Professional Experience

Assistant Professor of Medicine – Chengdu University of TCM, Chengdu, China Dates: September 2019 ā€“ Present Responsibilities: Teaching clinical subjects to foreign MBBS students. Assistant Professor of Medicine – Hubei University of Traditional Chinese Medicine, Wuhan, China Dates: September 2017 ā€“ July 2019 Responsibilities: Teaching clinical subjects to foreign MBBS students. Lecturer (Part-Time) – Hubei University of Nationality, Enshi, China Dates: July 2016 ā€“ July 2017. Responsibilities: Teaching internal medicine, diagnostics, pharmacology, preventive medicine, and infectious diseases. Lecturer of Clinical Pharmacotherapeutics and Clinical Practices – University of Lahore, Islamabad Campus Dates: September 2010 ā€“ September 2014 Responsibilities: Taking lectures, hospital ward rounds.

šŸ… Certifications

American Board Certification in Pharmacotherapy (BCPS), USA. American Board-Certified Cardiology Specialist (BCCP). Certification in Toxicology, Harvard Medical University, USA. Certification in Endocrine Emergencies, Harvard Medical University, USA. Certification in COPD Management, University of Pennsylvania School of Medicine, USA

šŸ“ Research Publications

Sattar, Haseeb, et al. “Role of glucuronidation pathway in quetiapine metabolism: An in vivo drugā€“drug interaction study between quetiapine and probenecid.” Saudi Journal of Medicine & Medical Sciences, 2020. Nie Q, Sattar H, et al. “An intramural left ventricular fistula caused by left ventriculography.” World Journal of Emergency Medicine, 2022. Luo Y, Jiang Q, Zhu Z, Sattar H, et al. “Phosphoproteomics and proteomics reveal metabolism as a key node in LPS-induced acute inflammation in RAW264. 7.” Inflammation, 2020.

šŸ† Achievements

Recipient of the Chinese Government Scholarship. Multiple scholarships during university (Mumtaz Scholarships)

Evaluation for Best Faculty Award šŸ†

Strengths for the Award:

Extensive Clinical and Academic Experience: Dr. Haseeb Sattar has over a decade of experience in clinical pharmacotherapy and internal medicine, with a strong foundation in both practical and theoretical aspects of the field. His roles in various academic institutions, particularly in teaching clinical subjects to MBBS students, demonstrate his commitment to education and student development. Diverse Educational Background: Dr. Sattar’s qualifications, including a Doctor of Pharmacy (PharmD), MPhil in Medical Microbiology, and PhD/DM in Clinical Pharmacology, provide him with a broad and in-depth understanding of medicine. His postgraduate diploma in Internal Medicine from the University of Edinburgh further solidifies his expertise. Research Accomplishments: With numerous publications in reputable journals, Dr. Sattar has contributed significantly to medical research. His work spans various topics, including pharmacotherapy, clinical pharmacy, and internal medicine, reflecting his active engagement in advancing medical knowledge. International Exposure: Dr. Sattar’s teaching and research experiences across Pakistan and China, coupled with certifications from prestigious institutions in the USA, highlight his global perspective and adaptability in different educational and healthcare environments. Recognition and Awards: Dr. Sattar has been the recipient of multiple scholarships, including the prestigious Chinese Government Scholarship, which underscores his academic excellence and recognition by international bodies.

Areas for Improvement:

Focused Research Themes: While Dr. Sattar has published extensively, focusing on a more specific research theme or developing a specialized niche could enhance his recognition in a particular area of medicine. Increased Collaboration: Engaging in more collaborative research with other international institutions and experts could further elevate his profile and contribute to broader scientific advancements. Leadership Roles: Taking on more leadership roles in academic or research institutions could showcase his ability to influence and guide future research directions and academic programs.

Publication top notes

  • Reactive Oxygen Speciesā€Mediated Tumor Microenvironment Transformation: The Mechanism of Radioresistant Gastric Cancer
    • Journal: Oxidative Medicine and Cellular Longevity
    • Year: 2018
    • DOI: 10.1155/2018/5801209
    • Contributors: H. Gu, T. Huang, Y. Shen, Y. Liu, F. Zhou, Y. Jin, H. Sattar, Y. Wei
    • Citations: 64

 

  • Co-existence of blaNDM-1 and blaKPC-2 in Clinical Isolates of Klebsiella pneumoniae from Pakistan
    • Journal: Journal of Chemotherapy
    • Year: 2016
    • Volume: 28(4), 346-349
    • Contributors: H. Sattar, M. Toleman, F. Nahid, R. Zahra
    • Citations: 35

 

  • The Prognostic Value of Long Noncoding RNAs in Prostate Cancer: A Systematic Review and Meta-Analysis
    • Journal: Oncotarget
    • Year: 2017
    • Volume: 8(34), 57755
    • Contributors: W. Ma, X. Chen, L. Ding, J. Ma, W. Jing, T. Lan, H. Sattar, Y. Wei, F. Zhou
    • Citations: 24

 

  • Natural Killer Cell Immunotherapy Against Multiple Myeloma: Progress and Possibilities
    • Journal: Journal of Leukocyte Biology
    • Year: 2018
    • Volume: 103(5), 821-828
    • Contributors: P. Liu, Y. Jin, H. Sattar, H. Liu, W. Xie, F. Zhou
    • Citations: 18

 

Conclusion:

Dr. Haseeb Sattar’s extensive clinical experience, robust academic background, and significant research contributions make him a strong candidate for the Best Faculty Award. His diverse expertise and international exposure, combined with his dedication to education and research, position him as an exemplary figure in the field of medicine. With a focus on further specialization and increased collaborative efforts, Dr. Sattar’s impact on the medical community is likely to grow, making him well-deserving of this recognition.

Mona Navaei-Nigjeh | Neural tissue engineering | Best Researcher Award

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Dr. Mona Navaei-Nigjeh | Neural tissue engineering | Best Researcher Award

Dr.Ā  Mona Navaei-Nigjeh Tehran University of Medical Sciences Iran

Mona Navaei-Nigjeh is a Ph.D. candidate in Biomedical Engineering specializing in tissue engineering at Tehran University of Medical Sciences. With a strong academic background, including a B.Sc. in Biology and an M.Sc. in Biomedical Engineering, she has garnered multiple awards for her research excellence. Her work focuses on advanced cell culture, molecular biology, and regenerative medicine. Mona has extensive experience as a research assistant and has published numerous peer-reviewed articles. She is also a member of elite societies like the Iran’s National Elites Foundation and the Iranian Tissue Engineering and Regenerative Medicine Society.

Publication Profile

Scholar

 

šŸ† Strengths for the Award:

  1. Academic Excellence: Consistent top performance in her B.Sc., M.Sc., and Ph.D. programs with outstanding grades.
  2. Awards and Honors: Recognition as the best researcher and poster presenter in several prominent national scientific festivals and conferences.
  3. Research Publications: Authored or co-authored over 20 publications in high-impact journals, with topics ranging from tissue engineering to molecular biology.
  4. Technical Expertise: Proficient in advanced techniques such as 3D cell culture, flow cytometry, real-time PCR, and scaffold fabrication, which are critical for high-impact research in her field.
  5. Professional Affiliations: Active membership in elite national and international research societies, which enhances her research network and collaboration opportunities.

šŸ“ˆ Areas for Improvement:

  1. International Recognition: While she has been recognized nationally, gaining international research awards or invitations to global conferences would further strengthen her profile.
  2. Leadership Roles: Taking on more leadership positions, such as principal investigator roles or heading research teams, could showcase her as an emerging leader in her field.

Educational Background šŸŽ“

B.Sc. in Biology Tehran University, Tehran, Iran 2005-2009 GPA: 16.39/20. M.Sc. in Biomedical Engineering (Tissue Engineering)
Tehran University, Tehran, Iran 2010-2012 GPA: 19.06/20. Ph.D. in Biomedical Engineering (Tissue Engineering) Tehran University of Medical Sciences, Tehran, Iran Ongoing GPA: 18.94/20

Honors and Achievements šŸ…

Member of Iran’s National Elites Foundation (INEF). Member of the Iranian Tissue Engineering and Regenerative Medicine Society (ITERMS). Best Researcher Award, Avicenna Student Festival, Tehran University of Medical Sciences, 2016. Best Poster Awards, various congresses (2015-2016). Outstanding Researcher and Graduate Student, Faculty of New Sciences and Technologies, University of Tehran, 2012. Top Student Awards in B.Sc. and M.Sc. at University of Tehran

Work Experience šŸ’¼

Research Assistant Tehran University of Medical Sciences (2 years). Scientific and Executive Role Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Tehran University of Medical Sciences (6 years). Scientific Activity Brain and Spinal Injury Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences (1 year)

Research Experience šŸ”¬

M.Sc. Thesis: ā€œ3D Culture of Differentiated Human Endometrial Stem Cells into Neuronsā€. Ph.D. Thesis: ā€œEffect of Co-Transplantation of Encapsulated Pancreatic Islets with Mesenchymal Stem Cells within Hydrogel as a Treatment for Diabetes Mellitus in Adult Ratsā€

Workshops šŸ› ļø

  • Elisa Technique, Flow Cytometry, Real-time PCR
    The Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Tehran University of Medical Sciences (2016)

Technical Experience šŸ§Ŗ

Cellular Biology: Culturing various stem cells and cell lines. Molecular Biology: DNA/RNA extraction, RT-PCR, Real-time PCR. Immunology: Immunocytochemistry, Flow Cytometry. Microscopy: Stereo, Fluorescence, and Light Microscopy. Histology: Sample preparation for microscopy and immunohistochemistry. Biochemistry: ELISA, Enzymatic Assays. Tissue Engineering: Fabrication of 3D scaffolds using Electrospinning, Freeze Drying, and Self-assembly

Publication Top NotesĀ 

  • Antibacterial properties of a bacterial cellulose CQD-TiO2 nanocomposite
    • Authors: S. Malmir, A. Karbalaei, M. Pourmadadi, J. Hamedi, F. Yazdian, M. Navaee
    • Journal: Carbohydrate Polymers
    • Year: 2020
    • Citations: 137

 

  • Preparation of pH-sensitive chitosan/polyvinylpyrrolidone/Ī±-Fe2O3 nanocomposite for drug delivery application: Emphasis on ameliorating restrictions
    • Authors: S.E. Gerami, M. Pourmadadi, H. Fatoorehchi, F. Yazdian, H. Rashedi, …
    • Journal: International Journal of Biological Macromolecules
    • Year: 2021
    • Citations: 116

 

  • Ameliorating quercetin constraints in cancer therapy with pH-responsive agarose-polyvinylpyrrolidone-hydroxyapatite nanocomposite encapsulated in double nanoemulsion
    • Authors: A. Samadi, M. Pourmadadi, F. Yazdian, H. Rashedi, M. Navaei-Nigjeh
    • Journal: International Journal of Biological Macromolecules
    • Year: 2021
    • Citations: 91

 

  • Antiapoptotic effects of cerium oxide and yttrium oxide nanoparticles in isolated rat pancreatic islets
    • Authors: A. Hosseini, M. Baeeri, M. Rahimifard, M. Navaei-Nigjeh, A. Mohammadirad, …
    • Journal: Human & Experimental Toxicology
    • Year: 2013
    • Citations: 83

 

  • Improvement of isolated rat pancreatic islets function by combination of cerium oxide nanoparticles/sodium selenite through reduction of oxidative stress
    • Authors: N. Pourkhalili, A. Hosseini, A. Nili-Ahmadabadi, M. Rahimifard, …
    • Journal: Toxicology Mechanisms and Methods
    • Year: 2012
    • Citations: 77

 

  • Protective effects of cerium oxide and yttrium oxide nanoparticles on reduction of oxidative stress induced by sub-acute exposure to diazinon in the rat pancreas
    • Authors: M.R. Khaksar, M. Rahimifard, M. Baeeri, F. Maqbool, M. Navaei-Nigjeh, …
    • Journal: Journal of Trace Elements in Medicine and Biology
    • Year: 2017
    • Citations: 71

 

  • Synthesis and characterization of chitosan/polyvinylpyrrolidone coated nanoporous Ī³-Alumina as a pH-sensitive carrier for controlled release of quercetin
    • Authors: E. Nematollahi, M. Pourmadadi, F. Yazdian, H. Fatoorehchi, H. Rashedi, …
    • Journal: International Journal of Biological Macromolecules
    • Year: 2021
    • Citations: 68

 

  • PVA based nanofiber containing CQDs modified with silica NPs and silk fibroin accelerates wound healing in a rat model
    • Authors: S. Abolghasemzade, M. Pourmadadi, H. Rashedi, F. Yazdian, S. Kianbakht, …
    • Journal: Journal of Materials Chemistry B
    • Year: 2021
    • Citations: 68

 

  • The synthesis and characterization of double nanoemulsion for targeted Co-Delivery of 5-fluorouracil and curcumin using pH-sensitive agarose/chitosan nanocarrier
    • Authors: M. Pourmadadi, M. Ahmadi, M. Abdouss, F. Yazdian, H. Rashedi, …
    • Journal: Journal of Drug Delivery Science and Technology
    • Year: 2022
    • Citations: 67

 

  • Chitosan/agarose/graphitic carbon nitride nanocomposite as an efficient pH-sensitive drug delivery system for anticancer curcumin releasing
    • Authors: M. Rajabzadeh-Khosroshahi, M. Pourmadadi, F. Yazdian, H. Rashedi, …
    • Journal: Journal of Drug Delivery Science and Technology
    • Year: 2022
    • Citations: 66

 

āœ… Conclusion:

Mona Navaei-Nigjehā€™s profile demonstrates excellence in academic research, consistent recognition, and contributions to the field of tissue engineering. Her research output and technical skills make her a deserving candidate for the Best Researcher Award. Further international exposure and leadership roles would make her even more competitive for prestigious global awards.

 

Katherine SimbaƱa Rivera | Biomedicina | Young Scientist Award

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Dr. Katherine SimbaƱa Rivera | Biomedicina | Young Scientist Award

Assistant Professor at Pontificia Universidad CatĆ³lica del Ecuador, Ecuador

Summary:

Katherine SimbaƱa Rivera is a medical doctor and researcher dedicated to advancing medical knowledge and public health initiatives through extensive research and collaborative networks. With a background in molecular biomedicine and significant experience in health research management, she has authored numerous articles and co-authored books on critical health topics. Her leadership in national health research and active involvement in student scientific societies underline her commitment to fostering research capabilities and promoting healthcare access in underserved communities across Latin America.

Profile:

Scopus

Orcid

Google Scholar

šŸŽ“Education:

Katherine SimbaƱa Rivera earned her medical degree from Universidad Central del Ecuador. She further pursued a Master’s degree in Molecular Biomedicine, specializing in Basic and Translational Cancer Research, from the Universitat de Barcelona, Spain. Currently, she is enrolled in doctoral studies in Applied Health Sciences Research at the University Institute of Biomedical and Health Research (IUIBS) at Universidad de Las Palmas de Gran Canaria, Spain.

šŸ„šŸ‘Øā€šŸ«Professional Experience:

From 2021 to 2022, Katherine served as the National Director of Health Research at the Ecuadorian Ministry of Public Health, where she played a key role in drafting nine research and bioethics regulations and developing strategic guidelines for national health management. She is currently an associate researcher at the Center for Research on Health in Latin America (CISeAL) at Pontificia Universidad CatĆ³lica del Ecuador (PUCE).

Research Interests:

Katherine SimbaƱa Rivera’s research interests encompass a broad spectrum, including the Ecuadorian pharmaceutical market, COVID-19, translational cancer research, and applied health sciences. Her work focuses on advancing public health through innovative research methodologies and strategic health interventions.

Publications Top Notes šŸ“:

1. Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review

  • Authors: Ortiz-Prado, E., SimbaƱa-Rivera, K., GĆ³mez-Barreno, L., Rubio-Neira, M., …
  • Journal: Diagnostic Microbiology and Infectious Disease
  • Volume: 98
  • Issue: 1
  • Year: 2020
  • Article Number: 115094
  • Citations: 543

2. Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador

  • Authors: Ortiz-Prado, E., SimbaƱa-Rivera, K., Barreno, L.G., Diaz, A.M., Barreto, A., …
  • Journal: PLoS Neglected Tropical Diseases
  • Volume: 15
  • Issue: 1
  • Year: 2021
  • Article Number: e0008958
  • Citations: 171

3. Anxiety and depression in patients with confirmed and suspected COVID-19 in Ecuador

  • Authors: Paz, C., Mascialino, G., Adana DĆ­az, L., RodrĆ­guez Lorenzana, A., …
  • Journal: Psychiatry and Clinical Neurosciences
  • Volume: 74
  • Issue: 10
  • Year: 2020
  • Pages: 554-555
  • Citations: 109

4. Behavioral and sociodemographic predictors of anxiety and depression in patients under epidemiological surveillance for COVID-19 in Ecuador

  • Authors: Paz, C., Mascialino, G., Adana-DĆ­az, L., RodrĆ­guez-Lorenzana, A., …
  • Journal: PLoS One
  • Volume: 15
  • Issue: 9
  • Year: 2020
  • Article Number: e0240008
  • Citations: 80

5. The disease burden of suicide in Ecuador, a 15 yearsā€™ geodemographic cross-sectional study (2001ā€“2015)

  • Authors: Ortiz-Prado, E., SimbaƱa, K., GĆ³mez, L., Henriquez-Trujillo, A.R., …
  • Journal: BMC Psychiatry
  • Volume: 17
  • Issue: 1
  • Year: 2017
  • Pages: 1-11
  • Citations: 56

 

Hao Chi | clinical medicine | Young Scientist Award

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Ā Mr. Hao Chi |Electoral Studies | Best Researcher AwardĀ 

Dr. Hao Chi, MD, is affiliated with the Clinical Medical College at Southwest Medical University in Luzhou, China. With an H-index of 21 and 1069 citations, Dr. Chi is a prolific researcher focusing on programmed cell death, therapy resistance in cancers, immune microenvironment, advanced data analysis, and exosomal dynamics in tumor ecology. He has contributed to numerous high-impact journals and serves on editorial boards and as a guest editor for several scientific publications. Dr. Chi’s expertise in utilizing cutting-edge sequencing technologies and bioinformatics positions him at the forefront of cancer research and personalized medicine.

Profile

Scholar

Education šŸŽ“

MD, Clinical Medicine
Southwest Medical University, Luzhou 646000, China

Research Experiences and Interests šŸ”¬

Programmed Cell Death and Tumor Prognosis Investigating the mechanisms of programmed cell death and their relevance to tumor prognosis.
Publications: Frontiers in Genetics 2022, Cells 2022, Frontiers in Molecular Biosciences 2023. Molecular Mechanisms of Therapy Resistance of Cancers Studying genetic, epigenetic, and immune system factors leading to cancer cell resistance to treatments. Publications: Journal of Medical Virology 2023, Frontiers in Immunology 2023. Immune Microenvironment and Cancer Prognostication Analyzing the tumor immune microenvironment to identify prognostic markers. Publications: Frontiers in Immunology 2022, 2023. Advanced Data Analysis in Disease Applying machine learning to diagnose and prognose diseases using multi-omics data. Publications: Frontiers in Endocrinology 2022, Tumour Virus Research 2023, Frontiers in Oncology 2023. Single-Cell and High-Throughput Sequencing Technologies Utilizing sequencing technologies to explore tumor microenvironment and therapeutic responses. Publications: Frontiers in Immunology 2023, Frontiers in Molecular Biosciences 2023, Frontiers in Pharmacology 2023. Exosomal Dynamics in Tumor Ecology Investigating the role of exosomes in cancer progression and their therapeutic potential. Publications: Journal of Oncology 2022, Frontiers in Immunology 2022, 2023.

Skills šŸ› ļø

  1. Data Analysis
    • Proficient in R language and bioinformatics for processing and visualizing patient data from TCGA, GEO, ICGC, and CGGA.
    • Integrating high-throughput sequencing data, single-cell sequencing data, and spatial transcriptome data.
  2. Cellular and Molecular Biology
    • Designing and performing cellular phenotyping experiments.
    • Cell culture and transfection.
    • Techniques: PCR, WB, IHC, transfection, MTT, Edu assay, CCK8, transwell assay, wound healing assay, colony formation assay, flow cytometry.
  3. Animal Experiments
    • In vivo experiments, including subcutaneous tumor formation, tumor tissue collection, and physiological monitoring.

Academic Positions šŸ§‘ā€šŸ«

  1. Editorial Board Member
    • Discover Immunity (2024)
    • BMC Cancer (2023-present)
    • Discover Oncology (2023-present)
    • iMeta (2023-present)
  2. Guest Editor
    • Discover Oncology (2024)
    • Current Protein & Peptide Science (2024)
    • Current Genomics (2024)
    • Frontiers in Immunology (2024)
    • Current Cancer Drug Targets (2024)
    • Current Gene Therapy (2024)
    • Journal of Visualized Experiments (2023)
  3. Editorial Review Board Member
    • Oncology Research (2024)
    • Technology in Cancer Research & Treatment (2024.02-present)
    • Cancer Control (2024.02-present)
  4. Reviewer
    Journals including International Journal of Surgery, European Journal of Internal Medicine, Cancer Letters, Cell Communication and Signaling, Computers in Biology and Medicine, iScience, Inflammation Research, Environmental Toxicology, Scientific Reports, Heliyon, Frontiers in Immunology, Aging, Discover Oncology, Journal of Gene Medicine, BMC Bioinformatics, BMC Medical Genomics, BMC Cancer, BMC Pulmonary Medicine, Functional & Integrative Genomics, Archives of Dermatological Research, Journal of Orthopaedic Surgery and Research, Molecular and Cellular Biochemistry, PLOS ONE, Current Pharmaceutical Design, Open Life Sciences, JOVE, Medicine, Frontiers in Pharmacology, Frontiers in Genetics, Frontiers in Oncology, Frontiers in Surgery, Frontiers in Aging Neuroscience, Frontiers in Neuroscience, Frontiers in Molecular Biosciences, Frontiers in Public Health, Gene, Journal of Cancer, Acta Oncologica, Journal of the COPD Foundation, Cell Biology International, Oncology Research, Artificial Intelligence in Medicine, Expert Opinion on Drug Safety, Pharmaceutical Biology, Experimental Cell Research, Current Drug Targets, Journal of Inflammation Research, Journal of Stroke and Cerebrovascular Diseases, iMeta, Turkish Journal of Gastroenterology, Pharmaceutical Biology, Journal of Pain Research, World Journal of Urology, International Journal of Molecular Medicine, Diabetes, Obesity and Metabolism, Annals of Medicine, Technology in Cancer Research & Treatment, Acta Psychologica, OncoTargets and Therapy.

Oral Presentations šŸŽ¤

Invited Speaker, “Guidance on University Students’ Innovation and Entrepreneurship Projects,” Scientific Research Department of Southwest Medical University, Luzhou, China, March 2023. Workshop Conductor, “Integrating High-Throughput Sequencing Data with Machine Learning,” Sino-German Laboratory at the Affiliated Hospital of Southwest Medical University, Luzhou, China, May 2023. Presenter, Summer Research Symposium, General Hospital of the People’s Liberation Army, “Integration of Modern Medicine with Acupuncture and Moxibustion Research,” Beijing, China, May 2023. Featured Speaker, Fall Research Symposium, Beijing University of Chinese Medicine, “Advances in Breast Cancer by Single Cell Sequencing,” Beijing, China, July 2023. Keynote Speaker, “Single-Cell Sequencing: Implications for Precision Medicine,” The Affiliated Hospital of Southwest Medical University, Luzhou, China, June 2023. Invited Speaker, “Multi-Omics and Machine Learning: A New Era in Disease Understanding,” Chongqing Biomarkers Committee, Chongqing, China, October 2023. Invited Speaker, “Macao University of Science and Technology (MUST) Faculty of Medicine Chinese Medicine Master Teachers Forum Meeting,” Macau University of Science and Technology, Macau, China, October 2023.

Book Publications šŸ“š

  • Deputy Editor: Clinical Research on Chinese Medicine Treatment for Diabetes Mellitus, Shanghai Jiao Tong University Press, Shanghai, China, 2023.

Publications Top Notes šŸ“

  • Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC
    • Authors: H. Chi, X. Xie, Y. Yan, G. Peng, D.F. Strohmer, G. Lai, S. Zhao, Z. Xia, G. Tian
    • Journal: Frontiers in Immunology, 2022
    • Citations: 79

 

  • A novel anoikis-related gene signature predicts prognosis in patients with head and neck squamous cell carcinoma and reveals immune infiltration
    • Authors: H. Chi, P. Jiang, K. Xu, Y. Zhao, B. Song, G. Peng, B. He, X. Liu, Z. Xia, G. Tian
    • Journal: Frontiers in Genetics, 2022
    • Citations: 79

 

  • T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
    • Authors: H. Chi, S. Zhao, J. Yang, X. Gao, G. Peng, J. Zhang, X. Xie, G. Song, K. Xu
    • Journal: Frontiers in Immunology, 2023
    • Citations: 63

 

  • Identification and validation of neurotrophic factor-related gene signatures in glioblastoma and Parkinsonā€™s disease
    • Authors: S. Zhao, H. Chi, Q. Yang, S. Chen, C. Wu, G. Lai, K. Xu, K. Su, H. Luo, G. Peng
    • Journal: Frontiers in Immunology, 2023
    • Citations: 54

 

  • Circadian rhythm-related genes index: A predictor for HNSCC prognosis, immunotherapy efficacy, and chemosensitivity
    • Authors: H. Chi, J. Yang, G. Peng, J. Zhang, G. Song, X. Xie, Z. Xia, J. Liu, G. Tian
    • Journal: Frontiers in Immunology, 2023
    • Citations: 5

 

  • Identification of copper metabolism-related subtypes and establishment of the prognostic model in ovarian cancer
    • Authors: S. Zhao, X. Zhang, F. Gao, H. Chi, J. Zhang, Z. Xia, C. Cheng, J. Liu
    • Journal: Frontiers in Endocrinology, 2023
    • Citations: 52

 

  • Cuprotosis programmed-cell-death-related lncRNA signature predicts prognosis and immune landscape in PAAD patients
    • Authors: H. Chi, G. Peng, R. Wang, F. Yang, X. Xie, J. Zhang, K. Xu, T. Gu, X. Yang
    • Journal: Cells, 2022
    • Citations: 47

 

  • IL-7: A promising adjuvant ensuring effective T cell responses and memory in combination with cancer vaccines?
    • Authors: Y. Zhao, K. Wei, H. Chi, Z. Xia, X. Li
    • Journal: Frontiers in Immunology, 2022
    • Citations: 42

 

  • Exosomes: A potential tool for immunotherapy of ovarian cancer
    • Authors: X. Gong, H. Chi, D.F. Strohmer, A.T. Teichmann, Z. Xia, Q. Wang
    • Journal: Frontiers in Immunology, 2023
    • Citations: 40

 

  • A bioinformatics-based analysis of an anoikis-related gene signature predicts the prognosis of patients with low-grade gliomas
    • Authors: S. Zhao, H. Chi, W. Ji, Q. He, G. Lai, G. Peng, X. Zhao, C. Cheng
    • Journal: Brain Sciences, 2022
    • Citations: 40

 

Daniele Florio | Pharmaceutical science | Young Scientist Award

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Mr. Daniele Florio | Pharmaceutical science | Young Scientist Award

Daniele Florio is a dedicated researcher in pharmaceutical sciences, currently pursuing a Ph.D. at the University of Naples Federico II. His doctoral work focuses on integrated molecular approaches targeting mutated Nucleophosmin 1 in Acute Myeloid Leukemia, scheduled for completion in October 2024. Daniele brings extensive experience from his Marie Sklodowska-Curie secondment and voluntary internship, specializing in peptide synthesis, mass spectrometry, and spectroscopic techniques. With a strong publication record and active participation in international conferences, he contributes significantly to the fields of amyloid aggregation, chemical catalysis, and drug development, showcasing advanced skills in scientific research and analysis.

Profile

Scopus

šŸ‘Øā€šŸ«Professional Experience

Tutoring Activities (Grant Type B) 2023-2024, Naples, Italy, Department of Pharmacy, University of Naples Federico II, Provided supplementary teaching for Chemistry and Inorganic Chemistry courses for Pharmacy and CTF degree students. Ph.D. Candidate in Pharmaceutical Sciences (XXXVII Cycle) 2021 ā€“ Present, Naples, Italy, Department of Pharmacy, University of Naples Federico II, PhD Project: Integrated molecular approaches targeting mutated Nucleophosmin 1 in Acute Myeloid Leukemia., Scheduled PhD end: October 31, 2024. Secondee under Marie Skłodowska-Curie Research and Innovation Staff Exchange Action June 2022 ā€“ March 2023, Dublin, Ireland, Keladapharmachem, Participated in the GreenX4Drug (EU funded H2020 RISE project), focusing on developing novel asymmetric chemical catalysts for manufacturing high-value APIs and advanced intermediates.. Voluntary Internship Post-Degree 2018 ā€“ 2019, Naples, Italy, Department of Pharmacy, University of Naples Federico II, Designed, synthesized, and characterized peptides, peptidomimetics, and small molecules using solid-phase and solution methodologies. Utilized mass spectrometry (ESI) for identifying synthetic compounds and applied analytical and preparative methodologies (HPLC) for their purification and characterization. Conducted structural and functional characterization of biomolecules through spectroscopic techniques (CD, Fluorescence, SPR, UV-Vis). Supervisor: Prof. Daniela Marasco

šŸŽ“Education and Training

Biologist Board Examination February 7, 2022, University of Naples Federico II, Naples, Italy Masterā€™s Degree in Biological Science (Molecular Diagnostics Field) July 12, 2021, Naples, Italy Department of Pharmacy, University of Naples Federico II Experimental Thesis: “Protein fragments of Nucleophosmin 1 as models of amyloids”, Supervisor: Prof. Antonello Merlino, Co-Supervisor: Prof. Daniela Marasco,k Grade: 110/110. Bachelorā€™s Degree in Biological Science (Molecular Diagnostics Field) March 15, 2018, Naples, Italy Department of Pharmacy, University of Naples Federico II Experimental Thesis: “Amyloid-like aggregation of Nucleophosmin 1 regions related to Acute Myeloid Leukemia: spectroscopic studies” Supervisor: Prof. Daniela Marasco Grade: 106/110

šŸ“–Certifications

English TELSA C1, Grade B Language Certification ESAT, Malta Further & Higher Education Authority

Skills and Competencies

Organizational Skills

  • Efficient under pressure.
  • Adaptive to changes and new situations.
  • Strong independent work organization and goal achievement.

Job-related Skills

  • Solid-phase peptide synthesis and combinatorial peptide libraries using Fmoc/Boc chemistry.
  • Experience with various peptide synthesizers (BIOTAGE, Liberty Blue 2.0).
  • Proficient in analysis and purification using ESI mass spectrometry, HPLC, and flash purification systems.
  • Skilled in spectroscopic techniques (CD, Fluorescence, DLS, SPR, UV-Vis, FTIR, NMR).

Digital Skills

  • Proficient in Microsoft Office Suite.
  • Experienced with operating systems: MS-Windows, MacOS, LINUX.
  • Proficient in scientific data analysis software (GraphPad Prism).
  • Knowledgeable in databases (PubMed) and bibliographic management software (EndNote, Mendeley).
  • Proficient with video conferencing software (Teams, Skype, Zoom, Google Meet).
  • Excellent knowledge of major browsers (Edge, Chrome, Firefox, Safari, Opera).

šŸŒProjects

National Project Participation

  • BANDO-PRIN-2022. Research Project: Design, synthesis, and investigation of novel G-quadruplex aptamers against STAT3 and the interleukin-6 receptor (G4-APTASTAT).
  • Project Coordinator and Head of Research Unit: Prof. GALEONE Aldo

Bibliometric Parameters

  • H-index from Scopus: 11
  • Number of Publications: 24
  • Citations: 388

 

Publications Top Notes šŸ“

  • The effects of histidine substitution of aromatic residues on the amyloidogenic properties of the fragment 264ā€“277 of nucleophosmin 1
    • Authors: D. Florio, P. Luciano, C. Di Natale, D. Marasco
    • Journal: Bioorganic Chemistry
    • Volume: 147
    • Year: 2024
    • Pages: 107404

 

  • Could Targeting NPM1c+ Misfolding Be a Promising Strategy for Combating Acute Myeloid Leukemia?
    • Authors: D. Florio, D. Marasco
    • Journal: International Journal of Molecular Sciences
    • Volume: 25
    • Issue: 2
    • Year: 2024
    • Pages: 811

 

  • Modulation of hydrogel networks by metal ions
    • Authors: S. La Manna, D. Florio, C. Di Natale, D. Marasco
    • Journal: Journal of Peptide Science
    • Volume: 29
    • Issue: 8
    • Year: 2023
    • Article ID: e3474

 

  • Ruthenium complexes bearing glucosyl ligands are able to inhibit the amyloid aggregation of short histidine-peptides
    • Authors: D. Florio, S. La Manna, A. Annunziata, M. Monti, D. Marasco
    • Journal: Dalton Transactions
    • Volume: 52
    • Issue: 25
    • Year: 2023
    • Pages: 8549ā€“8557

 

  • Insights into Network of Hot Spots of Aggregation in Nucleophosmin 1
    • Authors: D. Florio, S. La Manna, C. Di Natale, A.M. Malfitano, D. Marasco
    • Journal: International Journal of Molecular Sciences
    • Volume: 23
    • Issue: 23
    • Year: 2022
    • Pages: 14704

 

  • Hydrogelation tunability of bioinspired short peptides
    • Authors: S. La Manna, D. Florio, V. Panzetta, C. Di Natale, D. Marasco
    • Journal: Soft Matter
    • Volume: 8
    • Year: 2022
    • Pages: 8

 

Angelika Długosz-Pokorska | cancer research | Women Researcher Award

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Ā Dr. Angelika Długosz-Pokorska | cancer research |Women Researcher Award

Ā Dr at Medical University of ÅĆ³dÅŗ,Ā  Poland

A dedicated researcher and project leader at the Medical University of Lodz, Poland, with expertise in pharmacological characterization and anticancer drug development. As Principal Investigator and Co-investigator, led projects funded by prestigious grants like OPUS and SONATA, focusing on opioid peptide analogs and alpha-methylidene-delta-lactones. Supervising international student exchanges and engaging in expert activities, workshops, and editorial work. Recognized with numerous awards for scientific excellence, including Rector’s Awards and IF=8.638 for publication series on opioid mimetics and glutathione peroxidase. Committed to advancing medical science through innovative research and academic leadership.

Profile

  1. Scopus

 

  1. Orcid

šŸ“œ Employment History:

Research Associate (2017-present) Medical University of Lodz, Poland; Faculty of Medicine. Co-investigator (2016-2021)
Project: Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple receptors
Grant: OPUS 9, project ID 2015/17/B/ST5/00153. Principal Investigator (2016-2021) Project: Analysis of the anticancer activity of new synthetic alpha-methylidene-delta-lactones in selected cell lines Grant: SONATA, project ID 2015/17/D/NZ3/02226. Supervisor, Project Manager, and Principal Investigator (2018-present) Project: Analysis of the anticancer activity and molecular mechanism of action of new hybrid molecules containing uracil skeleton with an exo-cyclic methylene group Grant: PRELUDIUM13, project ID UMO-2017/25/N/NZ3/01039

šŸ“š Short Research Training:

University of Rouen, France (2014) Laboratoire de Neuropsychopharmacologie ExpƩrimentale

šŸŒ Activities:

  • Expert Activity/Reviewer (2024)
    Platform: Qeios
  • International Student Exchanges and ERASMUS Supervision (2024)
    Engaging in initiatives and participating in European Union programs, overseeing ERASMUS students.
  • Participation in Scientific Workshops and Research Teams (2024)
    Engaging in workshops aimed at exchanging experiences, self-improvement, and organization.
  • Editorial Work (2023-present)
    Journal: Reviewer for Breast Cancer-Tokyo, ISSN 1340-6868, eISSN 1880-4233.

šŸ† Awards and Distinctions:

2022: First-level Special Award for Outstanding Didactic Work by Academic Teachers Medical University of Lodz.

2020: Team Distinction from the Faculty of Chemistry Nicolaus Copernicus University in Toruń Rector’s Award Medical University of Lodz Second-degree scientific award for a series of publications titled: ‘Investigation of the Anticancer Properties of Synthetic Analogues of Compounds Isolated from Plants’. (Impact Factor – 8.034). Polish Intelligent Development Award – Nomination.

2019: Investigation of Anticancer Activity of Synthetic Analogues of Methylenolactones”, IF=4.026PTBioch Bursary Scholarship 44th FEBS Congress “From Molecules to Living Systems”. Rector’s Award Medical University of Lodz Second Prize for Publication: ‘Synthetic Analogues of Coumarin as Novel Agents with Anticancer Activity’. (Impact Factor = 4.173). Rector’s Award Medical University of Lodz Team Second award for Publication Series:

2017: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Synthesis and Investigation of Biological Activity of Opioid Mimetics and Glutathione Peroxidase”. (IF=8.638). Rector’s Award Medical University of Lodz Team First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Dicoumarins”. (IF=6.221) “Investigation of Anticancer Activity of Sesquiterpene Lactones”. (IF=4.994)

2016: Rector’s Award Medical University of Lodz First Prize for Publication Series: “Anticancer Properties of Novel Synthetic Lactones in Combination with Known Anticancer Drugs”. (IF = 8.835)

Publications Top Notes šŸ“

  • Title: Synthesis of New Chiral Ī²-Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluation-Part I
    • Authors: Laskowska, A., Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., et al.
    • Journal: Materials
    • Year: 2024
    • Volume: 17
    • Pages: 1ā€“15
    • Summary: This study focuses on the synthesis of new chiral Ī²-carbonyl selenides and evaluates their antioxidant and anticancer activities, providing valuable insights into potential therapeutic agents.

 

  • Title: New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF7 Cancer Cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Biologics: Targets and Therapy
    • Year: 2023
    • Volume: 17
    • Pages: 69ā€“83
    • Summary: This article presents a novel uracil analog with potential to reverse resistance to Taxol in MCF7 cancer cells, indicating its promising role as an anticancer agent.

 

  • Title: New Uracil Analog- U-359 can Reverse Resistance to Taxol in MCF-7 cancer cells
    • Authors: Długosz-Pokorska, A., Perlikowska, R., Janecki, T., et al.
    • Journal: Acta Biochimica Polonica
    • Year: 2023
    • Volume: 70
    • Pages: 56
    • Summary: This study explores another uracil analog’s potential to reverse resistance to Taxol in MCF-7 cancer cells, indicating a promising avenue for further research.

 

  • Title: The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides
    • Authors: Pacuła-Miszewska, A.J., Obieziurska-Fabisiak, M., Jastrzębska, A., et al.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Pages: 1ā€“11
    • Summary: This research investigates the impact of long carbon chains on the antioxidant and anticancer properties of N-substituted benzisoselenazolones and corresponding diselenides, providing valuable insights into structure-activity relationships.

 

  • Title: Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics
    • Authors: Laskowska, A., Pacuła-Miszewska, A., Długosz-Pokorska, A., et al.
    • Journal: Materials
    • Year: 2022
    • Volume: 16
    • Pages: 1ā€“14
    • Summary: This study explores the modification of GPx mimetics’ activity through the attachment of chiral functional groups, offering potential strategies for enhancing therapeutic effects.

 

Antonios Kousaxidis | Medicinal Chemistry | Best Researcher Award

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Ā Mr. Antonios Kousaxidis | Medicinal Chemistry |Best Researcher Award

Ā Mr at School of Pharmacy, Aristotle University of Thessaloniki, Greece

A seasoned educator and researcher with extensive experience in physics, holding positions from Assistant to Associate Professor at IAU, Urmia, and Urmia University of Technology. Specialized in teaching a range of undergraduate to Ph.D. courses including Quantum Mechanics, Laser Physics, and Nonlinear Dynamical Systems. Proficient in Maple and Matlab programming with a strong background in finite element method analysis. Led impactful research projects in chaotic systems, cancer treatment, and national security, earning multiple awards including the Kharazmi Scientific Festival Second Prize. A recognized leader in academia with a commitment to advancing scientific knowledge and education.

Profile

  1. Scopus

šŸŽ“ Education:

Masterā€™s Degree in Medicinal Chemistry: (9.85/10) from Departments of Chemistry, Medicine, Biological Applications and Technology, University of Ioannina, 45110, Ioannina, Greece.Ā Bachelor’s Degree in Chemistry: (7.76/10) from Department of Chemistry, School of Sciences, University of Ioannina, 45110, Ioannina, Greece.

Personal Skills:

Synthetic Organic Chemistry and Biochemistry: Training in synthetic organic chemistry and biochemistry applied to drug design, with experience in several areas of synthetic methodology using retrosynthetic approaches. Metal-Based Coupling Reactions: Excellent knowledge and practice of metal-based coupling reactions in modern organic chemistry. Synthetic Routes Optimization: Training in synthetic routes optimization using one-pot reactions during masterā€™s thesis. Analytical Methods: Proficient in NMR, IR, UV, and mass spectrometry for identifying organic compounds. Small Molecule Synthesis: Synthesis of small molecule organic compounds and isolation by recrystallization. Purification and Separation: Excellent knowledge and practice in chromatographic methods like column, preparative, and thin-layer chromatography for purifying and separating organic compounds. Biochemical Protocols: Good practice in using biochemical protocols for enzyme kinetics experiments. Drug Discovery Programs: Extensive experience in drug discovery programs, structure-based drug design, molecular docking, and SAR estimation models using in silico methods (Discovery Studio, Chimera, LigandScout, PyMOL, OpenBabel, ADMET). Scientific Manuscripts: Proficient in writing and preparing scientific manuscripts.

šŸ’» Software Skills:

Office Suite (ECDL degree) – Word processing, spreadsheets, presentations, etc. Calculative and predictive programs like MestReNova, Topspin DataAnalysis, ChemDraw Ultra, MedChem Designer, and BioLoom.

Research Focus:

A. Kousaxidis primarily focuses on the design and synthesis of novel compounds with therapeutic potential, particularly targeting enzymes such as aldose reductase (ALR2) and protein tyrosine phosphatase 1B (PTP1B). The research also encompasses antimicrobial agents, lipoxygenase inhibitors, and therapeutic strategies for conditions like diabetes mellitus and sepsis.

Publications Top Notes šŸ“

  • A Molecular Hybridization Approach for the Design of Selective Aldose Reductase (ALR2) Inhibitors and Exploration of Their Activities Against Protein Tyrosine Phosphatase 1B (PTP1B)
    • Authors: Kousaxidis, A., Petrou, A., Rouvim, P., Nicolaou, I., Geronikaki, A.
    • Journal: Journal of Molecular Structure
    • Year: 2023
    • Volume: 1271
    • Article Number: 134116
    • Citations: 3
    • Summary: This study presents a hybridization approach to develop selective ALR2 inhibitors and investigates their potential activities against PTP1B, highlighting their dual therapeutic potential.

 

  • Design, Synthesis, and Pharmacological Evaluation of Indazole Carboxamides of N-Substituted Pyrrole Derivatives as Soybean Lipoxygenase Inhibitors
    • Authors: Lavrentaki, V., Kousaxidis, A., Theodosis-Nobelos, P., Koutsopoulos, K., Nicolaou, I.
    • Journal: Molecular Diversity
    • Year: 2023
    • Citations: 2
    • Summary: This paper discusses the synthesis and evaluation of novel indazole carboxamides, demonstrating significant inhibitory activity against soybean lipoxygenase.

 

  • N-Derivatives of (Z)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1H-indole-2-carboxylates as Antimicrobial Agentsā€”In Silico and In Vitro Evaluation
    • Authors: Petrou, A., Geronikaki, A., Kartsev, V., Nicolaou, I., Vizirianakis, I.S.
    • Journal: Pharmaceuticals
    • Year: 2023
    • Volume: 16
    • Issue: 1
    • Article Number: 131
    • Citations: 4
    • Summary: This open-access article evaluates the antimicrobial activity of new N-derivatives, supported by both in silico and in vitro methods.

 

  • Non-acidic Bifunctional Benzothiazole-Based Thiazolidinones with Antimicrobial and Aldose Reductase Inhibitory Activity as a Promising Therapeutic Strategy for Sepsis
    • Authors: Kousaxidis, A., Kovacikova, L., Nicolaou, I., Stefek, M., Geronikaki, A.
    • Journal: Medicinal Chemistry Research
    • Year: 2021
    • Volume: 30
    • Issue: 10
    • Pages: 1837-1848
    • Citations: 13
    • Summary: This research explores benzothiazole-based thiazolidinones with dual activity, suggesting a promising approach for treating sepsis.

 

  • Aldose Reductase and Protein Tyrosine Phosphatase 1B Inhibitors as a Promising Therapeutic Approach for Diabetes Mellitus
    • Authors: Kousaxidis, A., Petrou, A., Lavrentaki, V., Nicolaou, I., Geronikaki, A.
    • Journal: European Journal of Medicinal Chemistry
    • Year: 2020
    • Volume: 207
    • Article Number: 112742
    • Citations: 39
    • Summary: This review highlights the potential of targeting ALR2 and PTP1B as a therapeutic strategy for diabetes, emphasizing recent advances and future perspectives.